Daniel Yu
@danielsyu.bsky.social
Postdoc in the Banfield lab @ John Innes Centre | PhD in the Williams lab @ ANU | Plant immune receptor engineering 🌾 | Fungal effectors 🍄 | Structural biology 💎 | 🇦🇺
Reposted by Daniel Yu
Hello bluesky
January 16, 2026 at 12:05 AM
Hello bluesky
Reposted by Daniel Yu
Tandem Kinases containing HMA domains can be engineered to sense additional effectors. Parallels with NLR HMA engineering and highlights the versatility of this interesting integrated domain. www.biorxiv.org/content/10.6...
Engineering plant tandem kinase immune receptors expands effector recognition profiles
Plant intracellular immune receptors are widely deployed in breeding to protect crops from disease. In addition to nucleotide-binding leucine-rich repeat receptors (NLRs), tandem kinase proteins (TKPs...
www.biorxiv.org
December 16, 2025 at 4:32 PM
Tandem Kinases containing HMA domains can be engineered to sense additional effectors. Parallels with NLR HMA engineering and highlights the versatility of this interesting integrated domain. www.biorxiv.org/content/10.6...
Reposted by Daniel Yu
Another exciting preprint! Two additional HMA-TKP sensors from wheat and barley, swapping HMAs can confer recognition specificity. Evo analyses supporting HMA-TKP has differentiated to recognize different effectors through HMA diversification. other links below. www.biorxiv.org/content/10.6...
Evolution of HMA-integrated tandem kinases accompanied by expansion of target pathogens
Tandem kinase proteins (TKPs) are an emerging family of plant intracellular immune receptors that offer potential for developing novel disease resistance. We cloned Rmo2 and Rwt7, genes for resistance...
www.biorxiv.org
December 17, 2025 at 6:25 PM
Another exciting preprint! Two additional HMA-TKP sensors from wheat and barley, swapping HMAs can confer recognition specificity. Evo analyses supporting HMA-TKP has differentiated to recognize different effectors through HMA diversification. other links below. www.biorxiv.org/content/10.6...
Reposted by Daniel Yu
Super-happy sharing my Lab's new work on engineering plant HMA-containing tandem kinase immune receptors. Congrats to all authors (@danielsyu.bsky.social and @njw33.bsky.social on here). Work only possible in collaboration with Soichiro Asuke. See linked paper to follow!
bsky.app/profile/bior...
bsky.app/profile/bior...
Engineering plant tandem kinase immune receptors expands effector recognition profiles https://www.biorxiv.org/content/10.64898/2025.12.15.694194v1
December 16, 2025 at 5:55 PM
Super-happy sharing my Lab's new work on engineering plant HMA-containing tandem kinase immune receptors. Congrats to all authors (@danielsyu.bsky.social and @njw33.bsky.social on here). Work only possible in collaboration with Soichiro Asuke. See linked paper to follow!
bsky.app/profile/bior...
bsky.app/profile/bior...
Excited to share our #plantimmunity preprint on engineering cereal TKPs
www.biorxiv.org/content/10.6...
A short thread below 👇
www.biorxiv.org/content/10.6...
A short thread below 👇
Engineering plant tandem kinase immune receptors expands effector recognition profiles
Plant intracellular immune receptors are widely deployed in breeding to protect crops from disease. In addition to nucleotide-binding leucine-rich repeat receptors (NLRs), tandem kinase proteins (TKPs...
www.biorxiv.org
December 16, 2025 at 5:37 PM
Excited to share our #plantimmunity preprint on engineering cereal TKPs
www.biorxiv.org/content/10.6...
A short thread below 👇
www.biorxiv.org/content/10.6...
A short thread below 👇
Excited to share our review on structure-based engineering of NLRs in plant immunity. We also have some cool plant immunity engineering stories coming out this month so watch this space! #plantimmunity #nlr
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Architects of plant immunity: Structure-informed strategies for engineering plant nucleotide-binding leucine-rich repeat receptors
Diseases caused by plant pathogens are a major factor decreasing crop yields that lead to food insecurity. To protect against pathogen threats, plants…
www.sciencedirect.com
December 1, 2025 at 11:15 PM
Excited to share our review on structure-based engineering of NLRs in plant immunity. We also have some cool plant immunity engineering stories coming out this month so watch this space! #plantimmunity #nlr
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Daniel Yu
Registrations are rolling in for the 2025 Stromlo Plant Pathology meeting in Canberra (Nov 27–28)! Secure your spot! Speakers: @yasukadota.bsky.social, Cecille Segonzac, @thamlab.bsky.social, @yichangsung.bsky.social, Tek Tay & @danielsyu.bsky.social. Register at tinyurl.com/3e3tx9j2
#strompath25
#strompath25
10th Stromlo Plant Pathology Conference | wheatbiosecurity
tinyurl.com
August 20, 2025 at 4:53 AM
Registrations are rolling in for the 2025 Stromlo Plant Pathology meeting in Canberra (Nov 27–28)! Secure your spot! Speakers: @yasukadota.bsky.social, Cecille Segonzac, @thamlab.bsky.social, @yichangsung.bsky.social, Tek Tay & @danielsyu.bsky.social. Register at tinyurl.com/3e3tx9j2
#strompath25
#strompath25
Super excited to be giving a talk at #2025ISMPMI today in the Synthetic biology concurrent session from 15:15 - 15:35! Come along if you’re interested in engineering Tandem Kinase Proteins
July 17, 2025 at 5:51 AM
Super excited to be giving a talk at #2025ISMPMI today in the Synthetic biology concurrent session from 15:15 - 15:35! Come along if you’re interested in engineering Tandem Kinase Proteins
Reposted by Daniel Yu
GROUP LEADER VACANCY
JIC is recruiting a Group Leader in Discovery Plant Sciences.
If you think your research would synergise and thrive at JIC, please apply.
www.jic.ac.uk/vacancies/gr...
JIC is recruiting a Group Leader in Discovery Plant Sciences.
If you think your research would synergise and thrive at JIC, please apply.
www.jic.ac.uk/vacancies/gr...
Group Leader in Discovery Plant Sciences | John Innes Centre
The John Innes Centre (JIC) seeks a visionary Group Leader to lead research on Discovery Plant Science.
www.jic.ac.uk
July 16, 2025 at 10:46 AM
GROUP LEADER VACANCY
JIC is recruiting a Group Leader in Discovery Plant Sciences.
If you think your research would synergise and thrive at JIC, please apply.
www.jic.ac.uk/vacancies/gr...
JIC is recruiting a Group Leader in Discovery Plant Sciences.
If you think your research would synergise and thrive at JIC, please apply.
www.jic.ac.uk/vacancies/gr...
Reposted by Daniel Yu
Our Research Briefing on the tandem kinase proteins paper is online now!
Curious about the story behind our TKP paper?
📄 Research Briefing: www.nature.com/articles/s41...
📄 Research article: www.nature.com/articles/s41...
Curious about the story behind our TKP paper?
📄 Research Briefing: www.nature.com/articles/s41...
📄 Research article: www.nature.com/articles/s41...
A plant dual-kinase protein traps a pathogen effector to trigger immunity - Nature Genetics
Tandem kinase proteins (TKPs) are key regulators of plant immunity. We found that RWT4, a wheat TKP, confers resistance to the fungal pathogen Magnaporthe oryzae by directly recognizing the effector A...
www.nature.com
April 25, 2025 at 6:30 PM
Our Research Briefing on the tandem kinase proteins paper is online now!
Curious about the story behind our TKP paper?
📄 Research Briefing: www.nature.com/articles/s41...
📄 Research article: www.nature.com/articles/s41...
Curious about the story behind our TKP paper?
📄 Research Briefing: www.nature.com/articles/s41...
📄 Research article: www.nature.com/articles/s41...
Reposted by Daniel Yu
Its out....
Plant pathogenic fungi hijack phosphate signaling with conserved enzymatic effectors | Science www.science.org/doi/10.1126/...
A wonderful collaboration with the Schaffrath @rwth.bsky.social and Oliveira-Garcia groups! Huge credit to Carl Mcombe and Alex Wegner.
Plant pathogenic fungi hijack phosphate signaling with conserved enzymatic effectors | Science www.science.org/doi/10.1126/...
A wonderful collaboration with the Schaffrath @rwth.bsky.social and Oliveira-Garcia groups! Huge credit to Carl Mcombe and Alex Wegner.
Plant pathogenic fungi hijack phosphate signaling with conserved enzymatic effectors
Inorganic phosphate (Pi) is essential for life, and plant cells monitor Pi availability by sensing inositol pyrophosphate (PP-InsP) levels. In this work, we describe the hijacking of plant phosphate s...
www.science.org
February 28, 2025 at 8:52 AM
Its out....
Plant pathogenic fungi hijack phosphate signaling with conserved enzymatic effectors | Science www.science.org/doi/10.1126/...
A wonderful collaboration with the Schaffrath @rwth.bsky.social and Oliveira-Garcia groups! Huge credit to Carl Mcombe and Alex Wegner.
Plant pathogenic fungi hijack phosphate signaling with conserved enzymatic effectors | Science www.science.org/doi/10.1126/...
A wonderful collaboration with the Schaffrath @rwth.bsky.social and Oliveira-Garcia groups! Huge credit to Carl Mcombe and Alex Wegner.
Reposted by Daniel Yu
HI old friends! Finally took the leap here to say I have several open positions going in my lab at the moment (and more to come).
1) PhD studentship in collaboration with the Royal Horticultural Society (genomics)
2) Biochemistry Postdoc to understand how Starships move
Check out the links below!
1) PhD studentship in collaboration with the Royal Horticultural Society (genomics)
2) Biochemistry Postdoc to understand how Starships move
Check out the links below!
December 7, 2024 at 12:00 PM
HI old friends! Finally took the leap here to say I have several open positions going in my lab at the moment (and more to come).
1) PhD studentship in collaboration with the Royal Horticultural Society (genomics)
2) Biochemistry Postdoc to understand how Starships move
Check out the links below!
1) PhD studentship in collaboration with the Royal Horticultural Society (genomics)
2) Biochemistry Postdoc to understand how Starships move
Check out the links below!
Reposted by Daniel Yu
If you're from the UK and are looking for a PhD, don't miss out on this fantastic opportunity! Amazing lab and amazing project!
📢 PhD Opportunity in my lab on Plant Immune Receptor Bioengineering at @imperiallifesci.bsky.social
🌱 Start: October 2025
📅 Deadline: 12th January 2025
🇬🇧 Open to UK students
💰 Fully funded
ℹ️ More info: tinyurl.com/w6ap9v9f
❗ #PlantImmunity #PlantPathology
🙏 Please share with interested candidates!
🌱 Start: October 2025
📅 Deadline: 12th January 2025
🇬🇧 Open to UK students
💰 Fully funded
ℹ️ More info: tinyurl.com/w6ap9v9f
❗ #PlantImmunity #PlantPathology
🙏 Please share with interested candidates!
Bioengineering of plant NLR (nucleotide-binding leucine-rich repeat) immune receptors to enhance disease resistance at Imperial College London on FindAPhD.com
PhD Project - Bioengineering of plant NLR (nucleotide-binding leucine-rich repeat) immune receptors to enhance disease resistance at Imperial College London, listed on FindAPhD.com
www.findaphd.com
December 4, 2024 at 12:59 PM
If you're from the UK and are looking for a PhD, don't miss out on this fantastic opportunity! Amazing lab and amazing project!
Reposted by Daniel Yu
In case you missed it, here is the TSL Autumn Symposium 2024 in full 🍿
November 18, 2024 at 6:18 PM
In case you missed it, here is the TSL Autumn Symposium 2024 in full 🍿
Reposted by Daniel Yu
📣 PhD opportunity at @thesainsburylab.bsky.social Norwich, UK.
"Investigating host penetration by the rice blast fungus" with Dr Frank Menke and Nick Talbot
@FrankMenke.bsky.social @talbotlabtsl.bsky.social
Apply before 25 Nov 2024! ⬇️
biodtp.norwichresearchpark.ac.uk/projects/inv...
"Investigating host penetration by the rice blast fungus" with Dr Frank Menke and Nick Talbot
@FrankMenke.bsky.social @talbotlabtsl.bsky.social
Apply before 25 Nov 2024! ⬇️
biodtp.norwichresearchpark.ac.uk/projects/inv...
November 18, 2024 at 5:45 PM
📣 PhD opportunity at @thesainsburylab.bsky.social Norwich, UK.
"Investigating host penetration by the rice blast fungus" with Dr Frank Menke and Nick Talbot
@FrankMenke.bsky.social @talbotlabtsl.bsky.social
Apply before 25 Nov 2024! ⬇️
biodtp.norwichresearchpark.ac.uk/projects/inv...
"Investigating host penetration by the rice blast fungus" with Dr Frank Menke and Nick Talbot
@FrankMenke.bsky.social @talbotlabtsl.bsky.social
Apply before 25 Nov 2024! ⬇️
biodtp.norwichresearchpark.ac.uk/projects/inv...
Reposted by Daniel Yu
So many keen peeps interested in structural biology.. we have a new unit cell. 🧶🧬
go.bsky.app/HByHiW6
go.bsky.app/HByHiW6
November 17, 2024 at 11:07 AM
So many keen peeps interested in structural biology.. we have a new unit cell. 🧶🧬
go.bsky.app/HByHiW6
go.bsky.app/HByHiW6
Reposted by Daniel Yu
I created this Starter Pack for PhDs and Postdocs in Structural Biology to help connect with colleagues who share similar interests and concerns in the field.
Feel free to recommend people or yourself! I'll be adding people 💪🏼😁
bsky.app/starter-pack...
Feel free to recommend people or yourself! I'll be adding people 💪🏼😁
bsky.app/starter-pack...
November 16, 2024 at 10:38 PM
I created this Starter Pack for PhDs and Postdocs in Structural Biology to help connect with colleagues who share similar interests and concerns in the field.
Feel free to recommend people or yourself! I'll be adding people 💪🏼😁
bsky.app/starter-pack...
Feel free to recommend people or yourself! I'll be adding people 💪🏼😁
bsky.app/starter-pack...
Reposted by Daniel Yu
Hello new Plant Scientists,
To get you started, the two #PlantScience Research #StarterPacks will connect you to other Scientists & relevant feeds:
1) go.bsky.app/8Zfmwf7
2) go.bsky.app/3NcqRCE
You can find more relevant Plant Science feeds here:
bsky.app/profile/soms...
Further... 1/2
To get you started, the two #PlantScience Research #StarterPacks will connect you to other Scientists & relevant feeds:
1) go.bsky.app/8Zfmwf7
2) go.bsky.app/3NcqRCE
You can find more relevant Plant Science feeds here:
bsky.app/profile/soms...
Further... 1/2
November 16, 2024 at 7:49 PM
Hello new Plant Scientists,
To get you started, the two #PlantScience Research #StarterPacks will connect you to other Scientists & relevant feeds:
1) go.bsky.app/8Zfmwf7
2) go.bsky.app/3NcqRCE
You can find more relevant Plant Science feeds here:
bsky.app/profile/soms...
Further... 1/2
To get you started, the two #PlantScience Research #StarterPacks will connect you to other Scientists & relevant feeds:
1) go.bsky.app/8Zfmwf7
2) go.bsky.app/3NcqRCE
You can find more relevant Plant Science feeds here:
bsky.app/profile/soms...
Further... 1/2
First post on bluesky! Sharing some photogenic protein crystals I got a few months back 💎. Shame they didn’t diffract as well as they look
November 15, 2024 at 8:12 AM
First post on bluesky! Sharing some photogenic protein crystals I got a few months back 💎. Shame they didn’t diffract as well as they look
Reposted by Daniel Yu
Hi everyone,
I created a starter pack for all fungal biologists.
Tell me who I should add or if you want to be part of it!
#fungi
go.bsky.app/12PCCjU
I created a starter pack for all fungal biologists.
Tell me who I should add or if you want to be part of it!
#fungi
go.bsky.app/12PCCjU
November 14, 2024 at 9:57 PM
Hi everyone,
I created a starter pack for all fungal biologists.
Tell me who I should add or if you want to be part of it!
#fungi
go.bsky.app/12PCCjU
I created a starter pack for all fungal biologists.
Tell me who I should add or if you want to be part of it!
#fungi
go.bsky.app/12PCCjU