Jiménez-Ruiz Lab
@jimenezruizlab.bsky.social
Parasitologist @ LMU Munich | Chair of Experimental Parasitology | Exploring non-histone methylation in Toxoplasma gondii and beyond | #Methylation #Parasitology #MolecularBiology
Pinned
Dual apical methyltransferases orchestrate motility initiation in apicomplexan parasites https://www.biorxiv.org/content/10.1101/2025.11.05.686696v1
New on bioRxiv!
Our manuscript shows how the methyltransferase PCKMT primes the conoid by retaining Formin1 for motility initiation in Toxoplasma gondii, working with AKMT to activate the parasite’s motility machinery.
#Toxoplasma #Apicomplexa #Methylation #ParasiteMotility
Our manuscript shows how the methyltransferase PCKMT primes the conoid by retaining Formin1 for motility initiation in Toxoplasma gondii, working with AKMT to activate the parasite’s motility machinery.
#Toxoplasma #Apicomplexa #Methylation #ParasiteMotility
New on bioRxiv!
Our manuscript shows how the methyltransferase PCKMT primes the conoid by retaining Formin1 for motility initiation in Toxoplasma gondii, working with AKMT to activate the parasite’s motility machinery.
#Toxoplasma #Apicomplexa #Methylation #ParasiteMotility
Our manuscript shows how the methyltransferase PCKMT primes the conoid by retaining Formin1 for motility initiation in Toxoplasma gondii, working with AKMT to activate the parasite’s motility machinery.
#Toxoplasma #Apicomplexa #Methylation #ParasiteMotility
Dual apical methyltransferases orchestrate motility initiation in apicomplexan parasites https://www.biorxiv.org/content/10.1101/2025.11.05.686696v1
November 7, 2025 at 5:44 AM
New on bioRxiv!
Our manuscript shows how the methyltransferase PCKMT primes the conoid by retaining Formin1 for motility initiation in Toxoplasma gondii, working with AKMT to activate the parasite’s motility machinery.
#Toxoplasma #Apicomplexa #Methylation #ParasiteMotility
Our manuscript shows how the methyltransferase PCKMT primes the conoid by retaining Formin1 for motility initiation in Toxoplasma gondii, working with AKMT to activate the parasite’s motility machinery.
#Toxoplasma #Apicomplexa #Methylation #ParasiteMotility
Reposted by Jiménez-Ruiz Lab
See companion study from Grech et al. @jimenezruizlab.bsky.social @meissnerlab.bsky.social: rupress.org/jcb/article/...
Vesicle adaptors in malaria parasites show conservation and flexibility of protein sorting machinery
Cubillán-Marín et al. find that the vesicle adaptors AP-1, AP-3, and AP-4 are all important for the survival of malaria blood-stage parasites and that thes
rupress.org
October 13, 2025 at 8:45 PM
See companion study from Grech et al. @jimenezruizlab.bsky.social @meissnerlab.bsky.social: rupress.org/jcb/article/...
Excited to share our new paper!
Tepsin and AP4 mediate transport from the trans-Golgi to the plant-like vacuole in Toxoplasma gondii.
A great collaboration between the Meissner, Jiménez-Ruiz, and Dacks labs 🙌
#Toxoplasma #Apicomplexa #Golgi #CellBiology #Parasites
Tepsin and AP4 mediate transport from the trans-Golgi to the plant-like vacuole in Toxoplasma gondii.
A great collaboration between the Meissner, Jiménez-Ruiz, and Dacks labs 🙌
#Toxoplasma #Apicomplexa #Golgi #CellBiology #Parasites
Tepsin and AP4 mediate transport from the trans-#Golgi to the plant-like vacuole in #toxoplasma, say Janessa Grech, Elena Jiménez-Ruiz @jimenezruizlab.bsky.social, Markus Meissner @meissnerlab.bsky.social & colleagues @lmumuenchen.bsky.social: rupress.org/jcb/article/...
#Microbiology #Cytoskeleton
#Microbiology #Cytoskeleton
October 20, 2025 at 1:36 PM
Excited to share our new paper!
Tepsin and AP4 mediate transport from the trans-Golgi to the plant-like vacuole in Toxoplasma gondii.
A great collaboration between the Meissner, Jiménez-Ruiz, and Dacks labs 🙌
#Toxoplasma #Apicomplexa #Golgi #CellBiology #Parasites
Tepsin and AP4 mediate transport from the trans-Golgi to the plant-like vacuole in Toxoplasma gondii.
A great collaboration between the Meissner, Jiménez-Ruiz, and Dacks labs 🙌
#Toxoplasma #Apicomplexa #Golgi #CellBiology #Parasites
Reposted by Jiménez-Ruiz Lab
See companion study from the Tobias Spielmann group: rupress.org/jcb/article/...
Vesicle adaptors in malaria parasites show conservation and flexibility of protein sorting machinery
Cubillán-Marín et al. find that the vesicle adaptors AP-1, AP-3, and AP-4 are all important for the survival of malaria blood-stage parasites and that thes
rupress.org
October 13, 2025 at 8:15 PM
See companion study from the Tobias Spielmann group: rupress.org/jcb/article/...
Reposted by Jiménez-Ruiz Lab
Grech, @jimenezruizlab.bsky.social @meissnerlab.bsky.social show that #Toxoplasma gondii tepsin interacts with the AP4 adaptor complex & #clathrin to mediate #actin- and #myosin F–dependent vesicle trafficking from the trans-#Golgi to the parasite’s #lysosome-like PLVAC rupress.org/jcb/article/...
October 13, 2025 at 8:15 PM
Grech, @jimenezruizlab.bsky.social @meissnerlab.bsky.social show that #Toxoplasma gondii tepsin interacts with the AP4 adaptor complex & #clathrin to mediate #actin- and #myosin F–dependent vesicle trafficking from the trans-#Golgi to the parasite’s #lysosome-like PLVAC rupress.org/jcb/article/...
Hi there! Our group at LMU Munich is hiring a postdoc to work on Toxoplasma and Plasmodium.
Start: from Oct 1, 2025 | Location: Munich, Germany
1-year contract with extension possible
Apply by Aug 31: bit.ly/LMUpostdoc
Contact: elena.jimenez@lmu.de
Start: from Oct 1, 2025 | Location: Munich, Germany
1-year contract with extension possible
Apply by Aug 31: bit.ly/LMUpostdoc
Contact: elena.jimenez@lmu.de
bit.ly
August 8, 2025 at 6:40 AM
Hi there! Our group at LMU Munich is hiring a postdoc to work on Toxoplasma and Plasmodium.
Start: from Oct 1, 2025 | Location: Munich, Germany
1-year contract with extension possible
Apply by Aug 31: bit.ly/LMUpostdoc
Contact: elena.jimenez@lmu.de
Start: from Oct 1, 2025 | Location: Munich, Germany
1-year contract with extension possible
Apply by Aug 31: bit.ly/LMUpostdoc
Contact: elena.jimenez@lmu.de
Exciting news from our department! Prof. Markus Meißner @meissnerlab.bsky.social and Prof. Gernot Längst teams made headlines with a breakthrough malaria drug, advancing the fight against this deadly disease. #Malaria #Research #WorldMalariaDay
#Malaria #Research #Innovation #WorldMalariaDay
#Malaria #Research #Innovation #WorldMalariaDay
Malaria-Wirkstoff aus Deutschland ein Durchbruch?
Deutsche Wissenschaftler haben einen vielversprechenden Wirkstoff gegen Malaria entwickelt. Doch die politischen Entwicklungen in den USA bedrohen ihre Arbeit. Von Frank Bäumer.
www.tagesschau.de
April 25, 2025 at 11:00 AM
Exciting news from our department! Prof. Markus Meißner @meissnerlab.bsky.social and Prof. Gernot Längst teams made headlines with a breakthrough malaria drug, advancing the fight against this deadly disease. #Malaria #Research #WorldMalariaDay
#Malaria #Research #Innovation #WorldMalariaDay
#Malaria #Research #Innovation #WorldMalariaDay
Nothing like some festive cheer to wrap up the year! 🎄✨ The lab had a fantastic time at the Christmas market in Munich—great company, cozy vibes, and lots of Glühwein!
Wishing everyone a joyful holiday season! 🎅❄️
Wishing everyone a joyful holiday season! 🎅❄️
December 17, 2024 at 4:42 PM
Nothing like some festive cheer to wrap up the year! 🎄✨ The lab had a fantastic time at the Christmas market in Munich—great company, cozy vibes, and lots of Glühwein!
Wishing everyone a joyful holiday season! 🎅❄️
Wishing everyone a joyful holiday season! 🎅❄️
Reposted by Jiménez-Ruiz Lab
Our new banners have arrived! 😍 Keep your eyes open for them so you don't miss any EXIT sessions at conferences!
#microbiology #parasitology #lifesciences #molecularbiology
#microbiology #parasitology #lifesciences #molecularbiology
December 11, 2024 at 12:31 PM
Our new banners have arrived! 😍 Keep your eyes open for them so you don't miss any EXIT sessions at conferences!
#microbiology #parasitology #lifesciences #molecularbiology
#microbiology #parasitology #lifesciences #molecularbiology
Reposted by Jiménez-Ruiz Lab
EastBio funded PhD opportunities in Edinburgh. Get in touch if you are interested in parasites and signalling.
9. How do ubiquitin writers control #malaria transmission?: tinyurl.com/5aus8tuw
So that's 9(!!) #Parasitology PhDs from the EastBio DTP at Edinburgh Uni! Get applying!
So that's 9(!!) #Parasitology PhDs from the EastBio DTP at Edinburgh Uni! Get applying!
EastBio: How do ubiquitin writers control malaria transmission? at University of Edinburgh on FindAPhD.com
PhD Project - EastBio: How do ubiquitin writers control malaria transmission? at University of Edinburgh, listed on FindAPhD.com
tinyurl.com
December 11, 2024 at 9:50 AM
EastBio funded PhD opportunities in Edinburgh. Get in touch if you are interested in parasites and signalling.
🌟 Welcome to the official account of the Jiménez Lab! 🌟 We are passionate about parasitology. Our primary focus is on understanding non-histone methylation in T.gondii.
Follow us for updates on our work, publications and more! 🚀
#Parasitology #ResearchLab #MolecularBiology #Methylation #Toxoplasma
Follow us for updates on our work, publications and more! 🚀
#Parasitology #ResearchLab #MolecularBiology #Methylation #Toxoplasma
November 17, 2024 at 8:19 AM
🌟 Welcome to the official account of the Jiménez Lab! 🌟 We are passionate about parasitology. Our primary focus is on understanding non-histone methylation in T.gondii.
Follow us for updates on our work, publications and more! 🚀
#Parasitology #ResearchLab #MolecularBiology #Methylation #Toxoplasma
Follow us for updates on our work, publications and more! 🚀
#Parasitology #ResearchLab #MolecularBiology #Methylation #Toxoplasma