Kelsey Person
@kelseyperson.bsky.social
UMN Neuro PhD Candidate🧠
Reposted by Kelsey Person
#SfN2025 here we come! I am thrilled to be joined at the Society for Neuroscience meeting this year by Madelyn Moore, @kelseyperson.bsky.social, @valeriarobleto.bsky.social, and Crystal Lemchi. If you are in San Diego for the conference, please stop by to say hi! 👋 🧪🧠🟦
November 14, 2025 at 7:17 PM
#SfN2025 here we come! I am thrilled to be joined at the Society for Neuroscience meeting this year by Madelyn Moore, @kelseyperson.bsky.social, @valeriarobleto.bsky.social, and Crystal Lemchi. If you are in San Diego for the conference, please stop by to say hi! 👋 🧪🧠🟦
Reposted by Kelsey Person
Scientists at Sanford Burnham Prebys, the University of Minnesota and Duke University report in Nature that “biased modulators” can target GPCRs more precisely—expanding potential drug targets and reducing side effects. www.nature.com/articles/s41...
November 3, 2025 at 8:07 PM
Scientists at Sanford Burnham Prebys, the University of Minnesota and Duke University report in Nature that “biased modulators” can target GPCRs more precisely—expanding potential drug targets and reducing side effects. www.nature.com/articles/s41...
Reposted by Kelsey Person
Newly designed molecules acting as "molecular glues" and "bumpers" can selectively rewire GPCR signaling, offering a pathway to more precise and potentially safer medicines. doi.org/g98xfp
'Molecular glues' and 'bumpers' offer new hope for precision medicines
New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, turning the cell's busiest receptors into precision tools—opening the door to a new generation of safer, smarter medicines.
medicalxpress.com
November 2, 2025 at 8:46 PM
Newly designed molecules acting as "molecular glues" and "bumpers" can selectively rewire GPCR signaling, offering a pathway to more precise and potentially safer medicines. doi.org/g98xfp
Reposted by Kelsey Person
Nature research paper: Designing allosteric modulators to change GPCR G protein subtype selectivity
go.nature.com/49jaBQS
go.nature.com/49jaBQS
Designing allosteric modulators to change GPCR G protein subtype selectivity - Nature
Studies of the G-protein-coupled receptor NTSR1 show that the G protein selectivity of this receptor can be modified by small molecules, enabling the design of drugs that work by switching receptor subtype preference.
go.nature.com
October 28, 2025 at 2:36 PM
Nature research paper: Designing allosteric modulators to change GPCR G protein subtype selectivity
go.nature.com/49jaBQS
go.nature.com/49jaBQS
Excited to share that my co–first author paper has been accepted in @nature.com 🎉
We show that small molecules binding at the GPCR-transducer interface can predictably switch G protein selectivity - paving the way for structure-guided, pathway-selective drug design.
www.nature.com/articles/s41...
We show that small molecules binding at the GPCR-transducer interface can predictably switch G protein selectivity - paving the way for structure-guided, pathway-selective drug design.
www.nature.com/articles/s41...
Designing allosteric modulators to change GPCR G protein subtype selectivity - Nature
Studies of the G-protein-coupled receptor NTSR1 show that the G protein selectivity of this receptor can be modified by small molecules, enabling the design of drugs that work by switching receptor su...
www.nature.com
October 22, 2025 at 3:44 PM
Excited to share that my co–first author paper has been accepted in @nature.com 🎉
We show that small molecules binding at the GPCR-transducer interface can predictably switch G protein selectivity - paving the way for structure-guided, pathway-selective drug design.
www.nature.com/articles/s41...
We show that small molecules binding at the GPCR-transducer interface can predictably switch G protein selectivity - paving the way for structure-guided, pathway-selective drug design.
www.nature.com/articles/s41...
Reposted by Kelsey Person
🎉BIN is turning 5️⃣—and going in-person for Black In Neuro Conference 2025 in Washington, DC 🧠✨
🗓️ It's time to save the date: September 10-12, 2025
Let’s celebrate 5 years of community, connection, and Black excellence in neuroscience!
More details to come soon!! 🤗
🗓️ It's time to save the date: September 10-12, 2025
Let’s celebrate 5 years of community, connection, and Black excellence in neuroscience!
More details to come soon!! 🤗
May 8, 2025 at 6:28 PM
🎉BIN is turning 5️⃣—and going in-person for Black In Neuro Conference 2025 in Washington, DC 🧠✨
🗓️ It's time to save the date: September 10-12, 2025
Let’s celebrate 5 years of community, connection, and Black excellence in neuroscience!
More details to come soon!! 🤗
🗓️ It's time to save the date: September 10-12, 2025
Let’s celebrate 5 years of community, connection, and Black excellence in neuroscience!
More details to come soon!! 🤗
Reposted by Kelsey Person
Our 28-yr U-RISE/MARC NIH grant that has served over 500 students and made us one of the top institutions producing African American students who go on to receive MD/PhDs in the United States was just cancelled yesterday. What a unnecessary and tragic end to such an impactful program...
March 28, 2025 at 8:56 PM
Our 28-yr U-RISE/MARC NIH grant that has served over 500 students and made us one of the top institutions producing African American students who go on to receive MD/PhDs in the United States was just cancelled yesterday. What a unnecessary and tragic end to such an impactful program...
Excited to share this! Check it out!👇🏾👇🏾
Can we design allosteric modulators that change a GPCR's preferred G protein? Yes!💥
BAMs at the GPCR-transducer interface change G protein subtype selectivity in predictable ways, enabling rational drug design.
The lab's 1st preprint! Check it out! 🧪💊🧠🟦https://doi.org/10.1101/2024.11.20.624209
🧵👇
BAMs at the GPCR-transducer interface change G protein subtype selectivity in predictable ways, enabling rational drug design.
The lab's 1st preprint! Check it out! 🧪💊🧠🟦https://doi.org/10.1101/2024.11.20.624209
🧵👇
Design of allosteric modulators that change GPCR G protein subtype selectivity
G protein-coupled receptors (GPCRs), the largest family of drug targets, can signal through 16 subtypes of Gα proteins. Biased compounds that selectively activate therapy-relevant pathways promise to ...
doi.org
November 22, 2024 at 4:17 PM
Excited to share this! Check it out!👇🏾👇🏾
Reposted by Kelsey Person
#BlackInNeuro Starter Pack v1! Let us know if we missed you. #BlackInSTEM #Neuroscience 🧪
go.bsky.app/F8PpdPe
go.bsky.app/F8PpdPe
November 15, 2024 at 12:07 AM
#BlackInNeuro Starter Pack v1! Let us know if we missed you. #BlackInSTEM #Neuroscience 🧪
go.bsky.app/F8PpdPe
go.bsky.app/F8PpdPe