Joe Matthews
@josephmatthews.bsky.social
Postdoctoral Research Fellow at the University of Arkansas for Medical Sciences (UAMS). Physiologist and Nutritionist - 🇬🇧🇮🇳
Two interesting metabolic health studies published this month!
👉🏽 Effect of sweeteners on weight management and gut microbiota composition in individuals with overweight or obesity: the SWEET study
🔘 ~1.6 kg improvement in across all participants
🔘 ~3.8 kg improvement in the highest adherence group
👉🏽 Effect of sweeteners on weight management and gut microbiota composition in individuals with overweight or obesity: the SWEET study
🔘 ~1.6 kg improvement in across all participants
🔘 ~3.8 kg improvement in the highest adherence group
October 27, 2025 at 4:31 PM
Two interesting metabolic health studies published this month!
👉🏽 Effect of sweeteners on weight management and gut microbiota composition in individuals with overweight or obesity: the SWEET study
🔘 ~1.6 kg improvement in across all participants
🔘 ~3.8 kg improvement in the highest adherence group
👉🏽 Effect of sweeteners on weight management and gut microbiota composition in individuals with overweight or obesity: the SWEET study
🔘 ~1.6 kg improvement in across all participants
🔘 ~3.8 kg improvement in the highest adherence group
Okay I’m officially done on X/Twitter. In dire need of a healthy science community with people posting interesting takes on research. Where are my nutrition and metabolism people…? 🍎
a man drinking from a can that says science on it
ALT: a man drinking from a can that says science on it
media.tenor.com
October 3, 2025 at 6:52 PM
Okay I’m officially done on X/Twitter. In dire need of a healthy science community with people posting interesting takes on research. Where are my nutrition and metabolism people…? 🍎
In my latest Substack, I cover the science of how biology fights back after weight loss:
🔘 Metabolic adaptation (or not…)
🔘 Hunger hormone shifts
🔘 Heightened reward sensitivity to food cues
🔘 A potential “memory” of obesity in fat cells
🔗 josephmatthewsphd.substack.com/p/the-bigges...
🔘 Metabolic adaptation (or not…)
🔘 Hunger hormone shifts
🔘 Heightened reward sensitivity to food cues
🔘 A potential “memory” of obesity in fat cells
🔗 josephmatthewsphd.substack.com/p/the-bigges...
October 2, 2025 at 12:30 PM
In my latest Substack, I cover the science of how biology fights back after weight loss:
🔘 Metabolic adaptation (or not…)
🔘 Hunger hormone shifts
🔘 Heightened reward sensitivity to food cues
🔘 A potential “memory” of obesity in fat cells
🔗 josephmatthewsphd.substack.com/p/the-bigges...
🔘 Metabolic adaptation (or not…)
🔘 Hunger hormone shifts
🔘 Heightened reward sensitivity to food cues
🔘 A potential “memory” of obesity in fat cells
🔗 josephmatthewsphd.substack.com/p/the-bigges...
What is dietary protein quality?
New paper in the Journal of Nutrition. My first, first-author paper since joining UAMS.
Dietary protein quality is the ability of a protein source to provide bioavailable essential amino acids (EAAs). But what affects this…?👇🏽
🔗 shorturl.at/elQLE
New paper in the Journal of Nutrition. My first, first-author paper since joining UAMS.
Dietary protein quality is the ability of a protein source to provide bioavailable essential amino acids (EAAs). But what affects this…?👇🏽
🔗 shorturl.at/elQLE
July 20, 2025 at 8:54 PM
What is dietary protein quality?
New paper in the Journal of Nutrition. My first, first-author paper since joining UAMS.
Dietary protein quality is the ability of a protein source to provide bioavailable essential amino acids (EAAs). But what affects this…?👇🏽
🔗 shorturl.at/elQLE
New paper in the Journal of Nutrition. My first, first-author paper since joining UAMS.
Dietary protein quality is the ability of a protein source to provide bioavailable essential amino acids (EAAs). But what affects this…?👇🏽
🔗 shorturl.at/elQLE
One year in Little Rock, Arkansas! 🇺🇸
It's hard to believe a year has passed already. Looking forward to spending more time in The Natural State!
It's hard to believe a year has passed already. Looking forward to spending more time in The Natural State!
July 4, 2025 at 5:36 PM
One year in Little Rock, Arkansas! 🇺🇸
It's hard to believe a year has passed already. Looking forward to spending more time in The Natural State!
It's hard to believe a year has passed already. Looking forward to spending more time in The Natural State!
Reposted by Joe Matthews
🚨 New study 🚨
The biggest project of my PhD is out in MSSE journal.
🔑 findings: Strength training improves running economy durability & high-intensity performance following prolonged running.
🙏🏼 R. Blagrove and J. Folland for the SUPERvision on this.
🔗 journals.lww.com/acsm-msse/ab...
🧵 1/10
The biggest project of my PhD is out in MSSE journal.
🔑 findings: Strength training improves running economy durability & high-intensity performance following prolonged running.
🙏🏼 R. Blagrove and J. Folland for the SUPERvision on this.
🔗 journals.lww.com/acsm-msse/ab...
🧵 1/10
March 2, 2025 at 7:06 PM
🚨 New study 🚨
The biggest project of my PhD is out in MSSE journal.
🔑 findings: Strength training improves running economy durability & high-intensity performance following prolonged running.
🙏🏼 R. Blagrove and J. Folland for the SUPERvision on this.
🔗 journals.lww.com/acsm-msse/ab...
🧵 1/10
The biggest project of my PhD is out in MSSE journal.
🔑 findings: Strength training improves running economy durability & high-intensity performance following prolonged running.
🙏🏼 R. Blagrove and J. Folland for the SUPERvision on this.
🔗 journals.lww.com/acsm-msse/ab...
🧵 1/10
Do carnosine and beta-alanine (BA) offer benefits beyond enhancing exercise performance?
Yes and no 🤔
📰 Thread with summary of research and links to open-access papers 👇🏽
Yes and no 🤔
📰 Thread with summary of research and links to open-access papers 👇🏽
March 2, 2025 at 6:10 PM
Do carnosine and beta-alanine (BA) offer benefits beyond enhancing exercise performance?
Yes and no 🤔
📰 Thread with summary of research and links to open-access papers 👇🏽
Yes and no 🤔
📰 Thread with summary of research and links to open-access papers 👇🏽
Reposted by Joe Matthews
Christopher W. Sundberg et al. investigated the cumulative effects of H+ and Pi on #force and #power of skeletal muscle fibres from young and older adults 💥🔋
📜 Read the #Research here: https://buff.ly/40BBX02
📜 Read the #Research here: https://buff.ly/40BBX02
January 17, 2025 at 2:00 PM
Christopher W. Sundberg et al. investigated the cumulative effects of H+ and Pi on #force and #power of skeletal muscle fibres from young and older adults 💥🔋
📜 Read the #Research here: https://buff.ly/40BBX02
📜 Read the #Research here: https://buff.ly/40BBX02
The latest publication from our lab at UAMS 👇🏼
A protein intake of 1.5 g/kg/day enhances net protein balance in older adults on a two-meal eating pattern.
by Church DD, Hirsch KR (...) Ferrando AA et 5 al. in J Nutr #MedSky
📖 read the article:
by Church DD, Hirsch KR (...) Ferrando AA et 5 al. in J Nutr #MedSky
📖 read the article:
Effect of Three Different Daily Protein Intakes in a Two-Meal Eating Pattern on Protein Turnover in Middle Age and Older Adults: A Randomized Controlled Trial
Reduced meal frequency patterns have become popular for weight loss, maintenance, and improving cardiometabolic health. The extended fasting windows w…
www.sciencedirect.com
January 8, 2025 at 11:57 PM
The latest publication from our lab at UAMS 👇🏼
2024 Protein Nutrition Review!
What's new in dietary protein? 🥩🫘
A brief overview of SEVEN insightful muscle protein synthesis (MPS) studies (references and links included) 👇🏽
What's new in dietary protein? 🥩🫘
A brief overview of SEVEN insightful muscle protein synthesis (MPS) studies (references and links included) 👇🏽
January 4, 2025 at 11:55 AM
2024 Protein Nutrition Review!
What's new in dietary protein? 🥩🫘
A brief overview of SEVEN insightful muscle protein synthesis (MPS) studies (references and links included) 👇🏽
What's new in dietary protein? 🥩🫘
A brief overview of SEVEN insightful muscle protein synthesis (MPS) studies (references and links included) 👇🏽
New study suggests a higher plant-to-animal protein ratio is associated with lower risks of CVD and CAD.
I find these studies challenging to interpret given the underlying data used in the analyses:
"A food frequency questionnaire was administered every 4 years to determine dietary intake"
I find these studies challenging to interpret given the underlying data used in the analyses:
"A food frequency questionnaire was administered every 4 years to determine dietary intake"
December 27, 2024 at 3:16 PM
New study suggests a higher plant-to-animal protein ratio is associated with lower risks of CVD and CAD.
I find these studies challenging to interpret given the underlying data used in the analyses:
"A food frequency questionnaire was administered every 4 years to determine dietary intake"
I find these studies challenging to interpret given the underlying data used in the analyses:
"A food frequency questionnaire was administered every 4 years to determine dietary intake"
“Cellular engineering has already allowed us to rebuild parts of humans with re-engineered cells. As our understanding of this arena grows, new medical and ethical conundrums will arise, intensifying and challenging the basic definition of who we are, and how much we wish to change ourselves.”
Finally finished this masterpiece from @DrSidMukherjee - a beautiful story on the past, present, and future of cell biology and its role in health and disease 🦠🧬🧫
December 2, 2024 at 2:00 PM
“Cellular engineering has already allowed us to rebuild parts of humans with re-engineered cells. As our understanding of this arena grows, new medical and ethical conundrums will arise, intensifying and challenging the basic definition of who we are, and how much we wish to change ourselves.”
Finally finished this masterpiece from @DrSidMukherjee - a beautiful story on the past, present, and future of cell biology and its role in health and disease 🦠🧬🧫
December 2, 2024 at 1:59 PM
Finally finished this masterpiece from @DrSidMukherjee - a beautiful story on the past, present, and future of cell biology and its role in health and disease 🦠🧬🧫
Happy Thanksgiving to all my friends in the US! 🦃
November 28, 2024 at 2:32 PM
Happy Thanksgiving to all my friends in the US! 🦃
Biomedical researchers share their priorities for the U.S. ahead of incoming administration:
⚪ Support education and reproductive care
⚪ Embrance medical AI
⚪ Protect patients
⚪ Prepare for the next pandemic
⚪ Be smarter with antibiotics
www.nature.com/articles/d41...
⚪ Support education and reproductive care
⚪ Embrance medical AI
⚪ Protect patients
⚪ Prepare for the next pandemic
⚪ Be smarter with antibiotics
www.nature.com/articles/d41...
Hopes, fears and uncertainty: life scientists react to Trump’s election victory
Leading biomedical researchers outline their priorities for the incoming administration.
www.nature.com
November 27, 2024 at 4:07 PM
Biomedical researchers share their priorities for the U.S. ahead of incoming administration:
⚪ Support education and reproductive care
⚪ Embrance medical AI
⚪ Protect patients
⚪ Prepare for the next pandemic
⚪ Be smarter with antibiotics
www.nature.com/articles/d41...
⚪ Support education and reproductive care
⚪ Embrance medical AI
⚪ Protect patients
⚪ Prepare for the next pandemic
⚪ Be smarter with antibiotics
www.nature.com/articles/d41...
Hugely relatable scene in the new film Joy on Netflix
November 27, 2024 at 3:34 PM
Hugely relatable scene in the new film Joy on Netflix
Helpful 2-minute primer on Mendelian randomization: www.youtube.com/watch?v=LoTg...
A two minute primer on mendelian randomisation
YouTube video by TARG Bristol
www.youtube.com
November 24, 2024 at 3:44 PM
Helpful 2-minute primer on Mendelian randomization: www.youtube.com/watch?v=LoTg...
Two great lectures on Mendelian randomization and evidence triangulation by @mendelrandom.bsky.social - thanks to @bennettoxford.bsky.social for making these publicly available!
www.bennett.ox.ac.uk/blog/2024/10...
www.bennett.ox.ac.uk/blog/2024/10...
Thank you, George | Bennett Institute for Applied Data Science
Thanks to George Davey Smith for his inspiring visit to the Bennett Institute.
www.bennett.ox.ac.uk
November 24, 2024 at 3:40 PM
Two great lectures on Mendelian randomization and evidence triangulation by @mendelrandom.bsky.social - thanks to @bennettoxford.bsky.social for making these publicly available!
www.bennett.ox.ac.uk/blog/2024/10...
www.bennett.ox.ac.uk/blog/2024/10...
Beautiful 🤌🏽
Today’s poem is called ‘The Importance of the Oxford Comma’.
November 23, 2024 at 7:05 PM
Beautiful 🤌🏽
The Consensus app is a game-changer for scientific searches and writing. It generates research summaries and links to peer-reviewed articles (also available as an app via Chat GPT) 👇🏽
November 21, 2024 at 4:18 PM
The Consensus app is a game-changer for scientific searches and writing. It generates research summaries and links to peer-reviewed articles (also available as an app via Chat GPT) 👇🏽
Reposted by Joe Matthews
Views about the causes of obesity have polarised. Characterised by low carb and energy balance models. Last year NovoNordisk invited the protagonists of these models to Copenhagen to discuss commonalities and differences. The resultant paper has now been published in Nature Metabolism rdcu.be/dZryb
On the pathogenesis of obesity: causal models and missing pieces of the puzzle
Nature Metabolism - This authoritative Perspective lays a foundation for the field of obesity research by comparing commonalities and differences between competing models of obesity pathogenesis...
rdcu.be
November 21, 2024 at 1:23 PM
Views about the causes of obesity have polarised. Characterised by low carb and energy balance models. Last year NovoNordisk invited the protagonists of these models to Copenhagen to discuss commonalities and differences. The resultant paper has now been published in Nature Metabolism rdcu.be/dZryb
Irony intensifies: a story in three parts.
November 21, 2024 at 1:04 PM
Irony intensifies: a story in three parts.
Reposted by Joe Matthews
Left, a non-randomized study showing that saunas significantly decrease arterial stiffness.
Right, a randomized, crossover study, showing no benefits on arterial stiffness/blood flow. Note the colossal difference in media attention.
In the media, sensational studies > robust ones.
#science #media
Right, a randomized, crossover study, showing no benefits on arterial stiffness/blood flow. Note the colossal difference in media attention.
In the media, sensational studies > robust ones.
#science #media
November 19, 2024 at 4:31 PM