Iseult
@iseultjackson.bsky.social
Postdoc researching ancient pathogen genomics 🦠⏳💀| Interested in ancient genomes and disease genetics | she/her 🏳️🌈
Reposted by Iseult
🖋️ really happy to be a part of @the4facedliar.bsky.social's upcoming issue - can't believe I was highly commended! I'm looking forward to reading the rest 📖
Congratulations to the winning & Highly Commended authors of or Creative Non-Fiction competition chosen by judge Tim MacGabhann! Their work will be published in Issue 4. Thanks to all who entered @writing.ie @irishpen.bsky.social @irishwriterscentre.bsky.social
October 1, 2025 at 7:58 PM
🖋️ really happy to be a part of @the4facedliar.bsky.social's upcoming issue - can't believe I was highly commended! I'm looking forward to reading the rest 📖
Reposted by Iseult
Interested in goats 🐐? Read our pre-print on ancient Irish goats and their connection to the Old Irish goat breed
Just look at this dashing individual, courtesy of the Old Irish Goat society
Just look at this dashing individual, courtesy of the Old Irish Goat society
September 29, 2025 at 8:47 AM
Interested in goats 🐐? Read our pre-print on ancient Irish goats and their connection to the Old Irish goat breed
Just look at this dashing individual, courtesy of the Old Irish Goat society
Just look at this dashing individual, courtesy of the Old Irish Goat society
🦠💀🦠 Happy to share our (with @gunnar-u-neumann.bsky.social) new preprint on ancient Salmonella enterica genomes! We analysed 53 new genomes along with published ancient and modern datasets to learn about lineage replacements and host adaptation in prehistory: www.biorxiv.org/content/10.1...
Evolutionary history and recurrent host adaptation in ancient Salmonella enterica
Salmonella enterica subsp. enterica is an extremely diverse bacterial pathogen causing frequent infections and foodborne disease among human populations. More than 1500 different bacterial strains (se...
www.biorxiv.org
September 22, 2025 at 6:19 PM
🦠💀🦠 Happy to share our (with @gunnar-u-neumann.bsky.social) new preprint on ancient Salmonella enterica genomes! We analysed 53 new genomes along with published ancient and modern datasets to learn about lineage replacements and host adaptation in prehistory: www.biorxiv.org/content/10.1...
🌊🏠🌅
So my first ever article from my PhD, 'Returning to Home Water(s) in Nostalgie de la rizière by Anna Moï' 🌊🏠, has recently been published in a special issue! It explores Vietnamese diasporic writing, conceptions of home, and is available - open access - here:
Returning to Home Water(s) in Nostalgie de la rizière by Anna Moï: Ingenta Connect
www.ingentaconnect.com
September 14, 2025 at 7:25 AM
🌊🏠🌅
Reposted by Iseult
Second craziest thing you'll read today: from 2026 I will be leading an @erc.europa.eu Starter Grant project. HERDPATH will explore how livestock and their pathogens co-evolved during the last 10,000 years. PhD advertisements to come!
Press release below with one of the few good photos of me.
Press release below with one of the few good photos of me.
| UCD Research
www.ucd.ie
September 4, 2025 at 10:14 AM
Second craziest thing you'll read today: from 2026 I will be leading an @erc.europa.eu Starter Grant project. HERDPATH will explore how livestock and their pathogens co-evolved during the last 10,000 years. PhD advertisements to come!
Press release below with one of the few good photos of me.
Press release below with one of the few good photos of me.
Reposted by Iseult
Shameless promotion from #isba11 - I'll be hiring PhDs to start early 2026 (plus postdocs starting later), using #adna to study livestock and pathogen coevolution, particularly looking at inbreeding and immune gene evolution!
Contact me at kevin[at]palaeome.org, full ad to come. Please share!
Contact me at kevin[at]palaeome.org, full ad to come. Please share!
August 27, 2025 at 3:44 PM
Reposted by Iseult
Turns out imputation of introgressed archaic regions in aDNA works really well — sometimes even better than for the rest of the genome. More on this (and other cool results) in our new preprint 👇 #aDNA #ArchaicIntrogression #imputation
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Archaic ancestry inference in imputed ancient human genomes
When modern humans expanded from Africa into Eurasia, they interbred with archaic hominins such as Neanderthals and Denisovans. This groundbreaking discovery, made in part possible through the genomic...
doi.org
July 24, 2025 at 11:12 AM
Turns out imputation of introgressed archaic regions in aDNA works really well — sometimes even better than for the rest of the genome. More on this (and other cool results) in our new preprint 👇 #aDNA #ArchaicIntrogression #imputation
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Reposted by Iseult
Excited to announce our paper on ancient Borrelia genomes is finally out! 🦠💀We document the evolutionary history of louse-borne relapsing fever, published today in @science.org with @lucyvandorp.bsky.social and @pontus-skoglund.bsky.social #aDNA 🏺🧪🧬
Main findings and paper below: 🧵⬇️
Main findings and paper below: 🧵⬇️
May 22, 2025 at 6:21 PM
Excited to announce our paper on ancient Borrelia genomes is finally out! 🦠💀We document the evolutionary history of louse-borne relapsing fever, published today in @science.org with @lucyvandorp.bsky.social and @pontus-skoglund.bsky.social #aDNA 🏺🧪🧬
Main findings and paper below: 🧵⬇️
Main findings and paper below: 🧵⬇️
Reposted by Iseult
Reposted by Iseult
The UK's political and media class has spent years heaping sadism on trans people, and they want to do the same in Ireland next. Calls for civility and calm won't cut it. We need to fight them tooth and nail.
www.irishexaminer.com/lifestyle-co...
www.irishexaminer.com/lifestyle-co...
Séamas O'Reilly: Trans people have spent a decade being attacked in a moral panic
The poor provision of unisex children’s facilities— which reinforces gender stereotypes and inconveniences women and men both — was, incidentally, an issue I remember being quite talked-about a decade...
www.irishexaminer.com
April 26, 2025 at 9:54 AM
The UK's political and media class has spent years heaping sadism on trans people, and they want to do the same in Ireland next. Calls for civility and calm won't cut it. We need to fight them tooth and nail.
www.irishexaminer.com/lifestyle-co...
www.irishexaminer.com/lifestyle-co...
Reposted by Iseult
The way the algorithms keep us hemmed into a handful of news stories has really been bothering me recently www.irishtimes.com/opinion/2025...
Patrick Freyne: Returning home from Chad, I feel there’s a glitch in western empathy
The Sudan war is the world’s biggest humanitarian disaster, but it seems our human compassion is taken up by other conflicts
www.irishtimes.com
April 24, 2025 at 8:04 AM
The way the algorithms keep us hemmed into a handful of news stories has really been bothering me recently www.irishtimes.com/opinion/2025...
Reposted by Iseult
🐐 New preprint out with @gingerhowley.bsky.social The VarGoats Consortium and many others!
We explore how genotype imputation can enhance low-coverage ancient goat/Capra🐐 genomes, shedding light on early domestication and herd management.
www.biorxiv.org/content/10.1...
#aDNA #Domestication
We explore how genotype imputation can enhance low-coverage ancient goat/Capra🐐 genomes, shedding light on early domestication and herd management.
www.biorxiv.org/content/10.1...
#aDNA #Domestication
Inferring domestic goat demographic history through ancient genome imputation
Goats were among the earliest managed animals, making them a natural model to explore the genetic consequences of domestication. However, a challenge in ancient genomic analysis is the relatively low ...
www.biorxiv.org
April 21, 2025 at 1:15 PM
🐐 New preprint out with @gingerhowley.bsky.social The VarGoats Consortium and many others!
We explore how genotype imputation can enhance low-coverage ancient goat/Capra🐐 genomes, shedding light on early domestication and herd management.
www.biorxiv.org/content/10.1...
#aDNA #Domestication
We explore how genotype imputation can enhance low-coverage ancient goat/Capra🐐 genomes, shedding light on early domestication and herd management.
www.biorxiv.org/content/10.1...
#aDNA #Domestication
Reposted by Iseult
#AncientMetagenomeDir is expanding to include C14 dating & detailed archaeological/historical info for all samples! 📜✨
🗓️ Join our Hackathon on April 29th from 10-17 CEST and contribute to this groundbreaking project! 🙌
🗓️ Join our Hackathon on April 29th from 10-17 CEST and contribute to this groundbreaking project! 🙌
April 14, 2025 at 5:25 PM
#AncientMetagenomeDir is expanding to include C14 dating & detailed archaeological/historical info for all samples! 📜✨
🗓️ Join our Hackathon on April 29th from 10-17 CEST and contribute to this groundbreaking project! 🙌
🗓️ Join our Hackathon on April 29th from 10-17 CEST and contribute to this groundbreaking project! 🙌
Reposted by Iseult
🚨 New release of #AncientMetagenomeDir! (v25.03.0, Historic Centre of Cordoba)
github.com/SPAAM-commun...
It is a community resource of #metadata of >2K shotgun-sequenced #AncientMetagenome or ancient microbial genome enriched samples & >5K libraries. Stats below (🧵 1/5)
github.com/SPAAM-commun...
It is a community resource of #metadata of >2K shotgun-sequenced #AncientMetagenome or ancient microbial genome enriched samples & >5K libraries. Stats below (🧵 1/5)
Release v25.03: Historic Centre of Cordoba · SPAAM-community/AncientMetagenomeDir
Release v25.03.0 includes 8 new publications, representing 132 new ancient host-associated metagenome samples, 33 new ancient microbial genomes, and 0 new ancient environmental samples. This brings...
github.com
April 9, 2025 at 4:00 AM
🚨 New release of #AncientMetagenomeDir! (v25.03.0, Historic Centre of Cordoba)
github.com/SPAAM-commun...
It is a community resource of #metadata of >2K shotgun-sequenced #AncientMetagenome or ancient microbial genome enriched samples & >5K libraries. Stats below (🧵 1/5)
github.com/SPAAM-commun...
It is a community resource of #metadata of >2K shotgun-sequenced #AncientMetagenome or ancient microbial genome enriched samples & >5K libraries. Stats below (🧵 1/5)
Reposted by Iseult
I'm beyond excited to share our new paper in Nature! We sequenced the first ancient human autosomal genomes from the Central Sahara, two ~7,000-year-old individuals from Takarkori in Libya, revealing a long-isolated North African lineage: www.nature.com/articles/s41...
Here's a short thread: (1/n)
Here's a short thread: (1/n)
Ancient DNA from the Green Sahara reveals ancestral North African lineage - Nature
Pastoralism spread through cultural diffusion into the Green Sahara, where an isolated, distinct North African ancestry persisted.
www.nature.com
April 2, 2025 at 4:37 PM
I'm beyond excited to share our new paper in Nature! We sequenced the first ancient human autosomal genomes from the Central Sahara, two ~7,000-year-old individuals from Takarkori in Libya, revealing a long-isolated North African lineage: www.nature.com/articles/s41...
Here's a short thread: (1/n)
Here's a short thread: (1/n)
Reposted by Iseult
🎓 PhD Position Available in the Population and Evolutionary Genetics group at Trinity College Dublin ☘️ . More details👇
March 27, 2025 at 3:31 PM
🎓 PhD Position Available in the Population and Evolutionary Genetics group at Trinity College Dublin ☘️ . More details👇
Reposted by Iseult
Interested in human-pig-boar interactions? Read our new paper on human-pig-boar relationships in Neolithic Europe 🐷🐗🧬.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Archaeogenomic insights into commensalism and regional variation in pig management in Neolithic northwest Europe | PNAS
The relationship between humans and pigs has changed dramatically since their domestication
in southwest Asia and subsequent human-induced introduc...
www.pnas.org
March 18, 2025 at 8:39 AM
Interested in human-pig-boar interactions? Read our new paper on human-pig-boar relationships in Neolithic Europe 🐷🐗🧬.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by Iseult
How did Europe's first farmers interact with their pigs and local wild boar? @jolijnerven.bsky.social has a new paper addressing just that using 11 ancient suis genomes!
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Archaeogenomic insights into commensalism and regional variation in pig management in Neolithic northwest Europe | PNAS
The relationship between humans and pigs has changed dramatically since their domestication
in southwest Asia and subsequent human-induced introduc...
www.pnas.org
March 18, 2025 at 5:23 AM
How did Europe's first farmers interact with their pigs and local wild boar? @jolijnerven.bsky.social has a new paper addressing just that using 11 ancient suis genomes!
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by Iseult
We really want this to be an event that ECRs can share their research in front of a friendly audience of other animal palaeogenomics enthusiasts. Please, the more weird and wonderful the submissions the better! #aDNA
Abstract submission is open for the online #AaRConference! Join us and invited speakers Laurent Frantz and Evon Hekkala on May 30th to present your research about animal #aDNA and discuss them with the community. All topics #aDNA related are welcomed! 🧪🧬🏺
February 11, 2025 at 7:20 PM
We really want this to be an event that ECRs can share their research in front of a friendly audience of other animal palaeogenomics enthusiasts. Please, the more weird and wonderful the submissions the better! #aDNA
Reposted by Iseult
Finally getting some of my research for my PhD out there! Hopefully soon in a journal near you ;)
Ancient Y. pestis infection from a sheep falls on the LNBA lineage, previously only known from humans! +molecular evolutionary analysis to leverage the ever increasing number of ancient genomes known!
Ancient Y. pestis infection from a sheep falls on the LNBA lineage, previously only known from humans! +molecular evolutionary analysis to leverage the ever increasing number of ancient genomes known!
Many zoonotic diseases are believed to have emerged during prehistory, but can we actually identify their past host range using ancient DNA? In the first publication of the Key Lab we present a 4000y old Yersinia pestis genome reconstructed from domesticated sheep. 🧵 www.biorxiv.org/content/10.1...
Bronze Age Yersinia pestis genome from sheep sheds light on hosts and evolution of a prehistoric plague lineage
Most human pathogens are of zoonotic origin. Many emerged during prehistory, coinciding with domestication providing more opportunities for spillover from original host species. However, we lack direc...
www.biorxiv.org
February 10, 2025 at 5:18 PM
Finally getting some of my research for my PhD out there! Hopefully soon in a journal near you ;)
Ancient Y. pestis infection from a sheep falls on the LNBA lineage, previously only known from humans! +molecular evolutionary analysis to leverage the ever increasing number of ancient genomes known!
Ancient Y. pestis infection from a sheep falls on the LNBA lineage, previously only known from humans! +molecular evolutionary analysis to leverage the ever increasing number of ancient genomes known!
Reposted by Iseult
“So why would I go through the pretense of peer review if the process is ultimately outsourced to an algorithm? I do not care for the aesthetics of peer review. We are not children playing academics. We are supposed to be doing substantive, not performative work.”
We finally got a ChatGPT generated review on a manuscript. So I wrote about how we handle these reviews is a sign of whether we have given up on peer review altogether.
Vol. 24 - Here is a revised version of your review with improved clarity
ChatGPT is not my peer. It should not review my papers.
buttondown.com
February 10, 2025 at 2:44 PM
“So why would I go through the pretense of peer review if the process is ultimately outsourced to an algorithm? I do not care for the aesthetics of peer review. We are not children playing academics. We are supposed to be doing substantive, not performative work.”
Reposted by Iseult
Very cool work on recent demographic history in Ireland and Britain - congratulations Ashwini Shanmugam and Ross Byrne!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A genetic perspective on the recent demographic history of Ireland and Britain - European Journal of Human Genetics
European Journal of Human Genetics - A genetic perspective on the recent demographic history of Ireland and Britain
www.nature.com
February 5, 2025 at 4:30 PM
Very cool work on recent demographic history in Ireland and Britain - congratulations Ashwini Shanmugam and Ross Byrne!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Iseult
Thread and open access version to come-
Ancient genomics and the origin, dispersal, and development of domestic sheep | Science search.app/gtSKYHF5HqRa...
#adna
Ancient genomics and the origin, dispersal, and development of domestic sheep | Science search.app/gtSKYHF5HqRa...
#adna
Ancient genomics and the origin, dispersal, and development of domestic sheep
The origins and prehistory of domestic sheep (Ovis aries) are incompletely understood; to address this, we generated data from 118 ancient genomes spanning 12,000 years sampled from across Eurasia. Ge...
search.app
January 30, 2025 at 7:09 PM
Thread and open access version to come-
Ancient genomics and the origin, dispersal, and development of domestic sheep | Science search.app/gtSKYHF5HqRa...
#adna
Ancient genomics and the origin, dispersal, and development of domestic sheep | Science search.app/gtSKYHF5HqRa...
#adna
Reposted by Iseult
Delighted that our new paper on female-centred kinship in Celtic Britain is out in Nature
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com
January 15, 2025 at 4:59 PM
Delighted that our new paper on female-centred kinship in Celtic Britain is out in Nature
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Iseult
I am very happy to share our new paper on the genetics of some of the first modern humans who ever lived in Europe! We sequenced nuclear DNA from 13 specimens from Ranis in Germany, and found that they belonged to at least 6 individuals. www.nature.com/articles/s41... (1/n)
Earliest modern human genomes constrain timing of Neanderthal admixture - Nature
Nature - Earliest modern human genomes constrain timing of Neanderthal admixture
www.nature.com
December 12, 2024 at 7:00 PM
I am very happy to share our new paper on the genetics of some of the first modern humans who ever lived in Europe! We sequenced nuclear DNA from 13 specimens from Ranis in Germany, and found that they belonged to at least 6 individuals. www.nature.com/articles/s41... (1/n)