Dima Rinberg
@dimarinberg.bsky.social
Neuroscientist at the NYU School of Medicine. Study the sense of smell.
Reposted by Dima Rinberg
🚨 Preprint alert! 🚨
Can mice estimate the distance to an odour source?
New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself.
Spoiler alert: Yes, they can!
Read the paper here: bit.ly/43A9tF9
Short 🧵 below
Can mice estimate the distance to an odour source?
New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself.
Spoiler alert: Yes, they can!
Read the paper here: bit.ly/43A9tF9
Short 🧵 below
May 18, 2025 at 8:41 AM
🚨 Preprint alert! 🚨
Can mice estimate the distance to an odour source?
New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself.
Spoiler alert: Yes, they can!
Read the paper here: bit.ly/43A9tF9
Short 🧵 below
Can mice estimate the distance to an odour source?
New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself.
Spoiler alert: Yes, they can!
Read the paper here: bit.ly/43A9tF9
Short 🧵 below
Reposted by Dima Rinberg
Linking function and structure at scale with X-rays - and several times over. Massive congratulations to the team @yuxinzhang.bsky.social, @carlesbosch.bsky.social, @apacureanu.bsky.social @esrf.fr, @crick.ac.uk and all our collaborators.
My PhD project is out as a preprint!
We combined 2P and synchrotron X-ray to understand mouse olfactory bulb circuits, linking physiology to structure in 3 animals!
doi.org/10.1101/2025...
🙌 @carlesbosch.bsky.social, @apacureanu.bsky.social, @andreas-t-schaefer.bsky.social, @esrf.fr, @crick.ac.uk
We combined 2P and synchrotron X-ray to understand mouse olfactory bulb circuits, linking physiology to structure in 3 animals!
doi.org/10.1101/2025...
🙌 @carlesbosch.bsky.social, @apacureanu.bsky.social, @andreas-t-schaefer.bsky.social, @esrf.fr, @crick.ac.uk
May 1, 2025 at 12:24 PM
Linking function and structure at scale with X-rays - and several times over. Massive congratulations to the team @yuxinzhang.bsky.social, @carlesbosch.bsky.social, @apacureanu.bsky.social @esrf.fr, @crick.ac.uk and all our collaborators.
Reposted by Dima Rinberg
Due to a coincidence of timing, several PIs at NIMH had a term appointment that ended in Feb.
But renewals were blocked.
Several members of the NIMH external review board, led by chair @jmgrohneuro.bsky.social, wrote a letter to the Senate. It's worth a read.
2/
But renewals were blocked.
Several members of the NIMH external review board, led by chair @jmgrohneuro.bsky.social, wrote a letter to the Senate. It's worth a read.
2/
March 10, 2025 at 3:59 AM
Due to a coincidence of timing, several PIs at NIMH had a term appointment that ended in Feb.
But renewals were blocked.
Several members of the NIMH external review board, led by chair @jmgrohneuro.bsky.social, wrote a letter to the Senate. It's worth a read.
2/
But renewals were blocked.
Several members of the NIMH external review board, led by chair @jmgrohneuro.bsky.social, wrote a letter to the Senate. It's worth a read.
2/
Reposted by Dima Rinberg
New preprint: a simple method (ADePT) for optical control and recording of activity by axially-decoupling the focal planes for widefield patterned photo-stimulation and two photon imaging. Proof-of-principle analysis of functional connectivity in the olfactory bulb. 1/7 #neuroscience
Axially decoupled photo-stimulation and two photon readout (ADePT) for mapping functional connectivity of neural circuits
All optical physiology in vivo provides a conduit for investigating the function of neural circuits in 3-D. Here, we report a new strategy for flexible, axially-decoupled photo-stimulation and two pho...
doi.org
February 26, 2025 at 5:02 PM
New preprint: a simple method (ADePT) for optical control and recording of activity by axially-decoupling the focal planes for widefield patterned photo-stimulation and two photon imaging. Proof-of-principle analysis of functional connectivity in the olfactory bulb. 1/7 #neuroscience
Reposted by Dima Rinberg
Here it is finally: Our mathematical methods book for life scientists! Aimed at advanced undergrads and beginning grad students, plus all those who want a deeper look at the math behind quantitative biology. @portugueslab.bsky.social.
1/3
1/3
"Mathematics in Biology" is a concise but rigorous textbook for advanced undergraduate and graduate students across the biological sciences that provides a foundation for understanding the methods used in quantitative biology: @mameister4.bsky.social
Mathematics in Biology
Biology has turned into a quantitative science. The core problems in the life sciences today involve complex systems that require mathematical expression, ye...
mitpress.mit.edu
February 20, 2025 at 6:32 PM
Here it is finally: Our mathematical methods book for life scientists! Aimed at advanced undergrads and beginning grad students, plus all those who want a deeper look at the math behind quantitative biology. @portugueslab.bsky.social.
1/3
1/3
Reposted by Dima Rinberg
Yes, many worrying things happening in science that should take priority in grabbing our attention - but we are worried precisely because scientific knowledge is worth creating. In that spirit, I am proud to highlight our latest @biorxivpreprint.bsky.social preprint! #neuroscience 🧪
Perception and neural representation of intermittent odor stimuli in mice
Odor cues in nature are sparse and highly fluctuating due to turbulent transport. To investigate how animals perceive these intermittent cues, we developed a behavioral task in which head-restrained m...
www.biorxiv.org
February 13, 2025 at 6:34 PM
Yes, many worrying things happening in science that should take priority in grabbing our attention - but we are worried precisely because scientific knowledge is worth creating. In that spirit, I am proud to highlight our latest @biorxivpreprint.bsky.social preprint! #neuroscience 🧪
Reposted by Dima Rinberg
From logical gates to grandmother cells, neuroscientists have employed many metaphors to explain single neuron function. Dmitri Chklovskii makes the case that neurons are actually trying to control how their outputs affect the rest of the brain.
By Paul Middlebrooks
bit.ly/4hPYk7w
#neuroskyence
By Paul Middlebrooks
bit.ly/4hPYk7w
#neuroskyence
Dmitri Chklovskii outlines how single neurons may act as their own optimal feedback controllers
From logical gates to grandmother cells, neuroscientists have employed many metaphors to explain single neuron function. Chklovskii makes the case that neurons are actually trying to control how their...
www.thetransmitter.org
February 12, 2025 at 3:53 PM
From logical gates to grandmother cells, neuroscientists have employed many metaphors to explain single neuron function. Dmitri Chklovskii makes the case that neurons are actually trying to control how their outputs affect the rest of the brain.
By Paul Middlebrooks
bit.ly/4hPYk7w
#neuroskyence
By Paul Middlebrooks
bit.ly/4hPYk7w
#neuroskyence
Reposted by Dima Rinberg
New paper from the lab: feedback from piriform cortex to the olfactory bulb carries identity and reward contingency signals in a multimodal (odor and sound) rule-reversal task. Feedback is re-formatted within seconds and reflects changes in the perceived rules of engagement.
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Fast updating feedback from piriform cortex to the olfactory bulb relays multimodal identity and reward contingency signals during rule-reversal - Nature Communications
Hernandez-Trejo, Ciuparu, and Garcia da Silva et al. report that the piriform-to-olfactory bulb feedback in the mouse carries multimodal identity and reward contingency signals, which are re-formatted...
doi.org
January 23, 2025 at 11:27 AM
New paper from the lab: feedback from piriform cortex to the olfactory bulb carries identity and reward contingency signals in a multimodal (odor and sound) rule-reversal task. Feedback is re-formatted within seconds and reflects changes in the perceived rules of engagement.
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Reposted by Dima Rinberg
Our perspective on designing electronic noses inspired by natural olfaction! #neuroscience #ChemSky 🧪
Design Principles From Natural Olfaction for Electronic Noses
Unlocking “universal smell” requires integrating key principles of natural olfactory systems: modulation of gas transport, utilization of non-selective sensing elements, chemical filters akin to the ...
advanced.onlinelibrary.wiley.com
January 21, 2025 at 2:17 PM
Our perspective on designing electronic noses inspired by natural olfaction! #neuroscience #ChemSky 🧪
Reposted by Dima Rinberg
my talk about deep learning in olfaction at NAISys 2024 is posted on yoitube: www.youtube.com/watch?v=RRo5...
My talk at NAISys 2024 conference at CSHL.
YouTube video by Alexei Koulakov
www.youtube.com
December 28, 2024 at 4:22 PM
my talk about deep learning in olfaction at NAISys 2024 is posted on yoitube: www.youtube.com/watch?v=RRo5...
Reposted by Dima Rinberg
Our DeepNose paper is in arxiv. In it, we present an equivariant CNN which can predict human olfactory perception based on molecular shapes, including mixtures. Comments/suggestions are very welcome.
arxiv.org/abs/2412.08747
arxiv.org/abs/2412.08747
DeepNose: An Equivariant Convolutional Neural Network Predictive Of Human Olfactory Percepts
The olfactory system employs responses of an ensemble of odorant receptors (ORs) to sense molecules and to generate olfactory percepts. Here we hypothesized that ORs can be viewed as 3D spatial filter...
arxiv.org
December 13, 2024 at 5:20 PM
Our DeepNose paper is in arxiv. In it, we present an equivariant CNN which can predict human olfactory perception based on molecular shapes, including mixtures. Comments/suggestions are very welcome.
arxiv.org/abs/2412.08747
arxiv.org/abs/2412.08747
Reposted by Dima Rinberg
Glad to share this theory paper on learning to align neural representations with sparse connectivity. Work led by graduate student @leo-bo-liu.bsky.social, in a wonderful collaboration with Yuhai Tu from IBM Research and @shanq.bsky.social from Flatiron Institute. #neuroscience 🧪
One nose but two nostrils: Learning to align with sparse connections between two olfactory cortices
Sparse connectivity between brain hemispheres is sufficient to learn and achieve bilateral alignment based on a realistic local learning rule.
journals.aps.org
December 2, 2024 at 7:00 PM
Glad to share this theory paper on learning to align neural representations with sparse connectivity. Work led by graduate student @leo-bo-liu.bsky.social, in a wonderful collaboration with Yuhai Tu from IBM Research and @shanq.bsky.social from Flatiron Institute. #neuroscience 🧪