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The Lancet Child & Adolescent Health
@lancetchildadol.bsky.social
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A vital voice for improving young lives, The Lancet Child & Adolescent Health publishes top quality research and trusted comment and opinion.

🌐 https://www.thelancet.com/journals/lanchi/home
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The Lancet Child & Adolescent Health @lancetchildadol.bsky.social · Sep 3
Our October 2025 issue is now live with content on #consent in #neonatal #clinicaltrials, growth trajectories in #twins, an #RCT on #CPAP delivery in #preterm #infants, & more

Read the full issue here👉 bit.ly/3JDzc8t

#MedSky #PedSky
Oct 2025 Volume 9 Number 10 p685-752 Cover image by Jhoan Mosquera Suarez, age 6 years. A rainbow and apple tree overlook mountains and sea.
Reposted by The Lancet Child & Adolescent Health
thelancetneuro.bsky.social
Our October issue is out - featuring biomarkers for sudden unexpected death in epilepsy, developments in the diagnosis of multiple sclerosis, climate change & brain health and much more!

Check it out here: tinyurl.com/3z5u36e7

#Neurology #BrainHealth
September 19, 2025 at 11:55 AM
Reposted by The Lancet Child & Adolescent Health
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With global obesity prevalence surpassing that of underweight among children & adolescents, harmful food environments & weak policies threaten lifelong health.

What can we do to address this global health crisis?

Find out more in our latest Editorial: tinyurl.com/3cnvctkv
Girl with healthy meal on tray at school cafeteria. Copyright: Westend61/Getty Images.
September 19, 2025 at 2:02 PM
Reposted by The Lancet Child & Adolescent Health
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Published in The Lancet @thelancet.com:

The future of type 1 #diabetes therapy www.thelancet.com/journals/lan...
#T1D
#OpenAccess

#MedSky #EndoSky
September 20, 2025 at 3:30 PM
Reposted by The Lancet Child & Adolescent Health
thelancetendo.bsky.social
In The Lancet @thelancet.com:
Minimum effective low dose of antithymocyte globulin in people aged 5–25 years with recent-onset stage 3 type 1 #diabetes (MELD-ATG): a phase 2, multicentre, double-blind, randomised, placebo-controlled, adaptive dose-ranging trial www.thelancet.com/journals/lan... #T1D
Minimum effective low dose of antithymocyte globulin in people aged 5–25 years with recent-onset stage 3 type 1 diabetes (MELD-ATG): a phase 2, multicentre, double-blind, randomised, placebo-controlle...
In young people with recent-onset, clinical type 1 diabetes, 2·5 mg/kg and 0·5 mg/kg ATG reduced loss of β-cell function, showing the potential of an affordable, repurposed agent, ATG, in a low and sa...
www.thelancet.com
September 20, 2025 at 3:38 PM
Reposted by The Lancet Child & Adolescent Health
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Join Zoë Mullan and other Lancet Group editors to learn more about the SAGER guidelines for sex- and gender-based analyses, explore real research examples, and gain practical tips for responding to the guidelines.

📅 21 October, 2pm BST
👉 Register: hubs.li/Q03FQ_6l0
Join our Lancet Webinar on the importance of analysing, reporting, and interpreting data according to sex and gender. Copyright: Elsevier Ltd.
September 23, 2025 at 8:33 AM
Reposted by The Lancet Child & Adolescent Health
thelancetrheum.bsky.social
Our October issue is live!

Including research on #vaccination in #rheumatoidarthritis and
#hydroxychloroquine during #pregnancy, two Reviews on #VEXAS, plus much more! thelancet.com/journals/lan...
Cover by Sara Gironi Carnevale #Medsky #Rheumsky
September 23, 2025 at 11:20 AM
Reposted by The Lancet Child & Adolescent Health
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NCDs affect more than 2 billion children and adolescents each year.

In a new letter, authors call for a shift from generalised #NCD strategies to specific, child-centred commitments backed by:
➡️ Global frameworks
➡️ Measurable targets
➡️ Long-term investment

🔗 tinyurl.com/3ryn7w74
Quote from a correspondence published in The Lancet entitled 'Improving survival and reducing suffering for children with NCDs.' Quote reads: [The Fourth High-level Meeting of the UN General Assembly6 on the prevention and control of NCDs] is an opportunity to galvanise a global movement for children with chronic and catastrophic diseases, especially cancers and sickle cell disease, and ensure they are no longer left behind.
September 25, 2025 at 9:18 AM
Reposted by The Lancet Child & Adolescent Health
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Read our October issue!

Featuring a trial testing moxidectin for lymphatic filariasis, bedaquiline resistance and tuberculosis outcomes, and a recombinant influenza vaccine for children.

www.thelancet.com/issue/S1473-...
September 25, 2025 at 1:22 PM
lancetchildadol.bsky.social
New online: Late effects after high-risk #neuroblastoma (LEAHRN): a multicentre, cross-sectional cohort study from the Children's Oncology Group

bit.ly/48zRnpK

@danafarber.bsky.social @sickkidsto.bsky.social @childrensphila.bsky.social @stjuderesearch.bsky.social @cityofhope.bsky.social
Late effects after high-risk neuroblastoma (LEAHRN): a multicentre, cross-sectional cohort study from the Children's Oncology Group
Survivors of high-risk neuroblastoma treated with modern therapies demonstrated a substantial burden of late effects, providing crucial information for future care and clinical trial design.
www.thelancet.com
September 26, 2025 at 8:36 AM
lancetchildadol.bsky.social
Explore the new data on the global burden of #cancer in children, adolescents, & young adults

"Childhood cancers occurring in the 0–14 year age range comprised 1·4% of all cancer cases and 1·0% of all cancer deaths globally in 2023, but 3·2% of all cancer DALYs"

Childhood Cancer Awareness Month
thelancet.com The Lancet @thelancet.com · Sep 25
Cancer deaths expected to rise to over 18 million in 2050—an increase of nearly 75% from 2024, study forecasts.

Explore the data ▶️ tinyurl.com/5n7dfnws @ihmeuw.bsky.social #NCDs
Figure: Global age-specific cancer (A) incidence and (B) mortality in 2023 for all sexes combined. Results are presented by 5-year age group. Left panels present age-specific incidence and mortality rates. Right panels present age-specific new case and death proportions. Copyright: 2025 Elsevier Ltd. All rights are reserved.
September 26, 2025 at 8:28 AM
lancetchildadol.bsky.social
Our editorial, published in advance of our November issue, discusses challenges around quality of life in #childhoodcancer in the context of global child & adolescent health

#free to read

www.thelancet.com/journals/lan...

Childhood Cancer Awareness Month #PedSky #OncSky
Surviving and thriving after childhood cancer
Without treatment, childhood cancer is fatal. However, in regions and settings with access to safe and effective therapies and supportive care, it is eminently survivable. But survival comes at the co...
www.thelancet.com
September 26, 2025 at 8:23 AM
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thelancet.com
📢 Join our webinar on sex and gender reporting in research

📅 Tues, 21 October, 2pm BST
👉 Register: hubs.li/Q03FQ_6l0

Our editors will guide you through our requirements for sex- and gender-based analyses, and share practical tips and examples of well-analysed research
Join our webinar on the importance of analysing, reporting, and interpreting data according to sex and gender on Tues, Oct 21, 2025 at 2pm BST/9am EDT. The Lancet Webinars. Copyright: Elsevier Ltd.
September 17, 2025 at 9:31 AM
Reposted by The Lancet Child & Adolescent Health
thelancetinfdis.bsky.social
New Research:

Safety, tolerability, and protective efficacy of a radiation-attenuated, whole sporozoite malaria vaccine in children in Gabon: a randomised, double-blind, placebo-controlled, phase 2 trial

www.thelancet.com/journals/lan...
Safety, tolerability, and protective efficacy of a radiation-attenuated, whole sporozoite malaria vaccine in children in Gabon: a randomised, double-blind, placebo-controlled, phase 2 trial
PfSPZ Vaccine is well tolerated and safe, but it did not prevent P falciparum infection in children in Gabon. Whether presumptive treatment during immunisation or more potent PfSPZ vaccines can establ...
www.thelancet.com
September 17, 2025 at 9:55 AM
lancetchildadol.bsky.social
All clinical research and review in child & adolescent health across @thelancet.com group conveniently in one place 👇

www.thelancet.com/collections/...

#PedSky
September 16, 2025 at 4:11 PM
Reposted by The Lancet Child & Adolescent Health
thelancet.com
Parent-focused programs insufficient to prevent obesity in toddlers, finds meta-analysis; authors call for a re-think of childhood obesity prevention approaches.

Explore the research ▶️ tinyurl.com/4mxaaypx
Parent-focused behavioural interventions for the prevention of early childhood obesity (TOPCHILD): a systematic review and individual participant data meta-analysis
These findings indicate that examined parent-focused behavioural interventions are insufficient to prevent obesity at age 24 months (±6 months). This evidence highlights a need to re-think childhood o...
tinyurl.com
September 16, 2025 at 11:01 AM
lancetchildadol.bsky.social
New research from Nicolas Menzies & colleagues: Potential #paediatric #tuberculosis incidence and deaths resulting from interruption in programmes supported by international health aid, 2025–34: a mathematical modelling study

www.thelancet.com/journals/lan...

#PedSky #InternationalAid
Potential paediatric tuberculosis incidence and deaths resulting from interruption in programmes supported by international health aid, 2025–34: a mathematical modelling study
Without actions to restore discontinued services, cuts to health aid for tuberculosis and HIV programmes could result in millions of additional childhood tuberculosis cases and deaths in low-income an...
www.thelancet.com
September 16, 2025 at 4:07 PM
Reposted by The Lancet Child & Adolescent Health
thelancet.com
Shigellosis is the most common cause of invasive bloody diarrhoea in children younger than 5 years.

The prevention of infection with vaccination & sanitation strategies remains a crucial step in reducing worldwide morbidity & mortality.

Find out more ▶️ tinyurl.com/ard69t83
Figure showing the immunopathogenesis of Shigella infection in the colon. MAMPs=microbe-associated molecular patterns. DAMPs=damage-associated molecular patterns. NK=natural killer. Adapted from Schnupf and Sansonetti. Copyright: 2025 Elsevier Ltd. All rights are reserved.
September 12, 2025 at 1:58 PM
lancetchildadol.bsky.social
💡A new systematic review & meta-analysis in @thelancet.com concludes that "parent-focused behavioural interventions are insufficient to prevent obesity at age 24 months" suggesting that childhood obesity prevention approaches "need a re-think"

www.thelancet.com/journals/lan...

#MedSky #PedSky
Parent-focused behavioural interventions for the prevention of early childhood obesity (TOPCHILD): a systematic review and individual participant data meta-analysis
These findings indicate that examined parent-focused behavioural interventions are insufficient to prevent obesity at age 24 months (±6 months). This evidence highlights a need to re-think childhood o...
www.thelancet.com
September 12, 2025 at 9:18 AM
lancetchildadol.bsky.social
In advance of #WorldSepsisDay, a Reflection from Akash Deep & Melissa Mead

www.thelancet.com/journals/lan...

#SepsisAwarenessMonth
Beyond sepsis awareness: why some children still fall through the cracks
In 2014, when William Mead unexpectedly died of sepsis at just 12 months old, his mother, Melissa, transformed her grief into a relentless mission. She stepped into a world she had never imagined: end...
www.thelancet.com
September 12, 2025 at 8:58 AM
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thelancetoncol.bsky.social
🚨Our Sept issue is live - 25 years! thelancet.com/journals/lan...

📊Articles #renalcellcarcinoma, #prostatecancer, #meningioma, #thymiccarcinoma, & #colorectalcancer

Reviews: 📰 ESTRO and ASTRO plus endorsed guidelines on vol delineation & 📰 Common Sense Oncology and EORTC on reporting QoL data
September 12, 2025 at 8:23 AM
lancetchildadol.bsky.social
*NEW* Health Policy from Morris Gordon & colleagues: European and North American guidelines for treating irritable bowel syndrome and functional abdominal pain in childhood: a guide for health-care professionals

www.thelancet.com/journals/lan...

#MedSky #PedSky #GastroSky
European and North American guidelines for treating irritable bowel syndrome and functional abdominal pain in childhood: a guide for health-care professionals
Abdominal pain-related disorders of gut–brain interaction (AP-DGBI; including irritable bowel syndrome, functional abdominal pain—not otherwise specified, abdominal migraine, and functional dyspepsia)...
www.thelancet.com
September 10, 2025 at 9:29 AM
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thelancetrheum.bsky.social
NEW RESEARCH—Serum biomarkers associated with baricitinib response in patients with juvenile idiopathic arthritis: a post-hoc analysis of the phase 3 JUVE-BASIS trial bit.ly/4nrPIqK #JIA #Medsky #Rheumsky
September 9, 2025 at 2:47 PM
Reposted by The Lancet Child & Adolescent Health
thelancetendo.bsky.social
Our October Issue is now online, featuring prediabetes remission, obesity, type 1 diabetes, biased GLP-1 receptor agonists, type 2 diabetes, prolactin-secreting adenomas, malnutrition-related diabetes, food system, NCDs & much more www.thelancet.com/journals/lan...

#MedSky #EndoSky #OncSky
September 9, 2025 at 10:35 PM
Reposted by The Lancet Child & Adolescent Health
eclinicalmed.bsky.social
Comparison of predictive tools for management of paediatric mild #TBI: a prospective cohort study

Despite assumed similarities of these predictive tools, there are important differences in diagnostic performance, practical application and clinical impact

www.thelancet.com/journals/ecl...
#MedSky
September 8, 2025 at 11:44 AM
Reposted by The Lancet Child & Adolescent Health
lancetmicrobe.bsky.social
Our September issue is now online:

www.thelancet.com/journals/lan...

Our journal is #OpenAccess, so you are free to explore all of our content. But these hashtags offer a flavour: #SARS-CoV-2 #HIV #Pneumocystis #tuberculosis #TB #gonorrhoea #Citrobacter #AMR #Salmonella

#IDSky #ClinMicro #OA
Cover of The Lancet Microbe's September issue with a "Light micrograph of a lung sample from an AIDS patient showing cysts of Pneumocystis [jirovecii]".
September 9, 2025 at 8:35 AM