Jim Januzzi
@jimjanuzzi.bsky.social
Formerly known as @JJHeart_Doc on the "bird" app.
Professor of Medicine, Harvard; Cardiologist, MGH; Chief Scientific Officer, Baim Institute; Deputy Editor, JACC. Team MD for the Boston Red Sox.
I used to be disgusted. Now I try to be amused.
Professor of Medicine, Harvard; Cardiologist, MGH; Chief Scientific Officer, Baim Institute; Deputy Editor, JACC. Team MD for the Boston Red Sox.
I used to be disgusted. Now I try to be amused.
Reposted by Jim Januzzi
“Philanthropy can lead to some really remarkable changes in how leadership can be cultivated, research can be distributed and health care can be improved.” 🗣️ ACC Philanthropic Fundraising Committee Chair Dr. @jimjanuzzi.bsky.social
📽️ https://bit.ly/4qQrkBv #ACCPresident @chriskramermd.bsky.social
📽️ https://bit.ly/4qQrkBv #ACCPresident @chriskramermd.bsky.social
November 11, 2025 at 5:40 PM
“Philanthropy can lead to some really remarkable changes in how leadership can be cultivated, research can be distributed and health care can be improved.” 🗣️ ACC Philanthropic Fundraising Committee Chair Dr. @jimjanuzzi.bsky.social
📽️ https://bit.ly/4qQrkBv #ACCPresident @chriskramermd.bsky.social
📽️ https://bit.ly/4qQrkBv #ACCPresident @chriskramermd.bsky.social
I don't post much anymore, but I felt it worth reminding our colleagues that "follow up with your cardiologist ASAP" is not a guideline supported move nor a therapeutic intervention for someone discharged with ongoing new onset atrial flutter with RVR on a Friday afternoon.
#cardiosky
#cardiosky
October 31, 2025 at 8:04 PM
I don't post much anymore, but I felt it worth reminding our colleagues that "follow up with your cardiologist ASAP" is not a guideline supported move nor a therapeutic intervention for someone discharged with ongoing new onset atrial flutter with RVR on a Friday afternoon.
#cardiosky
#cardiosky
Reposted by Jim Januzzi
Selective in vitro enhancement of cardiac myosin motor function and myofilament force generation by danicamtiv prompted clinical evaluation. A short course of danicamtiv was generally well tolerated in participants with #DCM https://bit.ly/4mE3vcM
#HFSA2025 #JACC #cvGenetics @jimjanuzzi.bsky.social
#HFSA2025 #JACC #cvGenetics @jimjanuzzi.bsky.social
September 29, 2025 at 3:33 PM
Selective in vitro enhancement of cardiac myosin motor function and myofilament force generation by danicamtiv prompted clinical evaluation. A short course of danicamtiv was generally well tolerated in participants with #DCM https://bit.ly/4mE3vcM
#HFSA2025 #JACC #cvGenetics @jimjanuzzi.bsky.social
#HFSA2025 #JACC #cvGenetics @jimjanuzzi.bsky.social
Reposted by Jim Januzzi
Short & sweet! Check out our review of #SGLT2i & #GLP1RA in #HeartFailure! Great work Jose Lopez & team! @ucsfcardiology.bsky.social @amitgoyalmd.bsky.social @robmentz.bsky.social @dranulala.bsky.social @jimjanuzzi.bsky.social @sjgreene-md.bsky.social
www.uscjournal.com/articles/sho...
www.uscjournal.com/articles/sho...
The Short and Sweet on Sodium–Glucose Cotransporter Inhibitors and Glucagon-like Peptide-1 Receptor Agonists in Heart Failure
Heart failure (HF) affects 6 million people in the US, and type 2 diabetes (T2D) is a significant risk factor for HF. Since 2008, regulatory agencies have required cardiovascular safety trials
www.uscjournal.com
May 13, 2025 at 11:14 PM
Short & sweet! Check out our review of #SGLT2i & #GLP1RA in #HeartFailure! Great work Jose Lopez & team! @ucsfcardiology.bsky.social @amitgoyalmd.bsky.social @robmentz.bsky.social @dranulala.bsky.social @jimjanuzzi.bsky.social @sjgreene-md.bsky.social
www.uscjournal.com/articles/sho...
www.uscjournal.com/articles/sho...
Reposted by Jim Januzzi
Great presentation by @jimjanuzzi.bsky.social at #ACCAsia in Singapore on optimizing decongestion using diuretics and GDMT in patients with HF. Access more HF resources in the @accintouch.bsky.social Guidelines Hub: acc.org/guidelines
May 10, 2025 at 1:20 AM
Great presentation by @jimjanuzzi.bsky.social at #ACCAsia in Singapore on optimizing decongestion using diuretics and GDMT in patients with HF. Access more HF resources in the @accintouch.bsky.social Guidelines Hub: acc.org/guidelines
Reposted by Jim Januzzi
Get to Know Your Leaders | Leading With Purpose:
Meet Chris Kramer, MD, FACC
@chriskramermd.bsky.social
#CardiologyMagazine
#CardioSky
www.acc.org/Latest-in-Ca...
@accintouch.bsky.social @jaccjournals.bsky.social @jimjanuzzi.bsky.social @drmarthagulati.bsky.social @vietheartpa.bsky.social
Meet Chris Kramer, MD, FACC
@chriskramermd.bsky.social
#CardiologyMagazine
#CardioSky
www.acc.org/Latest-in-Ca...
@accintouch.bsky.social @jaccjournals.bsky.social @jimjanuzzi.bsky.social @drmarthagulati.bsky.social @vietheartpa.bsky.social
May 6, 2025 at 10:25 PM
Get to Know Your Leaders | Leading With Purpose:
Meet Chris Kramer, MD, FACC
@chriskramermd.bsky.social
#CardiologyMagazine
#CardioSky
www.acc.org/Latest-in-Ca...
@accintouch.bsky.social @jaccjournals.bsky.social @jimjanuzzi.bsky.social @drmarthagulati.bsky.social @vietheartpa.bsky.social
Meet Chris Kramer, MD, FACC
@chriskramermd.bsky.social
#CardiologyMagazine
#CardioSky
www.acc.org/Latest-in-Ca...
@accintouch.bsky.social @jaccjournals.bsky.social @jimjanuzzi.bsky.social @drmarthagulati.bsky.social @vietheartpa.bsky.social
The weekend cannot come fast enough.
April 17, 2025 at 8:09 PM
The weekend cannot come fast enough.
Reposted by Jim Januzzi
Hope for tx of nHCM:
According to the company, this partial fatty acid oxidation (pFOX) inhibitor is an oral compound that promotes a shift in the heart’s preference from fatty acids to glucose, resulting in energy generation by the mitochondria.
#HCM #CardioSky #Cardiomyopathy #Cardiology
According to the company, this partial fatty acid oxidation (pFOX) inhibitor is an oral compound that promotes a shift in the heart’s preference from fatty acids to glucose, resulting in energy generation by the mitochondria.
#HCM #CardioSky #Cardiomyopathy #Cardiology
Imbria secures $57.5m to advance ninerafaxstat through Phase IIb trial
Imbria has secured $57.5m in a Series B funding round to support the progression of ninerafaxstat through a Phase IIb trial in nHCM.
www.pharmaceutical-business-review.com
April 16, 2025 at 7:00 PM
Hope for tx of nHCM:
According to the company, this partial fatty acid oxidation (pFOX) inhibitor is an oral compound that promotes a shift in the heart’s preference from fatty acids to glucose, resulting in energy generation by the mitochondria.
#HCM #CardioSky #Cardiomyopathy #Cardiology
According to the company, this partial fatty acid oxidation (pFOX) inhibitor is an oral compound that promotes a shift in the heart’s preference from fatty acids to glucose, resulting in energy generation by the mitochondria.
#HCM #CardioSky #Cardiomyopathy #Cardiology
Reposted by Jim Januzzi
Clinical and plasma proteomic characterization of heart failure with supranormal left ventricular ejection fraction: An emerging entity of heart failure
#EJHF @escardio.bsky.social
#CardioSky @shelleyzieroth.bsky.social @jimjanuzzi.bsky.social @drmarthagulati.bsky.social @cardioobdoc.bsky.social
#EJHF @escardio.bsky.social
#CardioSky @shelleyzieroth.bsky.social @jimjanuzzi.bsky.social @drmarthagulati.bsky.social @cardioobdoc.bsky.social
April 15, 2025 at 10:00 PM
Clinical and plasma proteomic characterization of heart failure with supranormal left ventricular ejection fraction: An emerging entity of heart failure
#EJHF @escardio.bsky.social
#CardioSky @shelleyzieroth.bsky.social @jimjanuzzi.bsky.social @drmarthagulati.bsky.social @cardioobdoc.bsky.social
#EJHF @escardio.bsky.social
#CardioSky @shelleyzieroth.bsky.social @jimjanuzzi.bsky.social @drmarthagulati.bsky.social @cardioobdoc.bsky.social
April 3, 2025 at 12:05 AM
I am so incredibly grateful to the @accintouch.bsky.social for the honor of being named the 2025 Distinguished Clinical Researcher.
I am blessed to have stood on the shoulders of giants during my career and am thankful to @mgbresearch.bsky.social and #BaimInstitute for support.
I am blessed to have stood on the shoulders of giants during my career and am thankful to @mgbresearch.bsky.social and #BaimInstitute for support.
April 1, 2025 at 1:37 PM
I am so incredibly grateful to the @accintouch.bsky.social for the honor of being named the 2025 Distinguished Clinical Researcher.
I am blessed to have stood on the shoulders of giants during my career and am thankful to @mgbresearch.bsky.social and #BaimInstitute for support.
I am blessed to have stood on the shoulders of giants during my career and am thankful to @mgbresearch.bsky.social and #BaimInstitute for support.
Reposted by Jim Januzzi
Congratulations @jimjanuzzi.bsky.social
Very well deserved 👏👏
Very well deserved 👏👏
Congratulations @jimjanuzzi.bsky.social on your @accintouch.bsky.social Distinguished Scientist Award!! #ACC25
April 1, 2025 at 3:33 AM
Congratulations @jimjanuzzi.bsky.social
Very well deserved 👏👏
Very well deserved 👏👏
Reposted by Jim Januzzi
Congratulations @jimjanuzzi.bsky.social on your @accintouch.bsky.social Distinguished Scientist Award!! #ACC25
April 1, 2025 at 12:43 AM
Congratulations @jimjanuzzi.bsky.social on your @accintouch.bsky.social Distinguished Scientist Award!! #ACC25
Reposted by Jim Januzzi
Congratulations to new #ACCPresident Christopher M. Kramer, MD, FACC! Inspired by a movie classic, he shared: “Today I want to talk to you about two Fantastic Voyage-Related themes: innovation and mentorship.”
💬 bit.ly/41RJlF6 @ChrisKramerMD #ACC25 #ACCLeadership
💬 bit.ly/41RJlF6 @ChrisKramerMD #ACC25 #ACCLeadership
March 31, 2025 at 10:15 PM
Congratulations to new #ACCPresident Christopher M. Kramer, MD, FACC! Inspired by a movie classic, he shared: “Today I want to talk to you about two Fantastic Voyage-Related themes: innovation and mentorship.”
💬 bit.ly/41RJlF6 @ChrisKramerMD #ACC25 #ACCLeadership
💬 bit.ly/41RJlF6 @ChrisKramerMD #ACC25 #ACCLeadership
Reposted by Jim Januzzi
FRESH-UP Trial #ACC25 #medsky
RCT comparing liberal vs restricted fluid intake (≤1500 ml/d) in 504 pts with stable chronic HF
🌊No difference in status health quantified by Kansas City Cardiomyopathy Questionnaire at 3 mths
🌊 More thirst distress with restriction
www.nature.com/articles/s41...
RCT comparing liberal vs restricted fluid intake (≤1500 ml/d) in 504 pts with stable chronic HF
🌊No difference in status health quantified by Kansas City Cardiomyopathy Questionnaire at 3 mths
🌊 More thirst distress with restriction
www.nature.com/articles/s41...
March 30, 2025 at 8:50 PM
FRESH-UP Trial #ACC25 #medsky
RCT comparing liberal vs restricted fluid intake (≤1500 ml/d) in 504 pts with stable chronic HF
🌊No difference in status health quantified by Kansas City Cardiomyopathy Questionnaire at 3 mths
🌊 More thirst distress with restriction
www.nature.com/articles/s41...
RCT comparing liberal vs restricted fluid intake (≤1500 ml/d) in 504 pts with stable chronic HF
🌊No difference in status health quantified by Kansas City Cardiomyopathy Questionnaire at 3 mths
🌊 More thirst distress with restriction
www.nature.com/articles/s41...
Reposted by Jim Januzzi
Fluid restriction associated with trend to worse QoL and greater thirst in stable outpatients with HF. No difference in safety.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Liberal fluid intake versus fluid restriction in chronic heart failure: a randomized clinical trial - Nature Medicine
While fluid restriction is typically recommended for patients with chronic heart failure, this randomized clinical trial showed no difference in health status, as assessed by patient-reported outcomes...
www.nature.com
March 31, 2025 at 5:37 AM
Fluid restriction associated with trend to worse QoL and greater thirst in stable outpatients with HF. No difference in safety.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Jim Januzzi
Terrific @accintouch.bsky.social @acc25 session on the intersection of heart failure and imaging. Great job @purviparwani.bsky.social @michaelsalerno.bsky.social moderating the interesting case-based discussions @jimjanuzzi.bsky.social
March 30, 2025 at 5:11 PM
Terrific @accintouch.bsky.social @acc25 session on the intersection of heart failure and imaging. Great job @purviparwani.bsky.social @michaelsalerno.bsky.social moderating the interesting case-based discussions @jimjanuzzi.bsky.social
March 27, 2025 at 4:37 PM
Happy birthday to a person who makes the world more beautiful.
Walking the beach where just a few months ago our buddy was having the time of his life. Glad to share the moment together.
There are blue skies beyond this.
Happiest of birthdays, RSJ.
@robertasensen.bsky.social
Walking the beach where just a few months ago our buddy was having the time of his life. Glad to share the moment together.
There are blue skies beyond this.
Happiest of birthdays, RSJ.
@robertasensen.bsky.social
March 24, 2025 at 9:18 PM
Happy birthday to a person who makes the world more beautiful.
Walking the beach where just a few months ago our buddy was having the time of his life. Glad to share the moment together.
There are blue skies beyond this.
Happiest of birthdays, RSJ.
@robertasensen.bsky.social
Walking the beach where just a few months ago our buddy was having the time of his life. Glad to share the moment together.
There are blue skies beyond this.
Happiest of birthdays, RSJ.
@robertasensen.bsky.social
I did not have habitually watching eaglets on my 2025 bingo card but we are completely here for #JackieandShadow and their babies.
#FOBBV #eagles @robertasensen.bsky.social
#FOBBV #eagles @robertasensen.bsky.social
March 22, 2025 at 1:29 PM
I did not have habitually watching eaglets on my 2025 bingo card but we are completely here for #JackieandShadow and their babies.
#FOBBV #eagles @robertasensen.bsky.social
#FOBBV #eagles @robertasensen.bsky.social
Enough is enough.
I have deleted my Twitter account.
Not worth it anymore.
I have deleted my Twitter account.
Not worth it anymore.
March 19, 2025 at 9:36 PM
Enough is enough.
I have deleted my Twitter account.
Not worth it anymore.
I have deleted my Twitter account.
Not worth it anymore.
Courtside @thebostonceltics.bsky.social with @robertasensen.bsky.social and the fam.
March 3, 2025 at 12:51 PM
Courtside @thebostonceltics.bsky.social with @robertasensen.bsky.social and the fam.
Reposted by Jim Januzzi
In pts undergoing 99mTc PYP imaging for suspected #ATTR, hs-cTnT & NT-proBNP can effectively rule out diagnosis, although in a small subset of patients
#CardioSky
www.jacc.org/doi/10.1016/...
@jaccjournals.bsky.social @vietheartpa.bsky.social @load-dependent.bsky.social @jimjanuzzi.bsky.social
#CardioSky
www.jacc.org/doi/10.1016/...
@jaccjournals.bsky.social @vietheartpa.bsky.social @load-dependent.bsky.social @jimjanuzzi.bsky.social
February 19, 2025 at 2:06 AM
In pts undergoing 99mTc PYP imaging for suspected #ATTR, hs-cTnT & NT-proBNP can effectively rule out diagnosis, although in a small subset of patients
#CardioSky
www.jacc.org/doi/10.1016/...
@jaccjournals.bsky.social @vietheartpa.bsky.social @load-dependent.bsky.social @jimjanuzzi.bsky.social
#CardioSky
www.jacc.org/doi/10.1016/...
@jaccjournals.bsky.social @vietheartpa.bsky.social @load-dependent.bsky.social @jimjanuzzi.bsky.social
Game time, Courtside with @julijanuzzi.bsky.social @thebostonceltics.bsky.social
January 12, 2025 at 11:01 PM
Game time, Courtside with @julijanuzzi.bsky.social @thebostonceltics.bsky.social