Jonas Schulte-Schrepping
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jsschrepping.bsky.social
Jonas Schulte-Schrepping
@jsschrepping.bsky.social
PostDoc at Systems Medicine, DZNE, studying innate immunity and memory in the context of inflammatory challenges using (sc)Omics technologies and bioinformatics.
Reposted by Jonas Schulte-Schrepping
🔔PhD position open. Interested in building competencies in computational biology in spatial transcriptomics? Malte Luecken's lab and I have an open PhD position, part of the Munich School of Data Science.
Application deadline: Sept 26
Link: www.mu-ds.de
MUDS - Helmholtz Information & Data Science Academy
www.mu-ds.de
September 10, 2025 at 7:06 AM
Reposted by Jonas Schulte-Schrepping
Out @nature.com: Clonal tracing with somatic epimutations

🧬 Single cell methylome encodes cell state & clonal identity

🔨 EPI-Clone reads out both (+mutations, +RNA) at scale

🩸 Clonal expansions of HSCs are universal from age 50, not driven by CH mutations

doi.org/10.1038/s415...
🧵
Clonal tracing with somatic epimutations reveals dynamics of blood ageing - Nature
The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone, an algorithm that enables single-cell lineage tracing th...
doi.org
May 21, 2025 at 3:44 PM
Reposted by Jonas Schulte-Schrepping
Read our newest publication @jem.org about #microglia and #CD8Tcell interactions in spastic paraplegia! 💡Immune activation happens before #neuronal loss! 💡
Team effort with the labs of Marc Beyer and Ralf Stumm 👇
doi.org/10.1084/jem....
@limes-bonn.bsky.social @immunosens.bsky.social #immunosky
April 23, 2025 at 2:45 PM
Reposted by Jonas Schulte-Schrepping
🍽️ Western diet causes inflammation, traditional African food protects. Study in @naturemedicine.bsky.social, close collaboration with partners from @radboudumc.bsky.social (Netherlands) 🇳🇱 and KCMC University (Tanzania) 🇹🇿

👉 www.nature.com/articles/s41...
Immune and metabolic effects of African heritage diets versus Western diets in men: a randomized controlled trial - Nature Medicine
A randomized crossover trial showed that transition to a Western diet resulted in pro-inflammatory changes, whereas transition to an African heritage diet rich in fruits and vegetables, legumes and fe...
www.nature.com
April 3, 2025 at 12:17 PM
Reposted by Jonas Schulte-Schrepping
Pressemitteilung d infektiologischen Fachgesellschaften zu den Ereignissen in den USA & den Folgen für die globale Gesundheit.
Appell an die Politik in Deutschland, Medizin + Wissenschaft vor staatlicher Zensur u. Willkür zu schützen u. internationale Zusammenarbeit zu stärken.
tinyurl.com/3fd7rtrx
February 6, 2025 at 5:20 PM