Daniel Diaz
@dddiaz.com
Bioinformatics Engineer🧑💻@ Illumina (Illumina Dragen 🐉).
I am interested in anything Genomics 🧬, Space 🚀, or Type 1 Diabetes 💉🤖 related! #T1D Thoughts my own.
🏠: dddiaz.com
I am interested in anything Genomics 🧬, Space 🚀, or Type 1 Diabetes 💉🤖 related! #T1D Thoughts my own.
🏠: dddiaz.com
Pinned
Daniel Diaz
@dddiaz.com
· Feb 7
Exploring my own genome. | Daniel Diaz's Website
Using Dragen to explore my auto-immune variants, and explore the question of WHY someone gets diabetes.
dddiaz.com
#HiSciSky 👋
I am a Bioinformatics Engineer working on Product Development for Illumina. I am interested in anything genomics 🧬 , diabetes 💉, or space 🚀related!
I recently wrote about exploring my own diabetes genomic variants here: dddiaz.com/post/hla/
I am a Bioinformatics Engineer working on Product Development for Illumina. I am interested in anything genomics 🧬 , diabetes 💉, or space 🚀related!
I recently wrote about exploring my own diabetes genomic variants here: dddiaz.com/post/hla/
Erin did an amazing job capturing "my why".
www.illumina.com/company/news...
#genomics #illumina #DRAGEN
www.illumina.com/company/news...
#genomics #illumina #DRAGEN
How an Illumina bioinformatics engineer contributes to the company mission
For Daniel Diaz, it’s not just a job: He’s motivated by the belief that one day we’ll have a better understanding of all diseases
www.illumina.com
September 15, 2025 at 10:23 PM
Erin did an amazing job capturing "my why".
www.illumina.com/company/news...
#genomics #illumina #DRAGEN
www.illumina.com/company/news...
#genomics #illumina #DRAGEN
Genetically modified Beta Cells that are immune evasive. This is an incredible step in the right direction to a possible #Type1Diabetes cure that does not require immune suppression.
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
Survival of Transplanted Allogeneic Beta Cells with No Immunosuppression | NEJM
The need to suppress a patient’s immune system after the transplantation of allogeneic
cells is associated with wide-ranging side effects. We report the outcomes of transplantation
of genetically m...
www.nejm.org
August 5, 2025 at 4:50 AM
Genetically modified Beta Cells that are immune evasive. This is an incredible step in the right direction to a possible #Type1Diabetes cure that does not require immune suppression.
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
Reposted by Daniel Diaz
"I sit here and get to do one of the coolest jobs in the world & play baseball for a living, and I do all that as type 1 diabetic. I hope to be an inspiration to kids that they can do anything they want to."
#Padres pitcher Mason Miller on living with type one diabetes
youtu.be/3Hg5Cu4s9FQ?...
#Padres pitcher Mason Miller on living with type one diabetes
youtu.be/3Hg5Cu4s9FQ?...
Padres pitcher Mason Miller on living with Type 1 diabetes &who he is away from the baseball field
YouTube video by Marty Caswell MartyTimeTV
youtu.be
August 3, 2025 at 6:24 PM
"I sit here and get to do one of the coolest jobs in the world & play baseball for a living, and I do all that as type 1 diabetic. I hope to be an inspiration to kids that they can do anything they want to."
#Padres pitcher Mason Miller on living with type one diabetes
youtu.be/3Hg5Cu4s9FQ?...
#Padres pitcher Mason Miller on living with type one diabetes
youtu.be/3Hg5Cu4s9FQ?...
This is Epic! 🚀 Axiom Mission 4 will research the accuracy of continuous glucose monitors #CGM and the viability of different insulins in space! With the end goal to "eventually fly a crew member with the condition". #T1D #diabetes
issnationallab.org/press-releas...
issnationallab.org/press-releas...
New Space-Based Research May Pave the Way for First Astronaut with Diabetes
The Axiom Mission 4 crew will launch to the ISS with an investigation to advance diabetes management on Earth and in space.
issnationallab.org
June 3, 2025 at 8:47 PM
This is Epic! 🚀 Axiom Mission 4 will research the accuracy of continuous glucose monitors #CGM and the viability of different insulins in space! With the end goal to "eventually fly a crew member with the condition". #T1D #diabetes
issnationallab.org/press-releas...
issnationallab.org/press-releas...
A parent with #T1D gives the child a sub-5 % early-life risk, but a parent who carries a T1D genetic burden in the top 1% can push the child’s risk higher (even if that parent does not have #T1D!) So in some cases PGS > Family History of T1D (excluding if both parents have T1D)
#Diabetes #Genomics
#Diabetes #Genomics
Effects of parental autoimmune diseases on type 1 diabetes in offspring can be partially explained by HLA and non-HLA polymorphisms
www.cell.com/cell-genomic...
@andganna.bsky.social
www.cell.com/cell-genomic...
@andganna.bsky.social
April 25, 2025 at 8:20 PM
I think i just heard the sonic boom from the spacex landing in oceanside! Wish I knew about it earlier so I could have watched it.
April 4, 2025 at 4:42 PM
I think i just heard the sonic boom from the spacex landing in oceanside! Wish I knew about it earlier so I could have watched it.
Just finished reading #Abundance by Ezra Klein and
@dkthomp.bsky.social . Well worth it! The authors sum up the book well in the first chapter: "This book is dedicated to a simple idea: to have the future we want, we need to build and invent more of what we need." #booksky
@dkthomp.bsky.social . Well worth it! The authors sum up the book well in the first chapter: "This book is dedicated to a simple idea: to have the future we want, we need to build and invent more of what we need." #booksky
April 1, 2025 at 8:37 PM
Just finished reading #Abundance by Ezra Klein and
@dkthomp.bsky.social . Well worth it! The authors sum up the book well in the first chapter: "This book is dedicated to a simple idea: to have the future we want, we need to build and invent more of what we need." #booksky
@dkthomp.bsky.social . Well worth it! The authors sum up the book well in the first chapter: "This book is dedicated to a simple idea: to have the future we want, we need to build and invent more of what we need." #booksky
4 life changing technologies I use made possible by #NIH Research and the "Special Diabetes Program":
- #Tandem Control IQ (Insulin delivery algorithm)
- #Omnipod 5 (Insulin Pump)
- #Dexcom G6 (Continuous Glucose Monitor)
- Glucagon gvoke (Life saving low blood sugar treatment)
#T1D
- #Tandem Control IQ (Insulin delivery algorithm)
- #Omnipod 5 (Insulin Pump)
- #Dexcom G6 (Continuous Glucose Monitor)
- Glucagon gvoke (Life saving low blood sugar treatment)
#T1D
March 2, 2025 at 7:59 PM
Was pleasantly surprised when I opened LinkedIn to find out #Illumina had quoted me on their page! Pretty cool! 🧬💻🙂 : www.linkedin.com/posts/illumi...
Illumina on LinkedIn: Illumina: Culture | LinkedIn
We asked our employees what they envision for the future of genomics – here's what they had to say. 🧬
www.linkedin.com
February 26, 2025 at 5:58 AM
Was pleasantly surprised when I opened LinkedIn to find out #Illumina had quoted me on their page! Pretty cool! 🧬💻🙂 : www.linkedin.com/posts/illumi...
Illumina's Innovation Roadmap: 👀 www.illumina.com/science/geno...
- Constellation mapped reads (sequencing with no library prep!)
- Spatial transcriptomics
- 5-base solution for methylation
- Multiomic data analysis
Pretty exciting if you ask me, but I am biased 😂
#illumina #AGBT25
- Constellation mapped reads (sequencing with no library prep!)
- Spatial transcriptomics
- 5-base solution for methylation
- Multiomic data analysis
Pretty exciting if you ask me, but I am biased 😂
#illumina #AGBT25
Illumina Innovation Roadmap
Learn about upcoming technologies being developed into future products as part of our continuous innovation.
www.illumina.com
February 25, 2025 at 3:25 AM
Illumina's Innovation Roadmap: 👀 www.illumina.com/science/geno...
- Constellation mapped reads (sequencing with no library prep!)
- Spatial transcriptomics
- 5-base solution for methylation
- Multiomic data analysis
Pretty exciting if you ask me, but I am biased 😂
#illumina #AGBT25
- Constellation mapped reads (sequencing with no library prep!)
- Spatial transcriptomics
- 5-base solution for methylation
- Multiomic data analysis
Pretty exciting if you ask me, but I am biased 😂
#illumina #AGBT25
This is what a world with personalized medicine can look like: Vaccines that are trained to target your specific cancer cells. Super interesting!
www.nature.com/articles/s41...
#genomics #cancer
www.nature.com/articles/s41...
#genomics #cancer
A neoantigen vaccine generates antitumour immunity in renal cell carcinoma - Nature
A phase I trial of a neoantigen-targeting personalized cancer vaccine led to durable and polyfunctional T cell responses and antitumour recognition, and was associated with no recurrence in patie...
www.nature.com
February 6, 2025 at 11:23 PM
This is what a world with personalized medicine can look like: Vaccines that are trained to target your specific cancer cells. Super interesting!
www.nature.com/articles/s41...
#genomics #cancer
www.nature.com/articles/s41...
#genomics #cancer
Oh wow, it’s been so long since I have “binged” a book! I picked up Project Hail Mary at the beginning of the week and I just finished it!So good, not a single dull moment! #booksky
January 25, 2025 at 2:45 AM
Oh wow, it’s been so long since I have “binged” a book! I picked up Project Hail Mary at the beginning of the week and I just finished it!So good, not a single dull moment! #booksky
This reflects my experience with a GLP-1 as a #T1D as well. Onboarding was rough, but it made my management a lot easier. #t1d #diabetes
Combining GLP-1 and insulin for Type 1 diabetes: a small randomized trial showed reduced insulin need, less carbohydrate intake, better glucose regulation, and reduced body weight
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Subcutaneous weekly semaglutide with automated insulin delivery in type 1 diabetes: a double-blind, randomized, crossover trial - Nature Medicine
In a crossover trial evaluating semaglutide versus placebo as an add-on to automated insulin delivery therapy in adults with type 1 diabetes, the use of semaglutide was associated with an increased pe...
www.nature.com
January 10, 2025 at 6:12 PM
Very exciting development for immune evasive islet cells. These were transplanted, which are not readily available, but the hope is this could be extended into stem cell derived islets. www.breakthrought1d.org/news-and-upd...
#t1d #diabetes #stemcells
#t1d #diabetes #stemcells
Cell therapy first: transplanted islets working without immunosuppressives - Breakthrough T1D
The recipient of gene-edited islets to evade the immune system is making insulin without the use of immunusuppresives.
www.breakthrought1d.org
January 7, 2025 at 9:47 PM
Very exciting development for immune evasive islet cells. These were transplanted, which are not readily available, but the hope is this could be extended into stem cell derived islets. www.breakthrought1d.org/news-and-upd...
#t1d #diabetes #stemcells
#t1d #diabetes #stemcells
5 lessons I learned in 2024:
1. The value of emotional intelligence
2. We do things because they are hard
3. The Internet is not a valid "third place"
4. Diabetes research is still advancing rapidly
5. Eclipses are cool.
You can see the full post here:
www.dddiaz.com/post/learned...
#yearinreview
1. The value of emotional intelligence
2. We do things because they are hard
3. The Internet is not a valid "third place"
4. Diabetes research is still advancing rapidly
5. Eclipses are cool.
You can see the full post here:
www.dddiaz.com/post/learned...
#yearinreview
5 Things I Learned in 2024 | Daniel Diaz's Website
5 Things I Learned in 2024
www.dddiaz.com
January 2, 2025 at 6:42 PM
5 lessons I learned in 2024:
1. The value of emotional intelligence
2. We do things because they are hard
3. The Internet is not a valid "third place"
4. Diabetes research is still advancing rapidly
5. Eclipses are cool.
You can see the full post here:
www.dddiaz.com/post/learned...
#yearinreview
1. The value of emotional intelligence
2. We do things because they are hard
3. The Internet is not a valid "third place"
4. Diabetes research is still advancing rapidly
5. Eclipses are cool.
You can see the full post here:
www.dddiaz.com/post/learned...
#yearinreview
Interesting new paper using Dexcom cgm data and an ml model to identify 4 different sub phenotypes for type 2 diabetes.
- Muscle insulin resistance
- Hepatic insulin resistance
- β-cell dysfunction
- Impaired incretin action
#diabetes #dexcom #cgm #t2d
www.nature.com/articles/s41...
- Muscle insulin resistance
- Hepatic insulin resistance
- β-cell dysfunction
- Impaired incretin action
#diabetes #dexcom #cgm #t2d
www.nature.com/articles/s41...
Prediction of metabolic subphenotypes of type 2 diabetes via continuous glucose monitoring and machine learning - Nature Biomedical Engineering
Metabolic subphenotypes of type 2 diabetes can be predicted by the shape of the glucose curve measured via a continuous glucose monitor during standardized oral glucose-tolerance tests performed at ho...
www.nature.com
December 26, 2024 at 10:34 PM
Interesting new paper using Dexcom cgm data and an ml model to identify 4 different sub phenotypes for type 2 diabetes.
- Muscle insulin resistance
- Hepatic insulin resistance
- β-cell dysfunction
- Impaired incretin action
#diabetes #dexcom #cgm #t2d
www.nature.com/articles/s41...
- Muscle insulin resistance
- Hepatic insulin resistance
- β-cell dysfunction
- Impaired incretin action
#diabetes #dexcom #cgm #t2d
www.nature.com/articles/s41...
I use Loop (www.dddiaz.com/post/loop/) to help manage my Diabetes. It is incredible that not only is it an open source project, it is now being included in the diabetes standard of care!
diabetesjournals.org/care/article...
#T1D #diabetes #wearenotwaiting #loop #opensource
diabetesjournals.org/care/article...
#T1D #diabetes #wearenotwaiting #loop #opensource
Loop | Daniel Diaz's Website
I have had Type 1 Diabetes for over 25 years and today on World Diabetes Day I want to celebrate the most impactful open source project I have ever used. Before I can talk about that though, I have to...
www.dddiaz.com
December 26, 2024 at 10:29 PM
I use Loop (www.dddiaz.com/post/loop/) to help manage my Diabetes. It is incredible that not only is it an open source project, it is now being included in the diabetes standard of care!
diabetesjournals.org/care/article...
#T1D #diabetes #wearenotwaiting #loop #opensource
diabetesjournals.org/care/article...
#T1D #diabetes #wearenotwaiting #loop #opensource
December 19, 2024 at 6:18 AM