Chemical Biology Services
@chembl.bsky.social
The Chemical Biology Services team at EMBL-EBI provides free resources supporting drug discovery and handling small molecules in biological databases.
Pinned
Registration is now open at www.ebi.ac.uk/about/events...
We've been curating the Target Protein Degradation (TPD) data in ChEMBL. Read more at chembl.blogspot.com/2026/01/expl...
Exploring Targeted Protein Degradation Data in ChEMBL
Drug modalities continue to evolve and the capture of data from recent literature ensures that ChEMBL remains up-to-date with recent dev...
chembl.blogspot.com
January 14, 2026 at 5:51 PM
We've been curating the Target Protein Degradation (TPD) data in ChEMBL. Read more at chembl.blogspot.com/2026/01/expl...
Registration is now open at www.ebi.ac.uk/about/events...
January 14, 2026 at 5:50 PM
Registration is now open at www.ebi.ac.uk/about/events...
A blogpost on changes to ChEMBL data deposition:
chembl.blogspot.com/2026/01/chan...
...and not unrelated, a recent talk I gave on why data curation is needed and what it involves:
github.com/chembl/prese...
chembl.blogspot.com/2026/01/chan...
...and not unrelated, a recent talk I gave on why data curation is needed and what it involves:
github.com/chembl/prese...
Changes to ChEMBL Data Deposition
Over the years, ChEMBL has accepted 336 datasets deposited by the community. In fact, these data now comprise around 50% of the bioactivity ...
chembl.blogspot.com
January 8, 2026 at 3:58 PM
A blogpost on changes to ChEMBL data deposition:
chembl.blogspot.com/2026/01/chan...
...and not unrelated, a recent talk I gave on why data curation is needed and what it involves:
github.com/chembl/prese...
chembl.blogspot.com/2026/01/chan...
...and not unrelated, a recent talk I gave on why data curation is needed and what it involves:
github.com/chembl/prese...
Last chance (closing dates Jan 11) to apply for open positions in the team:
www.ebi.ac.uk/about/teams/...
1. Technical Lead for the team - could be someone with either a scientific or computing background.
2. NLP Data Scientist/Scientific Data Engineer, to develop a drug side effect resource
www.ebi.ac.uk/about/teams/...
1. Technical Lead for the team - could be someone with either a scientific or computing background.
2. NLP Data Scientist/Scientific Data Engineer, to develop a drug side effect resource
Joining the group – Chemical Biology Services
www.ebi.ac.uk
January 5, 2026 at 11:55 AM
Last chance (closing dates Jan 11) to apply for open positions in the team:
www.ebi.ac.uk/about/teams/...
1. Technical Lead for the team - could be someone with either a scientific or computing background.
2. NLP Data Scientist/Scientific Data Engineer, to develop a drug side effect resource
www.ebi.ac.uk/about/teams/...
1. Technical Lead for the team - could be someone with either a scientific or computing background.
2. NLP Data Scientist/Scientific Data Engineer, to develop a drug side effect resource
The date for the ChEMBL UGM has been fixed for June 10-11 2026. The website is up at www.ebi.ac.uk/about/events... and registration opens in January.
See you next year!
See you next year!
2nd ChEMBL User Group Meeting – EMBL-EBI Events
www.ebi.ac.uk
December 17, 2025 at 12:42 PM
The date for the ChEMBL UGM has been fixed for June 10-11 2026. The website is up at www.ebi.ac.uk/about/events... and registration opens in January.
See you next year!
See you next year!
Reposted by Chemical Biology Services
NEW: NLP data scientists/scientific data engineers at @ebi.embl.org
Develop a comprehensive open source side effect resource and standardised AI/ML training sets to improve early identification of safety liabilities
Apply by 11 January
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Develop a comprehensive open source side effect resource and standardised AI/ML training sets to improve early identification of safety liabilities
Apply by 11 January
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
NLP Data Scientist/Scientific Data Engineer
About the team/job Safety and toxicology concerns remain one of the most persistent challenges in drug discovery. This is an exciting opportunity to join a multi-disciplinary team on a project to deve...
embl.wd103.myworkdayjobs.com
December 11, 2025 at 1:44 PM
NEW: NLP data scientists/scientific data engineers at @ebi.embl.org
Develop a comprehensive open source side effect resource and standardised AI/ML training sets to improve early identification of safety liabilities
Apply by 11 January
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Develop a comprehensive open source side effect resource and standardised AI/ML training sets to improve early identification of safety liabilities
Apply by 11 January
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Reposted by Chemical Biology Services
Text-mining tools have progressed a lot in the last two decades, and I'm excited to see what can be done now.
More info chembl.blogspot.com/2025/12/new-...
Apply here: embl.wd103.myworkdayjobs.com/EMBL/job/Hin... The position is at @ebi.embl.org
#ScienceJobs #AcademicSky #ChemSky #BioSky [3/3]
More info chembl.blogspot.com/2025/12/new-...
Apply here: embl.wd103.myworkdayjobs.com/EMBL/job/Hin... The position is at @ebi.embl.org
#ScienceJobs #AcademicSky #ChemSky #BioSky [3/3]
New position: NLP Data Scientist/Scientific Data Engineer
As part of a funded collaboration with Open Targets, there are two open positions as part of a team to develop a drug side effect resource:...
chembl.blogspot.com
December 11, 2025 at 6:49 PM
Text-mining tools have progressed a lot in the last two decades, and I'm excited to see what can be done now.
More info chembl.blogspot.com/2025/12/new-...
Apply here: embl.wd103.myworkdayjobs.com/EMBL/job/Hin... The position is at @ebi.embl.org
#ScienceJobs #AcademicSky #ChemSky #BioSky [3/3]
More info chembl.blogspot.com/2025/12/new-...
Apply here: embl.wd103.myworkdayjobs.com/EMBL/job/Hin... The position is at @ebi.embl.org
#ScienceJobs #AcademicSky #ChemSky #BioSky [3/3]
Reposted by Chemical Biology Services
...but life intervened and funding changed, so SIDER sideeffects.embl.de is unfortunately gathering dust since its last update in 2015.
But there's good news: @chembl.bsky.social and @opentargets.org are starting a new effort to mine the available data and produce a high-quality databases! [2/3]
But there's good news: @chembl.bsky.social and @opentargets.org are starting a new effort to mine the available data and produce a high-quality databases! [2/3]
December 11, 2025 at 6:49 PM
...but life intervened and funding changed, so SIDER sideeffects.embl.de is unfortunately gathering dust since its last update in 2015.
But there's good news: @chembl.bsky.social and @opentargets.org are starting a new effort to mine the available data and produce a high-quality databases! [2/3]
But there's good news: @chembl.bsky.social and @opentargets.org are starting a new effort to mine the available data and produce a high-quality databases! [2/3]
We are looking for a new Technical Lead for our group. This is an exciting opportunity for someone either from a scientific or informatics background to play a key role in our team which has a huge impact on the scientific communities that we serve: chembl.blogspot.com/2025/12/open...
Open Position: Technical Lead Chemical Biology Services
We are looking for a new Technical Lead to lead the technical maintenance and development of our group's services . This is an exciting opp...
chembl.blogspot.com
December 3, 2025 at 10:55 PM
We are looking for a new Technical Lead for our group. This is an exciting opportunity for someone either from a scientific or informatics background to play a key role in our team which has a huge impact on the scientific communities that we serve: chembl.blogspot.com/2025/12/open...
The ChEBI 2.0 paper has just been published by Nucleic Acids Research.
#chebi #ontology
academic.oup.com/nar/advance-...
#chebi #ontology
academic.oup.com/nar/advance-...
ChEBI: re-engineered for a sustainable future
Abstract. Chemical Entities of Biological Interest (ChEBI) is a high-quality, manually curated, and open-access database and ontology of chemical entities
academic.oup.com
November 28, 2025 at 12:53 PM
The ChEBI 2.0 paper has just been published by Nucleic Acids Research.
#chebi #ontology
academic.oup.com/nar/advance-...
#chebi #ontology
academic.oup.com/nar/advance-...
We've just released a webinar that provides background on the #chembl database alongside worked examples highlighting some common scenarios in drug discovery initiatives.
chembl.blogspot.com/2025/09/make...
chembl.blogspot.com/2025/09/make...
Make the most of the ChEMBL interface with our newest webinar!
Before starting a new drug discovery project, it’s useful to compile existing data on compounds and targets of interest. Open access bioacti...
chembl.blogspot.com
September 18, 2025 at 2:03 PM
We've just released a webinar that provides background on the #chembl database alongside worked examples highlighting some common scenarios in drug discovery initiatives.
chembl.blogspot.com/2025/09/make...
chembl.blogspot.com/2025/09/make...
We have gone back in time and generated SQLite files for all releases of #ChEMBL from version 1 onwards making it easier to carry out analyses across ChEMBL versions.
chembl.blogspot.com/2025/09/sqli...
chembl.blogspot.com/2025/09/sqli...
chembl.blogspot.com
September 15, 2025 at 5:10 PM
We have gone back in time and generated SQLite files for all releases of #ChEMBL from version 1 onwards making it easier to carry out analyses across ChEMBL versions.
chembl.blogspot.com/2025/09/sqli...
chembl.blogspot.com/2025/09/sqli...
Last chance to apply for this pivotal role, taking our services to the next level. Get in touch by end of Aug if interested...
We are inviting applications for a 3-year ARISE2 Postdoctoral Fellowship with the team. Read more on our blog at: chembl.blogspot.com/2025/07/invi...
Invite to apply for ARISE2 Postdoctoral Fellowship
The Chemical Biology Services team invites applications for a 3-year ARISE2 Postdoctoral Fellowship – a unique postdoctoral opportunity th...
chembl.blogspot.com
August 21, 2025 at 10:09 AM
Last chance to apply for this pivotal role, taking our services to the next level. Get in touch by end of Aug if interested...
Who would like to see 3D structures on ChEMBL? (*my hand shoots up*)
Latest @chemrxiv.org preprint! "Scalable Low-Energy Molecular Conformer Generation with QM Accuracy" Collab. w/ NVIDIA
We created ChEMBL3D, dataset of 3D structures for 1.8M drug-like molecules from ChEMBL. All optimized with solvent effect. #chemsky #compchem chemrxiv.org/engage/chemr...
We created ChEMBL3D, dataset of 3D structures for 1.8M drug-like molecules from ChEMBL. All optimized with solvent effect. #chemsky #compchem chemrxiv.org/engage/chemr...
Cambridge Press Open Research Platform server
Cambridge Press Open Research Platform server
chemrxiv.org
August 20, 2025 at 4:35 PM
Who would like to see 3D structures on ChEMBL? (*my hand shoots up*)
In support of @egonw.mastodon.social.ap.brid.gy 's 'One Million IUPAC Names' project, we have just released more than 4 million IUPAC names text-mined from patents.
Read more at: chembl.blogspot.com/2025/08/unle...
Read more at: chembl.blogspot.com/2025/08/unle...
Unleashing 4 million IUPAC names into the wild
In support of Egon Willighagen's ' One Million IUPAC Names ' project, we have just released more than 4 million IUPAC names text-mined from...
chembl.blogspot.com
August 8, 2025 at 11:23 AM
In support of @egonw.mastodon.social.ap.brid.gy 's 'One Million IUPAC Names' project, we have just released more than 4 million IUPAC names text-mined from patents.
Read more at: chembl.blogspot.com/2025/08/unle...
Read more at: chembl.blogspot.com/2025/08/unle...
A second post about the redevelopment of ChEBI, this time focussing on changes to the data products.
chembl.blogspot.com/2025/07/cheb...
chembl.blogspot.com/2025/07/cheb...
ChEBI 2.0 Data Products
Image generated using DALLE-3 Introduction Dear ChEBI users, If you have visited the ChEBI website recently, you have been able to intuit t...
chembl.blogspot.com
July 21, 2025 at 8:33 AM
A second post about the redevelopment of ChEBI, this time focussing on changes to the data products.
chembl.blogspot.com/2025/07/cheb...
chembl.blogspot.com/2025/07/cheb...
We are inviting applications for a 3-year ARISE2 Postdoctoral Fellowship with the team. Read more on our blog at: chembl.blogspot.com/2025/07/invi...
Invite to apply for ARISE2 Postdoctoral Fellowship
The Chemical Biology Services team invites applications for a 3-year ARISE2 Postdoctoral Fellowship – a unique postdoctoral opportunity th...
chembl.blogspot.com
July 14, 2025 at 7:24 PM
We are inviting applications for a 3-year ARISE2 Postdoctoral Fellowship with the team. Read more on our blog at: chembl.blogspot.com/2025/07/invi...
Reposted by Chemical Biology Services
🚨Our user survey is closing on 24 July.
Only a few days left to share your views. Please take 10 minutes to help us demonstrate the value of the data resources we manage with our collaborators.
Complete survey 👇 www.surveymonkey.com/r/QGFMBH8?ch...
🖥️🧬 #FAIRdata
Only a few days left to share your views. Please take 10 minutes to help us demonstrate the value of the data resources we manage with our collaborators.
Complete survey 👇 www.surveymonkey.com/r/QGFMBH8?ch...
🖥️🧬 #FAIRdata
July 14, 2025 at 3:22 PM
🚨Our user survey is closing on 24 July.
Only a few days left to share your views. Please take 10 minutes to help us demonstrate the value of the data resources we manage with our collaborators.
Complete survey 👇 www.surveymonkey.com/r/QGFMBH8?ch...
🖥️🧬 #FAIRdata
Only a few days left to share your views. Please take 10 minutes to help us demonstrate the value of the data resources we manage with our collaborators.
Complete survey 👇 www.surveymonkey.com/r/QGFMBH8?ch...
🖥️🧬 #FAIRdata
We would very much appreciate people taking the time to fill our impact survey. This helps makes the case for support for our resources. Survey closes on July 16th.
July 11, 2025 at 12:29 PM
We would very much appreciate people taking the time to fill our impact survey. This helps makes the case for support for our resources. Survey closes on July 16th.
Reposted by Chemical Biology Services
Last but by no means least, we chose to take a reversed approach and check which of our colocalised IBD genes were ALREADY drug targets for non-IBD diseases. With a little help from
@chembl.bsky.social
and
@opentargets.org
, we noticed two particularly interesting cases: PSEN2 and NDUFAF1…
@chembl.bsky.social
and
@opentargets.org
, we noticed two particularly interesting cases: PSEN2 and NDUFAF1…
July 8, 2025 at 8:52 AM
Last but by no means least, we chose to take a reversed approach and check which of our colocalised IBD genes were ALREADY drug targets for non-IBD diseases. With a little help from
@chembl.bsky.social
and
@opentargets.org
, we noticed two particularly interesting cases: PSEN2 and NDUFAF1…
@chembl.bsky.social
and
@opentargets.org
, we noticed two particularly interesting cases: PSEN2 and NDUFAF1…
The ChEMBL-og: Support ChEMBL - EMBL-EBI user survey! chembl.blogspot.com/2025/06/supp...
Support ChEMBL - EMBL-EBI user survey!
If our data resources have ever been of use to you, here’s your chance to give back! EMBL-EBI’s impact survey aims to understand the usage,...
chembl.blogspot.com
June 25, 2025 at 10:31 AM
The ChEMBL-og: Support ChEMBL - EMBL-EBI user survey! chembl.blogspot.com/2025/06/supp...
Just one week left to apply for this position in our team, as frontend developer:
embl.wd103.myworkdayjobs.com/EMBL/job/Hin...
embl.wd103.myworkdayjobs.com/EMBL/job/Hin...
Frontend Developer
We are looking for a talented frontend developer to join the Chemical Biology team at the European Bioinformatics Institute (EMBL-EBI) located on the Wellcome Genome Campus near Cambridge in the UK. T...
embl.wd103.myworkdayjobs.com
May 26, 2025 at 7:12 PM
Just one week left to apply for this position in our team, as frontend developer:
embl.wd103.myworkdayjobs.com/EMBL/job/Hin...
embl.wd103.myworkdayjobs.com/EMBL/job/Hin...
Reposted by Chemical Biology Services
As chemical data grows, turning names into machine-readable structures is key for discovery, automation, and data integration.
OPSIN – now hosted at EMBL-EBI – helps solve this by converting IUPAC names into chemical structures and other machine-readable formats.
www.ebi.ac.uk/about/news/u...
OPSIN – now hosted at EMBL-EBI – helps solve this by converting IUPAC names into chemical structures and other machine-readable formats.
www.ebi.ac.uk/about/news/u...
OPSIN chemical name-to-structure tool moves to EMBL-EBI
The Open Parser for Systematic IUPAC Nomenclature (OPSIN) allows users to convert chemical names into structures and machine-readable formats.
www.ebi.ac.uk
May 21, 2025 at 2:40 PM
As chemical data grows, turning names into machine-readable structures is key for discovery, automation, and data integration.
OPSIN – now hosted at EMBL-EBI – helps solve this by converting IUPAC names into chemical structures and other machine-readable formats.
www.ebi.ac.uk/about/news/u...
OPSIN – now hosted at EMBL-EBI – helps solve this by converting IUPAC names into chemical structures and other machine-readable formats.
www.ebi.ac.uk/about/news/u...