LabSoap
@labsoap.bsky.social
S.O.A.P. Team in Nantes, France
Led by Julie Gavard & Nicolas Bidere
Signaling in Oncogenesis, Angiogenesis, and Permeability
#glioblastoma #cancer #research
Led by Julie Gavard & Nicolas Bidere
Signaling in Oncogenesis, Angiogenesis, and Permeability
#glioblastoma #cancer #research
Pinned
This week #JournalClub @labsoap.bsky.social @cellpress.bsky.social #glioblastoma #immune_responses #meningeal_vessels www.cell.com/cell/abstrac...
Meningeal blood vessel blockage enhances anti-glioblastoma immunity
Meningeal blood vessel blockage enhances anti-tumor immunity against GBM in preclinical
models by expanding dural resident border-associated macrophages, which are equipped
with an elevated antigen-pr...
www.cell.com
February 9, 2026 at 10:48 PM
This week #JournalClub @labsoap.bsky.social @nature.com #integrin #tetraspanin #migration www.science.org/doi/10.1126/...
Platelet-derived integrin- and tetraspanin-enriched tethers exacerbate severe inflammation
Platelet integrin αIIbβ3 is essential for hemostasis, thrombosis, and inflammation. We found that ligation of αIIbβ3 by von Willebrand factor or fibrin under flow triggered its accumulation in plasma ...
www.science.org
February 2, 2026 at 7:44 PM
This week #JournalClub @labsoap.bsky.social @science.org #glioblastoma #IDH1 www.science.org/doi/10.1126/...
IDH-mutant gliomas arise from glial progenitor cells harboring the initial driver mutation
Identifying the cell of origin that harbors an initial driver mutation is key to understanding tumor evolution and for the development of new treatments. For isocitrate dehydrogenase (IDH)–mutant glio...
www.science.org
January 26, 2026 at 8:16 PM
This week #JournalClub @labsoap.bsky.social #lysosomes #ER #secretion @nature.com www.nature.com/articles/s41...
Secretome translation shaped by lysosomes and lunapark-marked ER junctions - Nature
Live-cell imaging of mRNA encoding secretome proteins and translated nascent peptide markers show that secretome translation occurs at endoplasmic reticulum junctions near lysosomes, requires lun...
www.nature.com
January 19, 2026 at 6:22 PM
This week #JournalClub @labsoap.bsky.social @nature.com #celldeath #plasmamembrane #rupture #MLKL #necroptosis www.nature.com/articles/s41...
Client Challenge
www.nature.com
January 12, 2026 at 6:01 PM
This week #JournalClub @labsoap.bsky.social #glioblastoma #microbiota @natureportfolio.nature.com www.nature.com/articles/s41...
Microbial signals in primary and metastatic brain tumors - Nature Medicine
A combination of high-resolution spatial imaging, spatial proteomics and transcriptional data reveals sparse and heterogeneous bacterial signals in gliomas and brain metastases.
www.nature.com
January 6, 2026 at 8:53 AM
December 15, 2025 at 12:38 PM
This week #JournalClub @cellpress.bsky.social #membrane #pressure #Hippo #density www.sciencedirect.com/science/arti...
Membrane potential mediates the cellular response to mechanical pressure
Mechanical forces influence cellular decisions to grow, die, or differentiate, through largely mysterious mechanisms. Separately, changes in resting m…
www.sciencedirect.com
December 9, 2025 at 5:43 PM
Reposted by LabSoap
Reposted by LabSoap
Reposted by LabSoap
Just Published!
Spatiotemporal Analysis of Glucagon Secretory Granule Dynamics - Ghignoli - 2025 - Traffic - Wiley Online Library onlinelibrary.wiley.com/doi/abs/10.1...
Spatiotemporal Analysis of Glucagon Secretory Granule Dynamics - Ghignoli - 2025 - Traffic - Wiley Online Library onlinelibrary.wiley.com/doi/abs/10.1...
onlinelibrary.wiley.com
October 23, 2025 at 3:03 PM
Just Published!
Spatiotemporal Analysis of Glucagon Secretory Granule Dynamics - Ghignoli - 2025 - Traffic - Wiley Online Library onlinelibrary.wiley.com/doi/abs/10.1...
Spatiotemporal Analysis of Glucagon Secretory Granule Dynamics - Ghignoli - 2025 - Traffic - Wiley Online Library onlinelibrary.wiley.com/doi/abs/10.1...
Reposted by LabSoap
Just Published !
Virion Associated Importin Subunit Beta‐1 Augments Nuclear Import of HIV‐1 Pre‐Integration Complex - Yandrapally - 2025 - Traffic - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
Virion Associated Importin Subunit Beta‐1 Augments Nuclear Import of HIV‐1 Pre‐Integration Complex - Yandrapally - 2025 - Traffic - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
October 23, 2025 at 3:04 PM
Just Published !
Virion Associated Importin Subunit Beta‐1 Augments Nuclear Import of HIV‐1 Pre‐Integration Complex - Yandrapally - 2025 - Traffic - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
Virion Associated Importin Subunit Beta‐1 Augments Nuclear Import of HIV‐1 Pre‐Integration Complex - Yandrapally - 2025 - Traffic - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
Reposted by LabSoap
This week #JournalClub @labsoap.bsky.social @science.org #LYVAC #vacuole #lysosome www.science.org/doi/10.1126/...
LYVAC/PDZD8 is a lysosomal vacuolator
Lysosomal vacuolation is commonly found in many pathophysiological conditions, but its molecular mechanisms and functions remain largely unknown. Here, we show that the endoplasmic reticulum (ER)–anch...
www.science.org
November 10, 2025 at 4:54 PM
@labsoap.bsky.social back from #Turku #0carbon #greencity #Finland for a very neat and excellent meeting on #braintumor #glioblastoma @fibtra.bsky.social
October 30, 2025 at 9:52 AM
@labsoap.bsky.social back from #Turku #0carbon #greencity #Finland for a very neat and excellent meeting on #braintumor #glioblastoma @fibtra.bsky.social
This week #JournalClub @labsoap.bsky.social www.science.org/doi/10.1126/... #inflammation #STING #sensing @science.org
MTAP deficiency confers resistance to cytosolic nucleic acid sensing and STING agonists
Cytosolic nucleic acid–sensing pathways are potential targets for cancer immunotherapy. Although stimulator of interferon genes (STING) agonists have shown substantial antitumor effects in animal mode...
www.science.org
October 29, 2025 at 2:48 PM
This week #JournalClub @labsoap.bsky.social #DNArepair #cGAS #STING @science.org #molerat 🐀 www.science.org/doi/10.1126/...
October 20, 2025 at 2:42 PM
This week #journalclub @labsoap.bsky.social @naturemetabolism.bsky.social @agostinislab.bsky.social #Lysosome #ferroptosis #mitochondria www.nature.com/articles/s42...
Client Challenge
www.nature.com
October 13, 2025 at 4:16 PM
This week #JournalClub @labsoap.bsky.social #Immunotherapy #resistance #cancerneuroscience @nature.com www.nature.com/articles/s41...
Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy - Nature
Perineural invasion and cancer-induced nerve injury of tumour-associated nerves are associated with poor response to anti-PD-1 therapy, which can be reversed by combining anti-PD-1 therapy with anti-inflammatory interventions.
www.nature.com
September 29, 2025 at 7:41 AM
This week #JournalClub @labsoap.bsky.social @nature.com #glioblastoma #injury #neuroscience #initiation #progression www.nature.com/articles/s41...
Axonal injury is a targetable driver of glioblastoma progression - Nature
Axonal injury, induced in the white matter by expansion of early tumour cells, is a key driver of glioblastoma progression.
www.nature.com
September 15, 2025 at 7:55 AM
Reposted by LabSoap
Editor's selected articles of the last two years onlinelibrary.wiley.com/doi/toc/10.1...
Editors Choice Articles: Traffic
Traffic is a cell biology and biochemistry journal devoted to intracellular transport, covering subcellular trafficking, membrane dynamics, organelle function & more.
onlinelibrary.wiley.com
September 3, 2025 at 7:11 AM
Editor's selected articles of the last two years onlinelibrary.wiley.com/doi/toc/10.1...
This week #JournalClub @labsoap.bsky.social #mitophagy #differentiation #stemness #cancer @nature.com www.nature.com/articles/s41...
DHRS13 suppresses differentiation and mitophagy in glioma via retinoic acid and mitochondrial reactive oxygen species - Nature Communications
Cancer stem-like cells contribute to tumor growth and therapy resistance in glioblastoma. Here, authors identify that DHRS13 inhibition promotes differentiation of glioma stem-like cells by activating...
www.nature.com
September 1, 2025 at 7:03 PM