Institute of Biotechnology
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ibtcas.bsky.social
Institute of Biotechnology
@ibtcas.bsky.social
Insight into structural, protein and cellular biology leads to new therapies.

www.ibt.cas.cz
📢 We are hiring!

• Postdoctoral Researcher in Molecular Transport Dynamics
• PhD Positions in Quantitative Imaging of Ciliary Transport
– Track A: Single-Molecule Imaging
– Track B: Imaging Technology & Method Development

📍 BIOCEV, near Prague
👉 Details via QR codes
January 29, 2026 at 6:42 PM
Little visitors, big curiosity 💛
Children from Vestec Kindergarten explored the laboratories of the Centre of Molecular Structure and discovered that science can be fun from a very young age. 🧪👀

Thank you for the visit! ✨
January 28, 2026 at 5:05 PM
Carta Genum, founded by Lukáš Valihrach and Daniel Žucha, raised pre-seed funding from Czech Founders VC and joined the Sherpa accelerator. 🧬
They aim to make biological data analysis accessible — without black-box AI or coding barriers.
👉https://1url.cz/gJy66
January 23, 2026 at 10:55 AM
✨ 𝐆𝐚𝐭𝐞𝐬 𝐨𝐟 𝐈𝐦𝐚𝐠𝐢𝐧𝐚𝐭𝐢𝐨𝐧 ✨
Mouse cerebellum captured through the lens of science and art.
🏆 December Picture of the Month
📸 Lenka Gmiterková
January 19, 2026 at 5:54 PM
Reposted by Institute of Biotechnology
A new paper🧬Bacteria sense the antibiotic rifampicin through a widespread dual-promoter based alarm system
Nucleic Acids Research (2026)
Lab of Microbial Genetics and Gene Expression IMIC, @iocbprague.bsky.social @ibtcas.bsky.social @akademievedcr.bsky.social

➡️ academic.oup.com/nar/article/...
January 15, 2026 at 11:35 AM
🧬 New Nucleic Acids Research paper: updated standards for validating RNA/DNA covalent geometry in PDB models.
Introducing a 3-tier scheme:
🟢Preferred 🟡Allowed 🔴Of Concern — to reduce false alarms & improve future deposits. 🚀
doi.org/10.1093/nar/...
New targets and procedures for validating the valence geometry of nucleic acid structures
Abstract. A Working Group consisting of the co-authors of this paper was established in 2020 to re-evaluate the standard valence geometry used for the vali
doi.org
January 12, 2026 at 2:07 PM
𝐄𝐱𝐜𝐢𝐭𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐨𝐮𝐫 𝐧𝐞𝐰 𝐍𝐮𝐜𝐥𝐞𝐢𝐜 𝐀𝐜𝐢𝐝𝐬 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐩𝐚𝐩𝐞𝐫 🧬
DNATCO v5.0 is a browser-based platform for 3D nucleic acid structure annotation + validation - fast, interactive, privacy-friendly.
📄 doi.org/10.1093/nar/...
🌐 dnatco.datmos.org
January 9, 2026 at 10:05 AM
Congratulations to Prof. Mikael Kubista, recognized as a 2025 ScholarGPS Highly Ranked Scholar™ (Lifetime) — placing him in the top 0.05% of scholars worldwide.
#30 in PCR and #41 in Gene expression profiling.
January 6, 2026 at 11:38 AM
Happy New Year 2026 from IBT CAS ✨
Thanks to everyone we collaborate with — wishing you health, inspiration and exciting discoveries in 2026 🔬🤝
December 31, 2025 at 10:22 AM
Reposted by Institute of Biotechnology
📣We’re proud to announce the successful completion of our first Single-Cell RNA-seq course at the Institute of Molecular Genetics
📅 1–3 December 2025
🤝 In collaboration with ELIXIR CZ, @ibtcas.bsky.social and MetaCentrum
December 16, 2025 at 4:46 PM
𝐆𝐫𝐞𝐚𝐭 𝐭𝐨 𝐬𝐞𝐞 𝐭𝐡𝐞 𝐉𝐮𝐧𝐢𝐨𝐫 𝐅𝐚𝐜𝐮𝐥𝐭𝐲 𝐢𝐧𝐢𝐭𝐢𝐚𝐭𝐢𝐯𝐞 𝐚𝐭 𝐂𝐡𝐚𝐫𝐥𝐞𝐬 𝐔𝐧𝐢𝐯𝐞𝐫𝐬𝐢𝐭𝐲 𝐟𝐞𝐚𝐭𝐮𝐫𝐞𝐝 𝐢𝐧 𝐍𝐚𝐭𝐮𝐫𝐞
👉 1url.cz/eJc6z
Proud that our colleague @katerinarohlena.bsky.social contributed to early discussions and ideas around the #PIForum, which helped inspire initiatives that are now gaining international attention. 🚀
December 15, 2025 at 1:56 PM
🔬 Our new study shows that mitochondrial respiration is essential for early tumour growth. Cancer cells can import mitochondria from nearby cells to restore pyrimidine synthesis and proliferate.
A key vulnerability: DHODH — its loss fully blocks tumour growth.
📄 Cancer Research | 1url.cz/wJOxT
November 28, 2025 at 1:25 PM
Naše kolegyně Aditi Chatterjee získala Pamětní grant Martiny Roeselové 2026! 🎉
Velká gratulace a díky @nf-iocbtech.bsky.social za podporu mladých vědců-rodičů. ❤️
November 27, 2025 at 1:42 PM
🔬 𝐗𝐗𝐕𝐈𝐈𝐈. 𝐁𝐢𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥 𝐃𝐚𝐲𝐬 opened with excellent talks and lively discussions.
Congratulations to Prof. Jaroslav Petr on the Babák Medal.
👉 Join us again tomorrow. 1url.cz/gJOWh
November 25, 2025 at 4:26 PM
Reposted by Institute of Biotechnology
Kateřina Rohlenová @katerinarohlena.bsky.social z @ibtcas.bsky.social je uznávanou vědkyní v oblasti nádorové biologie. V roce 2023 získala podporu grantu MIT-Czech Republic IOCB Tech Foundation Seed Fund, díky němuž navázala spolupráci s MIT a nyní dokončuje přelomový článek o nádorových buňkách. ⤵️
November 24, 2025 at 5:17 PM
🧬 The 4th Prague Symposium on Cancer Metabolism brought together experts to discuss new insights in tumor metabolism.

We’re proud that two of our PhD students — 🏆 Pavel Jakoubě and 🏆 Mariia Hrysiuk — received a Best Poster Prize (2 of only 3 awarded).

👏 Congratulations!
November 14, 2025 at 2:34 PM
Reposted by Institute of Biotechnology
November 13, 2025 at 1:57 PM
💚 𝐓𝐰𝐨 𝐝𝐚𝐲𝐬 𝐟𝐮𝐥𝐥 𝐨𝐟 𝐜𝐮𝐫𝐢𝐨𝐬𝐢𝐭𝐲, 𝐬𝐜𝐢𝐞𝐧𝐜𝐞 𝐚𝐧𝐝 𝐠𝐫𝐞𝐚𝐭 𝐞𝐧𝐞𝐫𝐠𝐲!
Almost 200 students explored our labs 🔬
Maybe some of them will be future scientists — or Nobel Prize winners. 😉
November 11, 2025 at 12:02 PM
🏆 𝗧𝘄𝗼 𝗼𝗳 𝗼𝘂𝗿 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝘀𝘁𝘀 𝗵𝗮𝘃𝗲 𝗯𝗲𝗲𝗻 𝗮𝘄𝗮𝗿𝗱𝗲𝗱 𝗯𝘆 𝘁𝗵𝗲 @akademievedcr.bsky.social
🔬 Prof. Jiří Neužil – 𝗣𝗿𝗮𝗲𝗺𝗶𝘂𝗺 𝗔𝗰𝗮𝗱𝗲𝗺𝗶𝗮𝗲 𝟮𝟬𝟮𝟱
🧫 Dr. Aniruddha Mitra – 𝗟𝘂𝗺𝗶𝗻𝗮 𝗤𝘂𝗮𝗲𝗿𝘂𝗻𝘁𝘂𝗿 𝟮𝟬𝟮𝟱
💚 Congratulations on this exceptional success and recognition of their work!
Read more 👉https://1url.cz/NJIjr
October 30, 2025 at 8:10 AM
RNA is still waiting for its “AlphaFold moment.” 🔬✨
At IBT CAS we’re tackling this challenge head-on.
Read more 👉 1url.cz/YJhsw
October 6, 2025 at 2:09 PM
Don’t miss the opportunity!
Protein Production Hands-On Workshop Dates: December 2 – 4, 2025 Venue: BIOCEV, Vestec Registration Deadline: October 31, 2025 Cost: Free of charge (accommodation not included) Registration Link: forms.biocev.org/index.php/14... Workshop Page: www.ibt.cas.cz/en/core-faci...
October 2, 2025 at 8:04 AM
🆕𝐍𝐞𝐰 𝐫𝐞𝐯𝐢𝐞𝐰 𝐟𝐫𝐨𝐦 𝐨𝐮𝐫 𝐋𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐨𝐟 𝐋𝐢𝐠𝐚𝐧𝐝 𝐄𝐧𝐠𝐢𝐧𝐞𝐞𝐫𝐢𝐧𝐠!
Colleagues explored key drivers of metastatic non-small cell lung cancer (mNSCLC):
🔹 tumor heterogeneity
🔹 oncogenic drivers & resistance
🔹 immunosuppressive TME
📖 biosignaling.biomedcentral.com/articles/10....
October 2, 2025 at 8:02 AM
🚨 New paper out!
We built fiSPR, a platform combining SPR biosensing + light 💡 to study light-responsive proteins.

🔹 Blue light → EL222 dimerization + DNA binding
🔹 UV light → interleukin–receptor interactions

📖 doi.org/10.1016/j.bi...
October 1, 2025 at 12:27 PM
🎉Congratulations to our colleague Daniel Žucha on receiving the 𝙔𝙤𝙪𝙣𝙜 𝙉𝙚𝙪𝙧𝙤𝙨𝙘𝙞𝙚𝙣𝙩𝙞𝙨𝙩𝙨 𝘼𝙬𝙖𝙧𝙙 𝙛𝙤𝙧 𝙊𝙪𝙩𝙨𝙩𝙖𝙣𝙙𝙞𝙣𝙜 𝙒𝙤𝙧𝙠 (𝟮𝟬𝟮𝟯–𝟮𝟬𝟮𝟰) 🧠✨
The prize was awarded by the Czech Neuroscience Society at the biannual #CNS2025 meeting for his work published in PNAS
👉pnas.org/doi/10.1073/pn…
👏
September 22, 2025 at 12:22 PM
At @eisg2025 in Malmö 🇸🇪:
🎤Valeria Fabríciová gave a talk on sex differences in ISL1-deficient diabetic mouse model
📸Věra Slaninová presented her poster on ISL1 and epigenetic regulation in pancreatic endocrine development
Great discussions, and inspiration for future research. Proud of our team! 💡
September 8, 2025 at 1:12 PM