Leo Yuan
@greatysp.bsky.social
Senior Scientist @Altos Labs | Formerly Stem Cell / Cancer Bio at @thefuchslab.bsky.social @rockefelleruniv.bsky.social @hhmi.bsky.social
& Pulmonary Bio at @ucsfmedicine.bsky.social | Co-founder @Aer Therapeutics | Theatre & Art Lover | Adventurer
& Pulmonary Bio at @ucsfmedicine.bsky.social | Co-founder @Aer Therapeutics | Theatre & Art Lover | Adventurer
Reposted by Leo Yuan
New paper alert! We report in @cp-cellmetabolism.bsky.social how serine regulates stem cell fate in physiology and upon wounding.
Good work, Jesse and collabs!
www.cell.com/cell-metabol...
Good work, Jesse and collabs!
www.cell.com/cell-metabol...
The integrated stress response fine-tunes stem cell fate decisions upon serine deprivation and tissue injury
Novak et al. discover that dietary serine impacts whether hair follicle stem cells
(HFSCs) prioritize hair growth or skin repair after injury. HFSCs gauge metabolic
stress using the ISR and accelerate...
www.cell.com
June 12, 2025 at 3:38 PM
New paper alert! We report in @cp-cellmetabolism.bsky.social how serine regulates stem cell fate in physiology and upon wounding.
Good work, Jesse and collabs!
www.cell.com/cell-metabol...
Good work, Jesse and collabs!
www.cell.com/cell-metabol...
Fantastic talk by @thefuchslab.bsky.social on the highly anticipated work on inflammatory memory with aging… congratulations to @chris-cowley14.bsky.social @rajsajjath.bsky.social et al
May 29, 2025 at 6:11 PM
Fantastic talk by @thefuchslab.bsky.social on the highly anticipated work on inflammatory memory with aging… congratulations to @chris-cowley14.bsky.social @rajsajjath.bsky.social et al
Congratulations to @jorgealmagro.bsky.social and @thefuchslab.bsky.social as well!! 🎊🎉🥳🥳 @rockefelleruniv.bsky.social @hhmi.bsky.social
🥳 Our 4th most downloaded article in 2024:
Beyond genetics: driving cancer with the tumour microenvironment behind the wheel by @thefuchslab.bsky.social & colleagues
https://bit.ly/42Cvr...
@rockefelleruniv.bsky.social @hhmi.bsky.social @natureportfolio.bsky.social #NRCtop10of2024
Beyond genetics: driving cancer with the tumour microenvironment behind the wheel by @thefuchslab.bsky.social & colleagues
https://bit.ly/42Cvr...
@rockefelleruniv.bsky.social @hhmi.bsky.social @natureportfolio.bsky.social #NRCtop10of2024
Beyond genetics: driving cancer with the tumour microenvironment behind the wheel - Nature Reviews Cancer
In their Review article, Fuchs and colleagues discuss how a single or a few mutations in adult cells can lead to invasive cancers without a high mutational burden, demonstrating that non-genetic factors induce the epigenetic changes necessary for tumorigenesis.
bit.ly
February 11, 2025 at 2:27 PM
Congratulations to @jorgealmagro.bsky.social and @thefuchslab.bsky.social as well!! 🎊🎉🥳🥳 @rockefelleruniv.bsky.social @hhmi.bsky.social
Reposted by Leo Yuan
Our first 2025 paper!
We discuss in @natrevmcb.bsky.social how epithelial stem cells mechanically sculpt tissues, and how these forces are altered in cancer.
Great work from our former and current tumor mechanobiology experts Vince Fiore & @jorgealmagro.bsky.social 👏
www.nature.com/articles/s41...
We discuss in @natrevmcb.bsky.social how epithelial stem cells mechanically sculpt tissues, and how these forces are altered in cancer.
Great work from our former and current tumor mechanobiology experts Vince Fiore & @jorgealmagro.bsky.social 👏
www.nature.com/articles/s41...
Shaping epithelial tissues by stem cell mechanics in development and cancer - Nature Reviews Molecular Cell Biology
Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of mechanical forces produced by epithelial stem cell a...
www.nature.com
January 29, 2025 at 5:00 PM
Our first 2025 paper!
We discuss in @natrevmcb.bsky.social how epithelial stem cells mechanically sculpt tissues, and how these forces are altered in cancer.
Great work from our former and current tumor mechanobiology experts Vince Fiore & @jorgealmagro.bsky.social 👏
www.nature.com/articles/s41...
We discuss in @natrevmcb.bsky.social how epithelial stem cells mechanically sculpt tissues, and how these forces are altered in cancer.
Great work from our former and current tumor mechanobiology experts Vince Fiore & @jorgealmagro.bsky.social 👏
www.nature.com/articles/s41...
Reposted by Leo Yuan
Congratulations to @jorgealmagro.bsky.social @thefuchslab.bsky.social @rockefelleruniv.bsky.social @hhmi.bsky.social for this landmark review! And happy snake year! 🐍🧧
Very happy to see our review out in @natrevmcb.bsky.social!
Here we discuss how stem cells exert forces to sculpt tissues in development and homeostasis, and how stem cell mechanics go awry upon malignant transformation. Read it here 👇
www.nature.com/articles/s41...
Here we discuss how stem cells exert forces to sculpt tissues in development and homeostasis, and how stem cell mechanics go awry upon malignant transformation. Read it here 👇
www.nature.com/articles/s41...
Shaping epithelial tissues by stem cell mechanics in development and cancer - Nature Reviews Molecular Cell Biology
Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of mechanical forces produced by epithelial stem cell a...
www.nature.com
January 29, 2025 at 6:45 PM
Congratulations to @jorgealmagro.bsky.social @thefuchslab.bsky.social @rockefelleruniv.bsky.social @hhmi.bsky.social for this landmark review! And happy snake year! 🐍🧧
Reposted by Leo Yuan
Kicking off 2025 Paper of the Week with @kevinng.bsky.social & @fesubtil.bsky.social. Today we discussed our friend @martinaparigi.bsky.social et al. recent paper in @nature.com. How do epithelia unlink necessary drivers of regeneration from malignant transformation?
www.nature.com/articles/s41...
www.nature.com/articles/s41...
January 9, 2025 at 8:37 PM
Kicking off 2025 Paper of the Week with @kevinng.bsky.social & @fesubtil.bsky.social. Today we discussed our friend @martinaparigi.bsky.social et al. recent paper in @nature.com. How do epithelia unlink necessary drivers of regeneration from malignant transformation?
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Leo Yuan
Proud to be part of the journey! @thefuchslab.bsky.social @jorgealmagro.bsky.social @rockefelleruniv.bsky.social
2024 was a year of exciting discoveries and scientific discussions! A thread 🪡 of this years’ publications from our lab 👇🏼
January 2, 2025 at 4:47 PM
Proud to be part of the journey! @thefuchslab.bsky.social @jorgealmagro.bsky.social @rockefelleruniv.bsky.social