Elizabeth Manning
@emmanning.bsky.social
Forebrain development, hypothalamus patterning, early morphogenesis. Postdoctoral Researcher with Marysia Placzek at The University of Sheffield
Excited to finally share the final/final.doc version of our paper. It's been a journey, but very proud of the result. Well done to all involved, especially @elsieplace.bsky.social
@kchinnaiya.bsky.social , @thomasdwkim.bsky.social, @sethblackshaw.bsky.social 👏👏
www.nature.com/articles/s41...
@kchinnaiya.bsky.social , @thomasdwkim.bsky.social, @sethblackshaw.bsky.social 👏👏
www.nature.com/articles/s41...
Resolving forebrain developmental organisation by analysis of differential growth patterns - Nature Communications
Experiments on the embryonic chick brain reveal distinct directional growth patterns and a tripartite hypothalamus, challenging the classic segmented prosomere model and offering an updated view of ho...
www.nature.com
January 26, 2026 at 10:23 AM
Excited to finally share the final/final.doc version of our paper. It's been a journey, but very proud of the result. Well done to all involved, especially @elsieplace.bsky.social
@kchinnaiya.bsky.social , @thomasdwkim.bsky.social, @sethblackshaw.bsky.social 👏👏
www.nature.com/articles/s41...
@kchinnaiya.bsky.social , @thomasdwkim.bsky.social, @sethblackshaw.bsky.social 👏👏
www.nature.com/articles/s41...
Very happy to share our latest article in @natcomms.nature.com !
Also very pleased to be a featured article (beautiful artwork from @elsieplace.bsky.social depicting early chick neurectoderms at increasing stages of development. (waiting patiently in space for the right moment to attack the Earth?)
Also very pleased to be a featured article (beautiful artwork from @elsieplace.bsky.social depicting early chick neurectoderms at increasing stages of development. (waiting patiently in space for the right moment to attack the Earth?)
New featured article!
Resolving forebrain developmental organisation by analysis of differential growth patterns
@emmanning.bsky.social @elsieplace.bsky.social @kchinnaiya.bsky.social @sethblackshaw.bsky.social @thomasdwkim.bsky.social
http://dlvr.it/TQLWh5
Resolving forebrain developmental organisation by analysis of differential growth patterns
@emmanning.bsky.social @elsieplace.bsky.social @kchinnaiya.bsky.social @sethblackshaw.bsky.social @thomasdwkim.bsky.social
http://dlvr.it/TQLWh5
January 15, 2026 at 12:48 PM
Very happy to share our latest article in @natcomms.nature.com !
Also very pleased to be a featured article (beautiful artwork from @elsieplace.bsky.social depicting early chick neurectoderms at increasing stages of development. (waiting patiently in space for the right moment to attack the Earth?)
Also very pleased to be a featured article (beautiful artwork from @elsieplace.bsky.social depicting early chick neurectoderms at increasing stages of development. (waiting patiently in space for the right moment to attack the Earth?)
A very good, entertaining and frankly terrifying look at neural networks and AI
www.youtube.com/watch?v=jrK3...
www.youtube.com/watch?v=jrK3...
AI: What Could Go Wrong? with Geoffrey Hinton | The Weekly Show with Jon Stewart
YouTube video by The Weekly Show with Jon Stewart
www.youtube.com
October 25, 2025 at 1:42 PM
A very good, entertaining and frankly terrifying look at neural networks and AI
www.youtube.com/watch?v=jrK3...
www.youtube.com/watch?v=jrK3...
Reposted by Elizabeth Manning
“Developmental biology is fundamentally beautiful. We are no less beautiful for our variation. Instead, perhaps we are more so. Perhaps we are remarkable. Perhaps we are full of wonder.”
Read this insightful post by Bethan on the Node.
thenode.biologists.com/developmenta...
#Disability
Read this insightful post by Bethan on the Node.
thenode.biologists.com/developmenta...
#Disability
Developmental Biology and Disability - the Node
Hopeful monsters. Morphospace. Mutation. Natural variation. Mutagenesis screens. Polymorphism. Deformity. Phenotype. Disease. Adaptation. Anomaly.
thenode.biologists.com
October 22, 2025 at 1:15 PM
“Developmental biology is fundamentally beautiful. We are no less beautiful for our variation. Instead, perhaps we are more so. Perhaps we are remarkable. Perhaps we are full of wonder.”
Read this insightful post by Bethan on the Node.
thenode.biologists.com/developmenta...
#Disability
Read this insightful post by Bethan on the Node.
thenode.biologists.com/developmenta...
#Disability
Looking forward to the #biologists100 conference in Liverpool next week!
I’m creating a thread below to link to my poster (in collaboration with @elsieplace.bsky.social) so we can share our 4D model of forebrain development.
Come visit us: Poster 200, Session 2 on Wednesday.
I’m creating a thread below to link to my poster (in collaboration with @elsieplace.bsky.social) so we can share our 4D model of forebrain development.
Come visit us: Poster 200, Session 2 on Wednesday.
March 20, 2025 at 10:59 AM
Looking forward to the #biologists100 conference in Liverpool next week!
I’m creating a thread below to link to my poster (in collaboration with @elsieplace.bsky.social) so we can share our 4D model of forebrain development.
Come visit us: Poster 200, Session 2 on Wednesday.
I’m creating a thread below to link to my poster (in collaboration with @elsieplace.bsky.social) so we can share our 4D model of forebrain development.
Come visit us: Poster 200, Session 2 on Wednesday.
Reposted by Elizabeth Manning
Need to electroporate and/or live image avian embryos? We hope our new preprint will help you get started:
www.biorxiv.org/content/10.1...
Open EGGbox: an open-source 3D-printed embryonic Gallus gallus toolbox for electroporation and culture/live imaging of avian embryos ex ovo
🧪🐣 #devbio
www.biorxiv.org/content/10.1...
Open EGGbox: an open-source 3D-printed embryonic Gallus gallus toolbox for electroporation and culture/live imaging of avian embryos ex ovo
🧪🐣 #devbio
March 6, 2025 at 2:28 PM
Need to electroporate and/or live image avian embryos? We hope our new preprint will help you get started:
www.biorxiv.org/content/10.1...
Open EGGbox: an open-source 3D-printed embryonic Gallus gallus toolbox for electroporation and culture/live imaging of avian embryos ex ovo
🧪🐣 #devbio
www.biorxiv.org/content/10.1...
Open EGGbox: an open-source 3D-printed embryonic Gallus gallus toolbox for electroporation and culture/live imaging of avian embryos ex ovo
🧪🐣 #devbio
Reposted by Elizabeth Manning
This is a profoundly evil betrayal and a direct reflection of Trump's soul—a disgusting, small, and shameful ghoul who gets off on harming the powerless.
www.reuters.com/world/us/tru...
www.reuters.com/world/us/tru...
Exclusive: Trump plans to revoke legal status of Ukrainians who fled to US, sources say
U.S. President Donald Trump's administration is planning to revoke temporary legal status for some 240,000 Ukrainians who fled the conflict with Russia, a senior Trump official and three sources familiar with the matter said, potentially putting them on a fast-track to deportation.
www.reuters.com
March 6, 2025 at 1:11 PM
This is a profoundly evil betrayal and a direct reflection of Trump's soul—a disgusting, small, and shameful ghoul who gets off on harming the powerless.
www.reuters.com/world/us/tru...
www.reuters.com/world/us/tru...
Reposted by Elizabeth Manning
New! 15y after the classic Aigouy et al "Cell Flow Reorients the Axis of Planar Polarity in the Wing Epithelium..." from lab of much missed Suzanne Eaton, we provide our take from post-doc Sara Tan "Tissue shear as a cue for aligning planar polarity in the developing Drosophila wing".
rdcu.be/d81Vn
rdcu.be/d81Vn
February 8, 2025 at 4:46 PM
New! 15y after the classic Aigouy et al "Cell Flow Reorients the Axis of Planar Polarity in the Wing Epithelium..." from lab of much missed Suzanne Eaton, we provide our take from post-doc Sara Tan "Tissue shear as a cue for aligning planar polarity in the developing Drosophila wing".
rdcu.be/d81Vn
rdcu.be/d81Vn
Sunrise over Sheffield
January 22, 2025 at 9:12 PM
Sunrise over Sheffield
Check out our fabulous 4D model of forebrain development, created in Blender from imported light sheet scans of HH10-20 dissected chick neuroepithelium, and painstakingly linked together by @elsieplace.bsky.social by combining published fate maps with 100's of our own samples.
January 13, 2025 at 4:02 PM
Check out our fabulous 4D model of forebrain development, created in Blender from imported light sheet scans of HH10-20 dissected chick neuroepithelium, and painstakingly linked together by @elsieplace.bsky.social by combining published fate maps with 100's of our own samples.
Reposted by Elizabeth Manning
Excited to present our new preprint clarifying forebrain developmental organisation. Complex growth patterns shape the forebrain but distort the A-P + D-V axes, hence prior confusion over brain layout. Big love for chicken embryos, simpler to interpret than mouse 🐣1/3 www.biorxiv.org/content/10.1...
Resolving forebrain developmental organisation by analysis of differential growth patterns
The forebrain is the most complex region of the vertebrate CNS, and its developmental organisation is controversial. We fate-mapped the embryonic chick forebrain using lipophilic dyes and Cre-recombin...
www.biorxiv.org
January 13, 2025 at 3:36 PM
Excited to present our new preprint clarifying forebrain developmental organisation. Complex growth patterns shape the forebrain but distort the A-P + D-V axes, hence prior confusion over brain layout. Big love for chicken embryos, simpler to interpret than mouse 🐣1/3 www.biorxiv.org/content/10.1...
Great work from @thomasdwkim.bsky.social and @sethblackshaw.bsky.social labs
Our second preprint, which was spearheaded by @thomasdwkim.bsky.social, uses single-cell multiomic analysis to identify gene regulatory networks controlling neurogenesis and cell fate specification in mouse hypothalamus and prethalamus./1
biorxiv.org/cgi/content/...
biorxiv.org/cgi/content/...
January 13, 2025 at 9:11 AM
Great work from @thomasdwkim.bsky.social and @sethblackshaw.bsky.social labs
Reposted by Elizabeth Manning
We begin the New Year with two preprints on hypothalamic development. The first, part of a long-term collaboration with Marysia Placzek’s group, investigates the organization of the developing forebrain, and show that current models are (mostly) incorrect./1
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Resolving forebrain developmental organisation by analysis of differential growth patterns
The forebrain is the most complex region of the vertebrate CNS, and its developmental organisation is controversial. We fate-mapped the embryonic chick forebrain using lipophilic dyes and Cre-recombin...
www.biorxiv.org
January 11, 2025 at 11:36 PM
We begin the New Year with two preprints on hypothalamic development. The first, part of a long-term collaboration with Marysia Placzek’s group, investigates the organization of the developing forebrain, and show that current models are (mostly) incorrect./1
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Excited to share our new preprint:
Resolving forebrain developmental organisation by analysis of differential growth patterns https://www.biorxiv.org/content/10.1101/2025.01.10.632351v1
January 11, 2025 at 3:59 PM
Excited to share our new preprint: