Chiara Stringari
@chiarastringari.bsky.social
Scientist at @cnrs.bsky.social @laboptbio.bsky.social
https://lob.ip-paris.fr/chiara-stringari
Label-free optical microscopy and metabolic imaging.
'Science doesn't care about what you believe'
https://lob.ip-paris.fr/chiara-stringari
Label-free optical microscopy and metabolic imaging.
'Science doesn't care about what you believe'
A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular l-lactate dynamics
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular l-lactate dynamics - Nature Communications
l-lactate is a key metabolite supporting neuronal activity, but methods to monitor l-lactate dynamics alongside neuronal activity in vivo have been limited. Here, authors report R-eLACCO2.1, a red flu...
www.nature.com
October 31, 2025 at 8:18 AM
A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular l-lactate dynamics
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Chiara Stringari
Wrapping up #Mifobio2025!
What I love most about this conference is how it reminds me that science is, above all, a collaborative effort. Nothing beats the sense of community here. See you in 2 years!
Check the Imabio @gdrimabio.bsky.social website for course and seminar replays soon imabio-cnrs.fr
What I love most about this conference is how it reminds me that science is, above all, a collaborative effort. Nothing beats the sense of community here. See you in 2 years!
Check the Imabio @gdrimabio.bsky.social website for course and seminar replays soon imabio-cnrs.fr
October 22, 2025 at 6:55 PM
Wrapping up #Mifobio2025!
What I love most about this conference is how it reminds me that science is, above all, a collaborative effort. Nothing beats the sense of community here. See you in 2 years!
Check the Imabio @gdrimabio.bsky.social website for course and seminar replays soon imabio-cnrs.fr
What I love most about this conference is how it reminds me that science is, above all, a collaborative effort. Nothing beats the sense of community here. See you in 2 years!
Check the Imabio @gdrimabio.bsky.social website for course and seminar replays soon imabio-cnrs.fr
Here you can find the slides of the MIFOBIO 2025 Workshop "A-07 Analyzing FLIM data for metabolic imaging applications with Phasor Analysis" using FLUTE software, with Xiaotong Yuan.
zenodo.org/records/1736...
#mifobio2025
zenodo.org/records/1736...
#mifobio2025
October 16, 2025 at 8:18 AM
Here you can find the slides of the MIFOBIO 2025 Workshop "A-07 Analyzing FLIM data for metabolic imaging applications with Phasor Analysis" using FLUTE software, with Xiaotong Yuan.
zenodo.org/records/1736...
#mifobio2025
zenodo.org/records/1736...
#mifobio2025
Amazing talk on “Mechanobiology of the Mitotic Spindle” by @ivatolic.bsky.social at #mifobio2025 @gdrimabio.bsky.social
October 15, 2025 at 8:44 PM
Amazing talk on “Mechanobiology of the Mitotic Spindle” by @ivatolic.bsky.social at #mifobio2025 @gdrimabio.bsky.social
Reposted by Chiara Stringari
(2025/10/08) Congratulations to @chiarastringari.bsky.social on the defense of her Habilitation à Diriger les Recherches (HDR) "Label-free multimodal non-linear optical microscopy for functional imaging of living tissues" !
October 9, 2025 at 9:50 AM
(2025/10/08) Congratulations to @chiarastringari.bsky.social on the defense of her Habilitation à Diriger les Recherches (HDR) "Label-free multimodal non-linear optical microscopy for functional imaging of living tissues" !
Over a decade at @laboptbio.bsky.social at @polytechniqueparis.bsky.social !
September 3, 2025 at 11:58 AM
Over a decade at @laboptbio.bsky.social at @polytechniqueparis.bsky.social !
Reposted by Chiara Stringari
Happy to finally publish this work… Congrats authors and thanks funders @agencerecherche.bsky.social #FondationBettencourtSchueller
July 16, 2025 at 1:39 PM
Happy to finally publish this work… Congrats authors and thanks funders @agencerecherche.bsky.social #FondationBettencourtSchueller
Reposted by Chiara Stringari
These findings help to establish THG microscopy as a quantitative, multiscale imaging technique, paving the way for new applications. 📖 #Neuroscience #Myelin #THG #Microscopy #Research
July 16, 2025 at 1:39 PM
These findings help to establish THG microscopy as a quantitative, multiscale imaging technique, paving the way for new applications. 📖 #Neuroscience #Myelin #THG #Microscopy #Research
Reposted by Chiara Stringari
Fun fact for multiphoton microscopy geeks: aberrations caused by vertical micro-interfaces appear to be a significant contrast mechanism in polarized THG imaging. 😎
July 16, 2025 at 1:39 PM
Fun fact for multiphoton microscopy geeks: aberrations caused by vertical micro-interfaces appear to be a significant contrast mechanism in polarized THG imaging. 😎
Reposted by Chiara Stringari
Finally, we illustrate the relevance of pTHG microscopy for characterizing myelin distribution at different scales in fixed mouse and human brain tissue.
July 16, 2025 at 1:39 PM
Finally, we illustrate the relevance of pTHG microscopy for characterizing myelin distribution at different scales in fixed mouse and human brain tissue.
Reposted by Chiara Stringari
Our study presents a systematic characterization of polarized THG (pTHG) signals from individual axons, enabling the derivation of myelin scores in various systems. 🐭🐟
We confirm the sensitivity of THG for myelin in mouse tissue and detect early axon development in zebrafish.
We confirm the sensitivity of THG for myelin in mouse tissue and detect early axon development in zebrafish.
July 16, 2025 at 1:39 PM
Our study presents a systematic characterization of polarized THG (pTHG) signals from individual axons, enabling the derivation of myelin scores in various systems. 🐭🐟
We confirm the sensitivity of THG for myelin in mouse tissue and detect early axon development in zebrafish.
We confirm the sensitivity of THG for myelin in mouse tissue and detect early axon development in zebrafish.
Reposted by Chiara Stringari
We show that axons exhibit complex pTHG profiles that depend on axon morphology and can't be explained by classical models. We establish a numerical strategy to relate pTHG profiles to axon diameter and myelin thickness, taking into account myelin-induced optical aberrations.
July 16, 2025 at 1:39 PM
We show that axons exhibit complex pTHG profiles that depend on axon morphology and can't be explained by classical models. We establish a numerical strategy to relate pTHG profiles to axon diameter and myelin thickness, taking into account myelin-induced optical aberrations.
Reposted by Chiara Stringari
Multiscale characterization of myelin distribution with polarized THG microscopy
Morizet et al, Optica 2025 doi.org/10.1364/OPTI...
@laboptbio.bsky.social @institutducerveau.bsky.social @cnrs.fr @ip-paris.bsky.social @inserm.fr
(1/8)
Morizet et al, Optica 2025 doi.org/10.1364/OPTI...
@laboptbio.bsky.social @institutducerveau.bsky.social @cnrs.fr @ip-paris.bsky.social @inserm.fr
(1/8)
July 16, 2025 at 1:39 PM
Multiscale characterization of myelin distribution with polarized THG microscopy
Morizet et al, Optica 2025 doi.org/10.1364/OPTI...
@laboptbio.bsky.social @institutducerveau.bsky.social @cnrs.fr @ip-paris.bsky.social @inserm.fr
(1/8)
Morizet et al, Optica 2025 doi.org/10.1364/OPTI...
@laboptbio.bsky.social @institutducerveau.bsky.social @cnrs.fr @ip-paris.bsky.social @inserm.fr
(1/8)
Reposted by Chiara Stringari
By #J_Morizet #N_Olivier #MS_Aigrot #P_Mahou #E_Martin #A_Desmazieres #B_Stankoff @chiarastringari.bsky.social
🔬🌟 Find out how Third Harmonic Generation (THG) microscopy could help advance myelin biomedical research! 🧠
🔬🌟 Find out how Third Harmonic Generation (THG) microscopy could help advance myelin biomedical research! 🧠
July 16, 2025 at 1:39 PM
By #J_Morizet #N_Olivier #MS_Aigrot #P_Mahou #E_Martin #A_Desmazieres #B_Stankoff @chiarastringari.bsky.social
🔬🌟 Find out how Third Harmonic Generation (THG) microscopy could help advance myelin biomedical research! 🧠
🔬🌟 Find out how Third Harmonic Generation (THG) microscopy could help advance myelin biomedical research! 🧠
Reposted by Chiara Stringari
Congratulations to Amelie Elouin on her brilliant defence of her PhD thesis, entitled 'Investigating the role of Myosin II in collective cell migration during gastrulation in the zebrafish Danio rerio' !
July 11, 2025 at 9:12 AM
Congratulations to Amelie Elouin on her brilliant defence of her PhD thesis, entitled 'Investigating the role of Myosin II in collective cell migration during gastrulation in the zebrafish Danio rerio' !
Congratulations @caporalclement.bsky.social
And it was an honor to have you at LOB!
And it was an honor to have you at LOB!
Congratulations to @caporalclement.bsky.social on his brilliant defence of his PhD thesis, entitled 'Quantitative Analysis of Large Volume Imaging in Developmental Neurobiology' !
July 1, 2025 at 2:07 PM
Congratulations @caporalclement.bsky.social
And it was an honor to have you at LOB!
And it was an honor to have you at LOB!
Reposted by Chiara Stringari
Excited to be in Genoa for the #WeberSymposium2025
A few days of all fun things fluorescence ahead 🔬🎆🌈
Starting out with an account of the seminal contributions by Gregorio Weber presented by the amazing Dave Jameson
A few days of all fun things fluorescence ahead 🔬🎆🌈
Starting out with an account of the seminal contributions by Gregorio Weber presented by the amazing Dave Jameson
June 15, 2025 at 5:15 PM
Excited to be in Genoa for the #WeberSymposium2025
A few days of all fun things fluorescence ahead 🔬🎆🌈
Starting out with an account of the seminal contributions by Gregorio Weber presented by the amazing Dave Jameson
A few days of all fun things fluorescence ahead 🔬🎆🌈
Starting out with an account of the seminal contributions by Gregorio Weber presented by the amazing Dave Jameson
The talk "Fluorescence Lifetime Microscopy (FLIM) for label-free metabolic imaging of living tissues" given at the #VirtualPub of @eurobioimaging.bsky.social is now online!
#FLIM
www.youtube.com/watch?v=WC1V...
#FLIM
www.youtube.com/watch?v=WC1V...
June 15, 2025 at 1:47 PM
The talk "Fluorescence Lifetime Microscopy (FLIM) for label-free metabolic imaging of living tissues" given at the #VirtualPub of @eurobioimaging.bsky.social is now online!
#FLIM
www.youtube.com/watch?v=WC1V...
#FLIM
www.youtube.com/watch?v=WC1V...
Reposted by Chiara Stringari
Scientist colleagues, write to your hometown paper and tell folks about your work, what motivates it, and what impact it could have. Aim for publication June 16.
Federal research cuts impact local economies, and stall progress.
Publish an opinion piece in your hometown paper on June 16th to SPREAD THE WORD about how scientific research contributes to the everyday health and wealth of the general public.
#McClintockLetters
blogs.cornell.edu/asap/events-...
Publish an opinion piece in your hometown paper on June 16th to SPREAD THE WORD about how scientific research contributes to the everyday health and wealth of the general public.
#McClintockLetters
blogs.cornell.edu/asap/events-...
April 23, 2025 at 5:35 PM
Scientist colleagues, write to your hometown paper and tell folks about your work, what motivates it, and what impact it could have. Aim for publication June 16.
Reposted by Chiara Stringari
Congratulations to Stella Dees for defending her thesis on "Multicontrast 3P-microscopy for biological tissue imaging"
April 9, 2025 at 9:28 AM
Congratulations to Stella Dees for defending her thesis on "Multicontrast 3P-microscopy for biological tissue imaging"
Reposted by Chiara Stringari
Congratulation to Giulia Galante for her thesis defense about the "Characterization and physico-chemical monitoring of collagen degradation in parchments by polarization-resolved multiphoton microscopy!
April 7, 2025 at 3:55 PM
Congratulation to Giulia Galante for her thesis defense about the "Characterization and physico-chemical monitoring of collagen degradation in parchments by polarization-resolved multiphoton microscopy!
Reposted by Chiara Stringari
📰 New article published in @nature.com entitled "A human brain map of mitochondrial respiratory capacity and diversity" 🧠
An international research team has created a map revealing the diversity of #mitochondrial phenotypes in the human #brain
✒️ By @micheltds.bsky.social and all
📌 For more ⬇️
An international research team has created a map revealing the diversity of #mitochondrial phenotypes in the human #brain
✒️ By @micheltds.bsky.social and all
📌 For more ⬇️
A human brain map of mitochondrial respiratory capacity and diversity - Nature
The ability to physically partition the human brain at a spatial resolution comparable to neuroimaging methods enabled the development of a brain-wide atlas of mitochondrial content, specialization an...
www.nature.com
March 26, 2025 at 4:14 PM
📰 New article published in @nature.com entitled "A human brain map of mitochondrial respiratory capacity and diversity" 🧠
An international research team has created a map revealing the diversity of #mitochondrial phenotypes in the human #brain
✒️ By @micheltds.bsky.social and all
📌 For more ⬇️
An international research team has created a map revealing the diversity of #mitochondrial phenotypes in the human #brain
✒️ By @micheltds.bsky.social and all
📌 For more ⬇️
Reposted by Chiara Stringari
NEW: The University of California has announced a hiring freeze and additional cuts -- in travel, maintenance and other areas -- in response to uncertainty over the the future of federal funding during the Trump administration: www.latimes.com/california/s...
University of California orders hiring freeze, cuts in response to Trump threats
As the Trump administration threatens to pull federal funds from universities, including those for medical and scientific research, the University of California has announced a hiring freeze and addit...
www.latimes.com
March 19, 2025 at 5:22 PM
NEW: The University of California has announced a hiring freeze and additional cuts -- in travel, maintenance and other areas -- in response to uncertainty over the the future of federal funding during the Trump administration: www.latimes.com/california/s...
University of California orders hiring freeze, cuts in response to Trump threats
www.latimes.com/california/s...
www.latimes.com/california/s...
University of California orders hiring freeze, cuts in response to Trump threats
As the Trump administration threatens to pull federal funds from universities, including for medical and scientific research, the University of California has announced a hiring freeze and additional ...
www.latimes.com
March 19, 2025 at 11:55 PM
University of California orders hiring freeze, cuts in response to Trump threats
www.latimes.com/california/s...
www.latimes.com/california/s...