Ishrat Husain
@ishrathusain.bsky.social
Department Head, Program Medical Director, Psychiatrist, Senior Scientist - UHN-CAMH
Associate Professor of Psychiatry, Cameron Wilson Chair in Depression Studies - University of Toronto
Associate Professor of Psychiatry, Cameron Wilson Chair in Depression Studies - University of Toronto
Measurement-based care (MBC) is a scalable approach to improving outcomes for people with depression. We implemented MBC across sites in Pakistan & showed that MBC reduced time to antidepressant response & remission by HALF compared with standard care.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Measurement-Based Care to Enhance Outcomes in Major Depressive Disorder
This randomized clinical trial evaluates whether adults receiving measurement-based care vs standard care for major depressive disorder have faster response and remission times.
jamanetwork.com
September 5, 2025 at 12:45 AM
Measurement-based care (MBC) is a scalable approach to improving outcomes for people with depression. We implemented MBC across sites in Pakistan & showed that MBC reduced time to antidepressant response & remission by HALF compared with standard care.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Great to be in Crete for @assc28.bsky.social presenting designs of our innovative clinical trials of psilocybin therapy @camhnews.bsky.social and @uhnresearch.ca. My first time presenting outdoors in the sun!
July 8, 2025 at 10:08 AM
Great to be in Crete for @assc28.bsky.social presenting designs of our innovative clinical trials of psilocybin therapy @camhnews.bsky.social and @uhnresearch.ca. My first time presenting outdoors in the sun!
Reposted by Ishrat Husain
New in @naturemedicine.bsky.social
"An international Delphi consensus for reporting of setting in psychedelic clinical trials" by Chloé Pronovost-Morgan, Kyle Greenway, myself, and many ReSPCT Experts." nature.com/articles/s41...
"An international Delphi consensus for reporting of setting in psychedelic clinical trials" by Chloé Pronovost-Morgan, Kyle Greenway, myself, and many ReSPCT Experts." nature.com/articles/s41...
An international Delphi consensus for reporting of setting in psychedelic clinical trials - Nature Medicine
A large international panel of experts reach consensus on a new standard for reporting settings in psychedelic trials, identifying 30 key non-pharmacological factors to strengthen the rigor of psyched...
nature.com
June 3, 2025 at 9:30 AM
New in @naturemedicine.bsky.social
"An international Delphi consensus for reporting of setting in psychedelic clinical trials" by Chloé Pronovost-Morgan, Kyle Greenway, myself, and many ReSPCT Experts." nature.com/articles/s41...
"An international Delphi consensus for reporting of setting in psychedelic clinical trials" by Chloé Pronovost-Morgan, Kyle Greenway, myself, and many ReSPCT Experts." nature.com/articles/s41...
Elegant study linking early life maternal warmth to feelings of social safety (belonging) in adolescence, which then influences physical & mental health outcomes in late teens.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Childhood Maternal Warmth and Adolescent Health
This cohort study examines how maternal warmth at 3 years of age shapes adolescent social safety schemas at 14 years of age and physical and mental health at 17 years of age.
jamanetwork.com
May 28, 2025 at 7:20 PM
Elegant study linking early life maternal warmth to feelings of social safety (belonging) in adolescence, which then influences physical & mental health outcomes in late teens.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Reposted by Ishrat Husain
“At UHN, we don’t see mental and physical health as separate. We’re disrupting that false divide with holistic, integrated care.” – Dr. Ishrat Husain, Department Head of UHN Centre for Mental Health & Program Medical Director of the UHN-CAMH Partnership.
#MentalHealthWeek
#MentalHealthWeek
May 7, 2025 at 5:02 PM
“At UHN, we don’t see mental and physical health as separate. We’re disrupting that false divide with holistic, integrated care.” – Dr. Ishrat Husain, Department Head of UHN Centre for Mental Health & Program Medical Director of the UHN-CAMH Partnership.
#MentalHealthWeek
#MentalHealthWeek
Reposted by Ishrat Husain
#ThisWeekInNPP
This systematic review & meta-analysis from @ishrathusain.bsky.social & team found that structural changes in grey & white matter are moderately associated w/ cognitive deficits in bipolar disorder, w/⬆️ associations in bipolar I & euthymic individuals
www.nature.com/articles/s41...
This systematic review & meta-analysis from @ishrathusain.bsky.social & team found that structural changes in grey & white matter are moderately associated w/ cognitive deficits in bipolar disorder, w/⬆️ associations in bipolar I & euthymic individuals
www.nature.com/articles/s41...
Associations between structural brain measures and cognitive function in bipolar disorder: a systematic review and meta-analysis - Neuropsychopharmacology
Neuropsychopharmacology - Associations between structural brain measures and cognitive function in bipolar disorder: a systematic review and meta-analysis
www.nature.com
May 6, 2025 at 10:17 PM
#ThisWeekInNPP
This systematic review & meta-analysis from @ishrathusain.bsky.social & team found that structural changes in grey & white matter are moderately associated w/ cognitive deficits in bipolar disorder, w/⬆️ associations in bipolar I & euthymic individuals
www.nature.com/articles/s41...
This systematic review & meta-analysis from @ishrathusain.bsky.social & team found that structural changes in grey & white matter are moderately associated w/ cognitive deficits in bipolar disorder, w/⬆️ associations in bipolar I & euthymic individuals
www.nature.com/articles/s41...
Reposted by Ishrat Husain
Learn from the world-leading hub for brain-related research and care during #BrainAwarenessWeek! 🧠
Follow along with @kbi-uhn.bsky.social and check out the Your Complex Brain podcast for more!
Follow along with @kbi-uhn.bsky.social and check out the Your Complex Brain podcast for more!
This week is #BrainAwarenessWeek 🧠
Watch the video below to learn more⬇️ 🫂
🔗: linktr.ee/krembil
@uhnresearch.bsky.social
@dkjei-uhn.bsky.social
@uhntoronto.bsky.social
@schroeder-uhn.bsky.social
@kiteuhn.bsky.social
@krembilfoundation.bsky.social
@uhnfoundation.bsky.social
Watch the video below to learn more⬇️ 🫂
🔗: linktr.ee/krembil
@uhnresearch.bsky.social
@dkjei-uhn.bsky.social
@uhntoronto.bsky.social
@schroeder-uhn.bsky.social
@kiteuhn.bsky.social
@krembilfoundation.bsky.social
@uhnfoundation.bsky.social
March 12, 2025 at 6:00 PM
Learn from the world-leading hub for brain-related research and care during #BrainAwarenessWeek! 🧠
Follow along with @kbi-uhn.bsky.social and check out the Your Complex Brain podcast for more!
Follow along with @kbi-uhn.bsky.social and check out the Your Complex Brain podcast for more!
Reposted by Ishrat Husain
University Health Network is proud to be named by Brand Finance as the leading Canadian academic health sciences centre in their Global Top 250 Hospitals 2025 report.
Access the full 2025 report here:
brandirectory.com/reports/hosp...
Access the full 2025 report here:
brandirectory.com/reports/hosp...
February 6, 2025 at 4:45 PM
University Health Network is proud to be named by Brand Finance as the leading Canadian academic health sciences centre in their Global Top 250 Hospitals 2025 report.
Access the full 2025 report here:
brandirectory.com/reports/hosp...
Access the full 2025 report here:
brandirectory.com/reports/hosp...
Reposted by Ishrat Husain
CAMH is now on Bluesky!
We’re excited to continue engaging with our community and sharing the work we’re doing, alongside our partners, shaping a future where #MentalHealthisHealth.
We’re excited to continue engaging with our community and sharing the work we’re doing, alongside our partners, shaping a future where #MentalHealthisHealth.
January 21, 2025 at 2:43 PM
CAMH is now on Bluesky!
We’re excited to continue engaging with our community and sharing the work we’re doing, alongside our partners, shaping a future where #MentalHealthisHealth.
We’re excited to continue engaging with our community and sharing the work we’re doing, alongside our partners, shaping a future where #MentalHealthisHealth.
Reposted by Ishrat Husain
Big co-1st/corresponding author paper just published in
@JAMAPsychiatry!
I just can't thank our team enough for their unwavering support on this project.
Modifying Informed Consent to Help Address Functional Unmasking in Psychedelic Clinical Trials
jamanetwork.com/journals/jam...
@JAMAPsychiatry!
I just can't thank our team enough for their unwavering support on this project.
Modifying Informed Consent to Help Address Functional Unmasking in Psychedelic Clinical Trials
jamanetwork.com/journals/jam...
Modifying Informed Consent to Help Address Functional Unmasking in Psychedelic Clinical Trials
This narrative review describes clinical trials of psychedelic or MDMA therapy and reports from the investigators on the use of modifications to informed consent in these studies.
jamanetwork.com
January 8, 2025 at 6:30 PM
Big co-1st/corresponding author paper just published in
@JAMAPsychiatry!
I just can't thank our team enough for their unwavering support on this project.
Modifying Informed Consent to Help Address Functional Unmasking in Psychedelic Clinical Trials
jamanetwork.com/journals/jam...
@JAMAPsychiatry!
I just can't thank our team enough for their unwavering support on this project.
Modifying Informed Consent to Help Address Functional Unmasking in Psychedelic Clinical Trials
jamanetwork.com/journals/jam...
Reposted by Ishrat Husain
"A study of federally funded research projects in the United States estimated that principal investigators spend on average about 45% of their time on administrative activities related to applying for and managing projects rather than conducting active research"
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
January 4, 2025 at 1:26 PM
"A study of federally funded research projects in the United States estimated that principal investigators spend on average about 45% of their time on administrative activities related to applying for and managing projects rather than conducting active research"
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Until researchers improve reporting of the psychological support components in psychedelic therapies, regulators will comtinue to withhold approval for clinical use. www.thelancet.com/journals/lan...
Quality of reporting on psychological interventions in psychedelic treatments: a systematic review
Although studies of psychedelic-assisted psychotherapy are accumulating, there is no consensus regarding best practice of the psychotherapeutic component. In this systematic review, we summarised the quality of reporting on psychological interventions in research about psychedelic treatments. The design followed PRISMA guidelines and was preregistered in PROSPERO (CRD42022319221). We searched MEDLINE, PsycINFO, and Embase for original studies on psychedelic-assisted psychotherapy and included 45 studies assessing psilocybin, 3,4-methylenedioxymethamphetamine (MDMA), lysergic acid diethylamide (known as LSD), or ayahuasca, for the treatment of mental disorders.
www.thelancet.com
December 18, 2024 at 3:29 PM
Until researchers improve reporting of the psychological support components in psychedelic therapies, regulators will comtinue to withhold approval for clinical use. www.thelancet.com/journals/lan...
Reposted by Ishrat Husain
Reposted by Ishrat Husain
It’s high time the field of psychedelic research move beyond the mystical experience construct (MEQ). While many critiques of the measure rest on misconceptions, persistent misunderstandings & psychometric limitations lead us to recommend transcending it.
- Nature R Psy: nature.com/articles/s44...
- Nature R Psy: nature.com/articles/s44...
Clinically relevant acute subjective effects of psychedelics beyond mystical experience - Nature Reviews Psychology
The therapeutic benefits of psychedelics might be ascribed to their subjective effects, but methodological barriers limit interpretation of this association. In this Review, Yaden et al. balance the l...
nature.com
November 27, 2024 at 4:49 PM
It’s high time the field of psychedelic research move beyond the mystical experience construct (MEQ). While many critiques of the measure rest on misconceptions, persistent misunderstandings & psychometric limitations lead us to recommend transcending it.
- Nature R Psy: nature.com/articles/s44...
- Nature R Psy: nature.com/articles/s44...
Reposted by Ishrat Husain
Is there a formula for competitive grant applications?
Araj et al. break down the core elements of successful proposals in their latest perspective article!
www.pnas.org/doi/10.1073/...
Araj et al. break down the core elements of successful proposals in their latest perspective article!
www.pnas.org/doi/10.1073/...
Elements of successful NIH grant applications | PNAS
Is there a formula for a competitive NIH grant application? The Serenity Prayer may
provide one: "Grant me the serenity to accept the things I cann...
www.pnas.org
November 26, 2024 at 9:35 PM
Is there a formula for competitive grant applications?
Araj et al. break down the core elements of successful proposals in their latest perspective article!
www.pnas.org/doi/10.1073/...
Araj et al. break down the core elements of successful proposals in their latest perspective article!
www.pnas.org/doi/10.1073/...
Reposted by Ishrat Husain
‘Resilience interventions do work’ – why coping strategies should be a staple of education
‘Resilience interventions do work’ – why coping strategies should be a staple of education
Early instruction that teaches young people how to recognise negative thought patterns and manage their mental health may help to avoid problems in later life
I was about 16 when I had my first bout of depression, but 29 when I sought help and received a…
www.theguardian.com
November 24, 2024 at 2:18 PM
‘Resilience interventions do work’ – why coping strategies should be a staple of education
Hello BlueSky, I've made the jump over and already feel emotionally and psychologically lighter! Looking forward to connecting you all on this less divisive platform.
November 23, 2024 at 12:46 AM
Hello BlueSky, I've made the jump over and already feel emotionally and psychologically lighter! Looking forward to connecting you all on this less divisive platform.