Genomes & Genetics
@gengenip.bsky.social
Exploring the genomes of bacteria, yeast, and humans @InstitutPasteur to shed new lights on their genetics, function, and evolution.
https://research.pasteur.fr/fr/department/genomes-genetics/
https://research.pasteur.fr/fr/department/genomes-genetics/
Reposted by Genomes & Genetics
And for those interested, there is a computational tool to find them made by @jmouradesousa.bsky.social satelliteFinder doi.org/10.1093/nar/... available at galaxy.pasteur.fr/root?tool_id.... Look out for v2!
Identification and characterization of thousands of bacteriophage satellites across bacteria
Abstract. Bacteriophage–bacteria interactions are affected by phage satellites, elements that exploit phages for transfer between bacteria. Satellites can
doi.org
March 27, 2025 at 6:45 PM
And for those interested, there is a computational tool to find them made by @jmouradesousa.bsky.social satelliteFinder doi.org/10.1093/nar/... available at galaxy.pasteur.fr/root?tool_id.... Look out for v2!
Reposted by Genomes & Genetics
Phage satellites are now known to be very diverse, numerous and ancient. They pose many evolutionary, ecological and mechanistic questions. Lots of fun in perspective!
Great pleasure to write this review to show it, with @jrpenades.bsky.social @dbikard.bsky.social Kim Seed & John Chen.
Great pleasure to write this review to show it, with @jrpenades.bsky.social @dbikard.bsky.social Kim Seed & John Chen.
New online! Genetics, ecology and evolution of phage satellites
Genetics, ecology and evolution of phage satellites
Nature Reviews Microbiology, Published online: 27 March 2025; doi:10.1038/s41579-025-01156-zIn this Review, Penadés et al. explore the genetics, potential origins and life cycle of phage satellites, and they discuss the impact of these elements on the evolution of other mobile genetic elements and their host bacteria.
www.nature.com
March 27, 2025 at 6:45 PM
Phage satellites are now known to be very diverse, numerous and ancient. They pose many evolutionary, ecological and mechanistic questions. Lots of fun in perspective!
Great pleasure to write this review to show it, with @jrpenades.bsky.social @dbikard.bsky.social Kim Seed & John Chen.
Great pleasure to write this review to show it, with @jrpenades.bsky.social @dbikard.bsky.social Kim Seed & John Chen.
Reposted by Genomes & Genetics
Two more weeks to apply to join us in Paris !
research.pasteur.fr/en/call/call...
research.pasteur.fr/en/call/call...
Call for applications 2025 - Creation of new research groups at the Institut Pasteur - Research
The Institut Pasteur launches an international call to recruit new junior research group leaders in the application of cutting-edge transdisciplinary approaches to the exploration of host-microbe, tis...
research.pasteur.fr
February 13, 2025 at 6:09 PM
Two more weeks to apply to join us in Paris !
research.pasteur.fr/en/call/call...
research.pasteur.fr/en/call/call...
Reposted by Genomes & Genetics
Our latest work: how can compartmentalization emerge in a eukaryotic genome lacking canonical heterochromatin?
By investigating bacterial genomes put in yeast, we show that the presence or absence of transcription is sufficient!
#chromatin #3Dgenome #generegulation
www.science.org/doi/10.1126/...
👇
By investigating bacterial genomes put in yeast, we show that the presence or absence of transcription is sufficient!
#chromatin #3Dgenome #generegulation
www.science.org/doi/10.1126/...
👇
Sequence-dependent activity and compartmentalization of foreign DNA in a eukaryotic nucleus
In eukaryotes, DNA-associated protein complexes coevolve with genomic sequences to orchestrate chromatin folding. We investigate the relationship between DNA sequence and the spontaneous loading and a...
www.science.org
February 7, 2025 at 10:22 AM
Our latest work: how can compartmentalization emerge in a eukaryotic genome lacking canonical heterochromatin?
By investigating bacterial genomes put in yeast, we show that the presence or absence of transcription is sufficient!
#chromatin #3Dgenome #generegulation
www.science.org/doi/10.1126/...
👇
By investigating bacterial genomes put in yeast, we show that the presence or absence of transcription is sufficient!
#chromatin #3Dgenome #generegulation
www.science.org/doi/10.1126/...
👇
Reposted by Genomes & Genetics
#RésultatScientifique🔎 Quand un ADN étranger s'intègre dans une cellule hôte, comment s’adapte-t-il aux règles métaboliques de son nouvel occupant ? @rkoszul.bsky.social et ses collaborateurs ont enquêté ! 🕵️
🤝 @cnrs.bsky.social @pasteur.fr @mnhn.fr
https://buff.ly/40GvJL2
🤝 @cnrs.bsky.social @pasteur.fr @mnhn.fr
https://buff.ly/40GvJL2
Prédire l’organisation et l’activité d’un ADN étranger dans une cellule hôte
Les transferts d’ADN d’une espèce à une autre sont des événements fréquents et naturels.
www.insb.cnrs.fr
February 7, 2025 at 10:00 AM
#RésultatScientifique🔎 Quand un ADN étranger s'intègre dans une cellule hôte, comment s’adapte-t-il aux règles métaboliques de son nouvel occupant ? @rkoszul.bsky.social et ses collaborateurs ont enquêté ! 🕵️
🤝 @cnrs.bsky.social @pasteur.fr @mnhn.fr
https://buff.ly/40GvJL2
🤝 @cnrs.bsky.social @pasteur.fr @mnhn.fr
https://buff.ly/40GvJL2
Reposted by Genomes & Genetics
Here's a project with surprising results: we show the presence of virulent phages across bacterial genome assemblies. Not any phage, and not your typical T1 contaminant, many phages have large genomes and seem to be in a state of persistence/oscillation (?!) between lysogeny and the lytic cycle.
Are there virulent phages hiding in your bacterial culture? Here we find hundreds of virulent phage genomes in bacterial genome assemblies. Bioinformatic and experimental evidence indicate these are not contaminations, but represent persistent infections.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Persistent virulent phages exist in bacterial isolates
Despite the immense diversity of tailed bacteriophages, they are traditionally classified as either virulent or temperate, with only the latter thought capable of long-term persistence in bacterial ce...
www.biorxiv.org
January 3, 2025 at 9:56 AM
Here's a project with surprising results: we show the presence of virulent phages across bacterial genome assemblies. Not any phage, and not your typical T1 contaminant, many phages have large genomes and seem to be in a state of persistence/oscillation (?!) between lysogeny and the lytic cycle.
Reposted by Genomes & Genetics
🦠Bacteria serve as an amazing reservoir of immune genes for eukaryotes but also of essential cellular functions!
⬇️New exaptation example : euk RNA-guided RNA modification originated from "bridge RNA" IS110 transposons.
Led by @hugovaysset.bsky.social and C. Meers from Sternberg lab! rdcu.be/d5ovZ
⬇️New exaptation example : euk RNA-guided RNA modification originated from "bridge RNA" IS110 transposons.
Led by @hugovaysset.bsky.social and C. Meers from Sternberg lab! rdcu.be/d5ovZ
Evolutionary origins of archaeal and eukaryotic RNA-guided RNA modification in bacterial IS110 transposons
Nature Microbiology - Structural and phylogenetic analyses show that programmable RNA modifications ubiquitous in archaea and eukarya arose from bacterial transposons.
rdcu.be
January 6, 2025 at 10:24 AM
🦠Bacteria serve as an amazing reservoir of immune genes for eukaryotes but also of essential cellular functions!
⬇️New exaptation example : euk RNA-guided RNA modification originated from "bridge RNA" IS110 transposons.
Led by @hugovaysset.bsky.social and C. Meers from Sternberg lab! rdcu.be/d5ovZ
⬇️New exaptation example : euk RNA-guided RNA modification originated from "bridge RNA" IS110 transposons.
Led by @hugovaysset.bsky.social and C. Meers from Sternberg lab! rdcu.be/d5ovZ
Reposted by Genomes & Genetics
The international Curie « Noncoding Genome » course has been revamped! 👉 Dark genome in cell plasticity and heterogeneity. A session on TEs #TEsky with M.E. Torres Padilla, D.Trono and @aktast.bsky.social. Master, PhD and postdoc fellows, a week in Paris during the Spring?
Apply before Feb 15th
📌
Apply before Feb 15th
📌
November 28, 2024 at 7:21 PM
The international Curie « Noncoding Genome » course has been revamped! 👉 Dark genome in cell plasticity and heterogeneity. A session on TEs #TEsky with M.E. Torres Padilla, D.Trono and @aktast.bsky.social. Master, PhD and postdoc fellows, a week in Paris during the Spring?
Apply before Feb 15th
📌
Apply before Feb 15th
📌
Reposted by Genomes & Genetics
🚨Postdoc position(s) alert🚨 If you like to develop new bioinformatic tools for *human* microbiome analysis, are interested by virus/phages, we (JGI Viral Genomics and Microbiome Data groups) may have a great position for you ! No official job posting yet, but email or DM if you are interested !
January 7, 2025 at 9:12 PM
🚨Postdoc position(s) alert🚨 If you like to develop new bioinformatic tools for *human* microbiome analysis, are interested by virus/phages, we (JGI Viral Genomics and Microbiome Data groups) may have a great position for you ! No official job posting yet, but email or DM if you are interested !
The department of Genomes and Genetics at Institut Pasteur on Bluesky !
Exploring the genomes and communities of bacteria, yeast, and humans to shed new lights on their genetics, function, and evolution.
Exploring the genomes and communities of bacteria, yeast, and humans to shed new lights on their genetics, function, and evolution.
November 14, 2024 at 11:55 AM
The department of Genomes and Genetics at Institut Pasteur on Bluesky !
Exploring the genomes and communities of bacteria, yeast, and humans to shed new lights on their genetics, function, and evolution.
Exploring the genomes and communities of bacteria, yeast, and humans to shed new lights on their genetics, function, and evolution.