Fraser MacLeod
@fmacleod.bsky.social
Postdoc in the Baum lab at the MRC-LMB, studying the diversity and behaviour of Asgard archaea
Reposted by Fraser MacLeod
And just when you thought things were settling down, the enigmatic Asgard archaea have another surprise in store! Cell cycle/life cycle stage-specific internal compartments with almost no eukaryote-derived clues as to how they might function.
Beautiful tomography and microscopy - congrats all 🤩
Beautiful tomography and microscopy - congrats all 🤩
An Asgard archaeon with internal membrane compartments
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
November 7, 2025 at 10:56 AM
And just when you thought things were settling down, the enigmatic Asgard archaea have another surprise in store! Cell cycle/life cycle stage-specific internal compartments with almost no eukaryote-derived clues as to how they might function.
Beautiful tomography and microscopy - congrats all 🤩
Beautiful tomography and microscopy - congrats all 🤩
Was a wild journey also with @magdalechowska.bsky.social @joeparham19.bsky.social @iainrichard.bsky.social @emaguilarpine.bsky.social @archaeal.bsky.social Heimdallarchaeia are beautiful!
An Asgard archaeon with internal membrane compartments
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
November 7, 2025 at 11:36 AM
Was a wild journey also with @magdalechowska.bsky.social @joeparham19.bsky.social @iainrichard.bsky.social @emaguilarpine.bsky.social @archaeal.bsky.social Heimdallarchaeia are beautiful!
Reposted by Fraser MacLeod
Thrilled to see our work published in @embojournal.org
#asgard #archaea #cytoskeleton #tubulin #FtsZ
We sincerely appreciate the constructive peer review and the reviewers’ thoughtful, supportive feedback, which greatly strengthened our work.
#asgard #archaea #cytoskeleton #tubulin #FtsZ
We sincerely appreciate the constructive peer review and the reviewers’ thoughtful, supportive feedback, which greatly strengthened our work.
Insights into the origins of the #tubulin / #FtsZ superfamily: @syncellbiolab.bsky.social, Pananghat Gayathri et al show that two #Asgard archaeal paralogs OdinFtsZ1 and OdinFtsZ2 form distinct filamental structures, and employ different modes of membrane tethering
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
August 8, 2025 at 11:49 AM
Thrilled to see our work published in @embojournal.org
#asgard #archaea #cytoskeleton #tubulin #FtsZ
We sincerely appreciate the constructive peer review and the reviewers’ thoughtful, supportive feedback, which greatly strengthened our work.
#asgard #archaea #cytoskeleton #tubulin #FtsZ
We sincerely appreciate the constructive peer review and the reviewers’ thoughtful, supportive feedback, which greatly strengthened our work.
Reposted by Fraser MacLeod
Out now in its final peer-reviewed form @asm.org's Journal of Virology!
doi.org/10.1128/jvi....
@dome-vienna.bsky.social @erc.europa.eu @amersocvirology.bsky.social
doi.org/10.1128/jvi....
@dome-vienna.bsky.social @erc.europa.eu @amersocvirology.bsky.social
June 13, 2025 at 9:14 PM
Out now in its final peer-reviewed form @asm.org's Journal of Virology!
doi.org/10.1128/jvi....
@dome-vienna.bsky.social @erc.europa.eu @amersocvirology.bsky.social
doi.org/10.1128/jvi....
@dome-vienna.bsky.social @erc.europa.eu @amersocvirology.bsky.social
Reposted by Fraser MacLeod
We are excited to share our preprint describing how Sulfolobus cells coordinate DNA segregation with cell division! In eukaryotes this type of regulation involves checkpoints and CDK-cyclins. But how does this work in archaea? This is the question we ask in our paper: www.biorxiv.org/content/10.1...
Temporal and spatial coordination of DNA segregation and cell division in an archaeon.
Cells must coordinate DNA segregation with cytokinesis to ensure that each daughter cell inherits a complete genome. Here, we explore how DNA segregation and division are mechanistically coupled in ar...
www.biorxiv.org
May 29, 2025 at 3:36 PM
We are excited to share our preprint describing how Sulfolobus cells coordinate DNA segregation with cell division! In eukaryotes this type of regulation involves checkpoints and CDK-cyclins. But how does this work in archaea? This is the question we ask in our paper: www.biorxiv.org/content/10.1...