⚡️GREG_CORDER⚡️
@flybottleescape.bsky.social
Assistant Professor @ Penn | Dept Psychiatry + Dept Neuroscience + Dept Anesthesiology | Pain • Placebo • Poppies • Psychedelics
https://corderlab.com/
https://corderlab.com/
Check out this amazing recognition for all of Lindsay’s amazing efforts in scicom!!!
🙌🏼🔥🎉🤘🏽🫡🍾
🙌🏼🔥🎉🤘🏽🫡🍾
BEST DAY EVER!!! The award is called the Eric & Wendy Schmidt Award for Excellence in Science Communications & is run by @nationalacademies.org & @schmidtsciences.bsky.social #scicomm #phdstudent
November 18, 2025 at 2:08 PM
Check out this amazing recognition for all of Lindsay’s amazing efforts in scicom!!!
🙌🏼🔥🎉🤘🏽🫡🍾
🙌🏼🔥🎉🤘🏽🫡🍾
@sfn.org Come say hi to postdoc Blake Kimmey Tues, Nov. 18, 8:00 AM - 12:00 PM
PSTR278.07 - Convergent state-control of endogenous opioid analgesia
He's got new behavior/DREADD/Xenium data on PAG-to-thalamic circuits in pain/placebo/fear, building from his preprint: biorxiv.org/content/10.1...
PSTR278.07 - Convergent state-control of endogenous opioid analgesia
He's got new behavior/DREADD/Xenium data on PAG-to-thalamic circuits in pain/placebo/fear, building from his preprint: biorxiv.org/content/10.1...
November 17, 2025 at 5:47 PM
@sfn.org Come say hi to postdoc Blake Kimmey Tues, Nov. 18, 8:00 AM - 12:00 PM
PSTR278.07 - Convergent state-control of endogenous opioid analgesia
He's got new behavior/DREADD/Xenium data on PAG-to-thalamic circuits in pain/placebo/fear, building from his preprint: biorxiv.org/content/10.1...
PSTR278.07 - Convergent state-control of endogenous opioid analgesia
He's got new behavior/DREADD/Xenium data on PAG-to-thalamic circuits in pain/placebo/fear, building from his preprint: biorxiv.org/content/10.1...
Reposted by ⚡️GREG_CORDER⚡️
Sophie Rogers of the Corder @flybottleescape.bsky.social lab studies how a psychedelic drug with growing therapeutic promise can alter the brain in ways that help overcome traumatic fear memories. Read more in this brief by fellow NGG student Jafar Bhatti! www.upennglia.com/briefs/bib-p...
How psychedelics remap the brain to help overcome traumatic fear — GLIA
or technically, Psilocybin-enhanced fear extinction linked to bidirectional modulation of cortical ensembles [See original abstract on Pubmed]
www.upennglia.com
November 7, 2025 at 5:17 PM
Sophie Rogers of the Corder @flybottleescape.bsky.social lab studies how a psychedelic drug with growing therapeutic promise can alter the brain in ways that help overcome traumatic fear memories. Read more in this brief by fellow NGG student Jafar Bhatti! www.upennglia.com/briefs/bib-p...
Reposted by ⚡️GREG_CORDER⚡️
Thrilled to share that I’ll be joining the Perelman School of Medicine at the University of Pennsylvania! Our lab will be relocating to the Department of Pharmacology in Jan ’26. We’re hiring at all levels—reach out if you’re interested! @isbupenn.bsky.social @pennmedicine.bsky.social
September 28, 2025 at 9:32 PM
Thrilled to share that I’ll be joining the Perelman School of Medicine at the University of Pennsylvania! Our lab will be relocating to the Department of Pharmacology in Jan ’26. We’re hiring at all levels—reach out if you’re interested! @isbupenn.bsky.social @pennmedicine.bsky.social
Reposted by ⚡️GREG_CORDER⚡️
become my colleague at penn bioengineering: apply.interfolio.com/173716
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
September 19, 2025 at 2:29 AM
become my colleague at penn bioengineering: apply.interfolio.com/173716
Reposted by ⚡️GREG_CORDER⚡️
We could always get some re-interpretation language from NIH but at present the "council in a calendar year" is pretty dang clear. For 2026 Councils, we can submit six apps between May 2025 and March 2026.
September 18, 2025 at 7:20 PM
We could always get some re-interpretation language from NIH but at present the "council in a calendar year" is pretty dang clear. For 2026 Councils, we can submit six apps between May 2025 and March 2026.
🙏 Please help!
ad nauseam topic but for new NIH n=6 submission policy is it:
a. 6 subs in 2025 calendar year = we can sub 6 R01s for Oct '25 + another 6 for Jan-Dec '26?
b. subs in Oct '25 w/ May '26 Council = we can sub 6 R01s Oct '25 to June '26; count resets Oct '26?
ad nauseam topic but for new NIH n=6 submission policy is it:
a. 6 subs in 2025 calendar year = we can sub 6 R01s for Oct '25 + another 6 for Jan-Dec '26?
b. subs in Oct '25 w/ May '26 Council = we can sub 6 R01s Oct '25 to June '26; count resets Oct '26?
September 18, 2025 at 6:20 PM
🙏 Please help!
ad nauseam topic but for new NIH n=6 submission policy is it:
a. 6 subs in 2025 calendar year = we can sub 6 R01s for Oct '25 + another 6 for Jan-Dec '26?
b. subs in Oct '25 w/ May '26 Council = we can sub 6 R01s Oct '25 to June '26; count resets Oct '26?
ad nauseam topic but for new NIH n=6 submission policy is it:
a. 6 subs in 2025 calendar year = we can sub 6 R01s for Oct '25 + another 6 for Jan-Dec '26?
b. subs in Oct '25 w/ May '26 Council = we can sub 6 R01s Oct '25 to June '26; count resets Oct '26?
Reposted by ⚡️GREG_CORDER⚡️
(1/10) We’re excited to share our new preprint (doi.org/10.1101/2025...), which uncovers the spatiomolecular landscape of the human nucleus accumbens (NAc), by integrating snRNA-seq with Visium spatial transcriptomics across 10 control donors. 🧠 #NAcLIBD #snRNAseq #10xVisium
September 15, 2025 at 5:06 PM
(1/10) We’re excited to share our new preprint (doi.org/10.1101/2025...), which uncovers the spatiomolecular landscape of the human nucleus accumbens (NAc), by integrating snRNA-seq with Visium spatial transcriptomics across 10 control donors. 🧠 #NAcLIBD #snRNAseq #10xVisium
Reposted by ⚡️GREG_CORDER⚡️
Have you ever wondered how some of the leaders in the pain field got their start? Check out this essay from @painthejournal.bsky.social about PRF editorial board member, Allan Basbaum, to learn how he became the journal’s 3rd Editor-in-Chief bit.ly/3JIJTXf #PRF #PainAwarenessMonth
September 9, 2025 at 7:00 PM
Have you ever wondered how some of the leaders in the pain field got their start? Check out this essay from @painthejournal.bsky.social about PRF editorial board member, Allan Basbaum, to learn how he became the journal’s 3rd Editor-in-Chief bit.ly/3JIJTXf #PRF #PainAwarenessMonth
Reposted by ⚡️GREG_CORDER⚡️
My new essay for @thetransmitter.bsky.social. Why is understanding emotion so challenging? The debates around what counts as an "emotion" shed insight.
These disputes are multidimensional, principled and fascinating. Here, I unpack them.
www.thetransmitter.org/the-big-pict...
These disputes are multidimensional, principled and fascinating. Here, I unpack them.
www.thetransmitter.org/the-big-pict...
Emotion research has a communication conundrum
In 2025, the words we use to describe emotions matter, but their definitions are controversial. Here, I unpack the different positions in this space and the rationales behind them—and I invite 13…
www.thetransmitter.org
September 5, 2025 at 11:15 AM
My new essay for @thetransmitter.bsky.social. Why is understanding emotion so challenging? The debates around what counts as an "emotion" shed insight.
These disputes are multidimensional, principled and fascinating. Here, I unpack them.
www.thetransmitter.org/the-big-pict...
These disputes are multidimensional, principled and fascinating. Here, I unpack them.
www.thetransmitter.org/the-big-pict...
Reposted by ⚡️GREG_CORDER⚡️
What can *genetic insensitivity to opioids* teach us about endogenous opioid function in humans?
Fully funded position in Oslo (PhD student or postdoc)
Interested in pain, mu/kappa opioids, behavioural genetics, RCTs, or related? Apply here:
2411.webcruiter.no/Main2/Recrui...
Please RT for reach
Fully funded position in Oslo (PhD student or postdoc)
Interested in pain, mu/kappa opioids, behavioural genetics, RCTs, or related? Apply here:
2411.webcruiter.no/Main2/Recrui...
Please RT for reach
Phd candidate or postdoc– Genetic determinants of opioid responsiveness
The Department of Research and Development at the Division of Emergencies and Critical Care, Oslo University Hospital in collaboration with Leknes Affective Brain lab (www.affectivebrains.com) and the...
2411.webcruiter.no
August 29, 2025 at 2:20 PM
What can *genetic insensitivity to opioids* teach us about endogenous opioid function in humans?
Fully funded position in Oslo (PhD student or postdoc)
Interested in pain, mu/kappa opioids, behavioural genetics, RCTs, or related? Apply here:
2411.webcruiter.no/Main2/Recrui...
Please RT for reach
Fully funded position in Oslo (PhD student or postdoc)
Interested in pain, mu/kappa opioids, behavioural genetics, RCTs, or related? Apply here:
2411.webcruiter.no/Main2/Recrui...
Please RT for reach
I’m going to present on LUPE — our deep-learning system for automated pain behavior analysis — and the Affective-Motivational Pain Scale (AMPS) model for quantifying complex pain states
📄 Preprint: www.biorxiv.org/content/10.1...
💻 Analysis package: github.com/justin05423/...
📄 Preprint: www.biorxiv.org/content/10.1...
💻 Analysis package: github.com/justin05423/...
Are you curious about headache and migraine pain? Join the Gulf Coast Consortium for a deep dive into the world of headaches and migraines at the #Pain2025 Workshop, featuring talks from @moeneuro.bsky.social, Yarimar Carrasquillo, and Greg Corder bit.ly/3JaeHzL #PRF
August 11, 2025 at 7:49 PM
I’m going to present on LUPE — our deep-learning system for automated pain behavior analysis — and the Affective-Motivational Pain Scale (AMPS) model for quantifying complex pain states
📄 Preprint: www.biorxiv.org/content/10.1...
💻 Analysis package: github.com/justin05423/...
📄 Preprint: www.biorxiv.org/content/10.1...
💻 Analysis package: github.com/justin05423/...
Reposted by ⚡️GREG_CORDER⚡️
A new study pinpoints an emotion-to-motivation gateway that converts painful signals into negative feelings, offering a promising target for non-opioid pain relief.
Learn more in this week’s issue of #ScienceAdvances: scim.ag/46jefZE
Learn more in this week’s issue of #ScienceAdvances: scim.ag/46jefZE
July 25, 2025 at 8:02 PM
A new study pinpoints an emotion-to-motivation gateway that converts painful signals into negative feelings, offering a promising target for non-opioid pain relief.
Learn more in this week’s issue of #ScienceAdvances: scim.ag/46jefZE
Learn more in this week’s issue of #ScienceAdvances: scim.ag/46jefZE
Reposted by ⚡️GREG_CORDER⚡️
So excited to have been part of this work from the Corder lab! Congrats to Jess and the whole team.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
A nociceptive amygdala-striatal pathway modulating affective-motivational pain
A nociceptive basolateral amygdala–to–nucleus accumbens shell circuit contributes to pain unpleasantness in chronic pain.
www.science.org
July 24, 2025 at 12:25 AM
So excited to have been part of this work from the Corder lab! Congrats to Jess and the whole team.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
⚡️🧠A nociceptive amygdala-striatal pathway modulating affective-motivational pain
Now published on the cover of Science Advances @science.org
Check it out 👇
www.science.org/doi/10.1126/...
Now published on the cover of Science Advances @science.org
Check it out 👇
www.science.org/doi/10.1126/...
July 23, 2025 at 6:52 PM
⚡️🧠A nociceptive amygdala-striatal pathway modulating affective-motivational pain
Now published on the cover of Science Advances @science.org
Check it out 👇
www.science.org/doi/10.1126/...
Now published on the cover of Science Advances @science.org
Check it out 👇
www.science.org/doi/10.1126/...
Reposted by ⚡️GREG_CORDER⚡️
Happy 107th Birthday, Brenda Milner! Her contributions to neuropsychology shaped the way we understand the human brain. From surviving two world wars and two pandemics, to paving the way for future generations of researchers, Milner’s legacy continues. @mcgill.ca @cusm-muhc.bsky.social
July 15, 2025 at 2:05 PM
Happy 107th Birthday, Brenda Milner! Her contributions to neuropsychology shaped the way we understand the human brain. From surviving two world wars and two pandemics, to paving the way for future generations of researchers, Milner’s legacy continues. @mcgill.ca @cusm-muhc.bsky.social
Reposted by ⚡️GREG_CORDER⚡️
Excited to see this finally out! Projection-TAGs allows you to do multiplex high-throughput multi-modal profiling of projection neurons. www.nature.com/articles/s41...
Projection-TAGs enable multiplex projection tracing and multi-modal profiling of projection neurons - Nature Communications
Tools to simultaneously trace multiple neuronal projections and/or profile projection neurons for multi-modal investigations are lacking. Here authors introduce Projection-TAGs, a retrograde AAV platf...
www.nature.com
July 2, 2025 at 8:52 PM
Excited to see this finally out! Projection-TAGs allows you to do multiplex high-throughput multi-modal profiling of projection neurons. www.nature.com/articles/s41...
Reposted by ⚡️GREG_CORDER⚡️
I am happy to share that I’ve been awarded tenure here at Columbia University. Alhamdulillah. I thank my wife, parents, mentors, colleagues, friends, and family. I thank my lab members, present and past, for entrusting their careers in my hands and making this a thrilling journey.
July 2, 2025 at 1:43 PM
I am happy to share that I’ve been awarded tenure here at Columbia University. Alhamdulillah. I thank my wife, parents, mentors, colleagues, friends, and family. I thank my lab members, present and past, for entrusting their careers in my hands and making this a thrilling journey.
Huge congrats to Dr. Lisa Wooldridge!
She crushed her PhD defense on central amygdala circuits in opioid dependence
Incredible science, relentless rigor, and a fearless approach to tough questions
So proud to be part of your journey, Lisa!
🧠🔥🎓🍾
She crushed her PhD defense on central amygdala circuits in opioid dependence
Incredible science, relentless rigor, and a fearless approach to tough questions
So proud to be part of your journey, Lisa!
🧠🔥🎓🍾
July 1, 2025 at 11:35 PM
Huge congrats to Dr. Lisa Wooldridge!
She crushed her PhD defense on central amygdala circuits in opioid dependence
Incredible science, relentless rigor, and a fearless approach to tough questions
So proud to be part of your journey, Lisa!
🧠🔥🎓🍾
She crushed her PhD defense on central amygdala circuits in opioid dependence
Incredible science, relentless rigor, and a fearless approach to tough questions
So proud to be part of your journey, Lisa!
🧠🔥🎓🍾
Met w student in morning to discuss “time tiling” in imaging across fear conditioning
Saw this new paper in the evening, sent to student
Woke up to student’s reanalysis using open-source code from this paper …
= retrosplineal drift with sharp jumps at tone+shock pairings vs extinction tones
Saw this new paper in the evening, sent to student
Woke up to student’s reanalysis using open-source code from this paper …
= retrosplineal drift with sharp jumps at tone+shock pairings vs extinction tones
June 27, 2025 at 1:04 PM
Met w student in morning to discuss “time tiling” in imaging across fear conditioning
Saw this new paper in the evening, sent to student
Woke up to student’s reanalysis using open-source code from this paper …
= retrosplineal drift with sharp jumps at tone+shock pairings vs extinction tones
Saw this new paper in the evening, sent to student
Woke up to student’s reanalysis using open-source code from this paper …
= retrosplineal drift with sharp jumps at tone+shock pairings vs extinction tones
🤮 more garbage takes in grant reviews .. we got a 5 and ultimately ND bc we have papers on bioRxiv that were to support the 20+ references for ACC/PAG/BLA roles in pain
.. punished for preprints, wtf
.. punished for preprints, wtf
June 26, 2025 at 6:53 PM
🤮 more garbage takes in grant reviews .. we got a 5 and ultimately ND bc we have papers on bioRxiv that were to support the 20+ references for ACC/PAG/BLA roles in pain
.. punished for preprints, wtf
.. punished for preprints, wtf
im also an alzheimer's researcher now too ... 😜
angry CD68+ microglia eating some X-34 dyed plaques
angry CD68+ microglia eating some X-34 dyed plaques
June 23, 2025 at 7:16 PM
im also an alzheimer's researcher now too ... 😜
angry CD68+ microglia eating some X-34 dyed plaques
angry CD68+ microglia eating some X-34 dyed plaques
Reposted by ⚡️GREG_CORDER⚡️
How can one be so bad at their job and more generally at reading the room scientifically at so many levels. @_@
June 20, 2025 at 3:28 AM
How can one be so bad at their job and more generally at reading the room scientifically at so many levels. @_@
Reposted by ⚡️GREG_CORDER⚡️
Would be nice if reviewers also took into account our current funding situation and not ask for these types of extensive revisions that cost $$$ that doesn't exist 🤷♀️
June 19, 2025 at 9:51 PM
Would be nice if reviewers also took into account our current funding situation and not ask for these types of extensive revisions that cost $$$ that doesn't exist 🤷♀️