ethan whitman
@ethanwhitman777.bsky.social
phd student at duke with moffitt/caspi + laboratory of neurogenetics using predictive modeling to understand brain aging
Pinned
DunedinPACNI estimates the longitudinal Pace of Aging from a single brain image to track health and disease - Nature Aging
Differences in the Pace of Aging are important for many health outcomes but difficult to measure. Here the authors describe the Dunedin Pace of Aging Calculated from NeuroImaging measure, an approach ...
www.nature.com
Now published in @nataging.nature.com ! We propose DunedinPACNI, a new measure of the rate of aging that can be derived from a single structural brain scan www.nature.com/articles/s43...
Reposted by ethan whitman
🔥🔥🧠PhD positions are open in my lab, studying brain development and neurodevelopmental disorders based on neuroimaging MRI scans. Due: Dec 1, 2025. If you are interested, please DM me.
October 21, 2025 at 7:53 PM
🔥🔥🧠PhD positions are open in my lab, studying brain development and neurodevelopmental disorders based on neuroimaging MRI scans. Due: Dec 1, 2025. If you are interested, please DM me.
Reposted by ethan whitman
My second first author paper of graduate school - Sex differences in response to violence: role of salience network expansion and connectivity on depression - is now published in Translational Psychiatry! rdcu.be/eLYg6
Sex differences in response to violence: role of salience network expansion and connectivity on depression
Translational Psychiatry - Sex differences in response to violence: role of salience network expansion and connectivity on depression
rdcu.be
October 21, 2025 at 8:43 PM
My second first author paper of graduate school - Sex differences in response to violence: role of salience network expansion and connectivity on depression - is now published in Translational Psychiatry! rdcu.be/eLYg6
Reposted by ethan whitman
Official job ad is up! careers.peopleclick.com/careerscp/cl...
October 15, 2025 at 3:51 PM
Official job ad is up! careers.peopleclick.com/careerscp/cl...
Reposted by ethan whitman
Our new paper is out now in Neuron! 🎉 With @vaibhavtripathi.bsky.social @maxwellelliott.bsky.social Joanna Ladopoulou, Wendy Sun, Mark Eldaief, and Randy Buckner
Paper link: www.sciencedirect.com/science/arti...
Paper link: www.sciencedirect.com/science/arti...
September 26, 2025 at 3:25 PM
Our new paper is out now in Neuron! 🎉 With @vaibhavtripathi.bsky.social @maxwellelliott.bsky.social Joanna Ladopoulou, Wendy Sun, Mark Eldaief, and Randy Buckner
Paper link: www.sciencedirect.com/science/arti...
Paper link: www.sciencedirect.com/science/arti...
Reposted by ethan whitman
Delighted to see the paper describing the Reproducible Brain Charts open data resource now out in @cp-neuron.bsky.social. Paper + link to data below; huge congrats to @goliashf.bsky.social @milhammichael.bsky.social and the whole RBC team. Lots of people (>2,500 downloads) are already using RBC!
September 24, 2025 at 1:23 PM
Delighted to see the paper describing the Reproducible Brain Charts open data resource now out in @cp-neuron.bsky.social. Paper + link to data below; huge congrats to @goliashf.bsky.social @milhammichael.bsky.social and the whole RBC team. Lots of people (>2,500 downloads) are already using RBC!
Reposted by ethan whitman
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
July 17, 2025 at 1:36 AM
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
Reposted by ethan whitman
Network analysis offers new insights into psychiatric symptoms. How can we use these tools to compare symptom patterns across groups?
⬇️🧵Thread below 🧵⬇️
doi.org/10.1017/s003...
⬇️🧵Thread below 🧵⬇️
doi.org/10.1017/s003...
Novel tools for comparing the architecture of psychopathology between neurogenetic disorders: An application to X- versus Y-chromosome aneuploidy effects in males | Psychological Medicine | Cambridge ...
Novel tools for comparing the architecture of psychopathology between neurogenetic disorders: An application to X- versus Y-chromosome aneuploidy effects in males - Volume 55
doi.org
July 3, 2025 at 9:48 PM
Network analysis offers new insights into psychiatric symptoms. How can we use these tools to compare symptom patterns across groups?
⬇️🧵Thread below 🧵⬇️
doi.org/10.1017/s003...
⬇️🧵Thread below 🧵⬇️
doi.org/10.1017/s003...
Reposted by ethan whitman
Do you want to estimate brain aging from a single MRI scan?
Check out our latest work in Nature Aging
"DunedinPACNI estimates the longitudinal Pace of Aging from a single brain image to track health and disease"
Check out our latest work in Nature Aging
"DunedinPACNI estimates the longitudinal Pace of Aging from a single brain image to track health and disease"
July 7, 2025 at 7:21 PM
Do you want to estimate brain aging from a single MRI scan?
Check out our latest work in Nature Aging
"DunedinPACNI estimates the longitudinal Pace of Aging from a single brain image to track health and disease"
Check out our latest work in Nature Aging
"DunedinPACNI estimates the longitudinal Pace of Aging from a single brain image to track health and disease"
Reposted by ethan whitman
Sex chromosome aneuploidies (varying X/Y-chrom dosage) can increase risk for psychopathology, but do these risks vary with age ? This matters for both clinical and mechanistic understanding.
A fab recent trainee - Melissa Roybal - asked these questions in a new paper. This is what she found ... ⬇️
A fab recent trainee - Melissa Roybal - asked these questions in a new paper. This is what she found ... ⬇️
July 7, 2025 at 1:01 PM
Sex chromosome aneuploidies (varying X/Y-chrom dosage) can increase risk for psychopathology, but do these risks vary with age ? This matters for both clinical and mechanistic understanding.
A fab recent trainee - Melissa Roybal - asked these questions in a new paper. This is what she found ... ⬇️
A fab recent trainee - Melissa Roybal - asked these questions in a new paper. This is what she found ... ⬇️
Reposted by ethan whitman
Telltale features visible in standard brain images can reveal how quickly a person is ageing
https://go.nature.com/4kiNEPF
https://go.nature.com/4kiNEPF
How fast is your brain ageing? Ordinary scans reveal the pace
Images hold clues to risk of dementia and various age-related diseases.
go.nature.com
July 1, 2025 at 12:06 PM
Telltale features visible in standard brain images can reveal how quickly a person is ageing
https://go.nature.com/4kiNEPF
https://go.nature.com/4kiNEPF
Now published in @nataging.nature.com ! We propose DunedinPACNI, a new measure of the rate of aging that can be derived from a single structural brain scan www.nature.com/articles/s43...
DunedinPACNI estimates the longitudinal Pace of Aging from a single brain image to track health and disease - Nature Aging
Differences in the Pace of Aging are important for many health outcomes but difficult to measure. Here the authors describe the Dunedin Pace of Aging Calculated from NeuroImaging measure, an approach ...
www.nature.com
July 1, 2025 at 2:59 PM
Now published in @nataging.nature.com ! We propose DunedinPACNI, a new measure of the rate of aging that can be derived from a single structural brain scan www.nature.com/articles/s43...
Reposted by ethan whitman
New preprint!!!
We can reliably detect brain changes in individuals in just a year by collecting several rapid 1-minute T1s at each time point - i.e. "cluster scanning". We discovered large individual differences, even in healthy adults
t.co/oxD9EBdbvu
We can reliably detect brain changes in individuals in just a year by collecting several rapid 1-minute T1s at each time point - i.e. "cluster scanning". We discovered large individual differences, even in healthy adults
t.co/oxD9EBdbvu
https://www.medrxiv.org/content/10.1101/2025.02.21.25322553v1
t.co
February 26, 2025 at 5:16 PM
New preprint!!!
We can reliably detect brain changes in individuals in just a year by collecting several rapid 1-minute T1s at each time point - i.e. "cluster scanning". We discovered large individual differences, even in healthy adults
t.co/oxD9EBdbvu
We can reliably detect brain changes in individuals in just a year by collecting several rapid 1-minute T1s at each time point - i.e. "cluster scanning". We discovered large individual differences, even in healthy adults
t.co/oxD9EBdbvu
Reposted by ethan whitman
🚨 Brain Age vs Direct Models in Alzheimer’s disease (AD) 🚨 A thread 🧵
1/ Brain age is a powerful indicator of general brain health, trained on massive datasets. But does this translate to better prediction for specific outcomes, like AD?
Preprint by @twktan.bsky.social : doi.org/10.1101/2024...
1/ Brain age is a powerful indicator of general brain health, trained on massive datasets. But does this translate to better prediction for specific outcomes, like AD?
Preprint by @twktan.bsky.social : doi.org/10.1101/2024...
November 20, 2024 at 3:06 AM
🚨 Brain Age vs Direct Models in Alzheimer’s disease (AD) 🚨 A thread 🧵
1/ Brain age is a powerful indicator of general brain health, trained on massive datasets. But does this translate to better prediction for specific outcomes, like AD?
Preprint by @twktan.bsky.social : doi.org/10.1101/2024...
1/ Brain age is a powerful indicator of general brain health, trained on massive datasets. But does this translate to better prediction for specific outcomes, like AD?
Preprint by @twktan.bsky.social : doi.org/10.1101/2024...
some people age faster than others – but how should we measure it?
excited to share our preprint where we propose a new measure of the rate of biological aging that can be derived from a single structural brain scan
posted to twitter a while ago...now on here too !
www.biorxiv.org/content/10.1...
excited to share our preprint where we propose a new measure of the rate of biological aging that can be derived from a single structural brain scan
posted to twitter a while ago...now on here too !
www.biorxiv.org/content/10.1...
An estimate of the longitudinal pace of aging from a single brain scan predicts dementia conversion, morbidity, and mortality
To understand how aging affects functional decline and increases disease risk, it is necessary to develop accurate and reliable measures of how fast a person is aging. Epigenetic clocks measure aging ...
www.biorxiv.org
November 18, 2024 at 7:20 PM
some people age faster than others – but how should we measure it?
excited to share our preprint where we propose a new measure of the rate of biological aging that can be derived from a single structural brain scan
posted to twitter a while ago...now on here too !
www.biorxiv.org/content/10.1...
excited to share our preprint where we propose a new measure of the rate of biological aging that can be derived from a single structural brain scan
posted to twitter a while ago...now on here too !
www.biorxiv.org/content/10.1...