Claudia C. Weber
cc7740.bsky.social
Claudia C. Weber
@cc7740.bsky.social

Molecular evolution, genomes (lots of them, preferably weird), computational models. Stockholm, Sweden (she/her)
https://github.com/claudia-c-weber

Biology 38%
Political science 29%
Pinned
Our paper on myxozoan genomes is out now in G3! See thread below for a brief recap (slight change of title from the preprint, same content).

Thank you also to @arunsethuraman.bsky.social for handling the manuscript and @joannamasel.bsky.social for helpful comments.

academic.oup.com/g3journal/ad...

Reposted by Claudia Weber

Really, really happy that our work on microsporidian genomes is now out in @plosbiology.org! A huge thank you to my coauthors, my supervisors @mblaxter.bsky.social & @marakat.bsky.social, the editors @roliroberts.bsky.social & Joseph Heitman, and the reviewers ❤️ plos.io/48HsAQJ

My parents were contemplating a holiday in Sweden in October, and pointed out it was recently 30°C in Abisko

Ah, köttbilar, the famous Swedish meat cars.

LLMs would make great conspiracy theorists though. I was trying to identify the the hashing function used to map an identifier to a directory path, and the model claimed that my system is compromised because the output didn't match the prediction. Nope, my guess about the input was wrong...

Reposted by Claudia Weber

Have long-read data and want to know what you've really sequenced, and how much of it? Reliable taxonomic labels are often scarce if the target is from a less well-explored group. Fortunately, 2D embeddings from a VAE can tease apart different organisms in read sets:

www.biorxiv.org/content/10.1...
Disentangling Cobionts and Contamination in Long-Read Genomic Data using Sequence Composition
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org

Wouldn't want anyone's PMDD to go away, so they can "feel their emotions".

I'm more bemused by the lack of exterior blackout shutters. My grandma's house in Germany was nowhere near as warm as my apartment in Cambridge last week, even though it had hit 36°C there. It's as though I never left my top floor Philly row house apartment that didn't have window AC in the kitchen

Shiny wasp

Hymenopteran Hotel

Reposted by Claudia Weber

If EMBL-EBI managed data resources have ever saved you time & effort, this is your chance to give back!

Fill in a 15-minute survey to help us:
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Closes 16 July
www.surveymonkey.com/r/QGFMBH8?ch...

Reposted by Claudia Weber

Proud to have authored this review with brilliant people. Hope we inspire more attempts to sequence the #protist genomes that are within reach! Huge thanks to Alexandra Schoenle for leading. #ProtistsOnSky
authors.elsevier.com/sd/article/S...
ScienceDirect.com | Science, health and medical journals, full text articles and books.
authors.elsevier.com

That's roughly how my maternal grandfather who was born in Transylvania pronounced it...

Reposted by Claudia Weber

New preprint! We generate 40 new high-quality microsporidian genomes from infected arthropod hosts that were sequenced to create reference genomes by the Darwin Tree of Life project. 8 of our genomes are chromosome-level, and we’re able to generate Hi-C data for 7! 🧬
www.biorxiv.org/content/10.1...
Forty New Genomes Shed Light on Sexual Reproduction and the Origin of Tetraploidy in Microsporidia
Microsporidia are single-celled, obligately intracellular parasites with growing public health, agricultural, and economic importance. Despite this, Microsporidia remain relatively enigmatic, with man...
www.biorxiv.org

Reposted by Claudia Weber

Forty New Genomes Shed Light on Sexual Reproduction and the Origin of Tetraploidy in Microsporidia https://www.biorxiv.org/content/10.1101/2025.05.12.652816v1

68-year-old men who are on gear?

First cooperative butterfly of the year

It's a bit of a theoretical one ;)

We wrote about encoding amino acids as ambiguous observations of codons (and the resulting loss of information) here: academic.oup.com/sysbio/artic... @uperron.bsky.social

Old lettuce and no tomatoes.

I think you can keep the topology fixed in FastME if you tell it to only optimise the branch lengths

Reposted by Claudia Weber

As work ramps up, we've created a Starter pack to follow members of the consortium.

go.bsky.app/QjiXdsc

Please comment below to be added!

There was an edited extract from the O'Sullivan one in the Graun a few days ago (a bit too anecdotal for my personal liking).

'tis an enigma.

EMBL's summer recruitment closes in a few days www.embl.org/about/info/e...
EMBL International PhD Programme – Unique in the world and waiting for you!
www.embl.org

Yep, I was watching thinking "Ah, I know who this reminds me of".

Reposted by Claudia Weber

Adaptation to life on land evolved multiple times in arthropods, but what about isopods? Join us on Weds 26 Feb at 2pm (UK) to hear #ProcB author @jessthorpemas.bsky.social discuss her work on this key ecological transition. Find out more & sign up: cassyni.com/events/VVbok...

Reposted by Claudia Weber

Barking might be an option for some of them too.