@krisvleminckx.bsky.social
Cell and Developmental Biologist @Ghent
University | Xenopus aficionado | Human genetic disease modeling | Cancer and Rare Diseases
Ghent, Belgium
University | Xenopus aficionado | Human genetic disease modeling | Cancer and Rare Diseases
Ghent, Belgium
I had the privilege to interact with desmoid tumor patients at the annual #DTRF meeting in Chicago. An inspiring & motivating event! Great to talk to Athina Merckx, granddaughter of the greatest Belgian cyclist ever, brave desmoid patient and fantastic fundraiser #Athinasride
@crighent.bsky.social
@crighent.bsky.social
September 14, 2025 at 2:35 AM
I had the privilege to interact with desmoid tumor patients at the annual #DTRF meeting in Chicago. An inspiring & motivating event! Great to talk to Athina Merckx, granddaughter of the greatest Belgian cyclist ever, brave desmoid patient and fantastic fundraiser #Athinasride
@crighent.bsky.social
@crighent.bsky.social
Reposted
How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭
Check out our paper - fresh off the press!!!
We find widespread functional conservation of enhancers in absence of sequence homology
Including: a bioinformatic tool to map sequence-diverged enhancers!
rdcu.be/enVDN
github.com/tobiaszehnde...
Check out our paper - fresh off the press!!!
We find widespread functional conservation of enhancers in absence of sequence homology
Including: a bioinformatic tool to map sequence-diverged enhancers!
rdcu.be/enVDN
github.com/tobiaszehnde...
Conservation of regulatory elements with highly diverged sequences across large evolutionary distances
Nature Genetics - Combining functional genomic data from mouse and chicken with a synteny-based strategy identifies positionally conserved cis-regulatory elements in the absence of direct sequence...
rdcu.be
May 27, 2025 at 12:19 PM
How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭
Check out our paper - fresh off the press!!!
We find widespread functional conservation of enhancers in absence of sequence homology
Including: a bioinformatic tool to map sequence-diverged enhancers!
rdcu.be/enVDN
github.com/tobiaszehnde...
Check out our paper - fresh off the press!!!
We find widespread functional conservation of enhancers in absence of sequence homology
Including: a bioinformatic tool to map sequence-diverged enhancers!
rdcu.be/enVDN
github.com/tobiaszehnde...
Reposted
We are hiring #postdocs and #phd students in the areas of #devbio #cellbio #Bioinformatics #mathematics #modeling.
This is the full add with details:
euraxess.de/jobs/346670
This our lab homepage:
www.uniklinik-freiburg.de/walentek-en....
This is the full add with details:
euraxess.de/jobs/346670
This our lab homepage:
www.uniklinik-freiburg.de/walentek-en....
Multiple Postdoc and PhD positions in developmental biology, genetics, bioinformatics and mathematical modeling - Walentek Lab - Freiburg, Germany
University Freiburg Medical Center is a leading institution in biomedical research in the heart of Europe with close associations to other institutions and centers in the tri-national Eucor area (Germ...
euraxess.de
May 27, 2025 at 6:38 AM
We are hiring #postdocs and #phd students in the areas of #devbio #cellbio #Bioinformatics #mathematics #modeling.
This is the full add with details:
euraxess.de/jobs/346670
This our lab homepage:
www.uniklinik-freiburg.de/walentek-en....
This is the full add with details:
euraxess.de/jobs/346670
This our lab homepage:
www.uniklinik-freiburg.de/walentek-en....
Reposted
Paper Alert!! Last year we reported on ZFHX3 loss of function (LoF), today we report that also ZFHX4 LoF is associated with an NDD. Great collaboration the ZFHX4 consortium, excellently led by María del Rocío Perez Baca and María Palomares. As always great collab with co-supervisor Bert Callewaert.
📣New from @svergult.bsky.social & co
📄Loss of function of the zinc finger homeobox 4 gene, ZFHX4, underlies a neurodevelopmental disorder
📄Loss of function of the zinc finger homeobox 4 gene, ZFHX4, underlies a neurodevelopmental disorder
Loss of function of the zinc finger homeobox 4 gene, ZFHX4, underlies a neurodevelopmental disorder
We associate ZFHX4 loss of function with syndromic intellectual disability. While
ZFHX4 deletions showed a mild methylation profile, protein-truncating variants did
not. Multi-omics data implicate ZFH...
www.cell.com
May 13, 2025 at 7:11 PM
Paper Alert!! Last year we reported on ZFHX3 loss of function (LoF), today we report that also ZFHX4 LoF is associated with an NDD. Great collaboration the ZFHX4 consortium, excellently led by María del Rocío Perez Baca and María Palomares. As always great collab with co-supervisor Bert Callewaert.
Reposted
During embryonic development, we need to build brains that contain a huge diversity of different types of neurons and glia. Single-cell studies tell us that there are more than 3000 kinds of neurons in the brain, and as many as 120-130 in the eye.
www.jneurosci.org/content/40/2...
www.jneurosci.org/content/40/2...
Mouse Retinal Cell Atlas: Molecular Identification of over Sixty Amacrine Cell Types
Amacrine cells (ACs) are a diverse class of interneurons that modulate input from photoreceptors to retinal ganglion cells (RGCs), rendering each RGC type selectively sensitive to particular visual fe...
www.jneurosci.org
January 18, 2025 at 1:44 PM
During embryonic development, we need to build brains that contain a huge diversity of different types of neurons and glia. Single-cell studies tell us that there are more than 3000 kinds of neurons in the brain, and as many as 120-130 in the eye.
www.jneurosci.org/content/40/2...
www.jneurosci.org/content/40/2...
Reposted
Aanandita Kothurkar, @colinchulab.bsky.social, Ryan MacDonald and colleagues @ucleye.bsky.social apply IBEX to simultaneously identify all the major retinal cell types.
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
December 16, 2024 at 10:51 AM
Aanandita Kothurkar, @colinchulab.bsky.social, Ryan MacDonald and colleagues @ucleye.bsky.social apply IBEX to simultaneously identify all the major retinal cell types.
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
Reposted
We have just launched a call for our PhD excellence award 2025! This 5000 Euro prize wants to reward a young scientist for outstanding achievements in cell and/or developmental biology [PhD done in a Belgian lab]. Deadline March 1, 2025. bscdb.be/phd-excellen...
RBSCDB PhD Excellence Award | Belgian Society for Cell and Developmental Biology
bscdb.be
December 3, 2024 at 6:26 PM
We have just launched a call for our PhD excellence award 2025! This 5000 Euro prize wants to reward a young scientist for outstanding achievements in cell and/or developmental biology [PhD done in a Belgian lab]. Deadline March 1, 2025. bscdb.be/phd-excellen...
Reposted
By definition, enhancers can activate from a distance. But with increased distance between enhancer and promoter, the activation drops. To study this systematically, we build a synthetic locus: www.cell.com/molecular-ce... 1/12
Redirecting
doi.org
December 2, 2024 at 4:44 PM
By definition, enhancers can activate from a distance. But with increased distance between enhancer and promoter, the activation drops. To study this systematically, we build a synthetic locus: www.cell.com/molecular-ce... 1/12
With a little help of my very own offspring as stand-in instructor
November 24, 2024 at 6:31 PM
With a little help of my very own offspring as stand-in instructor
The excitement of watching #Xenopus embryos' early development at Ghent University's Science Day .... and recruiting a future generation of PhD students🐸 @ds-ugent.bsky.social @frogwranglers.bsky.social
November 24, 2024 at 6:17 PM
The excitement of watching #Xenopus embryos' early development at Ghent University's Science Day .... and recruiting a future generation of PhD students🐸 @ds-ugent.bsky.social @frogwranglers.bsky.social