Anthony Chang, MD
@changucanspare.bsky.social
Prof/renal pathologist at U of Chicago; ultimate complement and bile-iever; COI - Alexion, Apellis, Novartis, Otsuka, and I never met a kidney bx I didn't like
Reposted by Anthony Chang, MD
#Quiz:
A 16-year-old patient presented to an emergency department with a 3-week history of progressive headaches, nausea, vomiting, and bilateral blurry vision. Over the past 3 days, he developed chest pain and shortness of breath.
bit.ly/3WsjM9T
A 16-year-old patient presented to an emergency department with a 3-week history of progressive headaches, nausea, vomiting, and bilateral blurry vision. Over the past 3 days, he developed chest pain and shortness of breath.
bit.ly/3WsjM9T
November 15, 2025 at 11:00 AM
#Quiz:
A 16-year-old patient presented to an emergency department with a 3-week history of progressive headaches, nausea, vomiting, and bilateral blurry vision. Over the past 3 days, he developed chest pain and shortness of breath.
bit.ly/3WsjM9T
A 16-year-old patient presented to an emergency department with a 3-week history of progressive headaches, nausea, vomiting, and bilateral blurry vision. Over the past 3 days, he developed chest pain and shortness of breath.
bit.ly/3WsjM9T
Reposted by Anthony Chang, MD
🚦 The long-awaited #AJKD Core Curriculum update is here!
Join Drs. Susie Hu & Anthony Chang on Kidney Commute: Pitstop as they unpack what this means for nephrologists.
🎧 Don’t miss it: www.kidney.org/podcasts/kid...
Join Drs. Susie Hu & Anthony Chang on Kidney Commute: Pitstop as they unpack what this means for nephrologists.
🎧 Don’t miss it: www.kidney.org/podcasts/kid...
September 22, 2025 at 10:00 PM
🚦 The long-awaited #AJKD Core Curriculum update is here!
Join Drs. Susie Hu & Anthony Chang on Kidney Commute: Pitstop as they unpack what this means for nephrologists.
🎧 Don’t miss it: www.kidney.org/podcasts/kid...
Join Drs. Susie Hu & Anthony Chang on Kidney Commute: Pitstop as they unpack what this means for nephrologists.
🎧 Don’t miss it: www.kidney.org/podcasts/kid...
Kristen Tillquist, @nephrosage.bsky.social, me, and Susie Hu wrote this onconephrology topic for AJKD Core Curriculum
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
The Nephrologist’s Perspective in Evaluation and Management of Localized Renal Masses: Core Curriculum 2025
The evaluation and management of renal masses, predominantly of the clear cell renal cell carcinoma subtype, have been evolving over the past several …
www.sciencedirect.com
September 12, 2025 at 1:04 AM
Kristen Tillquist, @nephrosage.bsky.social, me, and Susie Hu wrote this onconephrology topic for AJKD Core Curriculum
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Anthony Chang, MD
We recently hosted our first roundtable event! In the first segment, the panel discusses the history of C3G and IC-MPGN, the heterogeneity of glomerulonephritis, and how new, specific disease definitions have come into focus. #nephsky #nephrology buff.ly/543raB8
C3G and IC-MPGN: The Past and Pathology (Roundtable) | Docwire News
A roundtable panel discusses the history of C3G and IC-MPGN, the heterogeneity of glomerulonephritis, and how new, specific disease definitions have come into focus.
buff.ly
August 20, 2025 at 8:15 PM
We recently hosted our first roundtable event! In the first segment, the panel discusses the history of C3G and IC-MPGN, the heterogeneity of glomerulonephritis, and how new, specific disease definitions have come into focus. #nephsky #nephrology buff.ly/543raB8
August 20, 2025 at 1:03 AM
Reposted by Anthony Chang, MD
We hosted our first live event on Friday, and look forward to sharing the videos soon! Thank you to @kidneyboy.bsky.social, @changucanspare.bsky.social, Roger Rodby, Cybele Ghossein, and Fernando Fervenza for participating. #nephrology #nephsky
August 4, 2025 at 9:50 PM
We hosted our first live event on Friday, and look forward to sharing the videos soon! Thank you to @kidneyboy.bsky.social, @changucanspare.bsky.social, Roger Rodby, Cybele Ghossein, and Fernando Fervenza for participating. #nephrology #nephsky
What an amazing year with our renal path fellow, Teo Feuerhake! He returns soon to Chile with his expertise as one of the few fellowship-trained renal pathologists. We'll miss him tremendously but glad for all the kidney dz pts who will benefit
June 16, 2025 at 1:29 PM
What an amazing year with our renal path fellow, Teo Feuerhake! He returns soon to Chile with his expertise as one of the few fellowship-trained renal pathologists. We'll miss him tremendously but glad for all the kidney dz pts who will benefit
Fantastic to have Hayde Ramos from Mexico spend 3 months with our renal path service. Formed a great team with our renal path fellow, Teo Feuerhake. Times flies when you get to work with these amazing people
June 10, 2025 at 12:36 AM
Fantastic to have Hayde Ramos from Mexico spend 3 months with our renal path service. Formed a great team with our renal path fellow, Teo Feuerhake. Times flies when you get to work with these amazing people
Reposted by Anthony Chang, MD
Our department is expanding and looking for an additional renal pathologist and another GI pathologist
Apply here: t.co/ZF8Y1uhQzi and t.co/SsDNqVlIBC
Apply here: t.co/ZF8Y1uhQzi and t.co/SsDNqVlIBC
http://apply.interfolio.com/158902
t.co
November 22, 2024 at 12:19 PM
Our department is expanding and looking for an additional renal pathologist and another GI pathologist
Apply here: t.co/ZF8Y1uhQzi and t.co/SsDNqVlIBC
Apply here: t.co/ZF8Y1uhQzi and t.co/SsDNqVlIBC
Reposted by Anthony Chang, MD
Congratulations to Dr Maria Picken for being the recipient of the John Gruhn Lifetime Achievement Award!
May 18, 2025 at 1:39 AM
Congratulations to Dr Maria Picken for being the recipient of the John Gruhn Lifetime Achievement Award!
20 years ago we would have diagnosed this as IgA nephropathy
May 13, 2025 at 11:33 AM
20 years ago we would have diagnosed this as IgA nephropathy
We need to train more nephropathologists to provide the correct diagnosis so that the nephrologists can properly manage these complex patients
We're pleased to present the expert speakers and panelists for the upcoming Workshop on Building Glomerular Disease Clinics, an initiative supporting nephrologists in establishing and sustaining GN Clinics.
📅 Date: June 14
⏰ Time: 9:00 AM – 1:00 PM PST
Register here: glomcon.org/for-mds/gn-c...
📅 Date: June 14
⏰ Time: 9:00 AM – 1:00 PM PST
Register here: glomcon.org/for-mds/gn-c...
May 12, 2025 at 8:12 PM
We need to train more nephropathologists to provide the correct diagnosis so that the nephrologists can properly manage these complex patients
Reposted by Anthony Chang, MD
6/10
Give me something clever to say
“I think of a smoldering AMR like a slowly growing leiomyoma/uterine fibroid. We don't use chemo and using it still might not stop its growth” by @changucanspare.bsky.social
Give me something clever to say
“I think of a smoldering AMR like a slowly growing leiomyoma/uterine fibroid. We don't use chemo and using it still might not stop its growth” by @changucanspare.bsky.social
May 10, 2025 at 10:42 PM
6/10
Give me something clever to say
“I think of a smoldering AMR like a slowly growing leiomyoma/uterine fibroid. We don't use chemo and using it still might not stop its growth” by @changucanspare.bsky.social
Give me something clever to say
“I think of a smoldering AMR like a slowly growing leiomyoma/uterine fibroid. We don't use chemo and using it still might not stop its growth” by @changucanspare.bsky.social
If it takes 25-30 years to lose your first half of nephrons, it won’t take another 25-30 years to lose the second half
A serum creatinine of 1.3 mg/dL is not alarming until you realize that it probably represents ~50% nephron loss, because that's what your creatinine would be if you donated a kidney
May 10, 2025 at 1:13 AM
If it takes 25-30 years to lose your first half of nephrons, it won’t take another 25-30 years to lose the second half
A serum creatinine of 1.3 mg/dL is not alarming until you realize that it probably represents ~50% nephron loss, because that's what your creatinine would be if you donated a kidney
May 9, 2025 at 10:20 AM
A serum creatinine of 1.3 mg/dL is not alarming until you realize that it probably represents ~50% nephron loss, because that's what your creatinine would be if you donated a kidney
Chronic kidney disease enhances alternative pathway activity: a new paradigm www.jci.org/articles/vie...
JCI -
Chronic kidney disease enhances alternative pathway activity: a new paradigm
www.jci.org
May 4, 2025 at 11:34 AM
Chronic kidney disease enhances alternative pathway activity: a new paradigm www.jci.org/articles/vie...
"If you are only going to do 1 biopsy, do the second" - Gary Hill
Rovin et al get the 2nd kidney bx in this lupus nephritis study using voclosporin and did not find CNI toxicity
acrjournals.onlinelibrary.wiley.com/doi/abs/10.1...
Rovin et al get the 2nd kidney bx in this lupus nephritis study using voclosporin and did not find CNI toxicity
acrjournals.onlinelibrary.wiley.com/doi/abs/10.1...
Effect of long‐term voclosporin treatment on renal histology in patients with active lupus nephritis with repeat renal biopsies
Objective This study characterized the impact of voclosporin on kidney histology in patients with lupus nephritis (LN) who had protocolized repeat kidney biopsies in the AURORA clinical trials. Me...
acrjournals.onlinelibrary.wiley.com
May 3, 2025 at 1:21 PM
"If you are only going to do 1 biopsy, do the second" - Gary Hill
Rovin et al get the 2nd kidney bx in this lupus nephritis study using voclosporin and did not find CNI toxicity
acrjournals.onlinelibrary.wiley.com/doi/abs/10.1...
Rovin et al get the 2nd kidney bx in this lupus nephritis study using voclosporin and did not find CNI toxicity
acrjournals.onlinelibrary.wiley.com/doi/abs/10.1...
Tony Chang
Renal pathologist at U of Chicago
1st #NephJC on BlueSky for me, will be lurking
Disclosure: I think active AMR mostly smolders and of course I worry that complement potentiates the pts who have worse outcomes as their DSAs fix complement
Renal pathologist at U of Chicago
1st #NephJC on BlueSky for me, will be lurking
Disclosure: I think active AMR mostly smolders and of course I worry that complement potentiates the pts who have worse outcomes as their DSAs fix complement
April 30, 2025 at 1:04 AM
Tony Chang
Renal pathologist at U of Chicago
1st #NephJC on BlueSky for me, will be lurking
Disclosure: I think active AMR mostly smolders and of course I worry that complement potentiates the pts who have worse outcomes as their DSAs fix complement
Renal pathologist at U of Chicago
1st #NephJC on BlueSky for me, will be lurking
Disclosure: I think active AMR mostly smolders and of course I worry that complement potentiates the pts who have worse outcomes as their DSAs fix complement
Bob Colvin, Lynn Cornell and I received our copies of the Chinese translation of our textbook
Bob said he didn’t find any typos but I haven’t given up yet
Bob said he didn’t find any typos but I haven’t given up yet
April 29, 2025 at 11:19 AM
Bob Colvin, Lynn Cornell and I received our copies of the Chinese translation of our textbook
Bob said he didn’t find any typos but I haven’t given up yet
Bob said he didn’t find any typos but I haven’t given up yet
Reposted by Anthony Chang, MD
SGLT2 inhibitors can have a complement inhibition effect.
By @changucanspare.bsky.social at @glomcon.org
By @changucanspare.bsky.social at @glomcon.org
April 27, 2025 at 3:35 PM
SGLT2 inhibitors can have a complement inhibition effect.
By @changucanspare.bsky.social at @glomcon.org
By @changucanspare.bsky.social at @glomcon.org
Reposted by Anthony Chang, MD
Scleroderma renal crisis only impacts ~10% of those with scleroderma and may be complement mediated.
By @changucanspare.bsky.social at @glomcon.org
By @changucanspare.bsky.social at @glomcon.org
April 27, 2025 at 3:33 PM
Scleroderma renal crisis only impacts ~10% of those with scleroderma and may be complement mediated.
By @changucanspare.bsky.social at @glomcon.org
By @changucanspare.bsky.social at @glomcon.org
Reposted by Anthony Chang, MD
In clinical laboratory studies for TMA, you may have relative (rather than absolute thrombocytopenia) and often do not see schistocytes on peripheral smears (or require serial measurements).
By @changucanspare.bsky.social at @glomcon.org
By @changucanspare.bsky.social at @glomcon.org
April 27, 2025 at 3:31 PM
In clinical laboratory studies for TMA, you may have relative (rather than absolute thrombocytopenia) and often do not see schistocytes on peripheral smears (or require serial measurements).
By @changucanspare.bsky.social at @glomcon.org
By @changucanspare.bsky.social at @glomcon.org
Reposted by Anthony Chang, MD
April 27, 2025 at 3:30 PM
OMG - we read the kidney bxs for Brown Medicine and have interacted on several occasions with Dr. Rasha Alawieh. She's an integral member of their busy transplant nephrology team. Need to bring her back ASAP as kidney transplant patients will be harmed by this
Are y'all seeing this? Papers mean NOTHING if you're not the right demographic. Transplant H1B doctor deported AGAINST court orders. Gift article. #BlackSky #MedSky
www.nytimes.com/2025/03/16/u...
www.nytimes.com/2025/03/16/u...
Brown University Professor and Doctor Is Deported to Lebanon Despite a Judge’s Order (Gift Article)
Dr. Rasha Alawieh, a kidney transplant specialist and Brown University professor who had a valid visa, was expelled in apparent defiance of a court order.
www.nytimes.com
March 17, 2025 at 11:04 AM
OMG - we read the kidney bxs for Brown Medicine and have interacted on several occasions with Dr. Rasha Alawieh. She's an integral member of their busy transplant nephrology team. Need to bring her back ASAP as kidney transplant patients will be harmed by this
Reposted by Anthony Chang, MD
🚨One Week Left: Apply for Kidney TREK 2025🚨
Hands-on nephrology experience + mentorship at your choice of location:
🏞️ MDIBL: Research with model organisms.
🏙️ UChicago: Renal physiology and procedures.
Apply by January 22 🔗https://www.asn-online.org/treks
📷 Credits: Arvin Halim
Hands-on nephrology experience + mentorship at your choice of location:
🏞️ MDIBL: Research with model organisms.
🏙️ UChicago: Renal physiology and procedures.
Apply by January 22 🔗https://www.asn-online.org/treks
📷 Credits: Arvin Halim
January 15, 2025 at 9:10 PM
🚨One Week Left: Apply for Kidney TREK 2025🚨
Hands-on nephrology experience + mentorship at your choice of location:
🏞️ MDIBL: Research with model organisms.
🏙️ UChicago: Renal physiology and procedures.
Apply by January 22 🔗https://www.asn-online.org/treks
📷 Credits: Arvin Halim
Hands-on nephrology experience + mentorship at your choice of location:
🏞️ MDIBL: Research with model organisms.
🏙️ UChicago: Renal physiology and procedures.
Apply by January 22 🔗https://www.asn-online.org/treks
📷 Credits: Arvin Halim