Isabelle Miousse
imiousse.bsky.social
Isabelle Miousse
@imiousse.bsky.social
Scientist studying one-carbon metabolism
Most of us never get ANY formal training in writing reference letters, yet they are so important for our colleagues and students (and ourselves!). We assembled a panel of experts from academia, government and industry to answer your questions
Join us for a new #EMGS webinar, "The Art of Advocacy: Crafting Persuasive Letters," hosted by the Women in the EMGS SIG on June 25th!

Register Now: emgs-us.org/event/EMGSWE...
June 24, 2025 at 1:57 PM
This is worth a few minutes of your time
NIH’s new director Jay Bhattacharya discusses staff morale, grant cuts, and “rumors” in an interview with Science. scim.ag/4mhSMpA
‘It’s been a tough period’: NIH’s new director speaks with Science
Jay Bhattacharya discusses staff morale, grant cuts, and “rumors”
scim.ag
May 6, 2025 at 8:44 PM
Check out my new publication in journals.physiology.org
on #ozempic and #cancer. GLP-1 receptor agonists are fundamentally a type of caloric restriction and we predict strong anti-cancer effects in diabetics. But what about cachexia? journals.physiology.org/doi/abs/10.1...
GLP-1 Receptor Agonists in the Context of Cancer – The Road Ahead | American Journal of Physiology-Cell Physiology | American Physiological Society
A rapidly increasing proportion of the population in the United State is taking Glucagon-Like Peptide-1 receptor agonists (GLP-1RAs) for type 2 diabetes (T2D) or weight loss. Consequently, an increasi...
journals.physiology.org
April 28, 2025 at 3:02 PM
Wow! There's so much science left to do in the world 🤯https://www.nature.com/articles/d41586-025-01269-8?utm_source=Live+Audience&utm_campaign=8a74680f93-nature-briefing-daily-20250424&utm_medium=email&utm_term=0_b27a691814-8a74680f93-50001960
Century-old genetics mystery of Mendel’s peas finally solved
Researchers pinpoint the genes responsible for the final three pea traits studied by the famed citizen scientist.
www.nature.com
April 24, 2025 at 6:48 PM
Good summary of the last week in science policy. I feel a bit more caught up now
www.science.org/content/arti...
New NIH director defends grant cuts as part of shift to support MAHA vision
In his first public remarks, Bhattacharya emphasizes his overall support for agency
www.science.org
April 22, 2025 at 8:03 PM
Reposted by Isabelle Miousse
If you have a lost NSF or NIH grant. Colleagues inside government agencies are tracking terminated grants in hopes of assisting organizing efforts and perhaps litigation. The link takes you to the NSF tracker; the NIH tracker is linked from there. Pass this on. 🧪🥼

airtable.com/appGKlSVeXni...
April 20, 2025 at 6:39 PM
Let me introduce my home town, Jonquière in Saguenay-Lac-Saint-Jean. That’s where a big part of the aluminum for cars production is from, thanks to tons of available hydro power. natural-resources.canada.ca/minerals-min...
Aluminum facts - Natural Resources Canada
Aluminum is a lightweight, durable, flexible, and non-corrosive metal that is infinitely recyclable, making it one of the most widely used and recycled metals in the world.
natural-resources.canada.ca
March 29, 2025 at 2:42 PM
Reposted by Isabelle Miousse
Gaps may be small, but the meeting will be big! Come join us in South Korea!
DNA Replication Gaps, Cancer and Disease Meeting Promo
Join us at the Keystone Symposia on DNA Replication Gaps, Cancer and Disease, April 27-30, 2025, in Daejeon, South Korea with field leaders in DNA replication errors, DNA breaks, DNA repair and cancer! http://keysym.us/KSDNARep25 #KSDNARep25 IMPORTANT DEADLINES: Early Registration Deadline (Save $200): March 11, 2025 Poster Abstract Deadline: April 3, 2025 ___ Copyright Keystone Symposia, 2025. All rights reserved. About Keystone Symposia: Keystone Symposia is a 501(c)(3) nonprofit organization founded in 1972 that convenes 50-60 open, international scientific research conferences each year across the full range of the life sciences – from cardiovascular disease to immunology to neurobiology. The conferences accelerate life science discovery by bringing together and fostering collaboration among the world’s leading and next generation of research scientists. Visit Keystone Symposia at: https://www.keystonesymposia.org Visit Virtual Keystone Symposia at: https://virtual.keystonesymposia.org/ For more videos: https://www.youtube.com/user/KeystoneSymposia Follow us on Twitter: https://twitter.com/keystonesymp Follow us on BlueSky: https://bsky.app/profile/keystonesymposia.bsky.social Like us on Facebook: https://www.facebook.com/KeystoneSymposia Link to us on LinkedIn: https://www.linkedin.com/company/keystone-symposia-on-molecular-and-cellular-biology
nam10.safelinks.protection.outlook.com
March 7, 2025 at 3:18 AM
The UAMS Cancer Institute is hosting Dr. Patricia Opresko @opreskolab.bsky.social on Monday at noon for the Forum Speaker Series. Don't miss it!
March 6, 2025 at 10:39 PM
Reposted by Isabelle Miousse
Happy #WomensHistoryMonth and #InternationalWomensDay from the #EMGS! Did you know #EMGS has a Special Interest Group for #Women in EMGS?

Learn more here: emgs-us.org/page/wemgs

Chaired by @i_miousse! #WomenInSTEM #WomenInScience
Women in the EMGS SIG - Environmental Mutagenesis and Genomics Society
The mission of the Women in EMGS (WEMGS) Special Interest Group (SIG) is to provide a forum for discussion on the specific challenges faced by women in our society, a place for EMGS members of any sex interested in this topic to meet and share with one another, and an organized effort to share our experiences and support each other. Women in all fields of science have encountered barriers due to both negative stereotypes leading to being dismissed more easily as scientists, as well as societal pressures to perform more uncompensated and unrecognized work both in the workplace and at home. For both sexes, expectations in science have been at odds with the fulfillment of responsibilities outside of work (e.g. caregiving) and the nurturing of healthy and meaningful human relationships.The main event sponsored by WEMGS is a luncheon at the annual EMGS meeting. This luncheon may feature, for example, an invited speaker or a group discussion. Relevant activities of this SIG may also include, but are not limited to, planning and sponsoring symposia, platform sessions, breakfast meetings, social events, and workshops for the EMGS Annual Meeting, and updating members about the latest news through the EMGS website and email forum. Overall, this SIG provides a platform for members from all sectors (academia, industry, and government agencies) to discuss issues of importance to the WEMGS members and provide support to each other.
emgs-us.org
March 5, 2025 at 2:16 PM
Some perspective. Back in the late nineties, a flawed human being successfully balanced the US budget. Did they cut research? Oh, actually, congress voted a large increase in NIH budget. www.nature.com/articles/35209 Different times...
March 4, 2025 at 9:21 PM
Reposted by Isabelle Miousse
Exciting new preprint led by @glowingtelomeres.bsky.social reveals how 6-thio-dG (THIO drug) targets telomeres in cancers. This drug “traps” telomerase in a non-productive state to prevent telomere lengthening and cancer cell growth. www.biorxiv.org/content/10.1...
Chemotherapeutic 6-thio-2’-deoxyguanosine selectively targets and inhibits telomerase by inducing a non-productive telomere-bound telomerase complex
Most cancers upregulate the telomere lengthening enzyme telomerase to achieve unlimited cell division. How chemotherapeutic nucleoside 6-thio-2’-deoxyguanosine (6-thio-dG) targets telomerase to inhibi...
www.biorxiv.org
March 3, 2025 at 6:34 PM
Study section SEP-8: NCI CLINICAL AND TRANSLATIONAL CANCER RESEARCH was held on schedule today. With all the cancellations going on, I thought it was worth mentioning
February 25, 2025 at 11:14 PM
What's wrong with the world! How dare you impersonate Tim Hortons, hothanhtam0801@gmail.com !
February 20, 2025 at 6:01 PM
Reposted by Isabelle Miousse
So a former postdoc from our department had just started as a PO at NIH and was terminated in the wave of terminations last week. He is in the research triangle and a phenomenal scientist with expertise in stress and glia. If anyone in the RTI is hiring asap please let me know! #neuroskyence
February 16, 2025 at 9:46 PM
I will spend a few days in Canada. It will do me some good
February 8, 2025 at 2:34 AM
Congratulations to @emgsus.bsky.social member Erik Larson for his new study in @naturecomms.bsky.social about the role of DNA breaks at G-quadruplexes in polycystic kidney disease pubmed.ncbi.nlm.nih.gov/39747084/
G-quadruplex stabilization provokes DNA breaks in human PKD1, revealing a second hit mechanism for ADPKD - PubMed
The "secondhit" pathway is responsible for biallelic inactivation of many tumor suppressors, where a pathogenic germline allele is joined by somatic mutation of the remaining functional allele. The me...
pubmed.ncbi.nlm.nih.gov
January 29, 2025 at 6:13 PM
I did my fair share of cold emails for my postdoc. I would always start with "I am relocating to Little Rock", which was 1-True, and 2- An excellent way to get people's attention. I would also suggest to use a .edu email if at all possible
www.nature.com/articles/d41...
Four tips for writing the perfect ‘cold e-mail’ in job applications
These strategies can transform your unsolicited applications from forgettable to fabulous.
www.nature.com
January 27, 2025 at 7:19 PM
Elephants are probably not people, but they are 100% more people than corporations!
bbc.com/news/article...
Elephants are not people, rules Colorado Supreme Court
Judges ruled a bid to free five elderly African elephants from Cheyenne Mountain Zoo was based on a law that only applied to humans.
bbc.com
January 22, 2025 at 7:28 PM
Do you know what? You can get a free guided tour of the capitol building in DC by contacting your representative. No political question asked, just a dedicated staff member available to serve their constituents. My new country keeps surprising me #dualcitizen
January 3, 2025 at 4:03 PM