Irene Ghobrial
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ireneghobrial.bsky.social
Irene Ghobrial
@ireneghobrial.bsky.social
Physician Scientist. Interested in early detection and interception in myeloma.
Reposted by Irene Ghobrial
#ASH24 myeloma, 16/27 patients were successfully tested with WGS on circulating tumor cells. Major question is how much drop out might exist. Still a tour de force by the @ireneghobrial.bsky.social lab
December 8, 2024 at 6:58 PM
Reposted by Irene Ghobrial
Watch as @ireneghobrial.bsky.social @danafarber.bsky.social dives into groundbreaking insights from longitudinal single-cell studies & #teclistamab outcomes at #ASH24 🎥

Don't miss this #VJHemOnc interview 👉 tinyurl.com/3u7dkrhn

@ash-hematology.bsky.social #MultipleMyeloma #MMsm
December 9, 2024 at 8:04 PM
Decentralized clinical trials. Amazing collaboration with pharma and FDA and academia with ash. #ash24
December 6, 2024 at 10:06 PM
Reposted by Irene Ghobrial
8 days ago, ASH decided to join Bluesky. 🌤️ So far, we're enjoying fewer distractions & more meaningful connections. 💬 Engaging with our amazing #hematology and #hemeonc communities has never been easier.

We created an #ASH24 feed for you & we have more feeds coming soon: bit.ly/ASH24feed

#Hemesky
November 29, 2024 at 7:46 PM
Reposted by Irene Ghobrial
A 1,000-Genome Map for Multiple Myeloma and Its Precursor Stages, and Its Impact on Clinical Outcome [Dec 9, 2024] Alberge et al. @IrenemGhobrial #ASH24 Abst 1019 ash.confex.com/ash/2024/web... #mmsm #cagenome #PrecisionMedicine
Paper: A 1,000-Genome Map for Multiple Myeloma and Its Precursor Stages, and Its Impact on Clinical Outcome
ash.confex.com
November 26, 2024 at 4:59 PM
Reposted by Irene Ghobrial
1/ Keen to share the story of my postdoc research out in @natureportfolio.bsky.social! We built a massive resource characterizing the spatial landscape of the gut—and yes, we dug deep into the biology too. If you’ve got a minute, let me walk you through the story. 🧵👇
www.nature.com/articles/s41...
Spatially restricted immune and microbiota-driven adaptation of the gut - Nature
Intestinal regionalization is characterized by robust and resilient structural cell states and the intestine can adapt to environmental stress in a spatially controlled manner through crosstalk betwee...
www.nature.com
November 21, 2024 at 10:21 PM
Reposted by Irene Ghobrial
Throwback to the editorial we wrote last year celebrating the Ig Nobels.

Free-to-read link: rdcu.be/d09QN
November 22, 2024 at 4:07 PM
Reposted by Irene Ghobrial
This week, Nature Portfolio published a series of research papers from the Human Cell Atlas initiative. Nature profiles some of the key technologies that made them possible. 🧪
Computational technologies of the Human Cell Atlas
As the international effort reaches a ‘critical mass’ of achievements, Nature highlights seven tools that are poised to enable the next set of discoveries.
go.nature.com
November 23, 2024 at 3:03 PM
Reposted by Irene Ghobrial
Out today in Nature: "The Human Cell Atlas"! In my News and Views, I compare the cell atlas to early naturalists creating an atlas of South America. Researchers mining this cell atlas can now make big discoveries, just as the next naturalists then discovered evolution.
www.nature.com/articles/d41...
November 20, 2024 at 5:07 PM
Reposted by Irene Ghobrial
The Human Cell Atlas Consortia just released its initial efforts in a series of articles. #MedSky #ScienceSky

www.nature.com/immersive/d4...
November 21, 2024 at 12:44 PM
Reposted by Irene Ghobrial
Excellent open-access #MMsm work in @AjHematology by Zabaleta @BrunoPaiva_UNAV et al!

An important footnote for all the CAR-T vs bsAb efficacy debates: when stratified by MRD status, CAR-T and bsAbs do identically.

Getting to MRD neg is what matters!

onlinelibrary.wiley.com/doi/10.1002/...
November 17, 2024 at 2:26 AM