Tatiana Engel
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engeltatiana.bsky.social
Tatiana Engel
@engeltatiana.bsky.social
Computational neuroscientist @princetonneuro.bsky.social deciphering natural and advancing artificial intelligence.
Pinned
Out today in @nature.com: we show that individual neurons have diverse tuning to a decision variable computed by the entire population, revealing a unifying geometric principle for the encoding of sensory and dynamic cognitive variables.
www.nature.com/articles/s41...
Our work with @pawa-pawa.bsky.social is out in Nature Machine Intelligence! The choice of activation function affects the representations, dynamics, and circuit solutions that emerge in RNNs trained on cognitive tasks. Activation matters!
www.nature.com/articles/s42...
October 24, 2025 at 7:18 PM
A study led by Cina Aghamohammadi is now out in ‪@natcomms.nature.com‬! We developed a mathematical framework for partitioning spiking variability, which revealed that spiking irregularity is nearly invariant for each neuron and decreases along the cortical hierarchy.
www.nature.com/articles/s41...
October 12, 2025 at 12:42 AM
Reposted by Tatiana Engel
Two flagship papers from the International Brain Laboratory, now out in ‪@Nature.com‬:
🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0
🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +
September 3, 2025 at 4:22 PM
Reposted by Tatiana Engel
Princeton’s @ilanawitten.bsky.social, @engeltatiana.bsky.social, and @jpillowtime.bsky.social have created the first-ever brain-wide activity map during decision making in mice as part of an international group effort known as the @intlbrainlab.bsky.social.

🔗 pni.princeton.edu/news/2025/fi...
September 3, 2025 at 3:17 PM
New work with @shiyanliang.bsky.social‬, @roxana-zeraati.bsky.social, @intlbrainlab.bsky.social, Anna Levina. We uncover the principles that organize single-neuron timescales across the entire brain, unifying regional specialization with universal brain-wide dynamics: www.biorxiv.org/content/10.1...
Excited to share our new preprint on the brain-wide organization of intrinsic timescales at single neuron resolution. Work w/ @roxana-zeraati.bsky.social, @intlbrainlab.bsky.social, Anna Levina, @engeltatiana.bsky.social : www.biorxiv.org/content/10.1...
September 2, 2025 at 4:08 PM
Out today in @nature.com: we show that individual neurons have diverse tuning to a decision variable computed by the entire population, revealing a unifying geometric principle for the encoding of sensory and dynamic cognitive variables.
www.nature.com/articles/s41...
June 25, 2025 at 10:38 PM
Reposted by Tatiana Engel
“Like a group of skiers descending a mountain, each [neuron] prefers a slightly different path, but all are shaped by the same slope,” says PNI's @engeltatiana.bsky.social‬ on her lab’s new ‪@nature.com‬ study revealing how the brain makes decisions.

📰: pni.princeton.edu/news/2025/al...
June 25, 2025 at 3:06 PM
Reposted by Tatiana Engel
Into population dynamics? Coming to #CNS2025 but not quite ready to head home?

Come join us! at the Symposium on "Neural Population Dynamics and Latent Representations"! 🧠
📆 July 10th
📍 Scuola Superiore Sant’Anna, Pisa (and online)
👉 Free registration: neurobridge-tne.github.io
#compneuro
June 21, 2025 at 10:24 AM
Our new paper with @chrismlangdon is just out in @natureneuro.bsky.social! We show that high-dimensional RNNs use low-dimensional circuit mechanisms for cognitive tasks and identify a latent inhibitory mechanism for context-dependent decisions in PFC data.
www.nature.com/articles/s41...
February 12, 2025 at 6:19 PM
Reposted by Tatiana Engel
The latent circuit model identifies low-dimensional mechanisms of task execution from heterogeneous neural responses. This approach revealed a latent inhibitory mechanism for context-dependent decisions in neural network models and prefrontal cortex 🧪🧠

www.nature.com/articles/s41...
Latent circuit inference from heterogeneous neural responses during cognitive tasks - Nature Neuroscience
The latent circuit model identifies low-dimensional mechanisms of task execution from heterogenous neural responses. This approach reveals a latent inhibitory mechanism for context-dependent decisions...
www.nature.com
February 11, 2025 at 11:53 AM