Alexander Haglund
haglunda.bsky.social
Alexander Haglund
@haglunda.bsky.social
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Very excited to share our latest publication in @NatureGenet! Our manuscript shows how Mendelian Randomization (MR) isolates putatively causal links between cell-type specific gene expression & brain phenotypes.
www.nature.com/articles/s41...

Tweetorial below 👇
Reposted by Alexander Haglund
We're so thrilled to finally share with you the published version of our CUT&Tag optimization and benchmarking paper "CUT&Tag recovers up to half of ENCODE ChIP-seq histone acetylation peaks" - out in @naturecomms.bsky.social today: www.nature.com/articles/s41...
CUT&Tag recovers up to half of ENCODE ChIP-seq histone acetylation peaks - Nature Communications
Cleavage Under Targets & Tagmentation is a rapidly expanding technique, but thorough evaluation and benchmarking against established ChIP-seq datasets are required. This study shows that CUT&T...
www.nature.com
March 27, 2025 at 11:16 AM
Reposted by Alexander Haglund
A study in Nature Medicine provides a comprehensive map of the contributions of environment and genetics to mortality and incidence of common age-related diseases, suggesting that the exposome shapes distinct patterns of disease and mortality risk. #Medsky 🧪
Integrating the environmental and genetic architectures of aging and mortality - Nature Medicine
Based on a systematic analysis of environmental exposures associated with aging and mortality in the UK Biobank, the relative contributions of such exposures and genetic risk for mortality and a range of age-related diseases were compared, highlighting the potential beneficial effects of environment-focused interventions.
go.nature.com
March 1, 2025 at 2:34 AM
Very excited to share our latest publication in @NatureGenet! Our manuscript shows how Mendelian Randomization (MR) isolates putatively causal links between cell-type specific gene expression & brain phenotypes.
www.nature.com/articles/s41...

Tweetorial below 👇
January 14, 2025 at 8:22 AM