Jan Claesen
@claesengroup.bsky.social
Associate Professor at Lerner Research Institute, Cleveland Clinic.
Lover of bacteria in isolation and in communities.
Dissecting the human microbiome on a molecular level.
🇧🇪🇺🇸 Father of two. Views are my own.
https://claesengroup.org/
Lover of bacteria in isolation and in communities.
Dissecting the human microbiome on a molecular level.
🇧🇪🇺🇸 Father of two. Views are my own.
https://claesengroup.org/
Pinned
Jan Claesen
@claesengroup.bsky.social
· Oct 19
Hi everyone, I tried assembling a Microbiome & friends starter pack.
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Still learning to use bluesky and might have missed you, let me know if you would like to be included.
go.bsky.app/Fq36egy
🦠🧫🔬
Still learning to use bluesky and might have missed you, let me know if you would like to be included.
go.bsky.app/Fq36egy
Ruin a book with a car:
Ford of the rings
Ford of the rings
Ruin a book with a car:
The Old Man and the C-Class
The Old Man and the C-Class
September 25, 2025 at 11:43 AM
Ruin a book with a car:
Ford of the rings
Ford of the rings
Reposted by Jan Claesen
Music FACT: Placebo were originally a Cure tribute band
September 19, 2025 at 8:15 AM
Music FACT: Placebo were originally a Cure tribute band
She's a real hero!
💪👇
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Gabrielle Wall sets the Guinness World Record for fastest 100M on LEGO at 24.75 seconds! 😂🤕
(🎥: Guinness World Records)
(🎥: Guinness World Records)
September 8, 2025 at 6:20 PM
She's a real hero!
💪👇
💪👇
Reposted by Jan Claesen
✨ Exciting News ✨I am thrilled to share that I have accepted a position as an Assistant Professor in the Department of Infectious Diseases and Microbiology (IDM), at the University of Pittsburgh School of Public Health!
September 3, 2025 at 3:48 PM
✨ Exciting News ✨I am thrilled to share that I have accepted a position as an Assistant Professor in the Department of Infectious Diseases and Microbiology (IDM), at the University of Pittsburgh School of Public Health!
Slightly diminish a band:
The green mild bell peppers
The green mild bell peppers
Slightly diminish a band: Bronze Maiden
Slightly diminish a band: Twenty Pilots
August 13, 2025 at 3:54 AM
Slightly diminish a band:
The green mild bell peppers
The green mild bell peppers
Reposted by Jan Claesen
Conferencing with my favorite natural product chemist this week at the #ASP2025 in Grands Rapids, Michigan. Great science, inspiring talks, and reconnecting with friends and colleagues! @claesengroup.bsky.social @eustaquiolab.bsky.social @balunaslab.bsky.social #SecMet #NaturalProducts
August 7, 2025 at 12:49 PM
Conferencing with my favorite natural product chemist this week at the #ASP2025 in Grands Rapids, Michigan. Great science, inspiring talks, and reconnecting with friends and colleagues! @claesengroup.bsky.social @eustaquiolab.bsky.social @balunaslab.bsky.social #SecMet #NaturalProducts
Potato, potahto, tomato, tomahto
Let's call the whole thing off 🎶🎶
www.theguardian.com/science/2025...
Let's call the whole thing off 🎶🎶
www.theguardian.com/science/2025...
‘This wasn’t obvious’: the potato evolved from a tomato ancestor, researchers find
Hybridisation event took place about 9 million years ago, helping to ‘spark the emergence of a new organ’
www.theguardian.com
August 4, 2025 at 2:25 PM
Potato, potahto, tomato, tomahto
Let's call the whole thing off 🎶🎶
www.theguardian.com/science/2025...
Let's call the whole thing off 🎶🎶
www.theguardian.com/science/2025...
Reposted by Jan Claesen
Check out the Ziemert Lab’s new YouTube channel
m.youtube.com/@ZiemertLab
We’ve uploaded short tutorial videos on how to use our tools for genome mining and natural product discovery.
Thanks Semih, @martinaadamek.bsky.social @turgutmesut.bsky.social ! #GenomeMining #SecMet #naturalproducts
m.youtube.com/@ZiemertLab
We’ve uploaded short tutorial videos on how to use our tools for genome mining and natural product discovery.
Thanks Semih, @martinaadamek.bsky.social @turgutmesut.bsky.social ! #GenomeMining #SecMet #naturalproducts
ZiemertLab
The Ziemert lab is interested in the evolution and distribution of bacterial secondary metabolites. These bioactive compounds are especially important in human medicine as the chemical scaffolds are t...
m.youtube.com
July 8, 2025 at 8:09 PM
Check out the Ziemert Lab’s new YouTube channel
m.youtube.com/@ZiemertLab
We’ve uploaded short tutorial videos on how to use our tools for genome mining and natural product discovery.
Thanks Semih, @martinaadamek.bsky.social @turgutmesut.bsky.social ! #GenomeMining #SecMet #naturalproducts
m.youtube.com/@ZiemertLab
We’ve uploaded short tutorial videos on how to use our tools for genome mining and natural product discovery.
Thanks Semih, @martinaadamek.bsky.social @turgutmesut.bsky.social ! #GenomeMining #SecMet #naturalproducts
Reposted by Jan Claesen
NASA is more than rockets and moonwalks. NASA is behind much of our everyday technology. From space discovery, to Air Jordans, to CAT scans, NASA has played a role. We get it all on less than a penny of every federal dollar. Now their science may be gutted by 50%.
#NASADidThat
#NASADidThat
July 10, 2025 at 10:39 PM
NASA is more than rockets and moonwalks. NASA is behind much of our everyday technology. From space discovery, to Air Jordans, to CAT scans, NASA has played a role. We get it all on less than a penny of every federal dollar. Now their science may be gutted by 50%.
#NASADidThat
#NASADidThat
Reposted by Jan Claesen
🎉 Congratulations to Djenet Bousbaine, winner of the 2025 NOSTER & Science Microbiome Prize for her work to illuminate how the immune system responds to the beneficial skin microbiome.
Learn more: scim.ag/4lVwpFx
Learn more: scim.ag/4lVwpFx
July 4, 2025 at 2:07 PM
🎉 Congratulations to Djenet Bousbaine, winner of the 2025 NOSTER & Science Microbiome Prize for her work to illuminate how the immune system responds to the beneficial skin microbiome.
Learn more: scim.ag/4lVwpFx
Learn more: scim.ag/4lVwpFx
Reposted by Jan Claesen
The new open access policy of NIH will take effect next week (July 1st). All NIH funded research 🔬🧪🧬accepted after July 1st must be open access upon publication. Worried about fees? 💸 Check out how IAI stacks up against other journals—you might be surprised. #OpenAccess #SciComm #Microbiology
June 26, 2025 at 9:47 PM
The new open access policy of NIH will take effect next week (July 1st). All NIH funded research 🔬🧪🧬accepted after July 1st must be open access upon publication. Worried about fees? 💸 Check out how IAI stacks up against other journals—you might be surprised. #OpenAccess #SciComm #Microbiology
When all this pollution is causing you headaches...
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Paracetemol from plastic waste www.nature.com/articles/s41...
A biocompatible Lossen rearrangement in Escherichia coli - Nature Chemistry
Biocompatible chemistry merges chemo-catalytic reactions with cellular metabolism for sustainable small-molecule synthesis. Now a biocompatible Lossen rearrangement has been demonstrated to control ba...
www.nature.com
June 24, 2025 at 11:26 AM
When all this pollution is causing you headaches...
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Reposted by Jan Claesen
Reposted by Jan Claesen
Interested in microbiome GWAS and heritability studies? Check out our new Review in Nature Reviews Genetics! We explore key findings, challenges, and future directions of the field.
rdcu.be/epoRR
@blekhman.bsky.social @sambhawa.bsky.social and Dr. Kelsey Johnson.
rdcu.be/epoRR
@blekhman.bsky.social @sambhawa.bsky.social and Dr. Kelsey Johnson.
Genomics of host–microbiome interactions in humans
Nature Reviews Genetics - In this Review, Ferretti et al. discuss advances in our understanding of interactions between the human genome and the microbiome, including the effects of the microbiome...
rdcu.be
June 4, 2025 at 4:52 PM
Interested in microbiome GWAS and heritability studies? Check out our new Review in Nature Reviews Genetics! We explore key findings, challenges, and future directions of the field.
rdcu.be/epoRR
@blekhman.bsky.social @sambhawa.bsky.social and Dr. Kelsey Johnson.
rdcu.be/epoRR
@blekhman.bsky.social @sambhawa.bsky.social and Dr. Kelsey Johnson.
Reposted by Jan Claesen
🥁NEW publication from our lab:
the largest meta-analysis of gut microbiome associations with CRC!
www.nature.com/articles/s41...
🧵⬇️
1/6
the largest meta-analysis of gut microbiome associations with CRC!
www.nature.com/articles/s41...
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1/6
Pooled analysis of 3,741 stool metagenomes from 18 cohorts for cross-stage and strain-level reproducible microbial biomarkers of colorectal cancer - Nature Medicine
An analysis of 18 metagenomic datasets of individuals with colorectal cancer, adenomas and healthy controls yields improved cancer prediction accuracy based solely on gut metagenomics, as well as the ...
www.nature.com
June 3, 2025 at 10:43 AM
🥁NEW publication from our lab:
the largest meta-analysis of gut microbiome associations with CRC!
www.nature.com/articles/s41...
🧵⬇️
1/6
the largest meta-analysis of gut microbiome associations with CRC!
www.nature.com/articles/s41...
🧵⬇️
1/6
Reposted by Jan Claesen
Opening for a #postdoc in the lab available immediately. Please spread the word.
DETAILS HERE: jobrxiv.org/job/baylor-c...
cc: #academicJobs #postdocJobs #microbiome #Celegans #organoids #IBD #PathSky #Medsky #AcademicSky 🧪 🧬 🦠
DETAILS HERE: jobrxiv.org/job/baylor-c...
cc: #academicJobs #postdocJobs #microbiome #Celegans #organoids #IBD #PathSky #Medsky #AcademicSky 🧪 🧬 🦠
Postdoctoral Associate in IBD genetics in C. elegans and organoids
Post a job in 3min, or find thousands of job offers like this one at jobRxiv!
jobrxiv.org
May 31, 2025 at 4:28 PM
Opening for a #postdoc in the lab available immediately. Please spread the word.
DETAILS HERE: jobrxiv.org/job/baylor-c...
cc: #academicJobs #postdocJobs #microbiome #Celegans #organoids #IBD #PathSky #Medsky #AcademicSky 🧪 🧬 🦠
DETAILS HERE: jobrxiv.org/job/baylor-c...
cc: #academicJobs #postdocJobs #microbiome #Celegans #organoids #IBD #PathSky #Medsky #AcademicSky 🧪 🧬 🦠
Reposted by Jan Claesen
'If successful, it would be the first new class of antibiotic capable of killing acinetobacter or any other “Gram-negative” bacteria to be developed for more than 50 years. This type of bug has a structure that makes it more difficult to treat.'
www.ft.com/content/1f94...
www.ft.com/content/1f94...
Roche extends trials of promising antibiotic against resistant superbug
If successful, it would be the first new class of drug against certain bacteria strains for more than 50 years
www.ft.com
May 26, 2025 at 9:45 AM
'If successful, it would be the first new class of antibiotic capable of killing acinetobacter or any other “Gram-negative” bacteria to be developed for more than 50 years. This type of bug has a structure that makes it more difficult to treat.'
www.ft.com/content/1f94...
www.ft.com/content/1f94...
I'm delighted to share the preprint on Layan's investigation into the effect of nisin Z on intestinal tumor formation! 🎉 🎉🎉
May 20, 2025 at 12:31 PM
I'm delighted to share the preprint on Layan's investigation into the effect of nisin Z on intestinal tumor formation! 🎉 🎉🎉
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Excited to share Sara's work on the importance of gut microbial metabolism of dietary polyphenols in preventing obesity and prediabetes associated disorders!
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Check out her preprint here:
(1/5)
Excited to share Sara's work on the importance of gut microbial metabolism of dietary polyphenols in preventing obesity and prediabetes associated disorders!
🚨🚨🚨
Check out her preprint here:
(1/5)
May 19, 2025 at 8:58 AM
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Excited to share Sara's work on the importance of gut microbial metabolism of dietary polyphenols in preventing obesity and prediabetes associated disorders!
🚨🚨🚨
Check out her preprint here:
(1/5)
Excited to share Sara's work on the importance of gut microbial metabolism of dietary polyphenols in preventing obesity and prediabetes associated disorders!
🚨🚨🚨
Check out her preprint here:
(1/5)
Reposted by Jan Claesen
PLEASE SHARE We’re hiring a contract #bioinformatician (research officer) to analyse #microbiome data from an ongoing, exciting project focusing on preterm birth prevention with oral probiotics
topjobs-teagasc.thehirelab.com/LiveJobs/Job...
topjobs-teagasc.thehirelab.com/LiveJobs/Job...
May 12, 2025 at 10:12 AM
PLEASE SHARE We’re hiring a contract #bioinformatician (research officer) to analyse #microbiome data from an ongoing, exciting project focusing on preterm birth prevention with oral probiotics
topjobs-teagasc.thehirelab.com/LiveJobs/Job...
topjobs-teagasc.thehirelab.com/LiveJobs/Job...
Reposted by Jan Claesen
Hey y'all! My department is conducting a search for an assistant or associate professor in bacteriology. It's pretty broadly defined. If you know anyone who's looking for a great department that does awesome science - please send them our way! You can DM me with any questions you have 😀
May 9, 2025 at 7:22 PM
Hey y'all! My department is conducting a search for an assistant or associate professor in bacteriology. It's pretty broadly defined. If you know anyone who's looking for a great department that does awesome science - please send them our way! You can DM me with any questions you have 😀
Reposted by Jan Claesen
Delighted to announce the @keystonesymposia.bsky.social meeting: Beyond #Antibiotics: Emerging Strategies Combating #BacterialInfection. Join us in Breckenridge in May 2026!!
You can check out the program and amazing lineup of speakers below: keysym.us/KSAntibiotics26
#KSAntibiotics26
You can check out the program and amazing lineup of speakers below: keysym.us/KSAntibiotics26
#KSAntibiotics26
Beyond Antibiotics: Emerging Strategies for Combating Bacterial Infection | Keystone Symposia
Join us at the Keystone Symposia on Beyond Antibiotics: Emerging Strategies for Combating Bacterial Infection, May 2026, in Breckenridge, with field leaders!
keysym.us
May 9, 2025 at 12:25 PM
Delighted to announce the @keystonesymposia.bsky.social meeting: Beyond #Antibiotics: Emerging Strategies Combating #BacterialInfection. Join us in Breckenridge in May 2026!!
You can check out the program and amazing lineup of speakers below: keysym.us/KSAntibiotics26
#KSAntibiotics26
You can check out the program and amazing lineup of speakers below: keysym.us/KSAntibiotics26
#KSAntibiotics26
Reposted by Jan Claesen
I reviewed a paper recently. It was flawed & rejected. It later appeared unchanged in another journal.
So how is peer review a “gold standard”?
You can’t have a gold standard if people can’t tell the difference between gold and bauxite..
So how is peer review a “gold standard”?
You can’t have a gold standard if people can’t tell the difference between gold and bauxite..
April 28, 2025 at 11:34 AM
I reviewed a paper recently. It was flawed & rejected. It later appeared unchanged in another journal.
So how is peer review a “gold standard”?
You can’t have a gold standard if people can’t tell the difference between gold and bauxite..
So how is peer review a “gold standard”?
You can’t have a gold standard if people can’t tell the difference between gold and bauxite..
Reposted by Jan Claesen
If you are interested in lipids in bacteria, check out this awesome new review written by my talented student Alyssa Carter, super postdoc Emily Woods and me. #chembio
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Chemical strategies for targeting lipid pathways in bacterial pathogens
Microbial pathogens continue to plague human health and develop resistance to our current frontline treatments. Over the last few decades, there has b…
www.sciencedirect.com
April 19, 2025 at 10:22 PM
If you are interested in lipids in bacteria, check out this awesome new review written by my talented student Alyssa Carter, super postdoc Emily Woods and me. #chembio
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Jan Claesen
🧵 The ATCC Genome Portal hit 5,500 authenticated microbial genomes (>2,600 species)! 🎉🥳 We've sequenced, assembled, annotated 4,538 bacteria, 479 viruses, 479 fungi, and 4 protists! All NGS in-house @ ATCC under ISO, and >90% on BOTH @nanoporetech.com and #Illumina 😎 www.atcc.org/applications...
Discover the ATCC Genome Portal | ATCCCart
www.atcc.org
April 2, 2025 at 7:23 PM
🧵 The ATCC Genome Portal hit 5,500 authenticated microbial genomes (>2,600 species)! 🎉🥳 We've sequenced, assembled, annotated 4,538 bacteria, 479 viruses, 479 fungi, and 4 protists! All NGS in-house @ ATCC under ISO, and >90% on BOTH @nanoporetech.com and #Illumina 😎 www.atcc.org/applications...