Francois Sabot
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francoissabot.bsky.social
Francois Sabot
@francoissabot.bsky.social
Scientist, biologist, #evolution and #pangenomics, #bioinformatics, #AI and #OpenScience @ird_fr - and a little bit a #geek too
mastodon: @francois_sabot@genomic.social
Reposted by Francois Sabot
#IARACU ⛴️
Interviewée par M6 à bord de la caravane fluviale scientifique
Avec @IARACU, nous avons réuni +100 scientifiques de différentes nationalités pour relier science, société & décideurs.
À revoir ici :: www.m6.fr/le-1245-p_10...
Le 1245 - Le 1245 du 11/11/2025 - M6+
Voir votre programme Le 1245 sur M6+
www.m6.fr
November 13, 2025 at 8:37 AM
Reposted by Francois Sabot
Renforcer la confiance dans la science : participez à la conférence internationale organisée par l’ANR et Science Europe | 11 décembre 2025
Renforcer la confiance dans la science : participez à la conférence internationale organisée par l’ANR et Science Europe | 11 décembre 2025
« Le 11 décembre, l’Agence nationale de la recherche (ANR) et Science Europe vous invitent à assister à la conférence internationale « Strengthening Public Trust in Science – Analysing the ch…
lalist.inist.fr
November 12, 2025 at 8:48 AM
Reposted by Francois Sabot
Bioinformatics x cybersecurity: Christina Boucher and her colleague Sara Rampazzi uncovered a basic yet critical vulnerability in MinIONs through the MinKNOW software bioengineer.org/portable-gen...
Portable Genetic Sequencer Security Vulnerabilities Could Endanger Personal
Portable genetic sequencers, particularly those manufactured by Oxford Nanopore Technologies, have revolutionized the field of genomics, making DNA sequencing more accessible and practical across the
bioengineer.org
November 12, 2025 at 7:44 AM
Reposted by Francois Sabot
Les collègues avaient trouvé une super idée pour un prix à une conférence : avoir son travail illustré par quelqu'un dont c'est le métier. Je mets ça là au cas où :D
November 8, 2025 at 11:15 AM
Reposted by Francois Sabot
Voici une image du soleil obtenue en 2014 par la sonde Solar Dynamics Observatory. Et oui, le soleil aussi aime se préparer pour Halloween !
October 31, 2025 at 8:26 AM
Yesterday, Nina Marthe, our wonderful PhD student with Matthias Zytnicky, resubmit our tool GrAnnoT, for pangenome variation graph annotation!

@ird-fr.bsky.social @inrae-france.bsky.social @peercommunityin.bsky.social #pangenomics 💻

www.biorxiv.org/content/10.1...
GrAnnoT, a tool for efficient and reliable annotation transfer through pangenome graph
The increasing availability of genome sequences has highlighted the limitations of using a single reference genome to represent the diversity within a species. Pangenomes, encompassing the genomic inf...
www.biorxiv.org
October 30, 2025 at 3:46 PM
A few days ago, we updated our analysis on the cosmopolitan green algae Bathycoccus prasinos and its genomic resources. My former PhD student, Dr Louis Dennu, performed a huge work to reframe the paper! @ird-fr.bsky.social @cnrs.fr

www.biorxiv.org/content/10.1...
Biological and genomic resources for the cosmopolitan phytoplankton Bathycoccus: Insights into genetic diversity and function of outlier chromosomes
Population-scale genome sequencing has become essential for exploring genetic diversity and adaptation, particularly in land plants. In contrast, eukaryotic phytoplankton resources remain limited to m...
www.biorxiv.org
October 30, 2025 at 3:39 PM
Reposted by Francois Sabot
1/2 Want to become up to date with pangenomes and genome graphs and their history? Check out this fantastic review by @zbao.bsky.social!

Complexity welcome: Pangenome graphs for comprehensive population genomics
#pangenomes #plantscience #genomegraphs
www.cambridge.org/core/journal...
October 27, 2025 at 5:53 PM
Reposted by Francois Sabot
LLMs4All: A Review of Large Language Models Across Academic Disciplines www.preprints.org/frontend/man...
www.preprints.org
October 25, 2025 at 8:17 AM
Reposted by Francois Sabot
🖥️ There is still time to register and join this year's BioHackathon Europe! Learn more about participating ERGA members and the projects they will develop: www.erga-biodiversity.eu/post/erga-at... #BioHackEU25 #biohackathon #bioinformartics #community @elixir-europe.org @biogeneurope.bsky.social
October 21, 2025 at 9:12 AM
Reposted by Francois Sabot
Ca n'est pas si souvent, un article publié dans Nature met ma communauté à l'honneur (la bioinformatique des séquences). Je vous raconte ?
www.nature.com/articles/d41...
‘Google for DNA’ brings order to biology’s big data
MetaGraph compresses vast data archives into a search engine for scientists, opening up new frontiers of biological discovery.
www.nature.com
October 9, 2025 at 3:00 PM
Reposted by Francois Sabot
Hier journée interCoSav 💡
Retour sur la mobilisation des #CoSav lors des grands moments internationaux
Riches échanges sur les perspectives de renforcement, le besoin d’appui, le dialogue sciences-politiques-société, pour nourrir les réflexions sur leur évolution & sur les sciences de la durabilité
October 2, 2025 at 7:56 AM
Reposted by Francois Sabot
✨Très belle expo "Éclaireuses" d' @ird-fr.bsky.social avec #photoclimat #ONUFemmesFrance @agencerecherche.bsky.social @paris.fr
Portraits de femmes scientifiques de l'IRD et de ses partenaires👩‍🔬
L'IRD soutient une recherche inclusive & la formation des citoyen(ne)s de demain
👉12/10/25-Quais de Seine
September 29, 2025 at 10:00 AM
Avec plusieurs collègues du Collègue Logiciels de la recherche du Comité pour la Science Ouverte, nous avons produit un document de stratégie d'établissement pour al diffusion et la pérennité dans l'ESR. On revient sur les #opensoftware #openscience @ird-fr.bsky.social

dx.doi.org/10.52949/82
Quelles stratégies de diffusion et pérennité pour les logiciels de recherche dans les établissements publics français ?
Le présent document propose une analyse de la diffusion et de la pérennité des travaux scientifiques de type logiciel produits par les établissements de recherche français. Partant du constat qu’il n’...
dx.doi.org
September 29, 2025 at 1:04 PM
Reposted by Francois Sabot
Ravie d'avoir rencontré Clarisse Angelier, déléguée générale de l'ANRT: l'occasion d’aborder la collaboration de recherche public-privé, le dispositif CIFRE, son potentiel à l’international et de l'opportunité d'accroitre ce dispositif à l'@ird-fr.bsky.social
September 25, 2025 at 6:34 PM
Reposted by Francois Sabot
Et je pense que pour un paquet d'entre nous, sa version du Faucheur nous aide à apaiser l'idée de la fin, celles des gens qu'on aime comme la nôtre.
💀 Le 9 octobre prochain paraîtra mon livre Terry Pratchett et la Mort : Mourir en majuscules (@edlatalante.bsky.social).
La mort est un sujet central dans l’œuvre et la vie de Pratchett, une évidence qu’il a longtemps cherché à comprendre et non à craindre.
1/4
www.l-atalante.com/catalogue/la...
Terry Pratchett et la Mort : Mourir en majuscules | Éditions L'Atalante
C’EST BIEN DE LEURS COUPS, AUX MORTELS.ILS N’ONT QUE QUELQUES ANNÉES DEVANT EUX,ET ILS LES PASSENT À SE COMPLIQUER LA VIE.FASCINANT. PRENDS...
www.l-atalante.com
September 21, 2025 at 12:03 PM
Reposted by Francois Sabot
Hi! We are looking for a PhD to work on the cross talk between transposable elements, insects and intracellular bacteria on the bioinformatics side. The PhD would be supervised by @mariefablet.bsky.social and myself along with @nicolasparisot.bsky.social Deadline December 2025! Please share! #tesky
September 16, 2025 at 6:13 AM
Reposted by Francois Sabot
Deep genome sequencing reveals extensive genetic heterogeneity in early human placentas. #HumanPlacenta #PlacentaGenetics @natcomms.nature.com 🧬
www.nature.com/articles/s41...
September 14, 2025 at 10:31 AM
Reposted by Francois Sabot
🧬🌱 Excited to share our new preprint. Large effort by Fede, Manuel, Enzo, and other 112 plant biologists. In short, LLMs perform better on well-established knowledge from highly cited sources but struggle with cutting-edge research www.biorxiv.org/content/10.1... #plantscience
What Large Language Models Know About Plant Molecular Biology
Large language models (LLMs) are rapidly permeating scientific research, yet their capabilities in plant molecular biology remain largely uncharacterized. Here, we present MoBiPlant, the first compreh...
www.biorxiv.org
September 9, 2025 at 10:26 AM
Reposted by Francois Sabot
Microsoft Word to begin saving people's documents in the cloud *by default*

Reminder that LibreOffice is free and a good drop-in replacement for Microsoft Office software: www.libreoffice.org

www.theverge.com/news/767522/...
Microsoft Word now automatically saves new documents to the cloud
Word documents will be automatically saved to OneDrive
www.theverge.com
September 3, 2025 at 12:23 PM
Reposted by Francois Sabot
🌎👩‍🔬 For 15+ years biology has accumulated petabytes (million gigabytes) of🧬DNA sequencing data🧬 from the far reaches of our planet.🦠🍄🌵

Logan now democratizes efficient access to the world’s most comprehensive genetics dataset. Free and open.

doi.org/10.1101/2024...
September 3, 2025 at 8:39 AM
Reposted by Francois Sabot
How diverse are the individual strains within your species?
How broad is their Pangenome?
How will you choose representatives from the whole collection?

Look no further! PanGene-O-Meter is here for you!
From @haimashkenazy.bsky.social @plantevolution.bsky.social

www.biorxiv.org/content/10.1...
PanGene-O-Meter: Intra-Species Diversity Based on Gene-Content
Bacterial genome evolution is shaped to a great extent by horizontal gene transfer, detectable as genes with a presence-absence pattern of variation that does not follow phylogenetic relationships acr...
www.biorxiv.org
September 2, 2025 at 7:20 AM
Reposted by Francois Sabot
Reposted by Francois Sabot
Anyone can be the best: Impact of diverse methodologies on the evaluation of structural variant callers www.biorxiv.org/content/10.1... 🧬🖥️🧪 github.com/ldenti/svben...
September 2, 2025 at 9:07 AM
Reposted by Francois Sabot
Thrilled to share our latest work focusing on graph-based pangenome analysis highlighting structural and functional consequences of allopolyploidization

www.biorxiv.org/content/10.1...
Graph-based pangenome analysis uncovers structural and functional impacts of allopolyploidization events
The emergence of graph pangenomes has significantly advanced the study of structural variants (SVs) across diverse species. However, the impact of complex polyploidization events, particularly allopol...
www.biorxiv.org
September 1, 2025 at 8:03 AM