Cantorlab
@cantorlab.bsky.social
Our lab studies ssDNA gaps as the cause of BRCAness and investigates how these gaps create a therapeutic window for sensitizing cancer cells to anti-cancer therapies.
Reposted by Cantorlab
Happy to share a new publication on Mechanistic Coupling of Enzyme Activities at the Replisome in JBC. We #Traklab compare and contrast strategies used across organisms to coordinate the many enzymatic processes that occur during DNA replication. Hope it is helpful. doi.org/10.1016/j.jb...
October 24, 2025 at 6:12 PM
Happy to share a new publication on Mechanistic Coupling of Enzyme Activities at the Replisome in JBC. We #Traklab compare and contrast strategies used across organisms to coordinate the many enzymatic processes that occur during DNA replication. Hope it is helpful. doi.org/10.1016/j.jb...
Enjoying Brisbane from TRI seminar to Felons brewery with Kum Kum Khanna and MathewJones.
October 25, 2025 at 4:17 AM
Enjoying Brisbane from TRI seminar to Felons brewery with Kum Kum Khanna and MathewJones.
Reposted by Cantorlab
9 days to go:
* 2 x open positions!
* Exceptional environment, competitive start-up package
* University of Toronto appointments
* Toronto has great (and peaceful) quality of life!
* 2 x open positions!
* Exceptional environment, competitive start-up package
* University of Toronto appointments
* Toronto has great (and peaceful) quality of life!
JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.
www.nature.com/naturecareer...
Please repost!
www.nature.com/naturecareer...
Please repost!
October 11, 2025 at 12:40 PM
9 days to go:
* 2 x open positions!
* Exceptional environment, competitive start-up package
* University of Toronto appointments
* Toronto has great (and peaceful) quality of life!
* 2 x open positions!
* Exceptional environment, competitive start-up package
* University of Toronto appointments
* Toronto has great (and peaceful) quality of life!
Happy to share new work from my lab by co-authors Peng and Lee-when BRCA1 is absent, RAD51 is busy authors.elsevier.com/sd/article/S...
September 10, 2025 at 5:32 PM
Happy to share new work from my lab by co-authors Peng and Lee-when BRCA1 is absent, RAD51 is busy authors.elsevier.com/sd/article/S...
UMASS Graduation-Congratulations Silvia!
June 2, 2025 at 10:08 PM
UMASS Graduation-Congratulations Silvia!
Reposted by Cantorlab
Wrapping up an insightful conference on DNA Replication Gaps, Cancer, and Disease! 🎉 Congrats to our Future of Science Fund winners, Larissa Milano and @seppai99.bsky.social! Your achievements inspire us. 🌟 #KSDNARep25 @cantorlab.bsky.social @albertociccia.bsky.social @labvincenzo.bsky.social
April 30, 2025 at 5:08 PM
Wrapping up an insightful conference on DNA Replication Gaps, Cancer, and Disease! 🎉 Congrats to our Future of Science Fund winners, Larissa Milano and @seppai99.bsky.social! Your achievements inspire us. 🌟 #KSDNARep25 @cantorlab.bsky.social @albertociccia.bsky.social @labvincenzo.bsky.social
Three days, fresh data, & sparkly debates on how replication gaps drive cancer & disease. Grateful for every talk & discussion. Thank you for pushing science forward—next stop: great papers. Science moves fast when we move together! @albertociccia.bsky.social @labvincenzo.bsky.social
May 2, 2025 at 8:26 AM
Three days, fresh data, & sparkly debates on how replication gaps drive cancer & disease. Grateful for every talk & discussion. Thank you for pushing science forward—next stop: great papers. Science moves fast when we move together! @albertociccia.bsky.social @labvincenzo.bsky.social
Looking forward to reading!
Excited to share our new pre-print. Direct, ensemble FRET assays developed by our lab reveal that assembly of Rad51 filaments at stalled replication sites via RPA/Rad51 exchange causes complete & irreversible PCNA unloading. Big implications for interplay between human DNA damage tolerance pathways
www.biorxiv.org
April 2, 2025 at 2:33 AM
Looking forward to reading!
Reposted by Cantorlab
Submit poster abstracts by 4/3, 11:59pm MST for DNA Replication Gaps, Cancer, and Disease in Daejeon, South Korea. Join experts to explore DNA errors and cancer. keysym.us/KSDNARep25.
youtu.be/_aPIkDQg1rw #KSDNARep25 @cantorlab.bsky.social @albertociccia.bsky.social @labvincenzo.bsky.social
youtu.be/_aPIkDQg1rw #KSDNARep25 @cantorlab.bsky.social @albertociccia.bsky.social @labvincenzo.bsky.social
KSQA: Dr. Kyungjae Myung (DNA Replication Gaps)
YouTube video by KeystoneSymposia
youtu.be
March 27, 2025 at 6:37 PM
Submit poster abstracts by 4/3, 11:59pm MST for DNA Replication Gaps, Cancer, and Disease in Daejeon, South Korea. Join experts to explore DNA errors and cancer. keysym.us/KSDNARep25.
youtu.be/_aPIkDQg1rw #KSDNARep25 @cantorlab.bsky.social @albertociccia.bsky.social @labvincenzo.bsky.social
youtu.be/_aPIkDQg1rw #KSDNARep25 @cantorlab.bsky.social @albertociccia.bsky.social @labvincenzo.bsky.social
Reposted by Cantorlab
Our latest article, in collaboration with Helle Ulrich, explores how the timing of lesion bypass and gap processing impacts genome stability.
doi.org/10.1093/nar/...
doi.org/10.1093/nar/...
March 24, 2025 at 10:42 AM
Our latest article, in collaboration with Helle Ulrich, explores how the timing of lesion bypass and gap processing impacts genome stability.
doi.org/10.1093/nar/...
doi.org/10.1093/nar/...
Gaps may be small, but the meeting will be big! Come join us in South Korea!
DNA Replication Gaps, Cancer and Disease Meeting Promo
Join us at the Keystone Symposia on DNA Replication Gaps, Cancer and Disease, April 27-30, 2025, in Daejeon, South Korea with field leaders in DNA replication errors, DNA breaks, DNA repair and cancer! http://keysym.us/KSDNARep25 #KSDNARep25 IMPORTANT DEADLINES: Early Registration Deadline (Save $200): March 11, 2025 Poster Abstract Deadline: April 3, 2025 ___ Copyright Keystone Symposia, 2025. All rights reserved. About Keystone Symposia: Keystone Symposia is a 501(c)(3) nonprofit organization founded in 1972 that convenes 50-60 open, international scientific research conferences each year across the full range of the life sciences – from cardiovascular disease to immunology to neurobiology. The conferences accelerate life science discovery by bringing together and fostering collaboration among the world’s leading and next generation of research scientists. Visit Keystone Symposia at: https://www.keystonesymposia.org Visit Virtual Keystone Symposia at: https://virtual.keystonesymposia.org/ For more videos: https://www.youtube.com/user/KeystoneSymposia Follow us on Twitter: https://twitter.com/keystonesymp Follow us on BlueSky: https://bsky.app/profile/keystonesymposia.bsky.social Like us on Facebook: https://www.facebook.com/KeystoneSymposia Link to us on LinkedIn: https://www.linkedin.com/company/keystone-symposia-on-molecular-and-cellular-biology
nam10.safelinks.protection.outlook.com
March 7, 2025 at 3:18 AM
Gaps may be small, but the meeting will be big! Come join us in South Korea!
I was very sad to learn of the passing of Mike Volkert, brilliant scientist always with kind smile...obit is posted www.umassmed.edu/maps/
Department of Microbiology
The Department of Microbiology was founded in 2010, and is the product of a merger between two departments, one focused on microbiology, genetics, and immunology, and the other focused on physiology.
www.umassmed.edu
January 30, 2025 at 7:25 PM
I was very sad to learn of the passing of Mike Volkert, brilliant scientist always with kind smile...obit is posted www.umassmed.edu/maps/
Congratulations to Jenna Whalen on her Nature Cancer paper out today-a distinct take on nicks and their toxicity! rdcu.be/d60Td
Targeting BRCA1-deficient PARP inhibitor-resistant cells with nickases reveals nick resection as a cancer vulnerability
Nature Cancer - Whalen et al. report that increased DNA end resection in BRCA-deficient, PARP inhibitor-resistant cancers leads to increased sensitivity to DNA nicks, limiting tumor formation in...
rdcu.be
January 21, 2025 at 5:26 PM
Congratulations to Jenna Whalen on her Nature Cancer paper out today-a distinct take on nicks and their toxicity! rdcu.be/d60Td
Please join the conversation and get your abstract in!
Join Helle D. Ulrich & experts this April to explore DNA replication errors, breaks, repair, and cancer! Submit abstracts and scholarships by Jan. 28 (11:59pm MST)! keysym.us/KSDNARep25
#KSDNARep25 #DNAreplicationgaps @cantorlab.bsky.social @albertociccia.bsky.social @labvincenzo.bsky.social
#KSDNARep25 #DNAreplicationgaps @cantorlab.bsky.social @albertociccia.bsky.social @labvincenzo.bsky.social
January 15, 2025 at 12:49 AM
Please join the conversation and get your abstract in!
Groundbreaking, first ever meeting dedicated to DNA GAPS
📅 Save the Date: April 27-30, 2025 | Daejeon, South Korea www.keystonesymposia.org/conferences/...
DNA Replication Gaps, Cancer and Disease | Keystone Symposia
Join us at the Keystone Symposia on DNA Replication Gaps, Cancer and Disease, April 2025, in Daejeon, with field leaders!
www.keystonesymposia.org
November 24, 2024 at 1:17 AM
Groundbreaking, first ever meeting dedicated to DNA GAPS
📅 Save the Date: April 27-30, 2025 | Daejeon, South Korea www.keystonesymposia.org/conferences/...