David Martínez Millán
@dmartmillan.bsky.social
I am an engineer in a biological world.
Pinned
OpenVariant: a toolkit to parse and operate multiple input file formats
AbstractSummary. Advances in high-throughput DNA sequencing technologies and decreasing costs have fueled the identification of small genetic variants (suc
academic.oup.com
🎉 I'm thrilled to announce that OpenVariant is finally published! A comprehensive toolkit to facilitate reading, parsing and refinement of diverse input file formats in a customizable structure, all within a single process. @bbglab.bsky.social at @irbbarcelona.bsky.social
doi.org/10.1093/bioi...
doi.org/10.1093/bioi...
Reposted by David Martínez Millán
Very happy to share that our paper on the influence of biological sex and smoking in the clonal landscape of the normal human bladder is out today in Nature. Kudos to all the authors and especially to @ferriol.bsky.social for coming along with me during this project's journey!
🧵Summary following ⬇️
🧵Summary following ⬇️
🚨 New paper alert!
Sex and smoking bias in the selection of somatic mutations in human bladder
www.nature.com/articles/s41...
by @raquelbmi.bsky.social, @ferriol.bsky.social et al (in collaboration with Rosana Risques lab in @uwmedicine.bsky.social)
Sex and smoking bias in the selection of somatic mutations in human bladder
www.nature.com/articles/s41...
by @raquelbmi.bsky.social, @ferriol.bsky.social et al (in collaboration with Rosana Risques lab in @uwmedicine.bsky.social)
Sex and smoking bias in the selection of somatic mutations in human bladder - Nature
Sex bias and association with smoking history identified in the landscape of driver mutations and clonal expansions in normal human bladder tissue may explain the higher bladder cancer risk in men and smokers.
www.nature.com
October 8, 2025 at 5:10 PM
Very happy to share that our paper on the influence of biological sex and smoking in the clonal landscape of the normal human bladder is out today in Nature. Kudos to all the authors and especially to @ferriol.bsky.social for coming along with me during this project's journey!
🧵Summary following ⬇️
🧵Summary following ⬇️
Reposted by David Martínez Millán
🧪 Out in @nature.com: Smoking and biological sex shape healthy bladder tissue evolution, offering clues to #cancer risk.
✍️ #IRBBarcelona & University of Washington
➡️ bit.ly/42wcIN5
📌 DOI: 10.1038/s41586-025-09521-x
#IRBScience #CancerResearch #BladderCancer @bbglab.bsky.social
🧵👇
✍️ #IRBBarcelona & University of Washington
➡️ bit.ly/42wcIN5
📌 DOI: 10.1038/s41586-025-09521-x
#IRBScience #CancerResearch #BladderCancer @bbglab.bsky.social
🧵👇
October 8, 2025 at 3:01 PM
🧪 Out in @nature.com: Smoking and biological sex shape healthy bladder tissue evolution, offering clues to #cancer risk.
✍️ #IRBBarcelona & University of Washington
➡️ bit.ly/42wcIN5
📌 DOI: 10.1038/s41586-025-09521-x
#IRBScience #CancerResearch #BladderCancer @bbglab.bsky.social
🧵👇
✍️ #IRBBarcelona & University of Washington
➡️ bit.ly/42wcIN5
📌 DOI: 10.1038/s41586-025-09521-x
#IRBScience #CancerResearch #BladderCancer @bbglab.bsky.social
🧵👇
Reposted by David Martínez Millán
As we are quite new in that network, we take the chance to share our research achievements of the last year.
Here you can follow a short 🧵of our latest publications:
1️⃣
www.nature.com/articles/s41...
Here you can follow a short 🧵of our latest publications:
1️⃣
www.nature.com/articles/s41...
Five latent factors underlie response to immunotherapy - Nature Genetics
Analysis of human tumor datasets shows that all features that appear significantly associated with immunotherapy response and survival may be collapsed into five latent factors: tumor mutation burden, T cell effective infiltration, TGF-β activity in the microenvironment, prior treatment and tumor proliferative potential.
www.nature.com
January 21, 2025 at 3:51 PM
As we are quite new in that network, we take the chance to share our research achievements of the last year.
Here you can follow a short 🧵of our latest publications:
1️⃣
www.nature.com/articles/s41...
Here you can follow a short 🧵of our latest publications:
1️⃣
www.nature.com/articles/s41...
Reposted by David Martínez Millán
En memoria de Joan Guinovart, por Francesc Posas, Raúl Mendez y Margarida Corominas en nombre del @irbbarcelona.org del Que fue fundador.
DEP
elpais.com/espana/catal...
DEP
elpais.com/espana/catal...
Muere a los 77 años Joan Guinovart, fundador y exdirector del Institut de Recerca Biomèdica (IRB)
El científico y catedrático, Creu de Sant Jordi en 2014, fue una figura clave en el ámbito de la bioquímica
elpais.com
January 2, 2025 at 3:22 PM
En memoria de Joan Guinovart, por Francesc Posas, Raúl Mendez y Margarida Corominas en nombre del @irbbarcelona.org del Que fue fundador.
DEP
elpais.com/espana/catal...
DEP
elpais.com/espana/catal...
Reposted by David Martínez Millán
OpenVariant: a toolkit to parse and operate multiple input file formats https://academic.oup.com/bioinformatics/advance-article/doi/10.1093/bioinformatics/btae714/7914924 🧬🖥️🧪 https://github.com/bbglab/openvariant
December 3, 2024 at 9:00 PM
OpenVariant: a toolkit to parse and operate multiple input file formats https://academic.oup.com/bioinformatics/advance-article/doi/10.1093/bioinformatics/btae714/7914924 🧬🖥️🧪 https://github.com/bbglab/openvariant
Reposted by David Martínez Millán
OpenVariant: a toolkit to parse and operate multiple input file formats. #Genomics #VariantFormats #InputFileFormats #Bioinformatics 🧬 🖥️
Github; github.com/bbglab/openv...
academic.oup.com/bioinformati...
Github; github.com/bbglab/openv...
academic.oup.com/bioinformati...
OpenVariant: a toolkit to parse and operate multiple input file formats
AbstractSummary. Advances in high-throughput DNA sequencing technologies and decreasing costs have fueled the identification of small genetic variants (suc
academic.oup.com
December 4, 2024 at 10:49 PM
OpenVariant: a toolkit to parse and operate multiple input file formats. #Genomics #VariantFormats #InputFileFormats #Bioinformatics 🧬 🖥️
Github; github.com/bbglab/openv...
academic.oup.com/bioinformati...
Github; github.com/bbglab/openv...
academic.oup.com/bioinformati...
🎉 I'm thrilled to announce that OpenVariant is finally published! A comprehensive toolkit to facilitate reading, parsing and refinement of diverse input file formats in a customizable structure, all within a single process. @bbglab.bsky.social at @irbbarcelona.bsky.social
doi.org/10.1093/bioi...
doi.org/10.1093/bioi...
OpenVariant: a toolkit to parse and operate multiple input file formats
AbstractSummary. Advances in high-throughput DNA sequencing technologies and decreasing costs have fueled the identification of small genetic variants (suc
academic.oup.com
December 12, 2024 at 10:11 AM
🎉 I'm thrilled to announce that OpenVariant is finally published! A comprehensive toolkit to facilitate reading, parsing and refinement of diverse input file formats in a customizable structure, all within a single process. @bbglab.bsky.social at @irbbarcelona.bsky.social
doi.org/10.1093/bioi...
doi.org/10.1093/bioi...