Sam Pastva
@daemontus.bsky.social
Unexpectedly jolly sack of bones and tissue. Writing scientific papers about computational biology.
Reposted by Sam Pastva
Tired: pausing mid-heist to eat 10 cheese wheels
Wired: pausing mid-heist to read the extended edition of the Lusty Argonian Maid
Wired: pausing mid-heist to read the extended edition of the Lusty Argonian Maid
October 14, 2025 at 5:55 PM
Tired: pausing mid-heist to eat 10 cheese wheels
Wired: pausing mid-heist to read the extended edition of the Lusty Argonian Maid
Wired: pausing mid-heist to read the extended edition of the Lusty Argonian Maid
Reposted by Sam Pastva
In case you're interested, I wrote up my nerdy analysis of the economics of installing solar panels on my house: schiff.nz/blog/nerding...
August 6, 2025 at 4:05 AM
In case you're interested, I wrote up my nerdy analysis of the economics of installing solar panels on my house: schiff.nz/blog/nerding...
Reposted by Sam Pastva
As you may know, the tallest mountain in our solar system is Olympus Mons on Mars. But mountain heights on earth are measured from sea level. How do we measure the height of a mountain on a planet with no oceans?
1/7 ⚛️🧪
1/7 ⚛️🧪
July 7, 2025 at 9:15 PM
As you may know, the tallest mountain in our solar system is Olympus Mons on Mars. But mountain heights on earth are measured from sea level. How do we measure the height of a mountain on a planet with no oceans?
1/7 ⚛️🧪
1/7 ⚛️🧪
Today I have another paper to share which was very fun to write :)
Here, we investigate correspondence between attractors and minimal trap spaces and actually quantify the common assumption that motif-avoidant attractors are rare in realistic models.
link.springer.com/article/10.1...
Here, we investigate correspondence between attractors and minimal trap spaces and actually quantify the common assumption that motif-avoidant attractors are rare in realistic models.
link.springer.com/article/10.1...
An open problem: Why are motif-avoidant attractors so rare in asynchronous Boolean networks? - Journal of Mathematical Biology
Asynchronous Boolean networks are a type of discrete dynamical system in which each variable can take one of two states, and a single variable state is updated in each time step according to pre-selec...
link.springer.com
June 19, 2025 at 7:58 AM
Today I have another paper to share which was very fun to write :)
Here, we investigate correspondence between attractors and minimal trap spaces and actually quantify the common assumption that motif-avoidant attractors are rare in realistic models.
link.springer.com/article/10.1...
Here, we investigate correspondence between attractors and minimal trap spaces and actually quantify the common assumption that motif-avoidant attractors are rare in realistic models.
link.springer.com/article/10.1...
Reposted by Sam Pastva
Got to present my art project on flower genetic design to a room full of chaotic and charismatic scientists at Woodstock Bio2 in Prague 🤘
Life is cool. #TCTeAC #theconferencetoendallconferences
Life is cool. #TCTeAC #theconferencetoendallconferences
June 14, 2025 at 10:36 AM
Got to present my art project on flower genetic design to a room full of chaotic and charismatic scientists at Woodstock Bio2 in Prague 🤘
Life is cool. #TCTeAC #theconferencetoendallconferences
Life is cool. #TCTeAC #theconferencetoendallconferences
Reposted by Sam Pastva
I Let ChatGPT Make All My Architectural Decisions for a Month: The Surprising Results https://lobste.rs/s/spmwde ##vibecoding
I Let ChatGPT Make All My Architectural Decisions for a Month: The Surprising Results
“We should use event sourcing with CQRS for this project,” declared the AI confidently. “It’s the most appropriate pattern given your…
medium.com
June 6, 2025 at 11:30 AM
I Let ChatGPT Make All My Architectural Decisions for a Month: The Surprising Results https://lobste.rs/s/spmwde ##vibecoding
Reposted by Sam Pastva
Our paper on mapping attractor landscapes is now available through Bioinformatics!
The tool, Biobalm, is the fastest I know of for computing and analyzing attractors in Boolean networks. If that's something you are interested in, give it a try :)
doi.org/10.1093/bioi...
The tool, Biobalm, is the fastest I know of for computing and analyzing attractors in Boolean networks. If that's something you are interested in, give it a try :)
doi.org/10.1093/bioi...
Mapping the attractor landscape of Boolean networks with biobalm
AbstractMotivation. Boolean networks are popular dynamical models of cellular processes in systems biology. Their attractors model phenotypes that arise fr
doi.org
May 9, 2025 at 10:54 AM
Our paper on mapping attractor landscapes is now available through Bioinformatics!
The tool, Biobalm, is the fastest I know of for computing and analyzing attractors in Boolean networks. If that's something you are interested in, give it a try :)
doi.org/10.1093/bioi...
The tool, Biobalm, is the fastest I know of for computing and analyzing attractors in Boolean networks. If that's something you are interested in, give it a try :)
doi.org/10.1093/bioi...
Reposted by Sam Pastva
Reposted by Sam Pastva
Reposted by Sam Pastva
"AI work is just as good as human work" is a statement that *always* flows from the direction of power. Employers to workers, producers to consumers, but not the reverse.
Because it's not a thing people actually believe, but an argument: slop is good enough for you; you are slop.
Because it's not a thing people actually believe, but an argument: slop is good enough for you; you are slop.
April 15, 2025 at 2:47 PM
"AI work is just as good as human work" is a statement that *always* flows from the direction of power. Employers to workers, producers to consumers, but not the reverse.
Because it's not a thing people actually believe, but an argument: slop is good enough for you; you are slop.
Because it's not a thing people actually believe, but an argument: slop is good enough for you; you are slop.
Reposted by Sam Pastva
Bluesky is all fun and jokes but if you want to learn something you go to Mastodon
April 15, 2025 at 11:46 AM
Bluesky is all fun and jokes but if you want to learn something you go to Mastodon
I don't agree with everything here, but yes, this largely rings true.
Especially regarding the reading and *writing* abilities. I can teach people to write rather nice programs, but writing text for humans to read is a rather Sisyphean task.
hilariusbookbinder.substack.com/p/the-averag...
Especially regarding the reading and *writing* abilities. I can teach people to write rather nice programs, but writing text for humans to read is a rather Sisyphean task.
hilariusbookbinder.substack.com/p/the-averag...
The average college student today
How things have changed
hilariusbookbinder.substack.com
April 1, 2025 at 2:39 PM
I don't agree with everything here, but yes, this largely rings true.
Especially regarding the reading and *writing* abilities. I can teach people to write rather nice programs, but writing text for humans to read is a rather Sisyphean task.
hilariusbookbinder.substack.com/p/the-averag...
Especially regarding the reading and *writing* abilities. I can teach people to write rather nice programs, but writing text for humans to read is a rather Sisyphean task.
hilariusbookbinder.substack.com/p/the-averag...
Reposted by Sam Pastva
But on the plus side, this makes it much more likely that in the future you will be able to behead Pikachu
Pokemon Go sale to a Saudi Arabian company owned by govt comes with six separate corporate announcement blogs, not one of them directly addressing what happens to 100 million people's location data, AR mapping capabilities, or the AI maps they have been training:
www.404media.co/saudi-arabia...
www.404media.co/saudi-arabia...
Saudi Arabia Buys Pokémon Go, and Probably All of Your Location Data
A company founded by the Saudi Arabian Public Investment Fund just bought the most popular AR video game of all time.
www.404media.co
March 12, 2025 at 5:30 PM
But on the plus side, this makes it much more likely that in the future you will be able to behead Pikachu
Reposted by Sam Pastva
Perspectives from the Technical University of Munich https://lobste.rs/s/1cqlzd ##education
Perspectives from the Technical University of Munich
A comparision of university policies in the US vs European universities regarding extracurrucular work.
mirawelner.com
March 12, 2025 at 2:00 AM
Perspectives from the Technical University of Munich https://lobste.rs/s/1cqlzd ##education
Reposted by Sam Pastva
Koment:"...this inspired me to stop playing 🎸..." 🤣
youtu.be/RCGGG9piAGY?...
youtu.be/RCGGG9piAGY?...
The Entertainer
YouTube video by LMRMAX
youtu.be
March 2, 2025 at 6:20 PM
Koment:"...this inspired me to stop playing 🎸..." 🤣
youtu.be/RCGGG9piAGY?...
youtu.be/RCGGG9piAGY?...
It's coming together... The OpenFlexture digital microscope. Still waiting for some electronics, but hopefully we'll get first pictures out of it soon...
February 25, 2025 at 8:57 AM
It's coming together... The OpenFlexture digital microscope. Still waiting for some electronics, but hopefully we'll get first pictures out of it soon...
Reposted by Sam Pastva
‼️🔬 We start!!! 🎉🤖
Super exciting!!! After years of teaching courses for #DeepLearning for Microscopy and Life Science application, we start today our first “advanced course” @embl.org!
#EMBLDeepLearning
Super exciting!!! After years of teaching courses for #DeepLearning for Microscopy and Life Science application, we start today our first “advanced course” @embl.org!
#EMBLDeepLearning
February 17, 2025 at 8:37 AM
‼️🔬 We start!!! 🎉🤖
Super exciting!!! After years of teaching courses for #DeepLearning for Microscopy and Life Science application, we start today our first “advanced course” @embl.org!
#EMBLDeepLearning
Super exciting!!! After years of teaching courses for #DeepLearning for Microscopy and Life Science application, we start today our first “advanced course” @embl.org!
#EMBLDeepLearning
Reposted by Sam Pastva
Me: [glances in the general direction of the bathroom]
Shampoo bottles in the shower that I absolutely did not touch:
Shampoo bottles in the shower that I absolutely did not touch:
an aerial view of a city with lots of tall buildings and a building that says ' chinese ' on it
Alt: A bunch of buildings collapsing
media.tenor.com
February 8, 2025 at 6:51 PM
Me: [glances in the general direction of the bathroom]
Shampoo bottles in the shower that I absolutely did not touch:
Shampoo bottles in the shower that I absolutely did not touch:
Reposted by Sam Pastva
Microsoft's own research confirms something that was already pretty obvious: relying on a text generating machine to come up with answers erodes critical thinking, and is a method favoured by those who never liked doing critical thinking in the first place
advait.org/files/lee_20...
advait.org/files/lee_20...
advait.org
February 9, 2025 at 10:15 AM
Microsoft's own research confirms something that was already pretty obvious: relying on a text generating machine to come up with answers erodes critical thinking, and is a method favoured by those who never liked doing critical thinking in the first place
advait.org/files/lee_20...
advait.org/files/lee_20...
Reposted by Sam Pastva
On top of everything else, David Lynch had one of the greatest heads of hair in history.
January 16, 2025 at 8:57 PM
On top of everything else, David Lynch had one of the greatest heads of hair in history.
Reposted by Sam Pastva
