David Taborsky
@dadita.bsky.social
PhD Student | Developmental Biology | Sendoel Lab @ UZH
Working on gastruloids, CRISPR Screens and translational regulation
Fascinated by development, regeneration and cancer
Working on gastruloids, CRISPR Screens and translational regulation
Fascinated by development, regeneration and cancer
After almost 6 years my PhD journey came to an end! It has been a wild ride and I’m incredibly grateful for all the things I learned and the people I have met, especially the other members of the @sendoellab.bsky.social.
I am also looking forward to my next chapter at the FGCZ!
I am also looking forward to my next chapter at the FGCZ!
The summer of defenses comes to an end! Huge congratulations to David (@dadita.bsky.social ) on a brillant PhD and thank you for everything you have done to shape our lab community from day 1 on. We’re thrilled you’re staying in Zurich and wish you all the best in your next chapter!
October 31, 2025 at 12:36 PM
After almost 6 years my PhD journey came to an end! It has been a wild ride and I’m incredibly grateful for all the things I learned and the people I have met, especially the other members of the @sendoellab.bsky.social.
I am also looking forward to my next chapter at the FGCZ!
I am also looking forward to my next chapter at the FGCZ!
Reposted by David Taborsky
Our latest monthly #preprint list is out!
Have a look at the #DevBio and stem cell biology preprints that came out in July. Congrats to all authors 🎉
thenode.biologists.com/july-in-prep...
Have a look at the #DevBio and stem cell biology preprints that came out in July. Congrats to all authors 🎉
thenode.biologists.com/july-in-prep...
July in preprints - the Node
Welcome to our monthly trawl for developmental and stem cell biology (and related) preprints. The preprints this month are hosted on bioRxiv.
thenode.biologists.com
August 12, 2025 at 1:35 PM
Our latest monthly #preprint list is out!
Have a look at the #DevBio and stem cell biology preprints that came out in July. Congrats to all authors 🎉
thenode.biologists.com/july-in-prep...
Have a look at the #DevBio and stem cell biology preprints that came out in July. Congrats to all authors 🎉
thenode.biologists.com/july-in-prep...
If you are interested in #DevBio, #organoids, #gastruloids or #CRISPR, check out the tweetorial to our new preprint on uncovering novel regulators of body plan formation in gastruloids using single cell CRISPR screens!
A big thank you to all co-authors that made this paper possible!
A big thank you to all co-authors that made this paper possible!
The establishment of the body plan during gastrulation is a hallmark of animal life, yet much of its regulation remains unclear. Here, we combine gastruloids and single-cell CRISPR screenings to uncover new regulators of the body plan.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
August 6, 2025 at 4:47 PM
If you are interested in #DevBio, #organoids, #gastruloids or #CRISPR, check out the tweetorial to our new preprint on uncovering novel regulators of body plan formation in gastruloids using single cell CRISPR screens!
A big thank you to all co-authors that made this paper possible!
A big thank you to all co-authors that made this paper possible!
How can we identify novel regulators of germ layer differentiation and body patterning? I am happy to announce that my preprint using single-cell CRISPR screens in gastruloids to answer this question is now online! Thank you to the rest of the @sendoellab.bsky.social and all coauthors!
Regulation of mRNA polyadenylation governs mammalian body plan formation in gastruloids https://www.biorxiv.org/content/10.1101/2025.07.22.666114v1
July 25, 2025 at 2:59 PM
How can we identify novel regulators of germ layer differentiation and body patterning? I am happy to announce that my preprint using single-cell CRISPR screens in gastruloids to answer this question is now online! Thank you to the rest of the @sendoellab.bsky.social and all coauthors!
Check out this cool new preprint from our lab! Congratulations to @merveyigit.bsky.social, the hard work paid off! 🥳
Identified in the 1970s, the precise molecular function of the alternative initiation factor eIF2A has remained unclear. Here, we map its interactome and uncover a surprising role in ribosome-associated quality control (RQC) upon ribosome stalling. 1/x
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
The alternative initiation factor eIF2A regulates 40S subunit turnover in ribosome-associated quality control
The noncanonical translation initiation factor eIF2A plays critical roles in diverse cellular processes, including the integrated stress response, neurodegeneration and tumorigenesis. However, the pre...
www.biorxiv.org
May 28, 2025 at 6:06 AM
Check out this cool new preprint from our lab! Congratulations to @merveyigit.bsky.social, the hard work paid off! 🥳
Reposted by David Taborsky
Our genome encodes > 7000 microproteins that have been previously ignored in genome annotations. How do these microproteins impact tissue function? Here, we use an in vivo single-cell CRISPR screen to systematically explore microprotein function in the mouse epidermis. 1/9
www.biorxiv.org
March 19, 2025 at 3:44 PM
Our genome encodes > 7000 microproteins that have been previously ignored in genome annotations. How do these microproteins impact tissue function? Here, we use an in vivo single-cell CRISPR screen to systematically explore microprotein function in the mouse epidermis. 1/9
Reposted by David Taborsky
I'm thrilled to share the latest pre-print from our lab. An in vivo single-cell ribosome profiling study investigating the translational landscape of aging skin.
#aging #single-cell #Ribo-sea
#aging #single-cell #Ribo-sea
How does aging alter the translational landscape of stem cells and how do these changes impact their regenerative capacity? Here we developed an in vivo single-cell ribosome profiling strategy to monitor translational landscapes of the mouse epidermis 1/6
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 19, 2024 at 11:41 AM
I'm thrilled to share the latest pre-print from our lab. An in vivo single-cell ribosome profiling study investigating the translational landscape of aging skin.
#aging #single-cell #Ribo-sea
#aging #single-cell #Ribo-sea