Ivy L. Xiong
@ivyxiong.bsky.social
Oscillatory Dynamics in Mitochondria, Physiology and Cancer
https://lingyunxiong.github.io
https://lingyunxiong.github.io
Pinned
Ivy L. Xiong
@ivyxiong.bsky.social
· May 19
Very much appreciate the opportunity to present my research and connect with fellow rising stars last week @salkinstitute.bsky.social lingyunxiong.github.io/2025/05/01/S...
#DynamicsClub in November - SfN: 𝗝𝘂𝗻𝗵𝗲𝗻𝗴 𝗟𝗶 will share his work with Nir Grossman on bifurcation dynamics underlying falling asleep (PMID: 41152637) www.nature.com/articles/s41...
Nov 20 (Thursday) at 3pm PT / 6pm ET
Join us at UCLA or on Zoom: lingyunxiong.github.io/DynamicsClub/
Nov 20 (Thursday) at 3pm PT / 6pm ET
Join us at UCLA or on Zoom: lingyunxiong.github.io/DynamicsClub/
November 13, 2025 at 9:55 PM
#DynamicsClub in November - SfN: 𝗝𝘂𝗻𝗵𝗲𝗻𝗴 𝗟𝗶 will share his work with Nir Grossman on bifurcation dynamics underlying falling asleep (PMID: 41152637) www.nature.com/articles/s41...
Nov 20 (Thursday) at 3pm PT / 6pm ET
Join us at UCLA or on Zoom: lingyunxiong.github.io/DynamicsClub/
Nov 20 (Thursday) at 3pm PT / 6pm ET
Join us at UCLA or on Zoom: lingyunxiong.github.io/DynamicsClub/
Elegant!
Flashback #FluorescenceFriday to some of the first light-sheet imaging we were doing. Video shows the collecting duct system of the developing kidney labeled with a pan-cytokeratin antibody. Courtesy of former talented technician Deanna Hardesty.
November 7, 2025 at 5:58 PM
Elegant!
#DynamicsClub in November: 𝗠𝗶𝗰𝗵𝗮𝗲𝗹 𝗦𝗮𝗻𝗱𝗹𝗲𝗿 will share his work with Suckjoon Jun on dynamic pattern formation of Min protein in E. coli (PMID: 40678616) www.nature.com/articles/s41...
Nov 4 (Tuesday) at 11am PT / 2pm ET
Join us at UCLA or on Zoom: lingyunxiong.github.io/DynamicsClub/
Nov 4 (Tuesday) at 11am PT / 2pm ET
Join us at UCLA or on Zoom: lingyunxiong.github.io/DynamicsClub/
November 2, 2025 at 5:27 PM
#DynamicsClub in November: 𝗠𝗶𝗰𝗵𝗮𝗲𝗹 𝗦𝗮𝗻𝗱𝗹𝗲𝗿 will share his work with Suckjoon Jun on dynamic pattern formation of Min protein in E. coli (PMID: 40678616) www.nature.com/articles/s41...
Nov 4 (Tuesday) at 11am PT / 2pm ET
Join us at UCLA or on Zoom: lingyunxiong.github.io/DynamicsClub/
Nov 4 (Tuesday) at 11am PT / 2pm ET
Join us at UCLA or on Zoom: lingyunxiong.github.io/DynamicsClub/
Application for the 3rd Annual Rising Stars Symposium @salkinstitute.bsky.social is now open! I'm happy to share that I had a wonderful time learning from peers and Salk faculties back in May.
October 28, 2025 at 4:02 PM
Application for the 3rd Annual Rising Stars Symposium @salkinstitute.bsky.social is now open! I'm happy to share that I had a wonderful time learning from peers and Salk faculties back in May.
#DynamicsClub in October: 𝗣𝗮𝗼𝗹𝗼 𝗖𝗮𝗹𝗱𝗮𝗿𝗲𝗹𝗹𝗶 will share his work on mechanical control of gastrulation dynamics (PMID: 39261736) www.nature.com/articles/s41...
Oct 27 (Monday) at 9am PT / 12noon ET / 5pm CET
Join us on Zoom: lingyunxiong.github.io/DynamicsClub/
Oct 27 (Monday) at 9am PT / 12noon ET / 5pm CET
Join us on Zoom: lingyunxiong.github.io/DynamicsClub/
October 16, 2025 at 7:23 PM
#DynamicsClub in October: 𝗣𝗮𝗼𝗹𝗼 𝗖𝗮𝗹𝗱𝗮𝗿𝗲𝗹𝗹𝗶 will share his work on mechanical control of gastrulation dynamics (PMID: 39261736) www.nature.com/articles/s41...
Oct 27 (Monday) at 9am PT / 12noon ET / 5pm CET
Join us on Zoom: lingyunxiong.github.io/DynamicsClub/
Oct 27 (Monday) at 9am PT / 12noon ET / 5pm CET
Join us on Zoom: lingyunxiong.github.io/DynamicsClub/
#DynamicsClub in September: 𝗡𝗶𝗰𝗼𝗹𝗲 𝗕𝗿𝘂𝗰𝗲 will share her work with Richard Bertram on coordinated oscillations in pancreatic islets. PMID: 36223522, 39066476
Sep 16 (Tue) at 11am PT / 2pm ET
Join us on Zoom: lingyunxiong.github.io/DynamicsClub/
Sep 16 (Tue) at 11am PT / 2pm ET
Join us on Zoom: lingyunxiong.github.io/DynamicsClub/
September 16, 2025 at 4:48 PM
#DynamicsClub in September: 𝗡𝗶𝗰𝗼𝗹𝗲 𝗕𝗿𝘂𝗰𝗲 will share her work with Richard Bertram on coordinated oscillations in pancreatic islets. PMID: 36223522, 39066476
Sep 16 (Tue) at 11am PT / 2pm ET
Join us on Zoom: lingyunxiong.github.io/DynamicsClub/
Sep 16 (Tue) at 11am PT / 2pm ET
Join us on Zoom: lingyunxiong.github.io/DynamicsClub/
Reposted by Ivy L. Xiong
Priyom's preprint is out on biorxiv. See below for a detailed thread. In a nutshell, she has discovered and characterized the oscillator that times notochord and spine segmentation in zebrafish. Turns out that there are uniform Erk oscillations across the entire tissue that act as timekeepers!
Building a spine is no joke, but thankfully zebrafish have their own clocks to keep the pace. Excited to share our preprint on the role of biological oscillators in coordinating notochord development! (www.biorxiv.org/content/10.1...)
Additional thread below
Additional thread below
September 2, 2025 at 5:34 PM
Priyom's preprint is out on biorxiv. See below for a detailed thread. In a nutshell, she has discovered and characterized the oscillator that times notochord and spine segmentation in zebrafish. Turns out that there are uniform Erk oscillations across the entire tissue that act as timekeepers!
#DynamicsClub in August: 𝗪𝗲𝗻𝗯𝗼 𝗧𝗮𝗻𝗴 at Cornell University will share her work on pupil dynamics in sleep and memory replay. pubmed.ncbi.nlm.nih.gov/39743590/
Aug 12 (Tue) at 11am PT / 2pm ET
Join us on Zoom: lingyunxiong.github.io/DynamicsClub/
Aug 12 (Tue) at 11am PT / 2pm ET
Join us on Zoom: lingyunxiong.github.io/DynamicsClub/
August 6, 2025 at 8:59 PM
#DynamicsClub in August: 𝗪𝗲𝗻𝗯𝗼 𝗧𝗮𝗻𝗴 at Cornell University will share her work on pupil dynamics in sleep and memory replay. pubmed.ncbi.nlm.nih.gov/39743590/
Aug 12 (Tue) at 11am PT / 2pm ET
Join us on Zoom: lingyunxiong.github.io/DynamicsClub/
Aug 12 (Tue) at 11am PT / 2pm ET
Join us on Zoom: lingyunxiong.github.io/DynamicsClub/
Reposted by Ivy L. Xiong
1/27 We have a new paper out! Turns out that snowflake yeast have been hiding a secret from us - they've evolved a (very!) crude circulatory system. Not with blood vessels or a heart, but through spontaneous fluid flows powered by their metabolism. 🧪🔬
www.science.org/doi/full/10....
www.science.org/doi/full/10....
June 24, 2025 at 4:52 PM
1/27 We have a new paper out! Turns out that snowflake yeast have been hiding a secret from us - they've evolved a (very!) crude circulatory system. Not with blood vessels or a heart, but through spontaneous fluid flows powered by their metabolism. 🧪🔬
www.science.org/doi/full/10....
www.science.org/doi/full/10....
Another excellent opportunity to share some new ideas and thoughts about my ongoing research on renal physiology!
It’s high time to tinker about electrophysiology, cardiology as well as neurobiology! 🤓
It’s high time to tinker about electrophysiology, cardiology as well as neurobiology! 🤓
June 9, 2025 at 7:23 PM
Another excellent opportunity to share some new ideas and thoughts about my ongoing research on renal physiology!
It’s high time to tinker about electrophysiology, cardiology as well as neurobiology! 🤓
It’s high time to tinker about electrophysiology, cardiology as well as neurobiology! 🤓
It was tremendous fun to give a department seminar like this one! 🥳
June 7, 2025 at 3:09 AM
It was tremendous fun to give a department seminar like this one! 🥳
Super excited to wrap up the spring quarter as the last seminar speaker at UCSD Bioengineering!
I’m thrilled to meet Shu Chien this morning, and looking forward to more discussions this afternoon.
I’m thrilled to meet Shu Chien this morning, and looking forward to more discussions this afternoon.
June 6, 2025 at 8:38 PM
Super excited to wrap up the spring quarter as the last seminar speaker at UCSD Bioengineering!
I’m thrilled to meet Shu Chien this morning, and looking forward to more discussions this afternoon.
I’m thrilled to meet Shu Chien this morning, and looking forward to more discussions this afternoon.
Delighted to share that I will give a department seminar at UCSD 𝑺𝒉𝒖 𝑪𝒉𝒊𝒆𝒏 - 𝑮𝒆𝒏𝒆 𝑳𝒂𝒚 𝑫𝒆𝒑𝒂𝒓𝒕𝒎𝒆𝒏𝒕 𝒐𝒇 𝑩𝒊𝒐𝒆𝒏𝒈𝒊𝒏𝒆𝒆𝒓𝒊𝒏𝒈 on Friday, June 6th. be.ucsd.edu/seminar/2025...
Join us in La Jolla at 2pm in The FUNG Auditorium.
Join us in La Jolla at 2pm in The FUNG Auditorium.
Bifurcation theory in physiology | Shu Chien - Gene Lay Department of Bioengineering
be.ucsd.edu
June 2, 2025 at 10:48 PM
Delighted to share that I will give a department seminar at UCSD 𝑺𝒉𝒖 𝑪𝒉𝒊𝒆𝒏 - 𝑮𝒆𝒏𝒆 𝑳𝒂𝒚 𝑫𝒆𝒑𝒂𝒓𝒕𝒎𝒆𝒏𝒕 𝒐𝒇 𝑩𝒊𝒐𝒆𝒏𝒈𝒊𝒏𝒆𝒆𝒓𝒊𝒏𝒈 on Friday, June 6th. be.ucsd.edu/seminar/2025...
Join us in La Jolla at 2pm in The FUNG Auditorium.
Join us in La Jolla at 2pm in The FUNG Auditorium.
#DynamicsClub in June: 𝗖𝗮𝘀𝗲𝘆 𝗔𝗱𝗮𝗺 from Purdue University will share her work on dynamic neuromodulation. www.nature.com/articles/s42...
June 12 (Thur) at 11am PT / 2pm ET
Join in person at UCLA or on Zoom: lingyunxiong.github.io/DynamicsClub/
June 12 (Thur) at 11am PT / 2pm ET
Join in person at UCLA or on Zoom: lingyunxiong.github.io/DynamicsClub/
June 2, 2025 at 10:13 PM
#DynamicsClub in June: 𝗖𝗮𝘀𝗲𝘆 𝗔𝗱𝗮𝗺 from Purdue University will share her work on dynamic neuromodulation. www.nature.com/articles/s42...
June 12 (Thur) at 11am PT / 2pm ET
Join in person at UCLA or on Zoom: lingyunxiong.github.io/DynamicsClub/
June 12 (Thur) at 11am PT / 2pm ET
Join in person at UCLA or on Zoom: lingyunxiong.github.io/DynamicsClub/
I have been selected by the UCLA Molecular Biology Institute for the 2025 Boyer/Parvin Posteoctoral Award. 🥳🥳🥳
Initiated by Paul Boyer since his Nobel Prize in 1997, this honor is now supported by the Parvin foundation to celebrate the legacy of Dr. Boyer, beyond ATP synthase and the sodium pump.
Initiated by Paul Boyer since his Nobel Prize in 1997, this honor is now supported by the Parvin foundation to celebrate the legacy of Dr. Boyer, beyond ATP synthase and the sodium pump.
June 1, 2025 at 3:01 PM
I have been selected by the UCLA Molecular Biology Institute for the 2025 Boyer/Parvin Posteoctoral Award. 🥳🥳🥳
Initiated by Paul Boyer since his Nobel Prize in 1997, this honor is now supported by the Parvin foundation to celebrate the legacy of Dr. Boyer, beyond ATP synthase and the sodium pump.
Initiated by Paul Boyer since his Nobel Prize in 1997, this honor is now supported by the Parvin foundation to celebrate the legacy of Dr. Boyer, beyond ATP synthase and the sodium pump.
Constantly mind-blowing to learn how mitochondria adapt bioenergetically during “intensive exercise”, especially in the case of long-distance avian migration!
The yellow-rumped warbler, also known as the butterbutt, is a versatile forager, catching bugs in spring and eating berries in fall. A recent study of the bird has shown how mitochondria transform when birds migrate. www.quantamagazine.org/turbocharged...
May 20, 2025 at 7:41 PM
Constantly mind-blowing to learn how mitochondria adapt bioenergetically during “intensive exercise”, especially in the case of long-distance avian migration!
Such an introspective conversation about the cognitive process of scientific inquiries! From a scientist who never fails to inspire.
podcasts.apple.com/us/podcast/n...
podcasts.apple.com/us/podcast/n...
74 | Martin Schwartz and the importance of stupidity in science
Podcast Episode · Night Science · 04/21/2025 · 29m
podcasts.apple.com
May 20, 2025 at 5:08 PM
Such an introspective conversation about the cognitive process of scientific inquiries! From a scientist who never fails to inspire.
podcasts.apple.com/us/podcast/n...
podcasts.apple.com/us/podcast/n...
Very much appreciate the opportunity to present my research and connect with fellow rising stars last week @salkinstitute.bsky.social lingyunxiong.github.io/2025/05/01/S...
May 19, 2025 at 7:52 PM
Very much appreciate the opportunity to present my research and connect with fellow rising stars last week @salkinstitute.bsky.social lingyunxiong.github.io/2025/05/01/S...
It's fun to read about the scientific journey of Dr. Correa and her work. Truly delighted to have such role models in the department at UCLA.
Our latest profile is here! Dr. Stephanie Correa studies how reproductive hormones regulate development and neural circuits for temperature and energy balance. Click the link below to listen and learn more!
www.storiesofwin.org/profiles/202...
#StoriesOfWiN #WomenInNeuroscience
www.storiesofwin.org/profiles/202...
#StoriesOfWiN #WomenInNeuroscience
May 19, 2025 at 4:36 AM
It's fun to read about the scientific journey of Dr. Correa and her work. Truly delighted to have such role models in the department at UCLA.
"No longer viewed as a metabolic waste product and cause of muscle fatigue... " 𝙇𝙖𝙘𝙩𝙖𝙩𝙚 𝙖𝙨 𝙖 𝙢𝙮𝙤𝙠𝙞𝙣𝙚 𝙖𝙣𝙙 𝙚𝙭𝙚𝙧𝙠𝙞𝙣𝙚: 𝙙𝙧𝙞𝙫𝙚𝙧𝙨 𝙖𝙣𝙙 𝙨𝙞𝙜𝙣𝙖𝙡𝙨 𝙤𝙛 𝙥𝙝𝙮𝙨𝙞𝙤𝙡𝙤𝙜𝙮 𝙖𝙣𝙙 𝙢𝙚𝙩𝙖𝙗𝙤𝙡𝙞𝙨𝙢 journals.physiology.org/doi/full/10....
May 9, 2025 at 11:31 PM
"No longer viewed as a metabolic waste product and cause of muscle fatigue... " 𝙇𝙖𝙘𝙩𝙖𝙩𝙚 𝙖𝙨 𝙖 𝙢𝙮𝙤𝙠𝙞𝙣𝙚 𝙖𝙣𝙙 𝙚𝙭𝙚𝙧𝙠𝙞𝙣𝙚: 𝙙𝙧𝙞𝙫𝙚𝙧𝙨 𝙖𝙣𝙙 𝙨𝙞𝙜𝙣𝙖𝙡𝙨 𝙤𝙛 𝙥𝙝𝙮𝙨𝙞𝙤𝙡𝙤𝙜𝙮 𝙖𝙣𝙙 𝙢𝙚𝙩𝙖𝙗𝙤𝙡𝙞𝙨𝙢 journals.physiology.org/doi/full/10....
Reposted by Ivy L. Xiong
Milestones is an annual publication covering the exciting research performed at the National Cancer Institute, NIH. This year, my group is honored to be included!
It's truly a privilege to work with @poratshliomlab.bsky.social at NIH/NCI on understanding metabolic multi-tasking at the tissue level, in the liver and in the kidney.
Congrats to the entire lab for the highlight (on p.20) as well as the stunning cover image! 🎉
ccr.cancer.gov/news/milesto...
Congrats to the entire lab for the highlight (on p.20) as well as the stunning cover image! 🎉
ccr.cancer.gov/news/milesto...
CCR Milestones - 2025 | Center for Cancer Research
Every year, CCR makes remarkable contributions to the understanding, detection, treatment and prevention of cancer. This digital-only issue of our annual publication, Milestones, features 13 of our to...
ccr.cancer.gov
May 9, 2025 at 5:25 PM
Milestones is an annual publication covering the exciting research performed at the National Cancer Institute, NIH. This year, my group is honored to be included!
It's truly a privilege to work with @poratshliomlab.bsky.social at NIH/NCI on understanding metabolic multi-tasking at the tissue level, in the liver and in the kidney.
Congrats to the entire lab for the highlight (on p.20) as well as the stunning cover image! 🎉
ccr.cancer.gov/news/milesto...
Congrats to the entire lab for the highlight (on p.20) as well as the stunning cover image! 🎉
ccr.cancer.gov/news/milesto...
CCR Milestones - 2025 | Center for Cancer Research
Every year, CCR makes remarkable contributions to the understanding, detection, treatment and prevention of cancer. This digital-only issue of our annual publication, Milestones, features 13 of our to...
ccr.cancer.gov
May 9, 2025 at 1:54 AM
It's truly a privilege to work with @poratshliomlab.bsky.social at NIH/NCI on understanding metabolic multi-tasking at the tissue level, in the liver and in the kidney.
Congrats to the entire lab for the highlight (on p.20) as well as the stunning cover image! 🎉
ccr.cancer.gov/news/milesto...
Congrats to the entire lab for the highlight (on p.20) as well as the stunning cover image! 🎉
ccr.cancer.gov/news/milesto...
#DynamicsClub in May: 𝗡𝗮𝘁𝗮𝗹𝗶𝗲 𝗛𝗮𝘂𝗴𝗹𝘂𝗻𝗱 @ox.ac.uk will share her recent work on the glymphatic system during sleep. pubmed.ncbi.nlm.nih.gov/39788123/
May 7 (Wed) at 9am PT / 5pm BST
Join us on Zoom: lingyunxiong.github.io/DynamicsClub/
May 7 (Wed) at 9am PT / 5pm BST
Join us on Zoom: lingyunxiong.github.io/DynamicsClub/
May 1, 2025 at 3:43 PM
#DynamicsClub in May: 𝗡𝗮𝘁𝗮𝗹𝗶𝗲 𝗛𝗮𝘂𝗴𝗹𝘂𝗻𝗱 @ox.ac.uk will share her recent work on the glymphatic system during sleep. pubmed.ncbi.nlm.nih.gov/39788123/
May 7 (Wed) at 9am PT / 5pm BST
Join us on Zoom: lingyunxiong.github.io/DynamicsClub/
May 7 (Wed) at 9am PT / 5pm BST
Join us on Zoom: lingyunxiong.github.io/DynamicsClub/
Reposted by Ivy L. Xiong
Is liver zonation conserved from mice to humans? And how does fibrosis affect zonation in patients? Now, these questions are answered using scDVP. Some collaborations are meant to be! @carolineweiss.bsky.social@frosenberger.bsky.social @mannlab.bsky.social@mlsb-borgwardt.bsky.social
Introducing our single-cell DVP framework combining strategic cell selection with protein gradient mapping algorithms. Analyzing hepatocyte proteomes across 18 human livers, revealing cross-species differences, and mapping disruptions in liver fibrosis.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
April 14, 2025 at 2:35 PM
Is liver zonation conserved from mice to humans? And how does fibrosis affect zonation in patients? Now, these questions are answered using scDVP. Some collaborations are meant to be! @carolineweiss.bsky.social@frosenberger.bsky.social @mannlab.bsky.social@mlsb-borgwardt.bsky.social
My article with @agarfinkel.bsky.social titled "𝗔𝗿𝗲 𝗽𝗵𝘆𝘀𝗶𝗼𝗹𝗼𝗴𝗶𝗰𝗮𝗹 𝗼𝘀𝗰𝗶𝗹𝗹𝗮𝘁𝗶𝗼𝗻𝘀 𝙥𝙝𝙮𝙨𝙞𝙤𝙡𝙤𝙜𝙞𝙘𝙖𝙡?" has ranked as a Top Viewed Article by Wiley. Check it out if you haven't done so: onlinelibrary.wiley.com/doi/full/10.... #TopViewedArticle
Are physiological oscillations physiological?
Abstract figure legend Mechanisms and functions of physiological oscillations.
onlinelibrary.wiley.com
April 16, 2025 at 1:46 PM
My article with @agarfinkel.bsky.social titled "𝗔𝗿𝗲 𝗽𝗵𝘆𝘀𝗶𝗼𝗹𝗼𝗴𝗶𝗰𝗮𝗹 𝗼𝘀𝗰𝗶𝗹𝗹𝗮𝘁𝗶𝗼𝗻𝘀 𝙥𝙝𝙮𝙨𝙞𝙤𝙡𝙤𝙜𝙞𝙘𝙖𝙡?" has ranked as a Top Viewed Article by Wiley. Check it out if you haven't done so: onlinelibrary.wiley.com/doi/full/10.... #TopViewedArticle