Erin Aboelnour, Ph.D.
@eaboelno.bsky.social
Postdoc studying the role of neural stem cells in regeneration and MS
Dr. Katrina Adams lab, University of Notre Dame 🍀 (she/her)
🔬🧬👟⚽️♥️
Dr. Katrina Adams lab, University of Notre Dame 🍀 (she/her)
🔬🧬👟⚽️♥️
Reposted by Erin Aboelnour, Ph.D.
New preprint from our lab. Led by the outstanding @anitaada.bsky.social and @raquelgarza.bsky.social. Funded by @asapresearch.bsky.social and @vetenskapsradet.bsky.social.
LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development
www.biorxiv.org/content/10.1...
LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development
www.biorxiv.org/content/10.1...
LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development
Long interspersed nuclear element 1 (L1) retrotransposons represent a vast source of divergent genetic information. However, mechanistic analysis of whether and how L1s contribute to human development...
www.biorxiv.org
January 18, 2025 at 8:58 AM
New preprint from our lab. Led by the outstanding @anitaada.bsky.social and @raquelgarza.bsky.social. Funded by @asapresearch.bsky.social and @vetenskapsradet.bsky.social.
LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development
www.biorxiv.org/content/10.1...
LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development
www.biorxiv.org/content/10.1...
Reposted by Erin Aboelnour, Ph.D.
New paper out from the lab! Led by @gdfnunes.bsky.social and Lindsay Osso in collaboration with the lab of Dan Denman. Check it out! 🔬 🐭 🧠
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Incomplete remyelination via therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function - Nature Communications
Remyelination can restore neural function. Here, the authors characterize the drivers and limits of endogenous remyelination and explore a therapy that rescued remyelination deficits and accelerated n...
www.nature.com
January 18, 2025 at 6:41 PM
New paper out from the lab! Led by @gdfnunes.bsky.social and Lindsay Osso in collaboration with the lab of Dan Denman. Check it out! 🔬 🐭 🧠
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Erin Aboelnour, Ph.D.
Excited to share our new work identifying PKC as a druggable target for modulating microglia in order to enhance myelin repair. 🧵 #remyelination #multiplesclerosis www.science.org/doi/10.1126/...
The protein kinase C modulator bryostatin-1 therapeutically targets microglia to attenuate neuroinflammation and promote remyelination
Protein kinase C modulation with bryostatin-1 enables innate immune cells in the central nervous system to promote myelin repair and regeneration.
www.science.org
January 8, 2025 at 7:49 PM
Excited to share our new work identifying PKC as a druggable target for modulating microglia in order to enhance myelin repair. 🧵 #remyelination #multiplesclerosis www.science.org/doi/10.1126/...
Reposted by Erin Aboelnour, Ph.D.
Modeling the acutely injured brain environment in vitro. https://www.biorxiv.org/content/10.1101/2025.01.08.631921v1
January 8, 2025 at 7:15 PM
Modeling the acutely injured brain environment in vitro. https://www.biorxiv.org/content/10.1101/2025.01.08.631921v1
Reposted by Erin Aboelnour, Ph.D.
Excellent work by @liwangneuro.bsky.social
Arnold Kriegstein and colleagues, deepening our understanding of the molecular and cellular dynamics of the developing human neocortex. The identification of a tripotential intermediate progenitor subtype is a key finding 🧪🧠🧬
www.nature.com/articles/s41...
Arnold Kriegstein and colleagues, deepening our understanding of the molecular and cellular dynamics of the developing human neocortex. The identification of a tripotential intermediate progenitor subtype is a key finding 🧪🧠🧬
www.nature.com/articles/s41...
Molecular and cellular dynamics of the developing human neocortex - Nature
Tripotential intermediate progenitor cells are responsible for the local production of GABAergic neurons, oligodendrocyte precursor cells and astrocytes in the human neocortex.
www.nature.com
January 9, 2025 at 9:16 AM
Excellent work by @liwangneuro.bsky.social
Arnold Kriegstein and colleagues, deepening our understanding of the molecular and cellular dynamics of the developing human neocortex. The identification of a tripotential intermediate progenitor subtype is a key finding 🧪🧠🧬
www.nature.com/articles/s41...
Arnold Kriegstein and colleagues, deepening our understanding of the molecular and cellular dynamics of the developing human neocortex. The identification of a tripotential intermediate progenitor subtype is a key finding 🧪🧠🧬
www.nature.com/articles/s41...
Reposted by Erin Aboelnour, Ph.D.
news.ki.se/ms-brain-atl...
@annawilliamslab.bsky.social
@willmacnair.bsky.social
@deckardw.bsky.social
@karolinskainst.bsky.social
@edinburghuni.bsky.social
@cp-neuron.bsky.social
and many others....
@annawilliamslab.bsky.social
@willmacnair.bsky.social
@deckardw.bsky.social
@karolinskainst.bsky.social
@edinburghuni.bsky.social
@cp-neuron.bsky.social
and many others....
MS brain atlas could pave the way for personalised treatment
An international research team, including researchers at Karolinska Institutet, has mapped the genes expressed in the brain cells of people with multiple sclerosis (MS). The atlas, which is presented ...
news.ki.se
December 22, 2024 at 9:00 AM
Reposted by Erin Aboelnour, Ph.D.
Thrilled to see this paper out!! 🧪
Spatial transcriptomics of brain aging and 'spatial aging clocks' identify cells that have pro-aging or pro-rejuvenating effects on their neighbors!
Huge CONGRATS to Eric Sun and all authors! Fantastic collaboration with @jameszou.bsky.social!
rdcu.be/d33uQ 🧵
Spatial transcriptomics of brain aging and 'spatial aging clocks' identify cells that have pro-aging or pro-rejuvenating effects on their neighbors!
Huge CONGRATS to Eric Sun and all authors! Fantastic collaboration with @jameszou.bsky.social!
rdcu.be/d33uQ 🧵
Spatial transcriptomic clocks reveal cell proximity effects in brain ageing
Nature - A spatially resolved single-cell transcriptomics map of the mouse brain at different ages reveals signatures of ageing, rejuvenation and disease, including ageing effects associated with T...
rdcu.be
December 18, 2024 at 10:40 PM
Thrilled to see this paper out!! 🧪
Spatial transcriptomics of brain aging and 'spatial aging clocks' identify cells that have pro-aging or pro-rejuvenating effects on their neighbors!
Huge CONGRATS to Eric Sun and all authors! Fantastic collaboration with @jameszou.bsky.social!
rdcu.be/d33uQ 🧵
Spatial transcriptomics of brain aging and 'spatial aging clocks' identify cells that have pro-aging or pro-rejuvenating effects on their neighbors!
Huge CONGRATS to Eric Sun and all authors! Fantastic collaboration with @jameszou.bsky.social!
rdcu.be/d33uQ 🧵
Reposted by Erin Aboelnour, Ph.D.
3 reviews on planning, execution, & validation of transcriptomic experiments in neuroscience published in @natureportfolio.bsky.social #NatureNeuroscience.
A MUST READ if you're doing transcriptomics.
3 reviews, an amazing editorial, a beautiful cover – this is the issue of the year!
(mini thread)
A MUST READ if you're doing transcriptomics.
3 reviews, an amazing editorial, a beautiful cover – this is the issue of the year!
(mini thread)
December 11, 2024 at 5:04 PM
3 reviews on planning, execution, & validation of transcriptomic experiments in neuroscience published in @natureportfolio.bsky.social #NatureNeuroscience.
A MUST READ if you're doing transcriptomics.
3 reviews, an amazing editorial, a beautiful cover – this is the issue of the year!
(mini thread)
A MUST READ if you're doing transcriptomics.
3 reviews, an amazing editorial, a beautiful cover – this is the issue of the year!
(mini thread)
Reposted by Erin Aboelnour, Ph.D.
The December issue of Nature Neuroscience is now live, featuring our Focus on Single-Cell Genomics! We hope that these consensus reviews from experts in the field will serve as a useful guide for neuroscientists regarding best practices for these approaches.
www.nature.com/neuro/volume...
www.nature.com/neuro/volume...
Nature Neuroscience - Focus on single-cell genomics in neuroscience
Single-cell and single-nucleus genomics pave the way for a comprehensive understanding of the nervous system and its diverse cell populations. Realizing this...
www.nature.com
December 3, 2024 at 7:49 PM
The December issue of Nature Neuroscience is now live, featuring our Focus on Single-Cell Genomics! We hope that these consensus reviews from experts in the field will serve as a useful guide for neuroscientists regarding best practices for these approaches.
www.nature.com/neuro/volume...
www.nature.com/neuro/volume...
Reposted by Erin Aboelnour, Ph.D.
There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research.
A Place of Joy.
A Place of Joy.
December 3, 2024 at 2:00 PM
There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research.
A Place of Joy.
A Place of Joy.
Reposted by Erin Aboelnour, Ph.D.
Oligodendroglia starter pack!
Missing many, please share and comment below to be added. Go team Oligo 🧠🦋!
go.bsky.app/JgL2evN
Missing many, please share and comment below to be added. Go team Oligo 🧠🦋!
go.bsky.app/JgL2evN
November 17, 2024 at 8:59 PM
Oligodendroglia starter pack!
Missing many, please share and comment below to be added. Go team Oligo 🧠🦋!
go.bsky.app/JgL2evN
Missing many, please share and comment below to be added. Go team Oligo 🧠🦋!
go.bsky.app/JgL2evN
Reposted by Erin Aboelnour, Ph.D.
There’s still time to register for the first-time reviewers workshop with @reviewerzero.bsky.social!
Geared toward people in the 🧠 sciences but useful and open to all ✨
Register 👇🏽 blackinneuro47.wildapricot.org/event-5883989
#Neuroskyence #Blackademics #PhDSky #AcademicSky #BlackInSTEM 🧪
Geared toward people in the 🧠 sciences but useful and open to all ✨
Register 👇🏽 blackinneuro47.wildapricot.org/event-5883989
#Neuroskyence #Blackademics #PhDSky #AcademicSky #BlackInSTEM 🧪
December 2, 2024 at 10:50 PM
There’s still time to register for the first-time reviewers workshop with @reviewerzero.bsky.social!
Geared toward people in the 🧠 sciences but useful and open to all ✨
Register 👇🏽 blackinneuro47.wildapricot.org/event-5883989
#Neuroskyence #Blackademics #PhDSky #AcademicSky #BlackInSTEM 🧪
Geared toward people in the 🧠 sciences but useful and open to all ✨
Register 👇🏽 blackinneuro47.wildapricot.org/event-5883989
#Neuroskyence #Blackademics #PhDSky #AcademicSky #BlackInSTEM 🧪