Meng Wang
@drmengwang.bsky.social
Assistant Prof at Cornell University studying metabolism and DNA damage in cancer and aging. Alum of Cambridge and MRC-LMB. Dad!
Our lab road trip to #EMGS2025 at Rochester NY. Thank you to @emgsus.bsky.social for travel awards and poster presentations by postdoc Chris Mellor, grads Brandon James and Nick Cheng. A friendly and inviting community to bring trainees!
September 8, 2025 at 4:55 PM
Our lab road trip to #EMGS2025 at Rochester NY. Thank you to @emgsus.bsky.social for travel awards and poster presentations by postdoc Chris Mellor, grads Brandon James and Nick Cheng. A friendly and inviting community to bring trainees!
New publication from our lab! It was really fun writing this review @jcb.org with my postdoc Dr. Chris Mellor and graduate student Elisabeth Larson. We explore how folate deficiency trigger DNA damage that disrupt genome stability.
New review: Mellor, Larson, and @drmengwang.bsky.social discuss the molecular mechanisms of mammalian genomic instability arising from folate deficiency and how this impacts genome biology in health and disease. rupress.org/jcb/article/...
#CellMetabolism
#CellMetabolism
August 21, 2025 at 1:21 PM
New publication from our lab! It was really fun writing this review @jcb.org with my postdoc Dr. Chris Mellor and graduate student Elisabeth Larson. We explore how folate deficiency trigger DNA damage that disrupt genome stability.
Cornell NCAA 2025 D1 Champions! 13-10 Win over Maryland. What a game! @cornelluniversity.bsky.social @ncaa.bsky.social
May 26, 2025 at 7:35 PM
Cornell NCAA 2025 D1 Champions! 13-10 Win over Maryland. What a game! @cornelluniversity.bsky.social @ncaa.bsky.social
Many congratulations to Saeideh Azad, our talented Cornell undergraduate student who is graduating today @cornelluniversity.bsky.social. Saeideh has done a tremendous job working in our lab! We wish her all the best in her future endeavours!
May 23, 2025 at 2:23 PM
Many congratulations to Saeideh Azad, our talented Cornell undergraduate student who is graduating today @cornelluniversity.bsky.social. Saeideh has done a tremendous job working in our lab! We wish her all the best in her future endeavours!
Ok #AACR25, I’m truly impressed. A live sign-language interpreter translating Inigo’s @imartincorena.bsky.social plenary talk on somatic tissue mutational landscape. I want to learn the sign for ‘clonal’.
April 26, 2025 at 9:26 PM
Ok #AACR25, I’m truly impressed. A live sign-language interpreter translating Inigo’s @imartincorena.bsky.social plenary talk on somatic tissue mutational landscape. I want to learn the sign for ‘clonal’.
Exciting talk #AACR2025 @theaacr.bsky.social from my colleague and friend Dr. Karuna Ganesh! insights into why colon cancer is rising in young. A cool DNA damage mechanism! @karunamdphd.bsky.social @mskcancercenter.bsky.social
April 26, 2025 at 8:30 PM
Exciting talk #AACR2025 @theaacr.bsky.social from my colleague and friend Dr. Karuna Ganesh! insights into why colon cancer is rising in young. A cool DNA damage mechanism! @karunamdphd.bsky.social @mskcancercenter.bsky.social
Many congratulations to our newest PhD student Emma Kosmeder @cornelluniversity.bsky.social for achieving an Honorable Mention in this year’s #NationalScienceFoundation GRFP! Considering only 1000 GRFP awarded this yr versus >2000 awards in past yrs, I am so proud to be mentoring Emma in her PhD.
April 9, 2025 at 6:17 PM
Many congratulations to our newest PhD student Emma Kosmeder @cornelluniversity.bsky.social for achieving an Honorable Mention in this year’s #NationalScienceFoundation GRFP! Considering only 1000 GRFP awarded this yr versus >2000 awards in past yrs, I am so proud to be mentoring Emma in her PhD.
Absolute delight and privilege to host Dr. Anna Beaudin @beaudinlab.bsky.social from @utah.edu. Very exciting work on fetal folate🥑metabolism rewiring 🩸blood stem cells. Thank you for visiting Cornell and passing your wisdom to our trainees and assistant profs!
April 9, 2025 at 1:11 AM
Absolute delight and privilege to host Dr. Anna Beaudin @beaudinlab.bsky.social from @utah.edu. Very exciting work on fetal folate🥑metabolism rewiring 🩸blood stem cells. Thank you for visiting Cornell and passing your wisdom to our trainees and assistant profs!
Reposted by Meng Wang
Thrilled to share our latest work. Great collab with Costanzo, Masson, Freire and Reyes' labs. Congrats to María José and coauthors
HMCES corrupts replication fork stability during base excision repair in homologous recombination–deficient cells | Science Advances www.science.org/doi/10.1126/...
HMCES corrupts replication fork stability during base excision repair in homologous recombination–deficient cells | Science Advances www.science.org/doi/10.1126/...
HMCES corrupts replication fork stability during base excision repair in homologous recombination–deficient cells
HMCES binding to nascent DNA blocks replication and kills homologous recombination–deficient cancer cells.
www.science.org
March 27, 2025 at 10:29 PM
Thrilled to share our latest work. Great collab with Costanzo, Masson, Freire and Reyes' labs. Congrats to María José and coauthors
HMCES corrupts replication fork stability during base excision repair in homologous recombination–deficient cells | Science Advances www.science.org/doi/10.1126/...
HMCES corrupts replication fork stability during base excision repair in homologous recombination–deficient cells | Science Advances www.science.org/doi/10.1126/...
Reposted by Meng Wang
The maternal antibody paradox: how are these antibodies both good and bad? Excited to share our new insights for rotavirus vaccines
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Mechanisms of maternal antibody interference to rotavirus vaccination
Maternal antibodies (MatAbs) are transferred transplacentally during pregnancy and through breast milk after birth to provide protection whilst the neonatal immune response is immature. However, MatAb...
www.biorxiv.org
March 21, 2025 at 5:44 PM
The maternal antibody paradox: how are these antibodies both good and bad? Excited to share our new insights for rotavirus vaccines
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
During this chaotic time, I take satisfaction doing little things that improve the lab. Today I rigged an argon gas blower for our chemical hood. #labrat
February 24, 2025 at 9:45 PM
During this chaotic time, I take satisfaction doing little things that improve the lab. Today I rigged an argon gas blower for our chemical hood. #labrat
Reposted by Meng Wang
NIH indirects case update:
Hearing ongoing now, and I'll try to live tweet some notable exchanges.
Prior to more detailed arguments, Judge Kelley starts off with a few point questions to both sides:
(I'm paraphrasing here)
Hearing ongoing now, and I'll try to live tweet some notable exchanges.
Prior to more detailed arguments, Judge Kelley starts off with a few point questions to both sides:
(I'm paraphrasing here)
February 21, 2025 at 3:19 PM
NIH indirects case update:
Hearing ongoing now, and I'll try to live tweet some notable exchanges.
Prior to more detailed arguments, Judge Kelley starts off with a few point questions to both sides:
(I'm paraphrasing here)
Hearing ongoing now, and I'll try to live tweet some notable exchanges.
Prior to more detailed arguments, Judge Kelley starts off with a few point questions to both sides:
(I'm paraphrasing here)
Reposted by Meng Wang
It’s day 1 of the cut to NIH indirects and universities are scrambling to adapt. I’m going to post a series of videos on all the things I take for granted, but are both vital to research and covered by indirects for research grants.
February 10, 2025 at 4:49 PM
It’s day 1 of the cut to NIH indirects and universities are scrambling to adapt. I’m going to post a series of videos on all the things I take for granted, but are both vital to research and covered by indirects for research grants.
Reposted by Meng Wang
1. Today the NIH director issued a new directive slashing overhead rates to 15%.
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
grants.nih.gov
February 8, 2025 at 12:18 AM
1. Today the NIH director issued a new directive slashing overhead rates to 15%.
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
Reposted by Meng Wang
🚨RED ALERT for 🧪:
The Trump NIH just gashed indirect costs. This is a direct attack on universities.
“Pursuant to this Supplemental Guidance, there will be a standard rate of 15% across all NIH grants for indirect costs.” 😮
Just a devastating Friday night news dump. #scicomm #academicaky
The Trump NIH just gashed indirect costs. This is a direct attack on universities.
“Pursuant to this Supplemental Guidance, there will be a standard rate of 15% across all NIH grants for indirect costs.” 😮
Just a devastating Friday night news dump. #scicomm #academicaky
February 7, 2025 at 11:40 PM
🚨RED ALERT for 🧪:
The Trump NIH just gashed indirect costs. This is a direct attack on universities.
“Pursuant to this Supplemental Guidance, there will be a standard rate of 15% across all NIH grants for indirect costs.” 😮
Just a devastating Friday night news dump. #scicomm #academicaky
The Trump NIH just gashed indirect costs. This is a direct attack on universities.
“Pursuant to this Supplemental Guidance, there will be a standard rate of 15% across all NIH grants for indirect costs.” 😮
Just a devastating Friday night news dump. #scicomm #academicaky
Yes, doubleplusgood. Me writing my untruth grant in 2025.
February 4, 2025 at 5:50 PM
Yes, doubleplusgood. Me writing my untruth grant in 2025.
Merry Christmas and Happy New Year from the Wang Lab! I’m so thankful to my lab, discussing and doing science with you guys is the best part of the job!
December 20, 2024 at 11:58 AM
Merry Christmas and Happy New Year from the Wang Lab! I’m so thankful to my lab, discussing and doing science with you guys is the best part of the job!
Reposted by Meng Wang
The first paper from our lab is online! A wonderful collaboration with @scottbscience.bsky.social lab. We discover that Pol II is extensively regulated by Ubiquitin at the beginning of the transcription cycle!
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
CRL3ARMC5 ubiquitin ligase and Integrator phosphatase form parallel mechanisms to control early stages of RNA Pol II transcription
Cacioppo, Gillis, Shlamovitz, Zeller, et al. show that CRL3ARMC5 ubiquitylates RNA Pol II at early stages of transcription as part of a major homeostatic RNA Pol II turnover mechanism. CRL3ARMC5 and the Integrator phosphatase act as complementary pathways, monitoring the quantity and quality of RNA Pol II complexes before they are licensed into elongation.
www.cell.com
December 11, 2024 at 5:19 PM
The first paper from our lab is online! A wonderful collaboration with @scottbscience.bsky.social lab. We discover that Pol II is extensively regulated by Ubiquitin at the beginning of the transcription cycle!
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
Many congratulations to @rockefelleruniv.bsky.social MDPhD student and soon-to-be Dr Nicky Blobel from Smogorzewska Lab for passing his PhD defense today! It was my pleasure to be your external examiner and share our passion on endogenous DNA 🧬damage!
December 2, 2024 at 7:56 PM
Many congratulations to @rockefelleruniv.bsky.social MDPhD student and soon-to-be Dr Nicky Blobel from Smogorzewska Lab for passing his PhD defense today! It was my pleasure to be your external examiner and share our passion on endogenous DNA 🧬damage!
Can someone please rank my emotional stability compared to all undergraduates in their institution? I think my lab deserves to know.
November 28, 2024 at 4:28 PM
Can someone please rank my emotional stability compared to all undergraduates in their institution? I think my lab deserves to know.
Reposted by Meng Wang
🌟 Welcome to the MRC Laboratory of Molecular Biology on Bluesky!
We’re thrilled to connect with you and share our research insights, job opportunities, events, and more.
Join us on this journey as we advance science and improve human health together!
#MolecularBiology #Research #Innovation
We’re thrilled to connect with you and share our research insights, job opportunities, events, and more.
Join us on this journey as we advance science and improve human health together!
#MolecularBiology #Research #Innovation
November 22, 2024 at 10:05 AM
🌟 Welcome to the MRC Laboratory of Molecular Biology on Bluesky!
We’re thrilled to connect with you and share our research insights, job opportunities, events, and more.
Join us on this journey as we advance science and improve human health together!
#MolecularBiology #Research #Innovation
We’re thrilled to connect with you and share our research insights, job opportunities, events, and more.
Join us on this journey as we advance science and improve human health together!
#MolecularBiology #Research #Innovation