Andrew Wood
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drarwood.bsky.social
Andrew Wood
@drarwood.bsky.social
Statistical genetics, bioinformatics, data science. Originally comp. sci. Working on complex data. Army of 4. Guitars.
Reposted by Andrew Wood
Great to get together with the original genetics of complex traits team @exeter.ac.uk for the 30th birthday celebration of the genetics lab. We haven’t changed a bit! @rmfreathy.bsky.social @timfrayling.bsky.social @drarwood.bsky.social @mnweedon.bsky.social Hana Lange Allen & John Perry
September 14, 2025 at 2:57 PM
Reposted by Andrew Wood
In the latest update to the 23andMe, Anne Wojcicki (i.e., not REGN) won the bidding war.

www.wsj.com/tech/biotech...
Exclusive | Anne Wojcicki Wins Bidding for 23andMe
Regeneron is backing away from buying the DNA-testing company after a nonprofit controlled by co-founder Wojcicki made a higher bid.
www.wsj.com
June 13, 2025 at 9:15 PM
investor.regeneron.com
May 19, 2025 at 1:30 PM
Enjoyed contributing to the Broad's Medical and Population Genetics seminar series today and hearing some great talks. Thanks @joelhirschhorn.bsky.social for inviting me to speak.
April 10, 2025 at 8:02 PM
Reposted by Andrew Wood
Really excited to share our next population-scale WGS work preprint. Here, we analyse three anthropometric traits in nearly 700,000 individuals (discovery UKB ~450K, replication AoU). We show, for these traits, that common and rare variant heritability is convergent

www.biorxiv.org/content/10.1...
Whole-genome sequencing analysis of anthropometric traits in 672,976 individuals reveals convergence between rare and common genetic associations
Genetic association studies have mostly focussed on common variants from genotyping arrays or rare protein-coding variants from exome sequencing. Here, we used whole-genome sequence (WGS) data in 672,...
www.biorxiv.org
February 26, 2025 at 4:11 PM
Reposted by Andrew Wood
Excited to finally share that our paper looking at the effect of rare non-coding variants using WGS on circulating protein levels in the UKB has been released in Nature Genetics @naturegenet.bsky.social! We now analyse the full 3,000 circulating proteins in all 50,000 individuals rdcu.be/ea16i
Whole-genome sequencing analysis identifies rare, large-effect noncoding variants and regulatory regions associated with circulating protein levels
Nature Genetics - Rare variant association analysis of plasma proteins using whole-genome sequencing data in 54,306 individuals in the UK Biobank demonstrates that combining both single-variant and...
rdcu.be
February 24, 2025 at 6:26 PM
Excited to see our paper on medRxiv "Streamlining Large-Scale Genomic Data Management: Insights from the UK Biobank Whole-Genome Sequencing Data". Paper here:
www.medrxiv.org/content/10.1.... Tools here:
github.com/drarwood/vcf....
Streamlining Large-Scale Genomic Data Management: Insights from the UK Biobank Whole-Genome Sequencing Data
Biobank-scale Whole-Genome Sequencing (WGS) studies are increasingly pivotal in unraveling the genetic bases of diverse health outcomes. However, managing and analyzing these datasets' sheer volume an...
www.medrxiv.org
January 29, 2025 at 5:07 AM
I'd forgotten what a good song this is.
www.youtube.com/watch?v=fFhd...
Bruce Hornsby - The Way It Is (Radio 2 Piano Room)
YouTube video by BBC Music
www.youtube.com
January 14, 2025 at 7:31 PM
23andMe have just announced their TRE. See here 👀: investors.23andme.com/news-release...
investors.23andme.com
January 8, 2025 at 8:04 PM