Kathryn Jacobs
kathrynjacobss.bsky.social
Kathryn Jacobs
@kathrynjacobss.bsky.social
Post doctoral fellow Bergers/Agostinis Lab
Formerly member of Lab Soap

Focus on Autophagy, Vessels, inflammation, and cancer
Thank you to the organizers of @keystonesymposia.bsky.social Autophagy meeting for the opportunity to present my post doc work #autophagy #Hevs
June 28, 2025 at 6:04 PM
Reposted by Kathryn Jacobs
👋Our June issue's out!
Cover: #Ferroptosis hotspots

👉🏼Editorial on #microscopy reporting
👉🏼Review on #mitochondria membrane
🔬 #cholesterol transport #neutrophils #exosomes #CellDeath #RNA #DNArepair #BreastCancer #ExtracellularVesicles #peroxisome proteins & more!
www.nature.com/ncb/volumes/...
June 20, 2025 at 2:19 PM
Reposted by Kathryn Jacobs
Super grateful to see our image on the June cover of
@natcellbio.nature.com representative of our work www.nature.com/articles/s41...! Many thx to @agostinislab.bsky.social and the editorial team ❤️‍🔥 www.nature.com/ncb/volumes/...
@viblifesciences.bsky.social
@kuleuvenuniversity.bsky.social
Honored to have our image @mariamls.bsky.social featured on the June cover of NCB! It's a stunning depiction of #ER-mitochondria hotspots in #ferroptosis. Huge thanks to @natcellbio.nature.com team for this awesome recognition of our work. @viblifesciences.bsky.social
www.nature.com/ncb/volumes/...
June 18, 2025 at 8:37 AM
Reposted by Kathryn Jacobs
Honored to have our image @mariamls.bsky.social featured on the June cover of NCB! It's a stunning depiction of #ER-mitochondria hotspots in #ferroptosis. Huge thanks to @natcellbio.nature.com team for this awesome recognition of our work. @viblifesciences.bsky.social
www.nature.com/ncb/volumes/...
June 18, 2025 at 7:42 AM
Reposted by Kathryn Jacobs
🚨 Where does lipid peroxidation kick off in ferroptosis? 🔥Excited to reveal ER-mitochondria contacts as hotspots of the lipid peroxidation cascade! Kudos to our Maria Livia Sassano @mariamls.bsky.social 🙏 to our amazing collaborators #Ferroptosis#contactsites#ER#mitochondria# doi.org/10.1038/s415...
Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis - Nature Cell Biology
Sassano et al. identify endoplasmic reticulum–mitochondria contact sites as the intracellular location where phospholipid peroxidation first occurs to promote ferroptosis. Manipulating these contact s...
doi.org
June 13, 2025 at 10:24 AM
Reposted by Kathryn Jacobs
💥 New study : check out @katkajerabkova.bsky.social Katka's wizardry in the lab 🧙‍♂️
Building on the #Nanotumor consortium that we launched few years back, we now provide solid evidence that melanoma cells' inner architecture controls the progression of #melanoma to #metastasis
rdcu.be/eg8EU (1/3)
Peripheral positioning of lysosomes supports melanoma aggressiveness
Nature Communications - The function and position of organelles are pivotal for tumor cell dissemination. Here the authors use melanoma patient samples and animal models to show that peripheral...
rdcu.be
April 10, 2025 at 5:40 AM
Had a great time at Cfatg’s autophagy meeting ! Thanks to the organizers for the opportunity to speak ! @cfatg.bsky.social
March 21, 2025 at 12:33 PM
Interested in studying HEVs but don’t know where to start? We’ve created some helpful tips to get you started. www.sciencedirect.com/science/arti...
Guidelines for the assessment of high endothelial venule functionality and health
High endothelial venules (HEVs) are specialized blood vessels that act as the entry point for lymphocytes into the lymph node. These vessels have a un…
www.sciencedirect.com
March 18, 2025 at 7:13 AM
Reposted by Kathryn Jacobs
We've been studying mechanisms of resilience that protect lysosomes from damage and wrote a review on the topic. We consider lysosomal stress and damage on a spectrum. Please help me share as this is my first post 😀 and I don't have many followers! 🙏 Open Access: www.embopress.org/doi/full/10....
February 27, 2025 at 3:54 PM
My PhD student Ana giving her 2nd year research seminar @bergerslab.bsky.social
December 10, 2024 at 12:24 PM