Dominic Gonschorek
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dgonschorek.bsky.social
Dominic Gonschorek
@dgonschorek.bsky.social
170 followers 160 following 3 posts
Postdoc @EulerLab interested in visual neuroscience and machine learning.
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Reposted by Dominic Gonschorek
unituebingen.bsky.social
Eine neue Software ermöglicht Gehirnsimulationen, die sowohl detailliert die Prozesse im Gehirn imitieren als auch anspruchsvolle kognitive Aufgaben lösen können. Entwickelt wurde das Programm von einem Forschungsteam am Exzellenzcluster @ ml4science.bsky.social der Universität Tübingen.
November 14, 2025 at 8:21 AM
Reposted by Dominic Gonschorek
plosbiology.org
The state of our brain shapes what we see. @dgonschorek.bsky.social & @teuler.bsky.social explore a @plosbiology.org study showing that #brain state-dependent release of #histamine modulates the very first stage of #vision – the #retina 🧪 Paper: plos.io/49K0Qv8 Primer: plos.io/3LupFkL
Histamine modulates early visual processing in awake mice. Top left: Visual responses were recorded in awake, head-fixed mice using single-unit extracellular recordings from retinal ganglion cell (RGC) axons in the optic tract and from dorsal lateral geniculate nucleus (dLGN) neurons, while pupil dynamics and locomotion were monitored. Top right: Tripodi and Asari manipulated histaminergic input to the retina by chemogenetic activation of hypothalamic tuberomammillary nucleus (TMN) neurons or by systemic pharmacology targeting histamine receptors. H3 receptor antagonists increase histamine release, whereas H1 receptor antagonists block postsynaptic histamine effects. Bottom left: Increasing histamine levels, either chemogenetically or pharmacologically, slowed and weakened visual responses in both RGC axons and dLGN neurons, whereas blocking H1 receptors had the opposite effect, consistent with H1 receptor-mediated gain modulation. Bottom right: Ethological implication: in nocturnal mice, histamine levels are low during daytime, when the animals rest, enabling faster and stronger retinal responses and potentially facilitating rapid detection of threats. At nighttime, when the animals are active, high histamine levels suppress and slow visual responses. Partly created with biorender.com.
November 7, 2025 at 1:44 PM
Reposted by Dominic Gonschorek
mpi-animalbehav.bsky.social
Scientists discover the secret behind the shrew’s amazing ability to shrink their brains 🧠

The clever trick sheds unwanted weight without compromising too much on cognition.

Find the 5-letter word 👇

Study by @cecibaldoni.bsky.social Dechmann Lab #shrewcrew et al

www.ab.mpg.de/743885/news_...
Rare seasonal brain shrinkage in shrews is driven by water loss, not cell death
Common shrews are one of only a handful of mammals known to flexibly shrink and regrow their brains. This rare seasonal cycle, known as Dehnel’s phenomenon, has puzzled scientists for decades. A study...
www.ab.mpg.de
September 1, 2025 at 8:41 PM
Reposted by Dominic Gonschorek
snstuebingen.bsky.social
🔵Tübingen SNS 2025🔵

Registration is still open for the #SNS2025 event on 6-7 October!

Join us for plenary lectures 🗣️, poster sessions📊and social events 👥 about system neuroscience!🧠

Registration at meg.medizin.uni-tuebingen.de/sns_2025
August 29, 2025 at 7:53 AM
Reposted by Dominic Gonschorek
neurovenki.bsky.social
Thrilled to share this work, long time in the making! Carried through creatively by @siddjakes.bsky.social after initial design & piloting by @trackingskills.bsky.social, with help from @trackingactions.bsky.social. Modeling in collaboration with Massimo Vergassola & Nicola Rigolli.
Mice navigate scent trails using predictive policies
Animals actively sense their environment to extract features of interest to guide behaviors. For mammals, odors are prominent environmental features which are sampled by active modulation of sniffing ...
www.biorxiv.org
September 1, 2025 at 7:06 PM
Reposted by Dominic Gonschorek
eye-tuebingen.bsky.social
Strengthening European Ties: Institut de la Vision in Paris visits the IOR in Tübingen. This meeting was the first of its kind between the 2 internationally renowned institutes in vision and ophthalmology.
@unituebingen.bsky.social @tueneurocampus.bsky.social

www.eye-tuebingen.de?tx_news_pi1%...
Strengthening European Ties: Institut de la Vision in Paris visits the Institute of Ophthalmic Research in Tübingen
This meeting marked the first of its kind between the two institutions.
www.eye-tuebingen.de
April 4, 2025 at 9:25 AM
dgonschorek.bsky.social
If you submitted a paper to #ICML2025 and want to know how well your score compares overall, here is a good resource to keep track of your chances of getting it accepted this year. Fingers crossed for everyone!
papercopilot.com/statistics/i...
ICML 2025 Statistics - Paper Copilot
papercopilot.com
March 25, 2025 at 1:02 PM
Reposted by Dominic Gonschorek
nerflabs.bsky.social
Thus new review by Jennifer Hoy (University of Nevada) and Karl Farrow (NERF) takes a deep dive into the role of the superior colliculus.
https://www.cell.com/current-biology/fulltext/S0960-9822(25)00052-1

Beautifully illustrated by Pia Rachedi + open access

@farrowlab.bsky.social
March 18, 2025 at 6:48 AM
Reposted by Dominic Gonschorek
fededagos.bsky.social
🚨 New paper alert! 🚨
We’ve just launched openretina, an open-source framework for collaborative retina modeling across datasets and species.
A 🧵👇 (1/9)
March 14, 2025 at 9:41 AM
Reposted by Dominic Gonschorek
pessoabrain.bsky.social
𝗡𝗲𝗰𝗲𝘀𝘀𝗶𝘁𝘆 𝗮𝗻𝗱 𝗦𝘂𝗳𝗳𝗶𝗰𝗶𝗲𝗻𝗰𝘆 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻
Excellent short piece about causation in the brain by @neurograce.bsky.social
In a complex system talking about necessary and sufficient is not productive.

www.thetransmitter.org/systems-neur...
Claims of necessity, sufficiency don’t work well for studies of complex systems
Early studies on necessary and sufficient neural populations were done on simple invertebrate circuits. Does this logic work for complex outputs?
www.thetransmitter.org
February 9, 2025 at 4:48 PM
Reposted by Dominic Gonschorek
neurofishh.bsky.social
Seeking input: A standardized nomenclature
for the rods and cones of the vertebrate retina

A number of us have been working on a proposal to bring various disconnected naming systems for the vertebrate rods and cones across species into alignment. The basic proposal looks like this:
February 5, 2025 at 3:34 PM
Reposted by Dominic Gonschorek
eye-tuebingen.bsky.social
The results in a publication of an important scientific collaboration between IOR in Tübingen and the IdV in Paris! With the first detailed analysis of the modulatory effects of nitric oxide on retinal ganglion cells.
@unituebingen.bsky.social @tueneurocampus.bsky.social

👉 doi.org/10.7554/eLif...
Nitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells
Nitric oxide is a type-selective neuromodulator affecting the temporal, but not the spatial response kinetics of a specific subset of mouse retinal ganglion cells.
doi.org
January 21, 2025 at 6:19 PM
Reposted by Dominic Gonschorek
mordecwhy.bsky.social
I've added a new summary to the top of the Kickstarter, thanks to the advice of the excellent @matthewkressel.net. I think what I'm seeing right now is that I may need to clarify the importance of what's been happening in neuroscience. Refining the message!

www.kickstarter.com/projects/454...
AI: How We Got Here—A Neuroscience Perspective
A deep dive into the research of neuroscientists, who have uncovered a stunning way of interpreting AI progress
www.kickstarter.com
January 20, 2025 at 7:38 PM
Reposted by Dominic Gonschorek
teuler.bsky.social
Our paper on how the neuromodulator nitric oxide modulates a subset of mouse retinal ganglion cells is finally published in @elife.bsky.social doi.org/10.7554/eLif... Great work by @dgonschorek.bsky.social together with the lab of @oliviermarre.bsky.social and @matigoldin.bsky.social, ...
January 10, 2025 at 3:16 PM