@davidadambarr.bsky.social
Infectious diseases clinician, Glasgow.
Reposted
The biologist's view of how flight works. Courtesy of Rory Maizels. #GenerativeBiology
October 21, 2025 at 1:40 PM
The biologist's view of how flight works. Courtesy of Rory Maizels. #GenerativeBiology
Reposted
⚡️New preprint (not peer-reviewed)⚡️
In the SaDAPT trial with people with #HIV and #tuberculosis symptoms in 🇲🇼🇱🇸, we investigated if antiretroviral therapy should be initiated immediately, or delayed until TB results available. ssrn.com/abstract=523...
Outcomes (incl. IRIS) similar across both arms.
In the SaDAPT trial with people with #HIV and #tuberculosis symptoms in 🇲🇼🇱🇸, we investigated if antiretroviral therapy should be initiated immediately, or delayed until TB results available. ssrn.com/abstract=523...
Outcomes (incl. IRIS) similar across both arms.
May 1, 2025 at 7:10 AM
⚡️New preprint (not peer-reviewed)⚡️
In the SaDAPT trial with people with #HIV and #tuberculosis symptoms in 🇲🇼🇱🇸, we investigated if antiretroviral therapy should be initiated immediately, or delayed until TB results available. ssrn.com/abstract=523...
Outcomes (incl. IRIS) similar across both arms.
In the SaDAPT trial with people with #HIV and #tuberculosis symptoms in 🇲🇼🇱🇸, we investigated if antiretroviral therapy should be initiated immediately, or delayed until TB results available. ssrn.com/abstract=523...
Outcomes (incl. IRIS) similar across both arms.
Reposted
This is why clinical trials are important. Unfortunately tecovirimat did not improve resolution of clade IIb mpox compared to placebo.
There are currently no effective antivirals for the treatment of mpox and this is an urgent need. Disappointing result but at least we know.
There are currently no effective antivirals for the treatment of mpox and this is an urgent need. Disappointing result but at least we know.
Turns out the antiviral TPOXX (tecovirimat) doesn't work for mild/moderate Clade II #mpox ( #monkeypox) either, as previously shown for Clade I. Many treated people reported improvement, but symptoms typically resolve anyway -- that's why we need controlled trials.
www.niaid.nih.gov/news-events/...
www.niaid.nih.gov/news-events/...
NIH Study Finds Tecovirimat Was Safe but Did Not Improve Mpox Resolution or Pain
Tecovirimat was safe but did not reduce the time to lesion resolution or reduce pain among adults with mild to moderate clade II mpox and a low risk of severe disease in an international study.
www.niaid.nih.gov
December 10, 2024 at 8:45 PM
This is why clinical trials are important. Unfortunately tecovirimat did not improve resolution of clade IIb mpox compared to placebo.
There are currently no effective antivirals for the treatment of mpox and this is an urgent need. Disappointing result but at least we know.
There are currently no effective antivirals for the treatment of mpox and this is an urgent need. Disappointing result but at least we know.
Reposted
Reposted
To reiterate - if we could find our new journal content on here - also BMJ, Lancet, NEJM, JAMA - it would be just perfect and all could deactivate accounts at the old place…which no longer seems somewhere for medicine and research
Academic publishers at Science, Nature, Elsevier, Wiley, OUP - are you going to be using #Bluesky to post and publicise your new content - it’s where we’ll now be looking for stuff
November 16, 2024 at 6:17 AM
To reiterate - if we could find our new journal content on here - also BMJ, Lancet, NEJM, JAMA - it would be just perfect and all could deactivate accounts at the old place…which no longer seems somewhere for medicine and research
👌
Precision Medicine is just a five-dollar term for Diagnosis.
November 7, 2024 at 2:36 PM
👌
Reposted
DYK in 1957, Glasgow, Scotland ran the largest ever screening campaign against #tuberculosis?
715,000 people (76% of entire adult population) were X-rayed over just 5 weeks!
In a new study, we looked at the long-term impact of this campaign. journals.plos.org/plosmedicine...
#episky #idsky 🧪🛟
715,000 people (76% of entire adult population) were X-rayed over just 5 weeks!
In a new study, we looked at the long-term impact of this campaign. journals.plos.org/plosmedicine...
#episky #idsky 🧪🛟
November 5, 2024 at 8:29 PM
DYK in 1957, Glasgow, Scotland ran the largest ever screening campaign against #tuberculosis?
715,000 people (76% of entire adult population) were X-rayed over just 5 weeks!
In a new study, we looked at the long-term impact of this campaign. journals.plos.org/plosmedicine...
#episky #idsky 🧪🛟
715,000 people (76% of entire adult population) were X-rayed over just 5 weeks!
In a new study, we looked at the long-term impact of this campaign. journals.plos.org/plosmedicine...
#episky #idsky 🧪🛟
Reposted
Our hybdid meeting on indirects effects of CMV infection is ONLY 1 WEEK AWAY
Not too late to snap up FREE TICKETS
Sessions on paediatrics, immunocompromised host, CMV-TB and critical illness/immunosenescence
Keynote from STANLEY PLOTKIN!
royalsociety.org/science-even...
#IDsky #virology #episky
Not too late to snap up FREE TICKETS
Sessions on paediatrics, immunocompromised host, CMV-TB and critical illness/immunosenescence
Keynote from STANLEY PLOTKIN!
royalsociety.org/science-even...
#IDsky #virology #episky
The indirect effects of cytomegalovirus infection: mechanisms and consequences | Royal Society
Discussion meeting organised by Professor Tom Yates and Professor Helen Payne on the indirect effects of cytomegalovirus infection.
royalsociety.org
October 7, 2024 at 9:53 AM
Our hybdid meeting on indirects effects of CMV infection is ONLY 1 WEEK AWAY
Not too late to snap up FREE TICKETS
Sessions on paediatrics, immunocompromised host, CMV-TB and critical illness/immunosenescence
Keynote from STANLEY PLOTKIN!
royalsociety.org/science-even...
#IDsky #virology #episky
Not too late to snap up FREE TICKETS
Sessions on paediatrics, immunocompromised host, CMV-TB and critical illness/immunosenescence
Keynote from STANLEY PLOTKIN!
royalsociety.org/science-even...
#IDsky #virology #episky