Ilyas Alav
@ilyasalav.bsky.social
Interested in the physiological role of bacterial efflux pumps and host-pathogen interactions🏳️🌈 (he/him)
https://scholar.google.com/citations?user=nhIW1SUAAAAJ&hl=en
https://scholar.google.com/citations?user=nhIW1SUAAAAJ&hl=en
Pinned
Ilyas Alav
@ilyasalav.bsky.social
· Apr 3
I am ecstatic to announce that I’ve been awarded a @wellcometrust.bsky.social Early Career Award! I couldn’t have done it without everyone who helped me along the way! I will join @dunnschool.bsky.social to do some exciting science on efflux pumps for the next 5 years!
journals.asm.org/doi/10.1128/...
My first corresponding author paper is now out in MMBR @asm.org! In this review, @csdetweiler.bsky.social and I assess the evidence for RND efflux pumps as virulence determinants in Gram-negative bacteria.
My first corresponding author paper is now out in MMBR @asm.org! In this review, @csdetweiler.bsky.social and I assess the evidence for RND efflux pumps as virulence determinants in Gram-negative bacteria.
Beyond antibiotic resistance: evidence for resistance-nodulation-division (RND) efflux pumps as virulence determinants | Microbiology and Molecular Biology Reviews
SUMMARYEarly in evolution, cells acquired the ability to use energy to export waste and toxic
products against a concentration gradient. In Gram-negative bacteria, the resistance-nodulation-cell
divis...
journals.asm.org
November 20, 2025 at 2:21 PM
journals.asm.org/doi/10.1128/...
My first corresponding author paper is now out in MMBR @asm.org! In this review, @csdetweiler.bsky.social and I assess the evidence for RND efflux pumps as virulence determinants in Gram-negative bacteria.
My first corresponding author paper is now out in MMBR @asm.org! In this review, @csdetweiler.bsky.social and I assess the evidence for RND efflux pumps as virulence determinants in Gram-negative bacteria.
Reposted by Ilyas Alav
Really excited to say that we have been awarded a BBSRC sLola! Really looking forward to kick off this project with such a fantastic team! @webberma.bsky.social @overtonlab.bsky.social @bugsinblood.bsky.social Sara Jabbari, Dong-Hyun Kim @imibirmingham.bsky.social www.ukri.org/news/powerin...
Powering team science to unlock life’s secrets
Four world-class teams awarded major BBSRC sLoLa grants to push the frontiers of discovery in microbiology, photosynthesis, gene regulation and quantum biology.
www.ukri.org
November 18, 2025 at 9:48 AM
Really excited to say that we have been awarded a BBSRC sLola! Really looking forward to kick off this project with such a fantastic team! @webberma.bsky.social @overtonlab.bsky.social @bugsinblood.bsky.social Sara Jabbari, Dong-Hyun Kim @imibirmingham.bsky.social www.ukri.org/news/powerin...
Reposted by Ilyas Alav
Did you know food-derived natural products may reveal how antimicrobial resistance plasmids spread in Enterobacterales? Celebrate World Food Day by reflecting on how our diet affects the world. Read more in Microbiology: doi.org/10.1099/mic.... #MicrobioJ #WorldFoodDay
Natural products from food sources can alter the spread of antimicrobial resistance plasmids in Enterobacterales
Antimicrobial resistance (AMR) poses a significant threat to global public health. Notably, resistance to carbapenem and extended-spectrum β-lactam antibiotics in Gram-negative bacteria is a major…
doi.org
October 16, 2025 at 7:01 AM
Did you know food-derived natural products may reveal how antimicrobial resistance plasmids spread in Enterobacterales? Celebrate World Food Day by reflecting on how our diet affects the world. Read more in Microbiology: doi.org/10.1099/mic.... #MicrobioJ #WorldFoodDay
Reposted by Ilyas Alav
New PhDs in my lab starting 2026!
Funded projects as part of the MIBTP centre (funded by BBSRC) now open for applications: warwick.ac.uk/fac/cross_fa...
Are you interested in biofilms? We have a couple of projects - looking at the links between energy metabolism and biofilms - and electricity!
Funded projects as part of the MIBTP centre (funded by BBSRC) now open for applications: warwick.ac.uk/fac/cross_fa...
Are you interested in biofilms? We have a couple of projects - looking at the links between energy metabolism and biofilms - and electricity!
Dr Tim Overton
Dr Tim Overton
warwick.ac.uk
October 14, 2025 at 8:29 AM
New PhDs in my lab starting 2026!
Funded projects as part of the MIBTP centre (funded by BBSRC) now open for applications: warwick.ac.uk/fac/cross_fa...
Are you interested in biofilms? We have a couple of projects - looking at the links between energy metabolism and biofilms - and electricity!
Funded projects as part of the MIBTP centre (funded by BBSRC) now open for applications: warwick.ac.uk/fac/cross_fa...
Are you interested in biofilms? We have a couple of projects - looking at the links between energy metabolism and biofilms - and electricity!
Reposted by Ilyas Alav
Job opportunity in my lab! We're looking for a post-doc to come join us for an exciting project exploring the evolution of #AMR and #hypervirulence in #klebsiella. Please share!! @unibirmingham.bsky.social Details: www.jobs.ac.uk/job/DOV067/r...
Research Fellow at University of Birmingham
Apply now for the Research Fellow role on jobs.ac.uk - the leading job board for higher education jobs. View details.
www.jobs.ac.uk
October 2, 2025 at 10:56 AM
Job opportunity in my lab! We're looking for a post-doc to come join us for an exciting project exploring the evolution of #AMR and #hypervirulence in #klebsiella. Please share!! @unibirmingham.bsky.social Details: www.jobs.ac.uk/job/DOV067/r...
Reposted by Ilyas Alav
Strain-dependent contribution of the AcrAB-TolC efflux pump to Klebsiella pneumoniae physiology https://www.biorxiv.org/content/10.1101/2025.09.26.678718v1
September 27, 2025 at 4:20 AM
Strain-dependent contribution of the AcrAB-TolC efflux pump to Klebsiella pneumoniae physiology https://www.biorxiv.org/content/10.1101/2025.09.26.678718v1
www.biorxiv.org/content/10.1...
New preprint of my first corresponding author research paper! This is the result of my master students and some lovely collaborators! ☺️
New preprint of my first corresponding author research paper! This is the result of my master students and some lovely collaborators! ☺️
Strain-dependent contribution of the AcrAB-TolC efflux pump to Klebsiella pneumoniae physiology
Klebsiella pneumoniae is a prominent opportunistic pathogen increasingly associated with multidrug resistance and virulence. One of the main mechanisms of antimicrobial resistance in K. pneumoniae is ...
www.biorxiv.org
September 27, 2025 at 11:00 AM
www.biorxiv.org/content/10.1...
New preprint of my first corresponding author research paper! This is the result of my master students and some lovely collaborators! ☺️
New preprint of my first corresponding author research paper! This is the result of my master students and some lovely collaborators! ☺️
My nose must be riddled with S. aureus then 🫠
#NewResearch
Nasal colonisation by S. aureus is linked with depression in a human cohort and shown in a mouse model to cause decreased serotonin and dopamine in the brain
#MicroSky #Depression
www.nature.com/articles/s41...
Nasal colonisation by S. aureus is linked with depression in a human cohort and shown in a mouse model to cause decreased serotonin and dopamine in the brain
#MicroSky #Depression
www.nature.com/articles/s41...
Nasal Staphylococcus aureus carriage promotes depressive behaviour in mice via sex hormone degradation - Nature Microbiology
Nasal colonization by Staphylococcus aureus is linked with depression in a human cohort and shown in a mouse model to cause decreased serotonin and dopamine in the brain.
www.nature.com
September 22, 2025 at 5:16 PM
My nose must be riddled with S. aureus then 🫠
This #PeerReviewWeek, I would like to thank the single reviewer who is holding up editorial decisions!
a man with a mustache is saying thank you .
ALT: a man with a mustache is saying thank you .
media.tenor.com
September 18, 2025 at 3:20 PM
This #PeerReviewWeek, I would like to thank the single reviewer who is holding up editorial decisions!
guess I should be glad my hair isn’t falling out yet
September 7, 2025 at 5:11 PM
guess I should be glad my hair isn’t falling out yet
‘good things come to those who wait’ as I say while refreshing the peer review portal page 🥰
September 4, 2025 at 5:24 PM
‘good things come to those who wait’ as I say while refreshing the peer review portal page 🥰
Which section of a paper do you hate writing the most and why is it the ‘Discussion’?
August 22, 2025 at 8:57 PM
Which section of a paper do you hate writing the most and why is it the ‘Discussion’?
waiting for peer review reports in the summer
an older woman is crying and says it 's been 84 years
ALT: an older woman is crying and says it 's been 84 years
media.tenor.com
August 14, 2025 at 5:09 PM
waiting for peer review reports in the summer
will be enjoying me 1.4% pay uplift, thank you @ucea.bsky.social 🥰
a man in a black shirt is holding up a one dollar bill
ALT: a man in a black shirt is holding up a one dollar bill
media.tenor.com
August 6, 2025 at 1:24 PM
will be enjoying me 1.4% pay uplift, thank you @ucea.bsky.social 🥰
First corresponding author manuscript submitted! 😬🤞
July 24, 2025 at 5:22 PM
First corresponding author manuscript submitted! 😬🤞
being sick with the cold in the summer is so weak 🙃
July 23, 2025 at 9:55 PM
being sick with the cold in the summer is so weak 🙃
Bought an Integra pipetboy and it came with a switch blade 🤔
July 22, 2025 at 4:25 PM
Bought an Integra pipetboy and it came with a switch blade 🤔
Has anyone done Klebsiella pneumoniae survival assay in the presence of LL-37? I’ve read several papers, but they all use different media! 😭
June 26, 2025 at 5:43 PM
Has anyone done Klebsiella pneumoniae survival assay in the presence of LL-37? I’ve read several papers, but they all use different media! 😭
Why are UK universities so hesitant to pay researchers a fair salary?
May 8, 2025 at 12:58 PM
Why are UK universities so hesitant to pay researchers a fair salary?
I am ecstatic to announce that I’ve been awarded a @wellcometrust.bsky.social Early Career Award! I couldn’t have done it without everyone who helped me along the way! I will join @dunnschool.bsky.social to do some exciting science on efflux pumps for the next 5 years!
April 3, 2025 at 10:59 AM
I am ecstatic to announce that I’ve been awarded a @wellcometrust.bsky.social Early Career Award! I couldn’t have done it without everyone who helped me along the way! I will join @dunnschool.bsky.social to do some exciting science on efflux pumps for the next 5 years!
I cook when I’m sad, so here’s Marry Me Chicken Meatballs
March 31, 2025 at 6:58 PM
I cook when I’m sad, so here’s Marry Me Chicken Meatballs
once again, i’m waiting for a career defining decision. might finally quit academia and become financially stable 😎
March 30, 2025 at 6:59 PM
once again, i’m waiting for a career defining decision. might finally quit academia and become financially stable 😎
www.nature.com/articles/s41...
I had to dig through the supplementary tables, but it is nice to see that AcrAB-TolC is also important for C. rodentium colonisation of mice.
I had to dig through the supplementary tables, but it is nice to see that AcrAB-TolC is also important for C. rodentium colonisation of mice.
Inducible transposon mutagenesis identifies bacterial fitness determinants during infection in mice - Nature Microbiology
InducTn-seq, a method for inducible mutagenesis followed by transposon insertion site sequencing, enables temporal control of transposition to bypass population bottlenecks and enable the quantificati...
www.nature.com
March 28, 2025 at 11:01 AM
www.nature.com/articles/s41...
I had to dig through the supplementary tables, but it is nice to see that AcrAB-TolC is also important for C. rodentium colonisation of mice.
I had to dig through the supplementary tables, but it is nice to see that AcrAB-TolC is also important for C. rodentium colonisation of mice.