Jose Torres
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jovitope.bsky.social
Jose Torres
@jovitope.bsky.social
Neuroscientist. Ramón y Cajal researcher at @UV_EG. Epigenetics, pain & sociability. Pegolí, former Londoner. Tweets in English/Catalan/Spanish | He/him
Reposted by Jose Torres
🗞️Un equip d’investigació de @ccbiologiquesuv.bsky.social  ha demostrat que femelles de ratolí model de la síndrome de Rett, presenten alteracions significatives de les respostes comportamentals associades al dolor. 

🔗+info: https://ir.uv.es/AcNu2kI
January 26, 2026 at 9:15 AM
Reposted by Jose Torres
Os dejo por aquí la noticia que resume nuestro último trabajo, publicado la semana pasada, sobre #Rett #Mecp2 y #dolor
@uv.es @ccbiologiquesuv.bsky.social
El avance de los síntomas neurológicos altera la expresión del dolor en ratones modelo del síndrome de Rett
Un equipo de investigación de la Facultad de Ciencias Biológicas ha mostrado que hembras de ratón modelo del síndrome de Rett, una dolencia del neurodesarrollo rara y muy grave que provoca múltiples s...
www.uv.es
January 20, 2026 at 9:39 AM
Reposted by Jose Torres
There's still time to apply to be a 2026 @dev-journal.bsky.social Pathway to Independence fellow

For those about to apply for their first independent academic position, the programme offers

- mentoring
- leadership training
- profile rising
- networking

journals.biologists.com/dev/pages/pi...
Pathway to Independence programme | Development | The Company of Biologists
Pathway to Independence programme | Development | The Company of Biologists Development's Pathway to Independence programme Launched in 2022, Development’s Pathway Independence programm...
journals.biologists.com
January 13, 2026 at 5:29 PM
Reposted by Jose Torres
Gracias a @jovitope.bsky.social, por estirar de la línea sobre dolor y #Rett, y a todos los coautores @moigaren.bsky.social, @bayesana.bsky.social, y los que no están en blusqui!
January 13, 2026 at 10:01 AM
Reposted by Jose Torres
Por fin on-line nuestro último paper!
En este estudio, parte del cual fue la tesis de Elena Martínez, investigamos la sensibilidad y el dolor en ratonas mutantes para #Mecp2, modelo de #Rett desde su etapa pre-sintomática hasta la sintomática

link.springer.com/article/10.1...
Client Challenge
link.springer.com
January 13, 2026 at 9:59 AM
Reposted by Jose Torres
zSwim, the zebrafish lab management software we’ve been developing is now officially listed in Duke OT&C’s technology portfolio! We’re launching an official Duke pilot in March 2026 at the new Ze-Core facility! If you’re in the zebrafish community, check it out!

otc.duke.edu/technologies...
December 11, 2025 at 7:36 PM
Reposted by Jose Torres
Nuestro último estudio está ya disponible on-line.
Hemos estudiado las neuronas “viejóvenes” de la corteza olfativa del ratón, y hemos visto que la falta de Mecp2 les está impidiendo madurar correctamente.
Ojo a los métodos artesanales: para las figuras 2 y 3, Paloma las dibujó a mano, una a una
Doublecortin-expressing cells are selectively altered in the piriform cortex but not in neurogenic areas of symptomatic Mecp2-heterozygous mice
Rett Syndrome (RTT) is a neurodevelopmental disorder which mainly affects girls, leading to profound impairments in motor function, loss of speech, in…
www.sciencedirect.com
December 8, 2025 at 6:23 AM
Reposted by Jose Torres
After a constructive and extensive revision, happy to share our manuscript published in @elife.bsky.social entitled "Dorsal hippocampus mediates light–tone associations in male mice" (doi.org/10.7554/eLif...). Congrats to Julia Pinho, @carlarduaso.bsky.social and @imanzanaressierra.bsky.social.
Dorsal hippocampus mediates light–tone associations in male mice
A light–tone sensory preconditioning task in male mice is developed revealing sex differences and demonstrating that dorsal, but not ventral, hippocampal CaMKII-positive neurons encode innocuous stimu...
doi.org
December 4, 2025 at 9:05 PM
Reposted by Jose Torres
🐟 We’re looking for a zebrafish line similar to Tg(vasa:eGFP) that could potentially be shared with us in the UK. This would greatly support some exciting experiments we have planned. If anyone is able to help or point us in the right direction, we’d be very grateful! 🐟
@zebrafishrock.bsky.social
December 5, 2025 at 1:39 PM
Reposted by Jose Torres
"Fishman", proposal for a journal cover.
Commissioned by MY Dennis' lab @mydennis.bsky.social for a study focused on identifying human-specific gene duplications and their role in brain evolution using genomics and zebrafish as model. @dcsoto.bsky.social
#art #digitalart #sciart #fish
September 25, 2025 at 9:33 AM
🚨 Buscamos técnico/a para solicitar la ayuda PTA 2025 (@AgEInves) en la @uv_es
Proyecto: Pain & Epilepsy in Rett Syndrome: Insights from #Mouse and #Zebrafish
📅 Candidaturas: 8–15/10/2025
📧 maria.abellan@uv.es | jose.vicente.torres@uv.es
#PTA2025 #RettSyndrome #Neurociencia
October 8, 2025 at 5:30 PM
Thrilled to share that our new paper is now available as a pre-proof in Behavioural Brain Research!
👉 doi.org/10.1016/j.bb...
We investigated how genes associated with #WilliamsSyndrome (WS) influence the ability to discriminate #quantities using the #zebrafish model 🐟
Redirecting
doi.org
October 3, 2025 at 8:50 AM
Reposted by Jose Torres
New @maxplanck.de study: We looked for left-right differences of gene expression and cell-type abundances in the brains of MICE 🐭using Xenium @10xgenomics.bsky.social. Possible clues to how functional brain asymmetry is supported !! www.biorxiv.org/content/10.1... Short thread below ⬇️
September 12, 2025 at 7:10 AM
Dr Abellan-Álvaro @mariadoe.bsky.social is doing an amazing job with her poster S02-14 on #Behaviour & #Molecular consequences of #Pesticides exposure on #Zebrafish. Thanks to @SENC_ @JovInvest_SENC for supporting her with a #SENCTravelGrant
September 4, 2025 at 9:46 AM
New paper out! We show #zebrafish exposed to a cocktail of #pesticides during early development display long-lasting neurobehavioral alterations. check it here: doi.org/10.1007/s002...
Done @ccbiologiquesuv.bsky.social‬ (‪@uv.es‬), in collab w/ France & the UK
Zebrafish exposed to a cocktail of pesticides during early development display long-lasting neurobehavioral alterations - Archives of Toxicology
The widespread use of pesticides is increasing the presence of environmental contaminants with potential impacts on biodiversity, ecosystems, and human health. Although long-term pesticide effects hav...
doi.org
August 26, 2025 at 8:50 AM
🎉 Excited to share that we have been awarded a Projecte d’Investigació Emergent grant from Generalitat Valenciana #CIGE! Huge thanks for supporting our research at ‪‪@ccbiologiquesuv.bsky.social‬. More info 👉 www.gva.es/es/inicio/pr... CIGE/2024/73
Subvenciones a grupos de investigación emergentes. GE - GVA.ES - Generalitat Valenciana
www.gva.es
July 25, 2025 at 2:21 PM
Reposted by Jose Torres
A parting gift to stay connected ❤️ 🧪

Starter Packs for #zebrafish Community:

ZF Resources: go.bsky.app/JcC5df3
#WomenInScience V1: go.bsky.app/4BegEjv
#WomenInScience V2: go.bsky.app/VoebYrt
ZF PIs V1: go.bsky.app/2cHYybY
ZF PIs V2: go.bsky.app/4zBuxAF
ZF PIs V3: go.bsky.app/JvjuSZg
June 29, 2025 at 6:42 AM
Reposted by Jose Torres
L’estrès en la infància altera la morfologia de cèl·lules cerebrals del sistema immune en ratolins amb una mutació vinculada a la síndrome de Rett

La micròglia actua com la principal línia de defensa immunitària del cervell i la medul·la espinal.

🔗 www.uv.es/uvweb/uv-not...
June 25, 2025 at 11:18 AM
Reposted by Jose Torres
Thanks Jose for the work!
Step by step, knowing a little bit more about #Mecp2 and the consequences of its loss #Rett
June 17, 2025 at 12:16 PM
🧠 New research out in NeuroMolecular Medicine: We show that early-life stress disrupts #microglia adaptability in the periaqueductal grey of #Mecp2-heterozygous mice before symptom onset. doi.org/10.1007/s120...
Thanks to @mariadoe.bsky.social, @carmenagustin.bsky.social and the rest not here! #Rett
Altered Microglial Plasticity in the Periaqueductal Grey of Pre-Symptomatic Mecp2-Heterozygous Mice Following Early-Life Stress - NeuroMolecular Medicine
Rett syndrome (RTT), a severe neurodevelopmental disorder primarily affecting girls, is commonly caused by MECP2 loss-of-function mutations. Key symptoms include motor impairments, typical hand stereo...
doi.org
June 17, 2025 at 11:59 AM
Reposted by Jose Torres
Our latest paper is finally on-line: we found that immature neurons in the piriform cortex follow an anteroposterior gradient of maturation with age, but are not significantly affected by motherhood. First paper of the PhD Thesis of Rafa Esteve!

link.springer.com/article/10.1...
The density of doublecortin cells in the piriform cortex is affected by transition to adulthood but not first pregnancy in mice - Brain Structure and Function
Brain Structure and Function - Motherhood is a critical period modulating behavioural changes to favour survival in mammals. In mice, olfaction is a key driver of social behaviours, and adult...
link.springer.com
June 10, 2025 at 1:16 PM