Jonas Neher
@jonasneher.bsky.social
Neuroscientist, focus on neuroinflammation and amyloid, @LMU_Muenchen, @DZNE_en, @LMU_BMC and @SyNergy_Cluster
www.neher-lab.de
www.neher-lab.de
Important study for understanding the vascular mechanisms of dementia!
🚨 NEW PUBLICATION 🚨 "Human brain vascular multi-omics elucidates disease-risk associations"
www.cell.com/neuron/abstr...
@ucsanfrancisco.bsky.social
@madiganreid.bsky.social
@cellpress.bsky.social
www.cell.com/neuron/abstr...
@ucsanfrancisco.bsky.social
@madiganreid.bsky.social
@cellpress.bsky.social
Human brain vascular multi-omics elucidates disease-risk associations
Reid et al. develop MultiVINE-seq to map thousands of non-coding disease variants
to genes in human brain vascular cells. Cerebrovascular disease variants compromise
vessel integrity, whereas Alzheime...
www.cell.com
August 21, 2025 at 6:23 AM
Important study for understanding the vascular mechanisms of dementia!
Very cool work! Glad to have been able to contribute.
🔬 New Preprint on bioRxiv!
📄 "Medin drives Aβ40 to adopt Aβ42‑like fibril polymorphs in vitro"
🧠 Alzheimer’s | 🧩 Amyloids | 🧬 Cryo-EM
I'm thrilled to share our latest Cryo-EM work, which shows how medin, a vascular amyloid, reshapes Aβ40 fibrils to mimic the more toxic Aβ42 polymorphs.
📄 "Medin drives Aβ40 to adopt Aβ42‑like fibril polymorphs in vitro"
🧠 Alzheimer’s | 🧩 Amyloids | 🧬 Cryo-EM
I'm thrilled to share our latest Cryo-EM work, which shows how medin, a vascular amyloid, reshapes Aβ40 fibrils to mimic the more toxic Aβ42 polymorphs.
July 26, 2025 at 12:58 PM
Very cool work! Glad to have been able to contribute.
Reposted by Jonas Neher
Good times discussing all things #epigenetics and #microglia at our symposium with this awesome group: @jonasneher.bsky.social, @kooistrasm.bsky.social, @mancusorenzo.bsky.social. And enjoying the sun and science at #glia2025 in Marseille, while hoping that fires can be contained.
July 10, 2025 at 12:29 PM
Good times discussing all things #epigenetics and #microglia at our symposium with this awesome group: @jonasneher.bsky.social, @kooistrasm.bsky.social, @mancusorenzo.bsky.social. And enjoying the sun and science at #glia2025 in Marseille, while hoping that fires can be contained.
Reposted by Jonas Neher
it's big, and it's a review of 601 papers on the topic - but here's an update on Neuroinflammation in Alzheimer's Disease
www.nature.com/articles/s41...
led by Michael Heneka, published in @natrevimmunol.bsky.social today
(MANY more authors listed and linked below)
www.nature.com/articles/s41...
led by Michael Heneka, published in @natrevimmunol.bsky.social today
(MANY more authors listed and linked below)
Neuroinflammation in Alzheimer disease - Nature Reviews Immunology
This Review provides an in-depth examination of how inflammation contributes to neurodegeneration in Alzheimer disease. The authors explore the impact of extrinsic factors, such as brain trauma, diet ...
www.nature.com
December 10, 2024 at 3:03 AM
it's big, and it's a review of 601 papers on the topic - but here's an update on Neuroinflammation in Alzheimer's Disease
www.nature.com/articles/s41...
led by Michael Heneka, published in @natrevimmunol.bsky.social today
(MANY more authors listed and linked below)
www.nature.com/articles/s41...
led by Michael Heneka, published in @natrevimmunol.bsky.social today
(MANY more authors listed and linked below)