Clémence Marchal
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clemmar.bsky.social
Clémence Marchal
@clemmar.bsky.social
490 followers 570 following 30 posts
Postdoc in the @geminiteamlab.bsky.social ZMBP, Uni Tübingen
Plant - Microbe Interactions 🌱🦠🍄
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clemmar.bsky.social
Clémence Marchal @clemmar.bsky.social · Dec 3
Excited to share our latest work on plant immune receptor biochemistry! @kamounlab.bsky.social @hsuanpai.bsky.social @mpcontreras.bsky.social Jose Salguero Linares @danielluedke.bsky.social @adnroide.bsky.social @jiorgoskourelis.bsky.social

www.biorxiv.org/content/10.6...
CC-NLRs exhibit diverse conformations in the resting state. Figure depicts different NLR resting and activated states. While ZAR1 exists as a monomer bound to its guardees in its resting state, several forms have been observed for the NRC2 helper, including dimers, tetramers, and filaments. While filament-like structures were observed via confocal microscopy for NRC2 upon overexpression in planta, these structures were not detected for its paralog NRC4, suggesting a potentially different resting state configuration for NRC4. Our work suggests that the Pik CC-NLR pair forms a hetero-complex bound to the plasma membrane in its resting state. How effector binding to the integrated domain (ID) of the Pik-1 sensor leads to the activation of the complex remains to be determined.
Reposted by Clémence Marchal
delaconcepcionjc.bsky.social
With the new year, is my time to say bye to @gmivienna.bsky.social as I move to @zmbp-tuebingen.bsky.social in Tuebingen. I will start my solo Group Leader career as a Emmy Norther fellow. Thanks to everyone that helped on the way. I will be advertising PhD and Postdoc positions soon, stay tuned!
January 11, 2026 at 1:04 PM
Reposted by Clémence Marchal
thevirusmc.bsky.social
The Clavel Group is recruiting a new postdoc for two possible projects dealing with plant-virus interactions and selective autophagy! More (wordy) details below ⬇️🌱🦠
December 16, 2025 at 5:15 PM
Reposted by Clémence Marchal
durocyann.bsky.social
Un peu de lecture à partager un max parce que le traitement de l’actualité c’est toujours pas ça

Les NGT font partie d’un continuum qui a commencé avec la mutagenèse aléatoire induite (mais avec une précision inédite)

creationvarietale.wordpress.com/2024/12/04/c...
Comment la mutagenèse aléatoire induite a changé la donne au 20e siècle
Article issu du #QuizAmeliorationDesPlantes n°12 Première Publication 30 mai 2020 La mutagenèse aléatoire induite a profondément et durablement impacté les programmes de sélection depuis les années…
creationvarietale.wordpress.com
December 4, 2025 at 9:54 PM
Reposted by Clémence Marchal
greenrobust.de
European Council and Parliament agree on relaxing rules for bringing genome-edited plants to the market - a central step for facilitating a science-based management of our current plant systems.
www.consilium.europa.eu/en/press/pre...
New genomic techniques: Council and Parliament strike deal to boost the competitiveness and sustainability of our food systems
Council and Parliament reach provisional deal on a set of rules for new genomic techniques, aiming to improve the competitiveness of European agriculture and support the sustainability of our food sys...
www.consilium.europa.eu
December 4, 2025 at 8:21 AM
Reposted by Clémence Marchal
kamounlab.bsky.social
I just published: On the diversity of resting states of NLR immune receptors

New story on rice Pik NLR immune receptor pair — turns out it sits as a 1 MDa membrane-bound beast before activation 🤯. Another wild twist in the ever-expanding universe of NLR resting states!

medium.com/p/on-the-div...
On the diversity of resting states of NLR immune receptors
New story on the rice Pik NLR immune receptor pair — turns out it sits as a 1 MDa membrane-bound beast before activation 🤯. Another wild…
medium.com
December 4, 2025 at 11:51 AM
Reposted by Clémence Marchal
plantepigenetics.ch
Finally! The European Union allows the use of genome editing! 🌱🌾🫛🇪🇺🧬

www.tagesschau.de/wirtschaft/v...
EU einigt sich auf Lockerungen für gentechnisch veränderte Lebensmittel
Für viele gentechnisch veränderte Lebensmittel soll es künftig keine Hinweispflicht mehr in Supermärkten geben. Darauf einigten sich Vertreter aus dem Europaparlament und dem Rat der EU-Länder.
www.tagesschau.de
December 4, 2025 at 4:17 AM
Reposted by Clémence Marchal
biorxiv-plants.bsky.social
The Pik NLR pair accumulates at the plasma membrane as a hetero-oligomeric sensor-helper immune protein complex prior to activation https://www.biorxiv.org/content/10.64898/2025.11.30.691369v1
December 2, 2025 at 10:01 PM
Reposted by Clémence Marchal
natmethods.nature.com
Helixer: a tool for ab initio gene annotation with broad taxonomic coverage. @usadellab.bsky.social @apmweber.bsky.social @weberlab.bsky.social

www.nature.com/articles/s41...
Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model - Nature Methods
By leveraging both deep learning and hidden Markov models, Helixer achieves broad taxonomic coverage for ab initio gene annotation of eukaryotic genomes from fungi, plants, vertebrates and invertebrat...
www.nature.com
December 3, 2025 at 5:35 PM
Reposted by Clémence Marchal
somssich.bsky.social
We are looking for a Head of Cell Biology here at @kwsgroup.bsky.social Vegetables.

This is a permanent, full-time position located in Wageningen, Netherlands.

jobs.kws.com/job/Wagening...

#PlantScience #PlantSciJobs #PlantScienceJobs #PlantCellBiology #PlantBreeding #PlantSciJob #PlantScienceJob
Head of Cell Biology KWS Vegetables
Head of Cell Biology KWS Vegetables
jobs.kws.com
December 1, 2025 at 1:36 PM
Reposted by Clémence Marchal
mpcontreras.bsky.social
Check out our new story on the famous rice Pik NLR pair, led by @clemmar.bsky.social and @hsuanpai.bsky.social! Turns out they form a massive 1 MDa membrane-associated complex before activation 🤯
A cool new example of the diversity of NLR resting states!
December 3, 2025 at 2:52 PM
Reposted by Clémence Marchal
jamesbriscoe.bsky.social
Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:

Mentoring
Profile raising
Leadership training
Network building

Spread the word...

www.biologists.com/grants/devel...
Development's Pathway to Independence Programme
Our grants support and encourage the sharing of knowledge throughout the community by facilitating international collaboration, event attendance and the organisation of scientific meetings, conference...
www.biologists.com
December 3, 2025 at 6:56 AM
clemmar.bsky.social
Excited to share our latest work on plant immune receptor biochemistry! @kamounlab.bsky.social @hsuanpai.bsky.social @mpcontreras.bsky.social Jose Salguero Linares @danielluedke.bsky.social @adnroide.bsky.social @jiorgoskourelis.bsky.social

www.biorxiv.org/content/10.6...
CC-NLRs exhibit diverse conformations in the resting state. Figure depicts different NLR resting and activated states. While ZAR1 exists as a monomer bound to its guardees in its resting state, several forms have been observed for the NRC2 helper, including dimers, tetramers, and filaments. While filament-like structures were observed via confocal microscopy for NRC2 upon overexpression in planta, these structures were not detected for its paralog NRC4, suggesting a potentially different resting state configuration for NRC4. Our work suggests that the Pik CC-NLR pair forms a hetero-complex bound to the plasma membrane in its resting state. How effector binding to the integrated domain (ID) of the Pik-1 sensor leads to the activation of the complex remains to be determined.
December 3, 2025 at 9:20 AM
Reposted by Clémence Marchal
incavirus.bsky.social
Preprint alert! It is my great pleasure to announce the first manuscript from the lab, a story that started @gmivienna.bsky.social and was mainly accomplished by the intrepid @gesahoffmann.bsky.social at @mpi-mp-potsdam.bsky.social. A brief thread with our findings
www.biorxiv.org/content/10.1...
AGO5 restricts virus vertical transmission in plant gametophytes
The propagation of a viral infection from a host parent to its progeny is known as vertical transmission, or seed transmission in plants. It allows viral infections to rapidly spread locally via polle...
www.biorxiv.org
December 2, 2025 at 12:34 PM
Reposted by Clémence Marchal
plantophagy.bsky.social
Glad to have this finally published: www.sciencedirect.com/science/arti... lots of new data since the #preprint. If you are into selective #autophagy, #evolution, #proteostasis Please have a look!
December 1, 2025 at 5:44 PM
Reposted by Clémence Marchal
geminiteamlab.bsky.social
The GT goes to Stuttgart! A (brief) trip, nice scenery, good food, a touch of (mostly fictitious) science, and excellent company! What else could one wish for in a lab retreat? (Ah — it was also the 10th anniversary of the lab!) 🎂🌱🦠
November 27, 2025 at 6:37 PM
Reposted by Clémence Marchal
thesainsburylab.bsky.social
Ever wondered what it's like to work in research support at TSL?

To find out, we asked Dr @adelineharant.bsky.social, Senior Research Assistant in the @kamounlab.bsky.social, who told us about her career and her passions in and outside the lab.

Read the full interview here: buff.ly/e6gGB7j
A photo of Dr Adeline Harant, Senior Research Assistant in the Kamoun Group at TSL, sitting in front of her laptop. A quote from the interview reads "My day can be quite different depending on what I have to do. No two days are the same, anything can happen."
November 20, 2025 at 5:04 PM
Reposted by Clémence Marchal
berasymbionts.bsky.social
Super excited to be joining @thesainsburylab.bsky.social and to begin this new chapter in Norwich!!
And thrilled to be neighbours with the Mutualisms Research Group at @hassansalem.bsky.social and the wider community at @johninnescentre.bsky.social. Can’t wait to get started! 😁
Calm river in Norwich with reflections of riverside houses on the water under a clear sky.
November 24, 2025 at 2:08 PM
Reposted by Clémence Marchal
johninnescentre.bsky.social
PRESS RELEASE – Dr Hassan Salem to lead independent research group on plant-insect interactions

Following an international search, we are delighted to announce that Dr Hassan Salem @hassansalem.bsky.social will be joining us in early 2026: www.jic.ac.uk/press-releas...
Dr Hassan Salem
November 24, 2025 at 4:11 PM
Reposted by Clémence Marchal
philcarella.bsky.social
New opportunity to undertake a PhD in my group ⁦‪at the John Innes Centre - if you’re interested in plant immunity and evolution check out the link!
Understanding Host Compatibility in the Marchantia-Phytophthora System (CARELLA_J26DTP) | Doctoral Training Partnership
The fossil record demonstrates that filamentous microbes invaded ancient plant cells with intracellular hyphal structures over 450 million years ago. To this day, a rich diversity of extant land plant...
biodtp.norwichresearchpark.ac.uk
October 12, 2025 at 5:30 PM
Reposted by Clémence Marchal
gittacoaker.bsky.social
FRET sensor for SA developed. www.science.org/doi/10.1126/...
SALICYLIC ACID SENSOR1 reveals the propagation of an SA hormone surge during plant pathogen advance
Salicylic acid (SA) is a key phytohormone that orchestrates immune responses against pathogens, including Pseudomonas syringae bacteria. The timing and extent of SA accumulation are tightly controlled...
www.science.org
October 9, 2025 at 9:11 PM
Reposted by Clémence Marchal
jacquet-chris.bsky.social
Want to see ferns under attack and how they respond to pathogens? Check out our latest paper!
doi.org/10.1186/s129...
Congrats on this huge team effort to @baptistebio.bsky.social @madeleinebaker.bsky.social @kellerjeanphd.bsky.social @maximebonhomme.bsky.social @pierremarcdelaux.bsky.social
Various ferns species inoculated with S. sclerotiorum.
October 9, 2025 at 3:40 PM
Reposted by Clémence Marchal
geminiteamlab.bsky.social
How do geminiviruses maximize their limited coding capacity? Our recent preprint uncovers splicing of viral transcripts as one more strategy used by this viral family. We show that RNA splicing is prevalent in the geminivirus TYLCV — and required for infectivity! www.biorxiv.org/content/10.1...
Pervasive splicing in a plant DNA virus
Viruses maximize their limited coding space through strategies that increase transcript and protein diversity. In mammalian viruses, splicing is a well-established mechanism for proteome expansion, ye...
www.biorxiv.org
October 3, 2025 at 1:13 PM
Reposted by Clémence Marchal
delphinem-p.bsky.social
Splicing was discovered in adenoviruses, but was thought to be only anecdotal in plant viruses... We may need to revisit plant viral transcriptomes and proteomes!
geminiteamlab.bsky.social GeminiTeamLab @geminiteamlab.bsky.social · Oct 3
How do geminiviruses maximize their limited coding capacity? Our recent preprint uncovers splicing of viral transcripts as one more strategy used by this viral family. We show that RNA splicing is prevalent in the geminivirus TYLCV — and required for infectivity! www.biorxiv.org/content/10.1...
Pervasive splicing in a plant DNA virus
Viruses maximize their limited coding space through strategies that increase transcript and protein diversity. In mammalian viruses, splicing is a well-established mechanism for proteome expansion, ye...
www.biorxiv.org
October 3, 2025 at 8:57 PM
Reposted by Clémence Marchal
geminiteamlab.bsky.social
Incredibly happy and proud of our Chaonan Shi (chaonan123.bsky.social ), who successfully defended her doctoral thesis yesterday at the @zmbp-tuebingen.bsky.social ! (And what a brilliant defence it was!) 🥳🥳🥳 Congratulations, Dr Shi!!! 🍾🥂🍋‍🟩🌶️ We are so lucky to have you in our team ❤️
October 3, 2025 at 9:34 AM
Reposted by Clémence Marchal
yichangsung.bsky.social
Our review on disease resistance gene diversity in Triticeae is finally online 🌾🌾! Gained so many insights writing it with Yinghui Li & Liubov Govta and from the guidance of gittacoaker.bsky.social & Tzion Fahima. Fascinated by plant resistance gene diversity—excited to share!
September 17, 2025 at 1:14 AM