Claudia C. Weber
cc7740.bsky.social
Claudia C. Weber
@cc7740.bsky.social
Molecular evolution, genomes (lots of them, preferably weird), computational models. Stockholm, Sweden (she/her)
https://github.com/claudia-c-weber
Pinned
Our paper on myxozoan genomes is out now in G3! See thread below for a brief recap (slight change of title from the preprint, same content).

Thank you also to @arunsethuraman.bsky.social for handling the manuscript and @joannamasel.bsky.social for helpful comments.

academic.oup.com/g3journal/ad...
Reposted by Claudia C. Weber
Really, really happy that our work on microsporidian genomes is now out in @plosbiology.org! A huge thank you to my coauthors, my supervisors @mblaxter.bsky.social & @marakat.bsky.social, the editors @roliroberts.bsky.social & Joseph Heitman, and the reviewers ❤️ plos.io/48HsAQJ
October 22, 2025 at 10:47 AM
Shiny wasp
June 27, 2025 at 12:18 PM
Reposted by Claudia C. Weber
If EMBL-EBI managed data resources have ever saved you time & effort, this is your chance to give back!

Fill in a 15-minute survey to help us:
🌍Demonstrate the real-world impact of our resources
🤓Understand your needs
🌟Secure continued funding

Closes 16 July
www.surveymonkey.com/r/QGFMBH8?ch...
June 16, 2025 at 10:20 AM
Hymenopteran Hotel
June 18, 2025 at 9:36 AM
Reposted by Claudia C. Weber
Proud to have authored this review with brilliant people. Hope we inspire more attempts to sequence the #protist genomes that are within reach! Huge thanks to Alexandra Schoenle for leading. #ProtistsOnSky
authors.elsevier.com/sd/article/S...
ScienceDirect.com | Science, health and medical journals, full text articles and books.
authors.elsevier.com
June 13, 2025 at 8:48 AM
Reposted by Claudia C. Weber
New preprint! We generate 40 new high-quality microsporidian genomes from infected arthropod hosts that were sequenced to create reference genomes by the Darwin Tree of Life project. 8 of our genomes are chromosome-level, and we’re able to generate Hi-C data for 7! 🧬
www.biorxiv.org/content/10.1...
Forty New Genomes Shed Light on Sexual Reproduction and the Origin of Tetraploidy in Microsporidia
Microsporidia are single-celled, obligately intracellular parasites with growing public health, agricultural, and economic importance. Despite this, Microsporidia remain relatively enigmatic, with man...
www.biorxiv.org
May 16, 2025 at 10:58 AM
Reposted by Claudia C. Weber
Forty New Genomes Shed Light on Sexual Reproduction and the Origin of Tetraploidy in Microsporidia https://www.biorxiv.org/content/10.1101/2025.05.12.652816v1
May 15, 2025 at 6:35 PM
First cooperative butterfly of the year
April 20, 2025 at 5:59 PM
Reposted by Claudia C. Weber
Our paper on myxozoan genomes is out now in G3! See thread below for a brief recap (slight change of title from the preprint, same content).

Thank you also to @arunsethuraman.bsky.social for handling the manuscript and @joannamasel.bsky.social for helpful comments.

academic.oup.com/g3journal/ad...
March 21, 2025 at 11:15 AM
Reposted by Claudia C. Weber
Excited to be part of this project! Follow the starter pack for more great repro evo researchers!
As work ramps up, we've created a Starter pack to follow members of the consortium.

go.bsky.app/QjiXdsc

Please comment below to be added!
March 21, 2025 at 4:36 PM
Our paper on myxozoan genomes is out now in G3! See thread below for a brief recap (slight change of title from the preprint, same content).

Thank you also to @arunsethuraman.bsky.social for handling the manuscript and @joannamasel.bsky.social for helpful comments.

academic.oup.com/g3journal/ad...
March 21, 2025 at 11:15 AM
Reposted by Claudia C. Weber
Adaptation to life on land evolved multiple times in arthropods, but what about isopods? Join us on Weds 26 Feb at 2pm (UK) to hear #ProcB author @jessthorpemas.bsky.social discuss her work on this key ecological transition. Find out more & sign up: cassyni.com/events/VVbok...
February 14, 2025 at 12:42 PM
Thanks to @GeneticsGSA for featuring my paper on using Variational Autoencoders to identify contamination in long-read data in the latest issue of G3: academic.oup.com/g3journal/ar...

A short thread written when the manuscript was first submitted:
bsky.app/profile/cc77...
Have long-read data and want to know what you've really sequenced, and how much of it? Reliable taxonomic labels are often scarce if the target is from a less well-explored group. Fortunately, 2D embeddings from a VAE can tease apart different organisms in read sets:

www.biorxiv.org/content/10.1...
Disentangling Cobionts and Contamination in Long-Read Genomic Data using Sequence Composition
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
November 7, 2024 at 1:58 PM
Myxozoans are tiny parasitic animals whose closest free-living relatives are jellyfish. They also haven't been extensively sequenced. However, we were lucky enough to spot some sequences in data from infected fish. After some experimenting, we got two new genomes: www.biorxiv.org/content/10.1...
Kudoa genomes from contaminated hosts reveal extensive gene order conservation and rapid sequence evolution
Myxozoans are obligate endoparasites that belong to the phylum Cnidaria. Compared to their closest free-living relatives, they have evolved highly simplified body plans and reduced genomes. Kudoa iwat...
www.biorxiv.org
November 4, 2024 at 4:16 PM
Reposted by Claudia C. Weber
Kudoa genomes from contaminated hosts reveal extensive gene order conservation and rapid sequence evolution https://www.biorxiv.org/content/10.1101/2024.11.01.621499v1
Kudoa genomes from contaminated hosts reveal extensive gene order conservation and rapid sequence evolution https://www.biorxiv.org/content/10.1101/2024.11.01.621499v1
Myxozoans are obligate endoparasites that belong to the phylum Cnidaria. Compared to their closest f
www.biorxiv.org
November 4, 2024 at 6:34 AM
Spider!
October 9, 2024 at 8:45 AM
Now out in G3: academic.oup.com/g3journal/ad... (thanks to the editors and reviewers for attention to detail and efficiency!)
August 16, 2024 at 10:53 AM
Have long-read data and want to know what you've really sequenced, and how much of it? Reliable taxonomic labels are often scarce if the target is from a less well-explored group. Fortunately, 2D embeddings from a VAE can tease apart different organisms in read sets:

www.biorxiv.org/content/10.1...
Disentangling Cobionts and Contamination in Long-Read Genomic Data using Sequence Composition
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
June 4, 2024 at 3:42 PM
Reposted by Claudia C. Weber
Disentangling Cobionts and Contamination in Long-Read Genomic Data using Sequence Composition https://www.biorxiv.org/content/10.1101/2024.05.30.596622v1
Disentangling Cobionts and Contamination in Long-Read Genomic Data using Sequence Composition https://www.biorxiv.org/content/10.1101/2024.05.30.596622v1
The recent acceleration in genome sequencing targeting previously unexplored parts of the tree of li
www.biorxiv.org
June 3, 2024 at 2:47 PM
Interested in phylogenetic methods development, and looking for a postdoc? My colleagues in Nick Goldman's group at EMBL-EBI have a position open to work on pandemic-scale methods: www.embl.org/jobs/positio... (can vouch for the working environment)
March 15, 2024 at 5:56 PM
Colourful waxcaps
December 1, 2023 at 9:57 PM
Reposted by Claudia C. Weber
✉️ Some science 🧪 buddies and I have written an open letter to the UK government, strongly opposing their “kicking woke ideology out of science” sentiments, which stand to damage the UK’s scientific standing and ability to deliver for public good.

Please read and consider signing ✍🏻

t.co/H7rNzb0wGh
Letter to Secretary of State re EDI in science
Online survey BOS
t.co
October 6, 2023 at 12:05 PM
For enthusiasts of small eukaryotes: I'll be talking about myxozoans (very small parasitic cnidarians) tomorrow at Biodiversity Genomics 2023 (10am BST). Also featured in the session: Microsporidia and nematodes.
Biodiversity Genomics 2023 - Welcome
events.venue-av.com
October 3, 2023 at 3:47 PM