Daniel Jones
@dcjones.bsky.social
Computational biologist at Fred Hutchinson Cancer Center (See my work here: https://dcjones.github.io/). I also post about baking, books, and Seattle politics.
I feel like a lot of these guys really just want to be podcasters and are annoyed at having any other responsibilities.
January 5, 2026 at 11:47 PM
I feel like a lot of these guys really just want to be podcasters and are annoyed at having any other responsibilities.
Glad we won't have to hear from this guy anymore soon bsky.app/profile/kuow...
Mike Solan, the high-profile and divisive president of the Seattle Police Officer’s Guild, is no longer seeking reelection, he announced last week. His second term ends next month.
Seattle's controversial police union leader Mike Solan to step aside
Mike Solan, the high-profile and divisive president of the Seattle Police Officer’s Guild, is no longer seeking reelection, he announced last week.
www.kuow.org
January 5, 2026 at 11:40 PM
Glad we won't have to hear from this guy anymore soon bsky.app/profile/kuow...
Please no one tell Sacks that Seattle exists
January 1, 2026 at 9:44 PM
Please no one tell Sacks that Seattle exists
This was super interesting! I wish OUP didn't charge $120 for his book 😭
December 20, 2025 at 7:08 PM
This was super interesting! I wish OUP didn't charge $120 for his book 😭
This is such a pure distillation of the city as a shopping destination view that the times loves to publish
December 20, 2025 at 5:23 PM
This is such a pure distillation of the city as a shopping destination view that the times loves to publish
"We often blame bureaucrats or red tape for the country’s paralysis. But the fault lies less in the rules than in who has the resources to weaponize them."
open.substack.com/pub/data4dem...
open.substack.com/pub/data4dem...
How Regulation by Litigation Strangled American Abundance
Environmentalists aren't blocking housing. Wealthy homeowners are.
open.substack.com
December 20, 2025 at 4:53 PM
"We often blame bureaucrats or red tape for the country’s paralysis. But the fault lies less in the rules than in who has the resources to weaponize them."
open.substack.com/pub/data4dem...
open.substack.com/pub/data4dem...
I'd strongly recommend updating, particularly if you're segmenting Visium HD or other whole-ish transcriptome data.
github.com/dcjones/pros...
github.com/dcjones/pros...
Release Version 3.1.0 · dcjones/proseg
This release fixes a serious bug affecting segmentation quality, and introduces a lot of optimizations. It's recommended that you update to this version as soon as possible, particularly if you are...
github.com
December 19, 2025 at 6:03 PM
I'd strongly recommend updating, particularly if you're segmenting Visium HD or other whole-ish transcriptome data.
github.com/dcjones/pros...
github.com/dcjones/pros...
I went all out optimizing proseg this week, and after many rounds of profiling and tinkering, the new release is as much as 1.5-4x faster and reduces memory usage by around 10%.
More importantly, I discovered and fixed a subtle bug that reduced segmentation accuracy for large gene panels!
More importantly, I discovered and fixed a subtle bug that reduced segmentation accuracy for large gene panels!
December 19, 2025 at 6:03 PM
I went all out optimizing proseg this week, and after many rounds of profiling and tinkering, the new release is as much as 1.5-4x faster and reduces memory usage by around 10%.
More importantly, I discovered and fixed a subtle bug that reduced segmentation accuracy for large gene panels!
More importantly, I discovered and fixed a subtle bug that reduced segmentation accuracy for large gene panels!
Reposted by Daniel Jones
tfw the guy who made this chart is going to be in charge of the fed
December 11, 2025 at 4:11 PM
tfw the guy who made this chart is going to be in charge of the fed
Feel like pure shit just want her back
en.wikipedia.org/wiki/Good_Ne...
en.wikipedia.org/wiki/Good_Ne...
Good Neighbor policy - Wikipedia
en.wikipedia.org
December 10, 2025 at 7:20 PM
Feel like pure shit just want her back
en.wikipedia.org/wiki/Good_Ne...
en.wikipedia.org/wiki/Good_Ne...
Your posts (plus my sister in law working at modular) have really piqued my mojo interest!
December 9, 2025 at 4:52 PM
Your posts (plus my sister in law working at modular) have really piqued my mojo interest!
It'll get fixed in a decade or so, like the "University Street" station.
December 9, 2025 at 12:29 AM
It'll get fixed in a decade or so, like the "University Street" station.
I'm somehow just discovering that there's pretty compelling deep learning framework being built in rust burn.dev/books/burn/m...
Why Burn? - The Burn Book 🔥
burn.dev
December 7, 2025 at 5:51 PM
I'm somehow just discovering that there's pretty compelling deep learning framework being built in rust burn.dev/books/burn/m...
We're in a golden age of How Its Made style content on YouTube these days. One of my faves is the Korean channel "All Process of World" youtu.be/GE29Df9q7cU
How to Make Prosthetic Arm for Handless People. Korean Artificial Body Part Making Company
YouTube video by All process of world
youtu.be
December 7, 2025 at 4:23 PM
We're in a golden age of How Its Made style content on YouTube these days. One of my faves is the Korean channel "All Process of World" youtu.be/GE29Df9q7cU
Reposted by Daniel Jones
Congratulations to Seattle's Sound Transit, America's fastest-growing train network, which is opening an 8-mile, 3-station extension to Federal Way today!
This is the system's 4th new segment opened in less than 2 years, continually pushing ridership up to new record highs!
This is the system's 4th new segment opened in less than 2 years, continually pushing ridership up to new record highs!
December 6, 2025 at 8:56 PM
Congratulations to Seattle's Sound Transit, America's fastest-growing train network, which is opening an 8-mile, 3-station extension to Federal Way today!
This is the system's 4th new segment opened in less than 2 years, continually pushing ridership up to new record highs!
This is the system's 4th new segment opened in less than 2 years, continually pushing ridership up to new record highs!
Reposted by Daniel Jones
Pew's main findings:
- Newer multifamily is safer than older multifamily
- Newer multifamily is safer than newer single-family
- Single-stair multifamily buildings are as safe as buildings with two stairwells
www.lewis.ucla.edu/2025/12/03/1...
- Newer multifamily is safer than older multifamily
- Newer multifamily is safer than newer single-family
- Single-stair multifamily buildings are as safe as buildings with two stairwells
www.lewis.ucla.edu/2025/12/03/1...
Episode 103: Fire Safety in Multifamily Housing with Alex Horowitz (Incentives Series pt. 6)
Explore why multifamily homes are often safer from fires than single-family housing, as Alex Horowitz shares research on building age, fire risk, and single-stair safety in our Incentives Series.
www.lewis.ucla.edu
December 3, 2025 at 5:44 PM
Pew's main findings:
- Newer multifamily is safer than older multifamily
- Newer multifamily is safer than newer single-family
- Single-stair multifamily buildings are as safe as buildings with two stairwells
www.lewis.ucla.edu/2025/12/03/1...
- Newer multifamily is safer than older multifamily
- Newer multifamily is safer than newer single-family
- Single-stair multifamily buildings are as safe as buildings with two stairwells
www.lewis.ucla.edu/2025/12/03/1...
2020 me: 64GB should be enough for my workstation
2025 me: hmm should I upgrade my ram or pay rent this month?
2025 me: hmm should I upgrade my ram or pay rent this month?
December 3, 2025 at 9:06 PM
2020 me: 64GB should be enough for my workstation
2025 me: hmm should I upgrade my ram or pay rent this month?
2025 me: hmm should I upgrade my ram or pay rent this month?
I'm never going to be able to afford memory again. Might just pivot all my work towards probabilistic data structures and online stats.
www.reuters.com/business/mic...
www.reuters.com/business/mic...
Micron to exit consumer memory business amid global supply shortage
Memory chipmaker Micron Technology said on Wednesday it will exit its consumer business, as it doubles down on advanced memory chips used in artificial intelligence data centers amid a global supply s...
www.reuters.com
December 3, 2025 at 7:26 PM
I'm never going to be able to afford memory again. Might just pivot all my work towards probabilistic data structures and online stats.
www.reuters.com/business/mic...
www.reuters.com/business/mic...
I don't understand what the passageway stairs lead to. I guess doors will be figured out later?
December 2, 2025 at 12:40 AM
I don't understand what the passageway stairs lead to. I guess doors will be figured out later?
I will vote for any dem promising another Master and Commander film
November 25, 2025 at 5:05 PM
I will vote for any dem promising another Master and Commander film
Welcome back to the platform for people who actually read books!
November 25, 2025 at 4:59 PM
Welcome back to the platform for people who actually read books!
It's gotta be "The Black Jacobins". An incredibly gripping narrative of a neglected and consequential history.
November 19, 2025 at 11:39 PM
It's gotta be "The Black Jacobins". An incredibly gripping narrative of a neglected and consequential history.
Yes! We need more of whatever the nonfiction equivalent of a novella is.
November 19, 2025 at 4:05 AM
Yes! We need more of whatever the nonfiction equivalent of a novella is.
Lingonberry cruffins. Going full Scandinavia mode lately.
November 17, 2025 at 5:05 PM
Lingonberry cruffins. Going full Scandinavia mode lately.
Reposted by Daniel Jones
Seen our Transit Tracker project on social media? You can learn how to build your own here: transit-tracker.eastsideurbanism.org
Transit Tracker
Transit Tracker is a DIY customizable public transit arrivals board for your home.
transit-tracker.eastsideurbanism.org
November 16, 2025 at 5:46 AM
Seen our Transit Tracker project on social media? You can learn how to build your own here: transit-tracker.eastsideurbanism.org