Institute of Biotechnology
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ibtcas.bsky.social
Institute of Biotechnology
@ibtcas.bsky.social
Insight into structural, protein and cellular biology leads to new therapies.

www.ibt.cas.cz
🧬 The 4th Prague Symposium on Cancer Metabolism brought together experts to discuss new insights in tumor metabolism.

We’re proud that two of our PhD students — 🏆 Pavel Jakoubě and 🏆 Mariia Hrysiuk — received a Best Poster Prize (2 of only 3 awarded).

👏 Congratulations!
November 14, 2025 at 2:34 PM
💚 𝐓𝐰𝐨 𝐝𝐚𝐲𝐬 𝐟𝐮𝐥𝐥 𝐨𝐟 𝐜𝐮𝐫𝐢𝐨𝐬𝐢𝐭𝐲, 𝐬𝐜𝐢𝐞𝐧𝐜𝐞 𝐚𝐧𝐝 𝐠𝐫𝐞𝐚𝐭 𝐞𝐧𝐞𝐫𝐠𝐲!
Almost 200 students explored our labs 🔬
Maybe some of them will be future scientists — or Nobel Prize winners. 😉
November 11, 2025 at 12:02 PM
🏆 𝗧𝘄𝗼 𝗼𝗳 𝗼𝘂𝗿 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝘀𝘁𝘀 𝗵𝗮𝘃𝗲 𝗯𝗲𝗲𝗻 𝗮𝘄𝗮𝗿𝗱𝗲𝗱 𝗯𝘆 𝘁𝗵𝗲 @akademievedcr.bsky.social
🔬 Prof. Jiří Neužil – 𝗣𝗿𝗮𝗲𝗺𝗶𝘂𝗺 𝗔𝗰𝗮𝗱𝗲𝗺𝗶𝗮𝗲 𝟮𝟬𝟮𝟱
🧫 Dr. Aniruddha Mitra – 𝗟𝘂𝗺𝗶𝗻𝗮 𝗤𝘂𝗮𝗲𝗿𝘂𝗻𝘁𝘂𝗿 𝟮𝟬𝟮𝟱
💚 Congratulations on this exceptional success and recognition of their work!
Read more 👉https://1url.cz/NJIjr
October 30, 2025 at 8:10 AM
RNA is still waiting for its “AlphaFold moment.” 🔬✨
At IBT CAS we’re tackling this challenge head-on.
Read more 👉 1url.cz/YJhsw
October 6, 2025 at 2:09 PM
🆕𝐍𝐞𝐰 𝐫𝐞𝐯𝐢𝐞𝐰 𝐟𝐫𝐨𝐦 𝐨𝐮𝐫 𝐋𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐨𝐟 𝐋𝐢𝐠𝐚𝐧𝐝 𝐄𝐧𝐠𝐢𝐧𝐞𝐞𝐫𝐢𝐧𝐠!
Colleagues explored key drivers of metastatic non-small cell lung cancer (mNSCLC):
🔹 tumor heterogeneity
🔹 oncogenic drivers & resistance
🔹 immunosuppressive TME
📖 biosignaling.biomedcentral.com/articles/10....
October 2, 2025 at 8:02 AM
🚨 New paper out!
We built fiSPR, a platform combining SPR biosensing + light 💡 to study light-responsive proteins.

🔹 Blue light → EL222 dimerization + DNA binding
🔹 UV light → interleukin–receptor interactions

📖 doi.org/10.1016/j.bi...
October 1, 2025 at 12:27 PM
🎉Congratulations to our colleague Daniel Žucha on receiving the 𝙔𝙤𝙪𝙣𝙜 𝙉𝙚𝙪𝙧𝙤𝙨𝙘𝙞𝙚𝙣𝙩𝙞𝙨𝙩𝙨 𝘼𝙬𝙖𝙧𝙙 𝙛𝙤𝙧 𝙊𝙪𝙩𝙨𝙩𝙖𝙣𝙙𝙞𝙣𝙜 𝙒𝙤𝙧𝙠 (𝟮𝟬𝟮𝟯–𝟮𝟬𝟮𝟰) 🧠✨
The prize was awarded by the Czech Neuroscience Society at the biannual #CNS2025 meeting for his work published in PNAS
👉pnas.org/doi/10.1073/pn…
👏
September 22, 2025 at 12:22 PM
At @eisg2025 in Malmö 🇸🇪:
🎤Valeria Fabríciová gave a talk on sex differences in ISL1-deficient diabetic mouse model
📸Věra Slaninová presented her poster on ISL1 and epigenetic regulation in pancreatic endocrine development
Great discussions, and inspiration for future research. Proud of our team! 💡
September 8, 2025 at 1:12 PM
𝙋𝙤𝙡𝙞𝙨𝙝 🇵🇱 𝙖𝙣𝙙 𝘾𝙯𝙚𝙘𝙝 🇨🇿 𝙍𝙚𝙨𝙚𝙖𝙧𝙘𝙝 𝙏𝙚𝙖𝙢𝙨 𝙈𝙚𝙚𝙩 𝙞𝙣 𝙋𝙤𝙯𝙣𝙖𝙣
📅From Aug 25–29, IBT CAS (Prof. Bohdan Schneider) met with IBCH PAS (Prof. Marta Szachniuk) in Poznań.
🔬 Joint project: AI & graph-based tools for RNA 3D models
🌍 Goal: open-access solutions for computational structural biology.
August 28, 2025 at 1:53 PM
🧠Don’t miss two outstanding neuroscience lectures!
📅Sept 5, 2025
13:00 Prof. Marcela Pekna – “𝙄𝙢𝙥𝙧𝙤𝙫𝙞𝙣𝙜 𝙨𝙩𝙧𝙤𝙠𝙚 𝙧𝙚𝙘𝙤𝙫𝙚𝙧𝙮 – 𝙛𝙧𝙤𝙢 𝙩𝙧𝙖𝙣𝙨𝙘𝙧𝙞𝙥𝙩𝙤𝙢𝙞𝙘𝙨 𝙩𝙤 𝙣𝙚𝙬 𝙩𝙧𝙚𝙖𝙩𝙢𝙚𝙣𝙩 𝙨𝙩𝙧𝙖𝙩𝙚𝙜𝙞𝙚𝙨”
14:00 Prof. Milos Pekny – “𝘼𝙨𝙩𝙧𝙤𝙘𝙮𝙩𝙚𝙨 𝙖𝙨 𝙢𝙖𝙟𝙤𝙧 𝙥𝙡𝙖𝙮𝙚𝙧𝙨 𝙞𝙣 𝘾𝙉𝙎 𝙙𝙞𝙨𝙚𝙖𝙨𝙚𝙨”
📍 IBT, BIOCEV campus, Vestec
August 28, 2025 at 10:44 AM
🚀Věda, která mění životy!
Naše kolegyně Kateřina Komrsková patří mezi světovou špičku v oblasti reprodukční biologie. 🔬✨
V rozhovoru mluví nejen o mužské neplodnosti, ale i o objevech, které mohou pomoci zachránit ohrožené druhy. 🌍💚
👉https://1url.cz/dJVGl
August 27, 2025 at 7:42 AM
🔬 Teach Me in 10: Future of Molecular Diagnostics is coming up!
Join this free event on NGS 🧬, liquid biopsy 💧 & AI diagnostics 🤖.
🎤 Proud that Mikael Kubista from our Institute will be speaking!
👉 1url.cz/yJaXV
August 15, 2025 at 11:43 AM
🚀New publication alert!
In #OpenScience, raw data matters. Meet the Molecular Biophysics Database (MBDB) – a new platform to share and reuse raw data from key biophysical methods, built on FAIR principles.
📄https://link.springer.com/article/10.1007/s00249-025-01789-1
August 11, 2025 at 8:33 AM
Two new top scientists join the International Advisory Board of IBT CAS: Prof. Emanuela Tolosano (Turin) & Prof. Carsten Janke (Orsay/Paris). 🌍
Their expertise in heme metabolism and cytoskeleton biology will support IBT’s strategic growth. 🔬
More: www.ibt.cas.cz/en/news/Inte...
July 28, 2025 at 11:32 AM
New biotech startup Carta Genum, founded by our colleagues Lukas Valihrach & Daniel Žucha, was introduced at #Science4Business.

Born at IBT, supported by SIC, and now ready for the market. Good luck on the journey ahead! 👏
#biotech #spatialbiology #startups
June 30, 2025 at 1:06 PM
🧬 New study: High-affinity Myomedin binders (MLE variants) for PD-L1 detection in NSCLC.
Validated in FFPE tissues, some outperform 28-8 & 22C3 diagnostic antibodies.
Work by @ibtcas + partners
🔗 translational-medicine.biomedcentral.com/articles/10....
June 16, 2025 at 1:02 PM
🏅𝗧𝗵𝗲 𝗜𝗻𝘀𝘁𝗶𝘁𝘂𝘁𝗲 𝗼𝗳 𝗕𝗶𝗼𝘁𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆 𝗵𝗮𝘀 𝗿𝗲𝗰𝗲𝗶𝘃𝗲𝗱 𝘁𝗵𝗲 𝗽𝗿𝗲𝘀𝘁𝗶𝗴𝗶𝗼𝘂𝘀 𝗛𝗥 𝗘𝘅𝗰𝗲𝗹𝗹𝗲𝗻𝗰𝗲 𝗶𝗻 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗔𝘄𝗮𝗿𝗱🔹
This recognition is not just a formal milestone for us—it is a commitment to building an open, motivating, and transparent research organization.
@akademievedcr.bsky.social
June 14, 2025 at 2:19 PM
ʟᴇᴄᴛᴜʀᴇꜱ, ꜱᴜɴ ᴀɴᴅ ꜱᴄɪᴇɴᴄᴇ ɪɴ ʟᴜʜᴀčᴏᴠɪᴄᴇ 🎤🧬
Alice a Pavel took the stage at the 1st CS Congress of Medical Genetics in Luhačovice - thanks to everyone who joined!
#GeneCore #genetics #Luhačovice #science
April 9, 2025 at 1:49 PM