Irene Serra Hueto
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ireneserrahu.bsky.social
Irene Serra Hueto
@ireneserrahu.bsky.social
Posdoctoral researcher @karalis-lab.bsky.social at the Paris Brain Institute

Thinking about how neuron-astrocyte interactions modulate circuits and cognition.
Pinned
Extremely proud to finally be able to present this work in the open🍾✨ We identify and manipulate astrocytic calcium-dependent ensembles in the NAc ✨✨ It gathers new tools, intense experiments and results that blowed our minds in the process at Navarrete's lab 🤯 Check it out! rdcu.be/d8qJi
Astrocyte ensembles manipulated with AstroLight tune cue-motivated behavior
Nature Neuroscience - Using the AstroLight system, the authors reveal that astrocytic ensembles in the nucleus accumbens regulate cue-motivated reward behavior, demonstrating that selective...
rdcu.be
Reposted by Irene Serra Hueto
I'm excited to share my latest publication! 🚨
Global and local nature of cortical slow waves:
www.cell.com/iscience/ful...

In brief, we explored in silico how cortical slow waves are shaped by both external inputs and intrinsic properties of neuronal populations.
Global and local nature of cortical slow waves
Explaining the macroscopic activity of a neuronal population from its microscopic properties poses a great challenge, not just because of the many local agents that play a role, but due to the impact ...
www.cell.com
July 29, 2025 at 10:13 AM
Reposted by Irene Serra Hueto
Thought this would be a nice way to enter the bsky community👇Delighted for Katie (now in Chris Dulla's lab at Tufts). Thank you to our collaborators, to the reviewers and to Cagla Eroglu for the highlight!
www.science.org/doi/10.1126/...
Norepinephrine signals through astrocytes to modulate synapses
Locus ceruleus (LC)–derived norepinephrine (NE) drives network and behavioral adaptations to environmental saliencies by reconfiguring circuit functional connectivity, but the underlying synapse-level...
www.science.org
May 16, 2025 at 4:34 AM
Reposted by Irene Serra Hueto
And off we go!

First talk of the 1st #ParisCircuitDynamics conference by Prof. David Dupret on how neuronal assemblies make memories!
April 28, 2025 at 9:16 AM
Moving to Paris to start a postdoc in the Neuronal Circuits and Brain Dynamics lab joining the amazing team of @nikolaskaralis.bsky.social

Great people and cool science awaits, I am excited and grateful in equal parts... @karalis-lab.bsky.social, INSERM and Paris Brain Institute here we go ✈️😊
March 16, 2025 at 2:24 PM
Reposted by Irene Serra Hueto
An #astrocytic ensemble that emerges in the nucleus accumbens upon activity during cue-motivated behaviors and is essential for modulating cue-reward associations 🧪🧪

www.nature.com/articles/s41...
Astrocyte ensembles manipulated with AstroLight tune cue-motivated behavior - Nature Neuroscience
Using the AstroLight system, the authors reveal that astrocytic ensembles in the nucleus accumbens regulate cue-motivated reward behavior, demonstrating that selective manipulation of tagged astrocyte...
www.nature.com
February 3, 2025 at 4:26 PM
Extremely proud to finally be able to present this work in the open🍾✨ We identify and manipulate astrocytic calcium-dependent ensembles in the NAc ✨✨ It gathers new tools, intense experiments and results that blowed our minds in the process at Navarrete's lab 🤯 Check it out! rdcu.be/d8qJi
Astrocyte ensembles manipulated with AstroLight tune cue-motivated behavior
Nature Neuroscience - Using the AstroLight system, the authors reveal that astrocytic ensembles in the nucleus accumbens regulate cue-motivated reward behavior, demonstrating that selective...
rdcu.be
February 3, 2025 at 12:17 PM
What a best way to enter here than with the extremely beautiful and special day that was last Friday. Now I'm a Doctor :)

PhD ends and new exciting chapters will start... I can't wait!
February 2, 2025 at 8:34 AM