Chiara Stringari
@chiarastringari.bsky.social
Scientist at @cnrs.bsky.social @laboptbio.bsky.social
https://lob.ip-paris.fr/en/chiara-stringari
Label-free optical microscopy and metabolic imaging.
'Science doesn't care about what you believe'
https://lob.ip-paris.fr/en/chiara-stringari
Label-free optical microscopy and metabolic imaging.
'Science doesn't care about what you believe'
Reposted by Chiara Stringari
📢 LOB Seminars are back!
🗓 29 Jan 2026 | 11:00am
📍 Amphi Poisson
🎤 Baptiste Blochet (Saint-Pérès Paris Institute for the Neurosciences – SPPIN)
“Multiplexed Phase Imaging: From Laser Metrology to Super-Resolution Microscopy”
Looking forward to seeing you there!
lob.ip-paris.fr/en/events/se...
🗓 29 Jan 2026 | 11:00am
📍 Amphi Poisson
🎤 Baptiste Blochet (Saint-Pérès Paris Institute for the Neurosciences – SPPIN)
“Multiplexed Phase Imaging: From Laser Metrology to Super-Resolution Microscopy”
Looking forward to seeing you there!
lob.ip-paris.fr/en/events/se...
Seminar of Baptiste Blochet - Saint-Peres Paris Institute for the Neurosciences (SPPIN)
11:00am, Ecole Polytechnique, Amphi POISSON
lob.ip-paris.fr
January 23, 2026 at 11:50 AM
📢 LOB Seminars are back!
🗓 29 Jan 2026 | 11:00am
📍 Amphi Poisson
🎤 Baptiste Blochet (Saint-Pérès Paris Institute for the Neurosciences – SPPIN)
“Multiplexed Phase Imaging: From Laser Metrology to Super-Resolution Microscopy”
Looking forward to seeing you there!
lob.ip-paris.fr/en/events/se...
🗓 29 Jan 2026 | 11:00am
📍 Amphi Poisson
🎤 Baptiste Blochet (Saint-Pérès Paris Institute for the Neurosciences – SPPIN)
“Multiplexed Phase Imaging: From Laser Metrology to Super-Resolution Microscopy”
Looking forward to seeing you there!
lob.ip-paris.fr/en/events/se...
Our paper “Label-free nonlinear microscopy probes cellular metabolism and myelin dynamics in live tissue” is published in @commsbio.nature.com, thanks to an exciting collaboration between @laboptbio.bsky.social and @institutducerveau.bsky.social
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Label-free nonlinear microscopy probes cellular metabolism and myelin dynamics in live tissue - Communications Biology
Multimodal label-free nonlinear microscopy and advanced image analysis map single-cell metabolism and myelin dynamics in live cerebellar tissue during demyelination, supporting research in neuroinflam...
www.nature.com
January 7, 2026 at 4:27 PM
Our paper “Label-free nonlinear microscopy probes cellular metabolism and myelin dynamics in live tissue” is published in @commsbio.nature.com, thanks to an exciting collaboration between @laboptbio.bsky.social and @institutducerveau.bsky.social
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Reposted by Chiara Stringari
💡 New guidelines aim to standardize label-free optical metabolic imaging, a technique that uses light to study cell metabolism without dyes.
Consistency could lead to more accurate, reproducible results in cancer & drug development research. Read the #SPIE_JBO article: https://bit.ly/4isPMFc
Consistency could lead to more accurate, reproducible results in cancer & drug development research. Read the #SPIE_JBO article: https://bit.ly/4isPMFc
December 10, 2025 at 5:14 PM
💡 New guidelines aim to standardize label-free optical metabolic imaging, a technique that uses light to study cell metabolism without dyes.
Consistency could lead to more accurate, reproducible results in cancer & drug development research. Read the #SPIE_JBO article: https://bit.ly/4isPMFc
Consistency could lead to more accurate, reproducible results in cancer & drug development research. Read the #SPIE_JBO article: https://bit.ly/4isPMFc
Reposted by Chiara Stringari
L'équipe de microscopie avancée du @laboptbio.bsky.social
adossée à la platforme Morphoscope du noeud Ile-de France-Sud de @france-bioimaging.bsky.social, est à la recherche d'un IR en bioimage informatique.
emploi.cnrs.fr/Offres/MOBIN...
adossée à la platforme Morphoscope du noeud Ile-de France-Sud de @france-bioimaging.bsky.social, est à la recherche d'un IR en bioimage informatique.
emploi.cnrs.fr/Offres/MOBIN...
Portail Emploi CNRS - Offre d'emploi - Ingénieur-e en bio-imagerie computationnelle H/F
Prendre en charge la gestion de données de bio-imagerie obtenues lors d'expériences de microscopie multimodale : stockage, gestion, analyse automatisée et visualisation ainsi que ingénierie logicielle des outils développés.
emploi.cnrs.fr
December 9, 2025 at 11:34 AM
L'équipe de microscopie avancée du @laboptbio.bsky.social
adossée à la platforme Morphoscope du noeud Ile-de France-Sud de @france-bioimaging.bsky.social, est à la recherche d'un IR en bioimage informatique.
emploi.cnrs.fr/Offres/MOBIN...
adossée à la platforme Morphoscope du noeud Ile-de France-Sud de @france-bioimaging.bsky.social, est à la recherche d'un IR en bioimage informatique.
emploi.cnrs.fr/Offres/MOBIN...
Reposted by Chiara Stringari
Congratulations to Poncia Nyembo Kasongo on the brilliant defense of his PhD thesis "Second Harmonic Generation Imaging of the Structure of Healthy and Pathological Corneas" !
November 28, 2025 at 6:18 PM
Congratulations to Poncia Nyembo Kasongo on the brilliant defense of his PhD thesis "Second Harmonic Generation Imaging of the Structure of Healthy and Pathological Corneas" !
Reposted by Chiara Stringari
This is the result of a meeting held this summer in Stockholm, organized by the Royal Swedish Academy of Sciences, where I was one of the attendees.
Proposed actions against fake science presented after meeting
www.kva.se/en/news/prop...
Proposed actions against fake science presented after meeting
www.kva.se/en/news/prop...
November 9, 2025 at 8:54 PM
This is the result of a meeting held this summer in Stockholm, organized by the Royal Swedish Academy of Sciences, where I was one of the attendees.
Proposed actions against fake science presented after meeting
www.kva.se/en/news/prop...
Proposed actions against fake science presented after meeting
www.kva.se/en/news/prop...
Reposted by Chiara Stringari
More press @FinancialTimes [Gift link]:
A tide of fabricated research risks scientific integrity
Manipulation, disinformation and fakery could lead to a knowledge collapse
www.ft.com/content/a1c6...
A tide of fabricated research risks scientific integrity
Manipulation, disinformation and fakery could lead to a knowledge collapse
www.ft.com/content/a1c6...
A tide of fabricated research risks scientific integrity
[FREE TO READ] Manipulation, disinformation and fakery could lead to a knowledge collapse
www.ft.com
November 9, 2025 at 8:45 PM
More press @FinancialTimes [Gift link]:
A tide of fabricated research risks scientific integrity
Manipulation, disinformation and fakery could lead to a knowledge collapse
www.ft.com/content/a1c6...
A tide of fabricated research risks scientific integrity
Manipulation, disinformation and fakery could lead to a knowledge collapse
www.ft.com/content/a1c6...
Reposted by Chiara Stringari
Reformation of science publishing: the Stockholm Declaration
A call to action for universities, academies, science organizations and funders to unite and join this effort.
Bernhard Sabel and Dan Larhammar
royalsocietypublishing.org/doi/10.1098/...
A call to action for universities, academies, science organizations and funders to unite and join this effort.
Bernhard Sabel and Dan Larhammar
royalsocietypublishing.org/doi/10.1098/...
Reformation of science publishing: the Stockholm Declaration | Royal Society Open Science
Science relies on integrity and trustworthiness. But scientists under career pressure
are lured to purchase fake publications from ‘paper mills’ that use AI-generated data,
text and image fabrication....
royalsocietypublishing.org
November 9, 2025 at 8:43 PM
Reformation of science publishing: the Stockholm Declaration
A call to action for universities, academies, science organizations and funders to unite and join this effort.
Bernhard Sabel and Dan Larhammar
royalsocietypublishing.org/doi/10.1098/...
A call to action for universities, academies, science organizations and funders to unite and join this effort.
Bernhard Sabel and Dan Larhammar
royalsocietypublishing.org/doi/10.1098/...
Excited to share that our international consensus guidelines for cellular, label-free optical metabolic imaging have been published in the Journal of Biomedical Optics.
www.spiedigitallibrary.org/journals/jou...
#metabolicimaging #labelfree
www.spiedigitallibrary.org/journals/jou...
#metabolicimaging #labelfree
www.spiedigitallibrary.org
November 17, 2025 at 10:53 AM
Excited to share that our international consensus guidelines for cellular, label-free optical metabolic imaging have been published in the Journal of Biomedical Optics.
www.spiedigitallibrary.org/journals/jou...
#metabolicimaging #labelfree
www.spiedigitallibrary.org/journals/jou...
#metabolicimaging #labelfree
A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular l-lactate dynamics
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular l-lactate dynamics - Nature Communications
l-lactate is a key metabolite supporting neuronal activity, but methods to monitor l-lactate dynamics alongside neuronal activity in vivo have been limited. Here, authors report R-eLACCO2.1, a red flu...
www.nature.com
October 31, 2025 at 8:18 AM
A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular l-lactate dynamics
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Chiara Stringari
Wrapping up #Mifobio2025!
What I love most about this conference is how it reminds me that science is, above all, a collaborative effort. Nothing beats the sense of community here. See you in 2 years!
Check the Imabio @gdrimabio.bsky.social website for course and seminar replays soon imabio-cnrs.fr
What I love most about this conference is how it reminds me that science is, above all, a collaborative effort. Nothing beats the sense of community here. See you in 2 years!
Check the Imabio @gdrimabio.bsky.social website for course and seminar replays soon imabio-cnrs.fr
October 22, 2025 at 6:55 PM
Wrapping up #Mifobio2025!
What I love most about this conference is how it reminds me that science is, above all, a collaborative effort. Nothing beats the sense of community here. See you in 2 years!
Check the Imabio @gdrimabio.bsky.social website for course and seminar replays soon imabio-cnrs.fr
What I love most about this conference is how it reminds me that science is, above all, a collaborative effort. Nothing beats the sense of community here. See you in 2 years!
Check the Imabio @gdrimabio.bsky.social website for course and seminar replays soon imabio-cnrs.fr
Here you can find the slides of the MIFOBIO 2025 Workshop "A-07 Analyzing FLIM data for metabolic imaging applications with Phasor Analysis" using FLUTE software, with Xiaotong Yuan.
zenodo.org/records/1736...
#mifobio2025
zenodo.org/records/1736...
#mifobio2025
October 16, 2025 at 8:18 AM
Here you can find the slides of the MIFOBIO 2025 Workshop "A-07 Analyzing FLIM data for metabolic imaging applications with Phasor Analysis" using FLUTE software, with Xiaotong Yuan.
zenodo.org/records/1736...
#mifobio2025
zenodo.org/records/1736...
#mifobio2025
Amazing talk on “Mechanobiology of the Mitotic Spindle” by @ivatolic.bsky.social at #mifobio2025 @gdrimabio.bsky.social
October 15, 2025 at 8:44 PM
Amazing talk on “Mechanobiology of the Mitotic Spindle” by @ivatolic.bsky.social at #mifobio2025 @gdrimabio.bsky.social
Reposted by Chiara Stringari
(2025/10/08) Congratulations to @chiarastringari.bsky.social on the defense of her Habilitation à Diriger les Recherches (HDR) "Label-free multimodal non-linear optical microscopy for functional imaging of living tissues" !
October 9, 2025 at 9:50 AM
(2025/10/08) Congratulations to @chiarastringari.bsky.social on the defense of her Habilitation à Diriger les Recherches (HDR) "Label-free multimodal non-linear optical microscopy for functional imaging of living tissues" !
Over a decade at @laboptbio.bsky.social at @polytechniqueparis.bsky.social !
September 3, 2025 at 11:58 AM
Over a decade at @laboptbio.bsky.social at @polytechniqueparis.bsky.social !
Reposted by Chiara Stringari
Happy to finally publish this work… Congrats authors and thanks funders @agencerecherche.bsky.social #FondationBettencourtSchueller
July 16, 2025 at 1:39 PM
Happy to finally publish this work… Congrats authors and thanks funders @agencerecherche.bsky.social #FondationBettencourtSchueller
Reposted by Chiara Stringari
These findings help to establish THG microscopy as a quantitative, multiscale imaging technique, paving the way for new applications. 📖 #Neuroscience #Myelin #THG #Microscopy #Research
July 16, 2025 at 1:39 PM
These findings help to establish THG microscopy as a quantitative, multiscale imaging technique, paving the way for new applications. 📖 #Neuroscience #Myelin #THG #Microscopy #Research
Reposted by Chiara Stringari
Fun fact for multiphoton microscopy geeks: aberrations caused by vertical micro-interfaces appear to be a significant contrast mechanism in polarized THG imaging. 😎
July 16, 2025 at 1:39 PM
Fun fact for multiphoton microscopy geeks: aberrations caused by vertical micro-interfaces appear to be a significant contrast mechanism in polarized THG imaging. 😎
Reposted by Chiara Stringari
Finally, we illustrate the relevance of pTHG microscopy for characterizing myelin distribution at different scales in fixed mouse and human brain tissue.
July 16, 2025 at 1:39 PM
Finally, we illustrate the relevance of pTHG microscopy for characterizing myelin distribution at different scales in fixed mouse and human brain tissue.
Reposted by Chiara Stringari
Our study presents a systematic characterization of polarized THG (pTHG) signals from individual axons, enabling the derivation of myelin scores in various systems. 🐭🐟
We confirm the sensitivity of THG for myelin in mouse tissue and detect early axon development in zebrafish.
We confirm the sensitivity of THG for myelin in mouse tissue and detect early axon development in zebrafish.
July 16, 2025 at 1:39 PM
Our study presents a systematic characterization of polarized THG (pTHG) signals from individual axons, enabling the derivation of myelin scores in various systems. 🐭🐟
We confirm the sensitivity of THG for myelin in mouse tissue and detect early axon development in zebrafish.
We confirm the sensitivity of THG for myelin in mouse tissue and detect early axon development in zebrafish.
Reposted by Chiara Stringari
We show that axons exhibit complex pTHG profiles that depend on axon morphology and can't be explained by classical models. We establish a numerical strategy to relate pTHG profiles to axon diameter and myelin thickness, taking into account myelin-induced optical aberrations.
July 16, 2025 at 1:39 PM
We show that axons exhibit complex pTHG profiles that depend on axon morphology and can't be explained by classical models. We establish a numerical strategy to relate pTHG profiles to axon diameter and myelin thickness, taking into account myelin-induced optical aberrations.
Reposted by Chiara Stringari
Multiscale characterization of myelin distribution with polarized THG microscopy
Morizet et al, Optica 2025 doi.org/10.1364/OPTI...
@laboptbio.bsky.social @institutducerveau.bsky.social @cnrs.fr @ip-paris.bsky.social @inserm.fr
(1/8)
Morizet et al, Optica 2025 doi.org/10.1364/OPTI...
@laboptbio.bsky.social @institutducerveau.bsky.social @cnrs.fr @ip-paris.bsky.social @inserm.fr
(1/8)
July 16, 2025 at 1:39 PM
Multiscale characterization of myelin distribution with polarized THG microscopy
Morizet et al, Optica 2025 doi.org/10.1364/OPTI...
@laboptbio.bsky.social @institutducerveau.bsky.social @cnrs.fr @ip-paris.bsky.social @inserm.fr
(1/8)
Morizet et al, Optica 2025 doi.org/10.1364/OPTI...
@laboptbio.bsky.social @institutducerveau.bsky.social @cnrs.fr @ip-paris.bsky.social @inserm.fr
(1/8)
Reposted by Chiara Stringari
By #J_Morizet #N_Olivier #MS_Aigrot #P_Mahou #E_Martin #A_Desmazieres #B_Stankoff @chiarastringari.bsky.social
🔬🌟 Find out how Third Harmonic Generation (THG) microscopy could help advance myelin biomedical research! 🧠
🔬🌟 Find out how Third Harmonic Generation (THG) microscopy could help advance myelin biomedical research! 🧠
July 16, 2025 at 1:39 PM
By #J_Morizet #N_Olivier #MS_Aigrot #P_Mahou #E_Martin #A_Desmazieres #B_Stankoff @chiarastringari.bsky.social
🔬🌟 Find out how Third Harmonic Generation (THG) microscopy could help advance myelin biomedical research! 🧠
🔬🌟 Find out how Third Harmonic Generation (THG) microscopy could help advance myelin biomedical research! 🧠
Reposted by Chiara Stringari
Congratulations to Amelie Elouin on her brilliant defence of her PhD thesis, entitled 'Investigating the role of Myosin II in collective cell migration during gastrulation in the zebrafish Danio rerio' !
July 11, 2025 at 9:12 AM
Congratulations to Amelie Elouin on her brilliant defence of her PhD thesis, entitled 'Investigating the role of Myosin II in collective cell migration during gastrulation in the zebrafish Danio rerio' !