Hans schoofs
@hansschoofs.bsky.social
Post-doc at NKI-AVL - van Rheenen group - Two photon enthusiast- Vascular biologist-
Pinned
Hans schoofs
@hansschoofs.bsky.social
· Mar 20
This work would not have been possible without our many collaborators who provided reagents, lines and much needed support! @ruibenedito.bsky.social, M. Jeansson, @brittae.bsky.social, D. Vestweber, K. Gängel, O. Friedrich, J. van Buul, P. Saharinen, R. Smith and M. Majda and many others!
This beautiful work from the lab in Uppsala @taijamakinenlab.bs made it to the cover ! Happy to be part of it ! Congrats again to the first author Marle Kraft ! Stunning images
❤️Our July issue is out❤️Discover an Angiopoietin-TIE2-dependent circuit promoting venous malformations, complex disease modelling in cardiac organoids, regulation of cardiac homeostasis by methyonil tRNA synthetase, and more!
www.nature.com/natcardiovas...
www.nature.com/natcardiovas...
July 15, 2025 at 5:54 PM
This beautiful work from the lab in Uppsala @taijamakinenlab.bs made it to the cover ! Happy to be part of it ! Congrats again to the first author Marle Kraft ! Stunning images
Extremely grateful to be granted a two year post-doctoral fellowship by @embo.org to study the earliest phases of mutant to malignant cell transition during breast cancer initiation using intravital microscopy. Thank to @vanrheenenlab.bsky.social for the immense support! @nkinl.bsky.social
June 7, 2025 at 10:02 AM
Extremely grateful to be granted a two year post-doctoral fellowship by @embo.org to study the earliest phases of mutant to malignant cell transition during breast cancer initiation using intravital microscopy. Thank to @vanrheenenlab.bsky.social for the immense support! @nkinl.bsky.social
Reposted by Hans schoofs
An imbalance of Angiopoietin ligands & endothelial TIE2 hyperactivation underlies PI3KCA-driven #VenousMalformation👹
⏫ #MuralCell Angpt1
⏬ #EndothelialCell Angpt2
#SciArt
@hansschoofs.bsky.social @taijamakinenlab.bsky.social
@natcardiovascres.nature.com 2025
www.nature.com/articles/s44...
⏫ #MuralCell Angpt1
⏬ #EndothelialCell Angpt2
#SciArt
@hansschoofs.bsky.social @taijamakinenlab.bsky.social
@natcardiovascres.nature.com 2025
www.nature.com/articles/s44...
May 30, 2025 at 11:39 AM
An imbalance of Angiopoietin ligands & endothelial TIE2 hyperactivation underlies PI3KCA-driven #VenousMalformation👹
⏫ #MuralCell Angpt1
⏬ #EndothelialCell Angpt2
#SciArt
@hansschoofs.bsky.social @taijamakinenlab.bsky.social
@natcardiovascres.nature.com 2025
www.nature.com/articles/s44...
⏫ #MuralCell Angpt1
⏬ #EndothelialCell Angpt2
#SciArt
@hansschoofs.bsky.social @taijamakinenlab.bsky.social
@natcardiovascres.nature.com 2025
www.nature.com/articles/s44...
Reposted by Hans schoofs
Angiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformations. Read our work in @natcardiovascres.nature.com by Marle Kraft et al.
rdcu.be/enhST
rdcu.be/enhST
Angiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformations
Nature Cardiovascular Research - Kraft et al. identify TIE2 activation as a key driver of PIK3CA-related venous malformations and demonstrate that inhibiting TIE2 signaling can suppress the growth...
rdcu.be
May 25, 2025 at 2:34 PM
Angiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformations. Read our work in @natcardiovascres.nature.com by Marle Kraft et al.
rdcu.be/enhST
rdcu.be/enhST
Reposted by Hans schoofs
📣New Preview out today @cp-devcell.bsky.social
by Maria Azkanaz & Dimitrios Laskaris, describing the paper by Banjac et al @kimbakjensen.bsky.social lab!
Stemness in flux: Dissecting intestinal crypt organization with multimodal approaches. Check it out here 👇
authors.elsevier.com/c/1l2MG5Sx5g...
by Maria Azkanaz & Dimitrios Laskaris, describing the paper by Banjac et al @kimbakjensen.bsky.social lab!
Stemness in flux: Dissecting intestinal crypt organization with multimodal approaches. Check it out here 👇
authors.elsevier.com/c/1l2MG5Sx5g...
May 5, 2025 at 3:18 PM
📣New Preview out today @cp-devcell.bsky.social
by Maria Azkanaz & Dimitrios Laskaris, describing the paper by Banjac et al @kimbakjensen.bsky.social lab!
Stemness in flux: Dissecting intestinal crypt organization with multimodal approaches. Check it out here 👇
authors.elsevier.com/c/1l2MG5Sx5g...
by Maria Azkanaz & Dimitrios Laskaris, describing the paper by Banjac et al @kimbakjensen.bsky.social lab!
Stemness in flux: Dissecting intestinal crypt organization with multimodal approaches. Check it out here 👇
authors.elsevier.com/c/1l2MG5Sx5g...
• Happy to announce that our paper in @nature.com is finally out! Thanks to the perseverance of @taijamakinenlab.bsky.social and our many collaborators we finally pulled it off! A small 🧵
www.nature.com/articles/s41...
Laymen video:
www.nature.com/articles/d41...
www.nature.com/articles/s41...
Laymen video:
www.nature.com/articles/d41...
Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium - Nature
Dynamic cytoskeletal regulation of lymphatic endothelial cell shape, induced by isotropic stretch and crucial for dermal lymphatic capillary function, is identified and found to result from continuous...
www.nature.com
March 20, 2025 at 2:05 PM
• Happy to announce that our paper in @nature.com is finally out! Thanks to the perseverance of @taijamakinenlab.bsky.social and our many collaborators we finally pulled it off! A small 🧵
www.nature.com/articles/s41...
Laymen video:
www.nature.com/articles/d41...
www.nature.com/articles/s41...
Laymen video:
www.nature.com/articles/d41...
After 5 years my scientific chapter in Uppsala is coming to an end. Two weeks ago I have successfully defended my PhD thesis at the Mäkinenlab. Big thanks to Taija for being a true mentor and to Holger Gerhardt for acting as my opponent and critically assessing my work.
January 6, 2025 at 12:40 PM
After 5 years my scientific chapter in Uppsala is coming to an end. Two weeks ago I have successfully defended my PhD thesis at the Mäkinenlab. Big thanks to Taija for being a true mentor and to Holger Gerhardt for acting as my opponent and critically assessing my work.